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Search results 1 to 100 out of 947 for Nkx3-1

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0.561s
Type Details Score
Publication
First Author: Sciavolino PJ
Year: 1997
Journal: Dev Dyn
Title: Tissue-specific expression of murine Nkx3.1 in the male urogenital system.
Volume: 209
Issue: 1
Pages: 127-38
Publication
First Author: Bhatia-Gaur R
Year: 1999
Journal: Genes Dev
Title: Roles for Nkx3.1 in prostate development and cancer.
Volume: 13
Issue: 8
Pages: 966-77
Publication
First Author: Tanaka M
Year: 1999
Journal: Mech Dev
Title: Expression of the Nkx3.1 homobox gene during pre and postnatal development.
Volume: 85
Issue: 1-2
Pages: 179-82
Publication
First Author: Schneider A
Year: 2000
Journal: Mech Dev
Title: Targeted disruption of the Nkx3.1 gene in mice results in morphogenetic defects of minor salivary glands: parallels to glandular duct morphogenesis in prostate.
Volume: 95
Issue: 1-2
Pages: 163-74
Publication
First Author: Kim MJ
Year: 2002
Journal: Cancer Res
Title: Nkx3.1 mutant mice recapitulate early stages of prostate carcinogenesis.
Volume: 62
Issue: 11
Pages: 2999-3004
Publication
First Author: Ju JH
Year: 2006
Journal: J Mol Biol
Title: Physical and functional interactions between the prostate suppressor homeoprotein NKX3.1 and serum response factor.
Volume: 360
Issue: 5
Pages: 989-99
Publication
First Author: Wang X
Year: 2008
Journal: Dev Dyn
Title: Mouse Fem1b interacts with the Nkx3.1 homeoprotein and is required for proper male secondary sexual development.
Volume: 237
Issue: 10
Pages: 2963-72
Publication
First Author: Abdulkadir SA
Year: 2002
Journal: Mol Cell Biol
Title: Conditional loss of Nkx3.1 in adult mice induces prostatic intraepithelial neoplasia.
Volume: 22
Issue: 5
Pages: 1495-503
Publication
First Author: Kruithof-de Julio M
Year: 2013
Journal: Dev Dyn
Title: Canonical Wnt signaling regulates Nkx3.1 expression and luminal epithelial differentiation during prostate organogenesis.
Volume: 242
Issue: 10
Pages: 1160-71
Publication
First Author: Zhang H
Year: 2016
Journal: Prostate
Title: Nkx3.1 controls the DNA repair response in the mouse prostate.
Volume: 76
Issue: 4
Pages: 402-8
Publication
First Author: Ouyang X
Year: 2005
Journal: Cancer Res
Title: Loss-of-function of Nkx3.1 promotes increased oxidative damage in prostate carcinogenesis.
Volume: 65
Issue: 15
Pages: 6773-9
Publication
First Author: Kim MJ
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis.
Volume: 99
Issue: 5
Pages: 2884-9
Publication
First Author: Logan M
Year: 2013
Journal: Am J Pathol
Title: RAMP1 is a direct NKX3.1 target gene up-regulated in prostate cancer that promotes tumorigenesis.
Volume: 183
Issue: 3
Pages: 951-63
Publication
First Author: Muhlbradt E
Year: 2009
Journal: Cancer Res
Title: NKX3.1 activates expression of insulin-like growth factor binding protein-3 to mediate insulin-like growth factor-I signaling and cell proliferation.
Volume: 69
Issue: 6
Pages: 2615-22
Publication
First Author: Papachristodoulou A
Year: 2021
Journal: Cancer Discov
Title: NKX3.1 Localization to Mitochondria Suppresses Prostate Cancer Initiation.
Volume: 11
Issue: 9
Pages: 2316-2333
Publication
First Author: Anderson PD
Year: 2012
Journal: J Clin Invest
Title: Nkx3.1 and Myc crossregulate shared target genes in mouse and human prostate tumorigenesis.
Volume: 122
Issue: 5
Pages: 1907-19
Publication
First Author: Kim U
Year: 2020
Journal: Andrology
Title: Loss of glutathione peroxidase 3 induces ROS and contributes to prostatic hyperplasia in Nkx3.1 knockout mice.
Volume: 8
Issue: 5
Pages: 1486-1493
Publication
First Author: Martinez EE
Year: 2012
Journal: PLoS One
Title: Antioxidant treatment promotes prostate epithelial proliferation in Nkx3.1 mutant mice.
Volume: 7
Issue: 10
Pages: e46792
Publication
First Author: Iwata T
Year: 2010
Journal: PLoS One
Title: MYC overexpression induces prostatic intraepithelial neoplasia and loss of Nkx3.1 in mouse luminal epithelial cells.
