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Search results 1 to 100 out of 997 for Nkx6-1

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Type Details Score
Publication
11076772 | J:65594
First Author: Sander M
Year: 2000
Journal: Development
Title: Homeobox gene Nkx6.1 lies downstream of Nkx2.2 in the major pathway of beta-cell formation in the pancreas.
Volume: 127
Issue: 24
Pages: 5533-40
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Publication
23382704 | J:195153
First Author: Schaffer AE
Year: 2013
Journal: PLoS Genet
Title: Nkx6.1 controls a gene regulatory network required for establishing and maintaining pancreatic Beta cell identity.
Volume: 9
Issue: 1
Pages: e1003274
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Publication
14534138 | J:86051
First Author: Müller M
Year: 2003
Journal: Development
Title: Nkx6.1 controls migration and axon pathfinding of cranial branchio-motoneurons.
Volume: 130
Issue: 23
Pages: 5815-26
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Publication
19592574 | J:152847
First Author: Prakash N
Year: 2009
Journal: Development
Title: Nkx6-1 controls the identity and fate of red nucleus and oculomotor neurons in the mouse midbrain.
Volume: 136
Issue: 15
Pages: 2545-55
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Publication
14602683 | J:87224
First Author: Liu R
Year: 2003
Journal: Development
Title: Region-specific and stage-dependent regulation of Olig gene expression and oligodendrogenesis by Nkx6.1 homeodomain transcription factor.
Volume: 130
Issue: 25
Pages: 6221-31
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Publication
21964593 | J:234595
First Author: Schaffer AE
Year: 2011
Journal: Mol Endocrinol
Title: Transgenic overexpression of the transcription factor Nkx6.1 in β-cells of mice does not increase β-cell proliferation, β-cell mass, or improve glucose clearance.
Volume: 25
Issue: 11
Pages: 1904-14
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Publication
18215620 | J:132705
First Author: De Marco Garcia NV
Year: 2008
Journal: Neuron
Title: Early motor neuron pool identity and muscle nerve trajectory defined by postmitotic restrictions in Nkx6.1 activity.
Volume: 57
Issue: 2
Pages: 217-31
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Publication
32008054 | J:289417
First Author: Zhang FF
Year: 2020
Journal: Diabetologia
Title: Obesity-induced reduced expression of the lncRNA ROIT impairs insulin transcription by downregulation of Nkx6.1 methylation.
Volume: 63
Issue: 4
Pages: 811-824
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Publication
10970877 | J:64376
First Author: Sander M
Year: 2000
Journal: Genes Dev
Title: Ventral neural patterning by Nkx homeobox genes: Nkx6.1 controls somatic motor neuron and ventral interneuron fates.
Volume: 14
Issue: 17
Pages: 2134-9
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Publication
17537793 | J:122518
First Author: Nelson SB
Year: 2007
Journal: Development
Title: The transcription factors Nkx6.1 and Nkx6.2 possess equivalent activities in promoting beta-cell fate specification in Pdx1+ pancreatic progenitor cells.
Volume: 134
Issue: 13
Pages: 2491-500
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Publication
24035389 | J:203800
First Author: Taylor BL
Year: 2013
Journal: Cell Rep
Title: Nkx6.1 is essential for maintaining the functional state of pancreatic beta cells.
Volume: 4
Issue: 6
Pages: 1262-75
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Publication
25285789 | J:223471
First Author: Zhao X
Year: 2014
Journal: PLoS One
Title: Control of astrocyte progenitor specification, migration and maturation by Nkx6.1 homeodomain transcription factor.
Volume: 9
Issue: 10
Pages: e109171
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Publication
18347078 | J:137140
First Author: Hald J
Year: 2008
Journal: J Histochem Cytochem
Title: Generation and characterization of Ptf1a antiserum and localization of Ptf1a in relation to Nkx6.1 and Pdx1 during the earliest stages of mouse pancreas development.
Volume: 56
Issue: 6
Pages: 587-95
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Publication
20549744 | J:161205
First Author: Moreno-Bravo JA
Year: 2010
Journal: Dev Dyn
Title: Dynamic expression patterns of Nkx6.1 and Nkx6.2 in the developing mes-diencephalic basal plate.
Volume: 239
Issue: 7
Pages: 2094-101
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Publication
33810480 | J:307544
 