Volume: 5
Issue: 2
Pages: e9427
Publication
First Author: Herbrand H
Year: 2002
Journal: Mech Dev
Title: Transcription factors Nkx3.1 and Nkx3.2 (Bapx1) play an overlapping role in sclerotomal development of the mouse.
Volume: 117
Issue: 1-2
Pages: 217-24
Publication
First Author: Magee JA
Year: 2003
Journal: Cancer Cell
Title: Haploinsufficiency at the Nkx3.1 locus. A paradigm for stochastic, dosage-sensitive gene regulation during tumor initiation.
Volume: 3
Issue: 3
Pages: 273-83
Publication
First Author: Gary B
Year: 2004
Journal: Am J Pathol
Title: Interaction of Nkx3.1 and p27kip1 in prostate tumor initiation.
Volume: 164
Issue: 5
Pages: 1607-14
Publication
First Author: Song H
Year: 2009
Journal: Oncogene
Title: Loss of Nkx3.1 leads to the activation of discrete downstream target genes during prostate tumorigenesis.
Volume: 28
Issue: 37
Pages: 3307-19
Publication  
First Author: Sharma P
Year: 2013
Journal: Mol Cancer
Title: Id4 deficiency attenuates prostate development and promotes PIN-like lesions by regulating androgen receptor activity and expression of NKX3.1 and PTEN.
Volume: 12
Pages: 67
Publication
First Author: Zhang Y
Year: 2008
Journal: Exp Biol Med (Maywood)
Title: Structural and functional analysis of domains mediating interaction between the bagpipe homologue, Nkx3.1 and serum response factor.
Volume: 233
Issue: 3
Pages: 297-309
Publication
First Author: Sun Q
Year: 2009
Journal: J Biol Chem
Title: Myocardin-dependent activation of the CArG box-rich smooth muscle gamma-actin gene: preferential utilization of a single CArG element through functional association with the NKX3.1 homeodomain protein.
Volume: 284
Issue: 47
Pages: 32582-90
Publication
First Author: Shen MM
Year: 2003
Journal: Dev Dyn
Title: Roles of the Nkx3.1 homeobox gene in prostate organogenesis and carcinogenesis.
Volume: 228
Issue: 4
Pages: 767-78
Publication
First Author: Lei Q
Year: 2006
Journal: Cancer Cell
Title: NKX3.1 stabilizes p53, inhibits AKT activation, and blocks prostate cancer initiation caused by PTEN loss.
Volume: 9
Issue: 5
Pages: 367-78
Publication
First Author: Simmons SO
Year: 2006
Journal: Biochem J
Title: Nkx3.1 binds and negatively regulates the transcriptional activity of Sp-family members in prostate-derived cells.
Volume: 393
Issue: Pt 1
Pages: 397-409
Publication
First Author: Khalili M
Year: 2010
Journal: Am J Pathol
Title: Loss of Nkx3.1 expression in bacterial prostatitis: a potential link between inflammation and neoplasia.
Volume: 176
Issue: 5
Pages: 2259-68
Publication
First Author: Mai T
Year: 2018
Journal: Nat Cell Biol
Title: NKX3-1 is required for induced pluripotent stem cell reprogramming and can replace OCT4 in mouse and human iPSC induction.
Volume: 20
Issue: 8
Pages: 900-908
Publication
First Author: Bowen C
Year: 2019
Journal: Cancer Res
Title: Loss of PTEN Accelerates NKX3.1 Degradation to Promote Prostate Cancer Progression.
Volume: 79
Issue: 16
Pages: 4124-4134
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication  
First Author: Le Magnen C
Year: 2018
Journal: Dis Model Mech
Title: Cooperation of loss of NKX3.1 and inflammation in prostate cancer initiation.
Volume: 11
Issue: 11
Publication
First Author: Wang X
Year: 2009
Journal: Nature
Title: A luminal epithelial stem cell that is a cell of origin for prostate cancer.
Volume: 461
Issue: 7263
Pages: 495-500
Publication
First Author: Bowen C
Year: 2020
Journal: Cancer Res
Title: CRISPR/Cas9-Mediated Point Mutation in Nkx3.1 Prolongs Protein Half-Life and Reverses Effects Nkx3.1 Allelic Loss.
Volume: 80
Issue: 21
Pages: 4805-4814
Publication
First Author: Provot S
Year: 2006
Journal: Development
Title: Nkx3.2/Bapx1 acts as a negative regulator of chondrocyte maturation.