First Author: Burtscher I
Year: 2021
Journal: Int J Mol Sci
Title: Generation of a Novel Nkx6-1 Venus Fusion Reporter Mouse Line.
Volume: 22
Issue: 7
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Protein Coding Gene
MGI:1206039 | Nkx6-1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
15944193 | J:98770
First Author: Henseleit KD
Year: 2005
Journal: Development
Title: NKX6 transcription factor activity is required for alpha- and beta-cell development in the pancreas.
Volume: 132
Issue: 13
Pages: 3139-49
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: There is strong staining in the mantle zone of the AVH and posterior ID. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior ID.
Specimen Label: Nkx6-1 - E12.5
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: There is strong staining in the mantle zone of the AVH and posterior ID. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior ID.
Specimen Label: Nkx6-1 - E14.5
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: There is very strong staining in the mantle zone of the SCH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the PVH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Label: Nkx6-1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450758
Age: embryonic day 11.5
Image: Nkx6-1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Label: Nkx6-1 - E11.5
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:5586704
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1750321
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:6449819
Age: embryonic day 13.5
Image: S1 E13.5 Nkx6.1
Note: Expression overlaps with that of Myt1.
Specimen Label: S1 E13.5 Nkx6.1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450758
Age: embryonic day 11.5
Image: Nkx6-1 - E11.5
Note: There is strong staining in the VZ of the AVH. Staining is either absent or ubiquitous in the VZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, anterior & posterior IDs, premam, mam & supramam zones & the TT.
Specimen Label: Nkx6-1 - E11.5
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: There is strong staining in the ventricular zone of the AVH and anterior ID. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and posterior ID.
Specimen Label: Nkx6-1 - E12.5
Detected: true
Specimen Num: 2
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•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: There is strong staining in the ventricular zone of the AVH. Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei and anterior and posterior IDs.
Specimen Label: Nkx6-1 - E14.5
Detected: true
Specimen Num: 3
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•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: There is very strong staining in the VZ of the SCH nucleus, strong staining in the AVH & moderate staining in the VMH nucleus. Staining is either absent or ubiquitous in the VZ of the dorsal & ventral POAs, the PVH, DMH & ARH nuclei, the DAH & the PH.
Specimen Label: Nkx6-1 - E16.5
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:7279090
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7279118
Age: embryonic day 10.5
Image: S6B NKX6.1 Control
Specimen Label: S6B NKX6.1 Control
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7279090
Assay Type: Immunohistochemistry
Annotation Date: 2022-05-19
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:7279118
Age: embryonic day 10.5
Image: S6B NKX6.1 Mosmo-/-
Note: Authors report normal neural tube patterning
Specimen Label: S6B NKX6.1 Mosmo-/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450758
Age: embryonic day 11.5
Image: Nkx6-1 - E11.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Specimen Label: Nkx6-1 - E11.5
Specimen Num: 1
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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•
GXD Expression
GXD Expression
Probe: MGI:5586704
Assay Type: Immunohistochemistry
Annotation Date: 2020-08-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3292723
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:6449819
Age: embryonic day 15.5
Image: S1 E15.5 Nkx6.1
Note: Expression overlaps with that of Myt1.
Specimen Label: S1 E15.5 Nkx6.1
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
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•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Nkx6-1 - E12.5
Specimen Num: 2
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•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Nkx6-1 - E14.5
Specimen Num: 3
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•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Label: Nkx6-1 - E16.5
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450758
Age: embryonic day 11.5
Image: Nkx6-1 - E11.5
Note: There is strong staining in the MZ of the AVH & posterior ID. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, prethalamus, dorsal & ventral POAs, the PVH, VMH & ARH nuclei, anterior ID, the premam, mam & supramam zones & the TT.
Specimen Label: Nkx6-1 - E11.5
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450758
Age: embryonic day 12.5
Image: Nkx6-1 - E12.5
Note: There is strong staining in the mantle zone of the prethalamus. Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus.
Specimen Label: Nkx6-1 - E12.5
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450758
Age: embryonic day 14.5
Image: Nkx6-1 - E14.5
Note: There is very strong staining in the mantle zone of the dorsal thalamus and strong staining in the prethalamus.
Specimen Label: Nkx6-1 - E14.5
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
Probe: MGI:4442717
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450758
Age: embryonic day 16.5
Image: Nkx6-1 - E16.5
Note: There is very strong staining in the mantle zone of the dorsal thalamus and moderate staining in the prethalamus.
Specimen Label: Nkx6-1 - E16.5
Detected: true
Specimen Num: 4
•
•
•
•
•
Publication
10938085 | J:65512
First Author: Watada H
Year: 2000
Journal: J Biol Chem
Title: Transcriptional and translational regulation of beta-cell differentiation factor Nkx6.1.
Volume: 275
Issue: 44
Pages: 34224-30
•
•
•
•
•
Publication
16326147 | J:104158
First Author: Alanentalo T
Year: 2006
Journal: Gene Expr Patterns
Title: Cloning and analysis of Nkx6.3 during CNS and gastrointestinal development.
Volume: 6
Issue: 2
Pages: 162-70
•
•
•
•
•
Publication
16297379 | J:104952
First Author: Pedersen JK
Year: 2005
Journal: Dev Biol
Title: Endodermal expression of Nkx6 genes depends differentially on Pdx1.
Volume: 288
Issue: 2
Pages: 487-501
•
•
•
•
•
Publication
10903178 | J:63215
First Author: Schwitzgebel VM
Year: 2000
Journal: Development
Title: Expression of neurogenin3 reveals an islet cell precursor population in the pancreas.
Volume: 127
Issue: 16
Pages: 3533-42
•
•
•
•
•
Publication
31691004 | J:299374
First Author: Padula SL
Year: 2019
Journal: Hum Genet
Title: High-throughput transcriptome analysis reveals that the loss of Pten activates a novel NKX6-1/RASGRP1 regulatory module to rescue microphthalmia caused by Fgfr2-deficient lenses.
Volume: 138
Issue: 11-12
Pages: 1391-1407
•
•
•
•
•
Publication
18455991 | J:145299
First Author: Hochstim C
Year: 2008
Journal: Cell
Title: Identification of positionally distinct astrocyte subtypes whose identities are specified by a homeodomain code.
Volume: 133
Issue: 3
Pages: 510-22
•
•
•
•
•
Publication
25369423 | J:237449
First Author: Francius C
Year: 2015
Journal: Dev Neurobiol
Title: Genetic dissection of Gata2 selective functions during specification of V2 interneurons in the developing spinal cord.
Volume: 75
Issue: 7
Pages: 721-37
•
•
•
•
•
Publication
33195252 | J:309045
 