Volume: 133
Issue: 4
Pages: 651-62
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Stanfel MN
Year: 2006
Journal: Genesis
Title: Expression of an Nkx3.1-CRE gene using ROSA26 reporter mice.
Volume: 44
Issue: 11
Pages: 550-5
Publication
First Author: Ittmann M
Year: 2013
Journal: Cancer Res
Title: Animal models of human prostate cancer: the consensus report of the New York meeting of the Mouse Models of Human Cancers Consortium Prostate Pathology Committee.
Volume: 73
Issue: 9
Pages: 2718-36
Publication    
First Author: Chua CW
Year: 2018
Journal: Elife
Title: Differential requirements of androgen receptor in luminal progenitors during prostate regeneration and tumor initiation.
Volume: 7
Publication
First Author: Tanaka M
Year: 2000
Journal: Dev Dyn
Title: Nkx3.1, a murine homolog of Ddrosophila bagpipe, regulates epithelial ductal branching and proliferation of the prostate and palatine glands.
Volume: 219
Issue: 2
Pages: 248-60
Publication
First Author: Zhu Y
Year: 2023
Journal: Sci Immunol
Title: Targeting the chromatin effector Pygo2 promotes cytotoxic T cell responses and overcomes immunotherapy resistance in prostate cancer.
Volume: 8
Issue: 81
Pages: eade4656
Publication
First Author: Aytes A
Year: 2014
Journal: Cancer Cell
Title: Cross-species regulatory network analysis identifies a synergistic interaction between FOXM1 and CENPF that drives prostate cancer malignancy.
Volume: 25
Issue: 5
Pages: 638-651
Publication
First Author: Dutta A
Year: 2016
Journal: Science
Title: Identification of an NKX3.1-G9a-UTY transcriptional regulatory network that controls prostate differentiation.
Volume: 352
Issue: 6293
Pages: 1576-80
Publication
First Author: Gao H
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A critical role for p27kip1 gene dosage in a mouse model of prostate carcinogenesis.
Volume: 101
Issue: 49
Pages: 17204-9
Publication
First Author: Damaschke NA
Year: 2017
Journal: Cancer Res
Title: Loss of Igf2 Gene Imprinting in Murine Prostate Promotes Widespread Neoplastic Growth.
Volume: 77
Issue: 19
Pages: 5236-5247
Publication
First Author: Linn DE
Year: 2015
Journal: PLoS One
Title: Genetic interaction between Tmprss2-ERG gene fusion and Nkx3.1-loss does not enhance prostate tumorigenesis in mouse models.
Volume: 10
Issue: 3
Pages: e0120628
Publication
First Author: Thomsen MK
Year: 2010
Journal: Cancer Res
Title: SOX9 elevation in the prostate promotes proliferation and cooperates with PTEN loss to drive tumor formation.
Volume: 70
Issue: 3
Pages: 979-87
Publication
First Author: Valkenburg KC
Year: 2014
Journal: Prostate
Title: Activation of Wnt/β-catenin signaling in a subpopulation of murine prostate luminal epithelial cells induces high grade prostate intraepithelial neoplasia.
Volume: 74
Issue: 15
Pages: 1506-20
Publication
First Author: Patel R
Year: 2020
Journal: Cancer Res
Title: Activation of β-Catenin Cooperates with Loss of Pten to Drive AR-Independent Castration-Resistant Prostate Cancer.
Volume: 80
Issue: 3
Pages: 576-590
Publication  
First Author: Talos F
Year: 2017
Journal: Nat Commun
Title: A computational systems approach identifies synergistic specification genes that facilitate lineage conversion to prostate tissue.
Volume: 8
Pages: 14662
Publication
First Author: Vinall RL
Year: 2012
Journal: Dis Model Mech
Title: Initiation of prostate cancer in mice by Tp53R270H: evidence for an alternative molecular progression.
Volume: 5
Issue: 6
Pages: 914-20
Publication
First Author: Thomsen MK
Year: 2008
Journal: Dev Biol
Title: Sox9 is required for prostate development.
Volume: 316
Issue: 2
Pages: 302-11
Publication
First Author: Mitrofanova A
Year: 2015
Journal: Cell Rep
Title: Predicting Drug Response in Human Prostate Cancer from Preclinical Analysis of In Vivo Mouse Models.
Volume: 12
Issue: 12
Pages: 2060-71
Publication
First Author: Wang J
Year: 2012
Journal: Cancer Res
Title: B-Raf activation cooperates with PTEN loss to drive c-Myc expression in advanced prostate cancer.
Volume: 72
Issue: 18
Pages: 4765-76
Publication
First Author: Floc'h N
Year: 2012
Journal: Cancer Res
Title: Dual targeting of the Akt/mTOR signaling pathway inhibits castration-resistant prostate cancer in a genetically engineered mouse model.