First Author: García-Guillén IM
Year: 2020
Journal: Front Cell Dev Biol
Title: Netrin-1/DCC Signaling Differentially Regulates the Migration of Pax7, Nkx6.1, Irx2, Otp, and Otx2 Cell Populations in the Developing Interpeduncular Nucleus.
Volume: 8
Pages: 588851
•
•
•
•
•
Publication
19123929 | J:160734
 
First Author: Agalliu D
Year: 2009
Journal: Neural Dev
Title: Heterogeneity in the developmental potential of motor neuron progenitors revealed by clonal analysis of single cells in vitro.
Volume: 4
Pages: 2
•
•
•
•
•
Publication
11390667 | J:69975
First Author: Cai J
Year: 2001
Journal: Mol Cell Biol
Title: Mice lacking the Nkx6.2 (Gtx) homeodomain transcription factor develop and reproduce normally.
Volume: 21
Issue: 13
Pages: 4399-403
•
•
•
•
•
Publication
15629701 | J:95822
First Author: Cai J
Year: 2005
Journal: Neuron
Title: Generation of oligodendrocyte precursor cells from mouse dorsal spinal cord independent of Nkx6 regulation and Shh signaling.
Volume: 45
Issue: 1
Pages: 41-53
•
•
•
•
•
Publication
30177510 | J:266544
 
First Author: Kim J
Year: 2018
Journal: Development
Title: Rnf220 cooperates with Zc4h2 to specify spinal progenitor domains.
Volume: 145
Issue: 17
•
•
•
•
•
Publication
15629702 | J:98428
First Author: Vallstedt A
Year: 2005
Journal: Neuron
Title: Multiple dorsoventral origins of oligodendrocyte generation in the spinal cord and hindbrain.
Volume: 45
Issue: 1
Pages: 55-67
•
•
•
•
•
Publication
12874134 | J:84976
First Author: Pattyn A
Year: 2003
Journal: Development
Title: Complementary roles for Nkx6 and Nkx2 class proteins in the establishment of motoneuron identity in the hindbrain.
Volume: 130
Issue: 17
Pages: 4149-59
•
•
•
•
•
Publication
22071102 | J:178678
First Author: Karus M
Year: 2011
Journal: Development
Title: The extracellular matrix molecule tenascin C modulates expression levels and territories of key patterning genes during spinal cord astrocyte specification.
Volume: 138
Issue: 24
Pages: 5321-31
•
•
•
•
•
Publication
25277396 | J:252878
First Author: Taylor BL
Year: 2015
Journal: Diabetes
Title: Postnatal β-cell proliferation and mass expansion is dependent on the transcription factor Nkx6.1.
Volume: 64
Issue: 3
Pages: 897-903
•
•
•
•
•
Publication
18586225 | J:139734
 
First Author: Hafler BP
Year: 2008
Journal: Brain Res
Title: Expression and function of Nkx6.3 in vertebrate hindbrain.
Volume: 1222
Pages: 42-50
•
•
•
•
•
Publication
23863625 | J:201414
First Author: Guo S
Year: 2013
Journal: J Clin Invest
Title: Inactivation of specific β cell transcription factors in type 2 diabetes.
Volume: 123
Issue: 8
Pages: 3305-16
•
•
•
•
•
Publication
17026983 | J:119875
First Author: Lebel M
Year: 2007
Journal: Dev Biol
Title: Gli2 and Gli3 play distinct roles in the dorsoventral patterning of the mouse hindbrain.
Volume: 302
Issue: 1
Pages: 345-55
•
•
•
•
•
Publication
22461559 | J:184016
First Author: Afelik S
Year: 2012
Journal: Development
Title: Notch-mediated patterning and cell fate allocation of pancreatic progenitor cells.
Volume: 139
Issue: 10
Pages: 1744-53
•
•
•
•
•
Publication
24706823 | J:208626
First Author: Tessem JS
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Nkx6.1 regulates islet β-cell proliferation via Nr4a1 and Nr4a3 nuclear receptors.
Volume: 111
Issue: 14
Pages: 5242-7
•
•
•
•
•
Gene
4825 | NKX6-1
Type: gene
Organism: human
•
•
•
•
•
Publication
9119408 | J:39416
First Author: Inoue H
Year: 1997
Journal: Genomics
Title: Isolation, characterization, and chromosomal mapping of the human Nkx6.1 gene (NKX6A), a new pancreatic islet homeobox gene.
Volume: 40
Issue: 2
Pages: 367-70
•
•
•
•
•
Publication
12528188 | J:82481
First Author: Fu H
Year: 2003
Journal: J Comp Neurol
Title: Molecular mapping of the origin of postnatal spinal cord ependymal cells: evidence that adult ependymal cells are derived from Nkx6.1+ ventral neural progenitor cells.
Volume: 456
Issue: 3
Pages: 237-44
•
•
•
•
•
Publication
26293298 | J:225353
First Author: Nishi Y
Year: 2015
Journal: Development
Title: A direct fate exclusion mechanism by Sonic hedgehog-regulated transcriptional repressors.
Volume: 142
Issue: 19
Pages: 3286-93
•
•
•
•
•
Publication
16401696 | J:226237
First Author: Pedersen IL
Year: 2006
Journal: J Histochem Cytochem
Title: Generation and characterization of monoclonal antibodies against the transcription factor Nkx6.1.
Volume: 54
Issue: 5
Pages: 567-74
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380673
Age: embryonic day 9.5
Note: Expression in ventral neural tube.
Specimen Label: S2A Nkx6.1 WT
Detected: true
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380673
Age: embryonic day 9.5
Note: Expression in ventral neural tube.
Specimen Label: S2A Nkx6.1 bromi
Detected: true
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380673
Age: embryonic day 9.5
Specimen Label: S2A Nkx6.1 Ptch1
Detected: true
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616415
Pattern: Regionally restricted
Stage: TS15
Assay Id: MGI:7380673
Age: embryonic day 9.5
Note: Dorsal border of expression shited compared to wild type.
Specimen Label: S2A Nkx6.1 bromi,Ptch1
Detected: true
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380673
Age: embryonic day 10.5
Note: Expression in ventral neural tube.
Specimen Label: S2C Nkx6.1 WT
Detected: true
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
   
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380673
Age: embryonic day 10.5
Specimen Label: S2C Nkx6.1 bromi
Detected: true
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380673
Age: embryonic day 10.5
Note: Expression domain shifted compared to wild type.
Specimen Label: S2C Nkx6.1 Rab23opb2
Detected: true
Specimen Num: 7
•
•
•
•
•
GXD Expression
GXD Expression
 
Probe: MGI:7380628
Assay Type: Immunohistochemistry
Annotation Date: 2022-11-09
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1616417
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:7380673
Age: embryonic day 10.5
Note: Authors report same dorsalized phenotype as in bromi single mutants.
Specimen Label: S2C Nkx6.1 bromi,Rab23opb2
Detected: true
Specimen Num: 8
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190901
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Nkx6-1
Detected: false
Specimen Num: 1
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190901
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Nkx6-1
Detected: false
Specimen Num: 2
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190901
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Nkx6-1
Detected: false
Specimen Num: 3
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190901
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Nkx6-1
Detected: false
Specimen Num: 4
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190901
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Nkx6-1
Detected: false
Specimen Num: 5
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190901
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Nkx6-1
Detected: false
Specimen Num: 6
•
•
•
•
•
GXD Expression
GXD Expression
     
Probe: MGI:6179088
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190901
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Nkx6-1
Detected: false
Specimen Num: 7
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0027461 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0029795 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0029761 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0029707 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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