Volume: 72
Issue: 17
Pages: 4483-93
Publication
First Author: Yende AS
Year: 2023
Journal: Oncogene
Title: TRIM28 promotes luminal cell plasticity in a mouse model of prostate cancer.
Volume: 42
Issue: 17
Pages: 1347-1359
Publication
First Author: Zou M
Year: 2017
Journal: Cancer Discov
Title: Transdifferentiation as a Mechanism of Treatment Resistance in a Mouse Model of Castration-Resistant Prostate Cancer.
Volume: 7
Issue: 7
Pages: 736-749
Publication
First Author: Santanam U
Year: 2016
Journal: Genes Dev
Title: Atg7 cooperates with Pten loss to drive prostate cancer tumor growth.
Volume: 30
Issue: 4
Pages: 399-407
Publication
First Author: Gao D
Year: 2016
Journal: PLoS One
Title: A Tmprss2-CreERT2 Knock-In Mouse Model for Cancer Genetic Studies on Prostate and Colon.
Volume: 11
Issue: 8
Pages: e0161084
Publication
First Author: Wang ZA
Year: 2013
Journal: Nat Cell Biol
Title: Lineage analysis of basal epithelial cells reveals their unexpected plasticity and supports a cell-of-origin model for prostate cancer heterogeneity.
Volume: 15
Issue: 3
Pages: 274-83
Publication
First Author: Chua CW
Year: 2014
Journal: Nat Cell Biol
Title: Single luminal epithelial progenitors can generate prostate organoids in culture.
Volume: 16
Issue: 10
Pages: 951-61, 1-4
Publication
First Author: Teinturier R
Year: 2021
Journal: Oncogene
Title: Men1 disruption in Nkx3.1-deficient mice results in ARlow/CD44+ microinvasive carcinoma development with the dysregulated AR pathway.
Volume: 40
Issue: 6
Pages: 1118-1127
Publication  
First Author: Yoo YA
Year: 2016
Journal: Nat Commun
Title: Bmi1 marks distinct castration-resistant luminal progenitor cells competent for prostate regeneration and tumour initiation.
Volume: 7
Pages: 12943
Publication
First Author: Aytes A
Year: 2018
Journal: Nat Commun
Title: NSD2 is a conserved driver of metastatic prostate cancer progression.
Volume: 9
Issue: 1
Pages: 5201
Publication  
First Author: Xie Q
Year: 2017
Journal: Nat Commun
Title: Dissecting cell-type-specific roles of androgen receptor in prostate homeostasis and regeneration through lineage tracing.
Volume: 8
Pages: 14284
Publication
First Author: Aytes A
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ETV4 promotes metastasis in response to activation of PI3-kinase and Ras signaling in a mouse model of advanced prostate cancer.
Volume: 110
Issue: 37
Pages: E3506-15
Gene
Type: gene
Organism: human
Publication
First Author: Carson JA
Year: 2000
Journal: J Biol Chem
Title: The smooth muscle gamma-actin gene promoter is a molecular target for the mouse bagpipe homologue, mNkx3-1, and serum response factor.
Volume: 275
Issue: 50
Pages: 39061-72
Publication
First Author: Bethel CR
Year: 2007
Journal: Prostate
Title: Loss of Nkx3.1 expression in the transgenic adenocarcinoma of mouse prostate model.
Volume: 67
Issue: 16
Pages: 1740-50
Publication
First Author: Keil KP
Year: 2012
Journal: Differentiation
Title: Visualization and quantification of mouse prostate development by in situ hybridization.
Volume: 84
Issue: 3
Pages: 232-9
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1686019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1C
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1686019
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1D
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116917
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:5430518
Age: embryonic day 10.5
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: Not shown E10.5
Detected: true
Specimen Num: 5
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3116920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:5430518
Age: embryonic day 12.5
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: Not shown E12.5
Detected: true
Specimen Num: 6
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1C
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1C
Detected: true
Specimen Num: 3
GXD Expression  
Assay Type: In situ reporter (knock in)
Annotation Date: 2012-08-07
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1618419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:5430518
Age: embryonic day 11.5
Image: 1D
Note: Nkx3.1 expression domains are indistinguishable in heterozygous and homozygous Nkx3.2 mutants.
Specimen Label: 1D
Detected: true
Specimen Num: 4
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190900
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nkx3-1
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190900
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nkx3-1
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190900
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Nkx3-1
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190900
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Nkx3-1
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190900
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Nkx3-1
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190900
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Nkx3-1
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:6179085
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190900
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Nkx3-1
Detected: false
Specimen Num: 7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory