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Search results 1 to 100 out of 184 for Nlgn1

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0.056s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Neuroligin-1 (NLGN1) belongs to the neuroligins (NLGNs) family, whose members interact with the neurexin family members and are involved in the modulation of synaptic transmission. NLGN1 is a cell adhesion protein that is essential for the formation and consolidation of synaptic connectivity and is involved in vascular development []. It is localised on excitatory (glutamatergic) synapses []. It has been linked to memory formation []and autism [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Samarelli AV
Year: 2014
Journal: J Biol Chem
Title: Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
Volume: 289
Issue: 28
Pages: 19466-76
Publication
First Author: Blundell J
Year: 2010
Journal: J Neurosci
Title: Neuroligin-1 deletion results in impaired spatial memory and increased repetitive behavior.
Volume: 30
Issue: 6
Pages: 2115-29
Protein
Organism: Mus musculus
Length: 814  
Fragment?: false
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Jeong J
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: PSD-95 binding dynamically regulates NLGN1 trafficking and function.
Volume: 116
Issue: 24
Pages: 12035-12044
Protein
Organism: Mus musculus
Length: 117  
Fragment?: true
Publication
First Author: Song JY
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Neuroligin 1 is a postsynaptic cell-adhesion molecule of excitatory synapses.
Volume: 96
Issue: 3
Pages: 1100-5
Protein
Organism: Mus musculus
Length: 106  
Fragment?: false
Publication
First Author: Maćkowiak M
Year: 2014
Journal: Pharmacol Rep
Title: Neuroligins, synapse balance and neuropsychiatric disorders.
Volume: 66
Issue: 5
Pages: 830-5
Protein
Organism: Mus musculus
Length: 554  
Fragment?: true
Protein
Organism: Mus musculus
Length: 843  
Fragment?: false
Protein
Organism: Mus musculus
Length: 814  
Fragment?: false
Publication
First Author: Bie B
Year: 2014
Journal: Nat Neurosci
Title: Epigenetic suppression of neuroligin 1 underlies amyloid-induced memory deficiency.
Volume: 17
Issue: 2
Pages: 223-31
Publication    
First Author: Letellier M
Year: 2020
Journal: Elife
Title: Optogenetic control of excitatory post-synaptic differentiation through neuroligin-1 tyrosine phosphorylation.
Volume: 9
Publication  
First Author: Zhao JY
Year: 2018
Journal: Neuroscience
Title: Activity-dependent Synaptic Recruitment of Neuroligin 1 in Spinal Dorsal Horn Contributed to Inflammatory Pain.
Volume: 388
Pages: 1-10
Publication
First Author: Nakanishi M
Year: 2017
Journal: PLoS Genet
Title: Functional significance of rare neuroligin 1 variants found in autism.
Volume: 13
Issue: 8
Pages: e1006940
Publication  
First Author: Belanger-Nelson E
Year: 2015
Journal: Neuroscience
Title: Brain hemodynamic response to somatosensory stimulation in Neuroligin-1 knockout mice.
Volume: 289
Pages: 242-50
Publication
First Author: Tristán-Clavijo E
Year: 2015
Journal: Neurobiol Aging
Title: A truncating mutation in Alzheimer's disease inactivates neuroligin-1 synaptic function.
Volume: 36
Issue: 12
Pages: 3171-3175
Publication
First Author: Dufort-Gervais J
Year: 2020
Journal: Sci Rep
Title: Neuroligin-1 is altered in the hippocampus of Alzheimer's disease patients and mouse models, and modulates the toxicity of amyloid-beta oligomers.
Volume: 10
Issue: 1
Pages: 6956
Publication
First Author: Chanda S
Year: 2017
Journal: J Neurosci
Title: Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.
Volume: 37
Issue: 29
Pages: 6816-6836
Publication      
First Author: Chmielewska JJ
Year: 2018
Journal: Mol Neurobiol
Title: Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
Publication
First Author: Südhof TC
Year: 2017
Journal: Cell
Title: Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Volume: 171
Issue: 4
Pages: 745-769
Publication
First Author: Zhang B
Year: 2015
Journal: Neuron
Title: Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.
Volume: 87
Issue: 4
Pages: 781-96
Publication
First Author: Zhang B
Year: 2018
Journal: J Exp Med
Title: Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Volume: 215
Issue: 6
Pages: 1543-1553
Publication
First Author: Zhang B
Year: 2016
Journal: J Neurosci
Title: Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.
Volume: 36
Issue: 35
Pages: 9070-83
Publication      
First Author: Sudhof TC
Year: 2008
Journal: MGI Direct Data Submission
Title: Generation of a Nlgn1 null allele
Publication
First Author: Wu X
Year: 2019
Journal: Neuron
Title: Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.
Volume: 102
Issue: 3
Pages: 621-635.e3
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Scheiffele P
Year: 2000
Journal: Cell
Title: Neuroligin expressed in nonneuronal cells triggers presynaptic development in contacting axons.
Volume: 101
Issue: 6
Pages: 657-69
Publication
First Author: El Helou J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Neuroligin-1 links neuronal activity to sleep-wake regulation.
Volume: 110
Issue: 24
Pages: 9974-9
Publication
First Author: Chen X
Year: 2008
Journal: Nat Struct Mol Biol
Title: Structural basis for synaptic adhesion mediated by neuroligin-neurexin interactions.
Volume: 15
Issue: 1
Pages: 50-6
Publication
First Author: Jung SY
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Input-specific synaptic plasticity in the amygdala is regulated by neuroligin-1 via postsynaptic NMDA receptors.
Volume: 107
Issue: 10
Pages: 4710-5
Publication
First Author: Kwon HB
Year: 2012
Journal: Nat Neurosci
Title: Neuroligin-1-dependent competition regulates cortical synaptogenesis and synapse number.
Volume: 15
Issue: 12
Pages: 1667-74
Publication
First Author: Zeidan A
Year: 2012
Journal: PLoS One
Title: Neuroligin-1 loss is associated with reduced tenacity of excitatory synapses.
Volume: 7
Issue: 7
Pages: e42314
Publication
First Author: Mondin M
Year: 2011
Journal: J Neurosci
Title: Neurexin-neuroligin adhesions capture surface-diffusing AMPA receptors through PSD-95 scaffolds.
Volume: 31
Issue: 38
Pages: 13500-15
Publication
First Author: Soler-Llavina GJ
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: The neurexin ligands, neuroligins and leucine-rich repeat transmembrane proteins, perform convergent and divergent synaptic functions in vivo.
Volume: 108
Issue: 40
Pages: 16502-9
Publication
First Author: Budreck EC
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Neuroligin-1 controls synaptic abundance of NMDA-type glutamate receptors through extracellular coupling.
Volume: 110
Issue: 2
Pages: 725-30
Publication
First Author: Hoy JL
Year: 2013
Journal: J Neurosci
Title: Neuroligin1 drives synaptic and behavioral maturation through intracellular interactions.
Volume: 33
Issue: 22
Pages: 9364-84
Publication  
First Author: Dang R
Year: 2018
Journal: Neuropharmacology
Title: Regulation of hippocampal long term depression by Neuroligin 1.
Volume: 143
Pages: 205-216
GXD Expression      
Probe: MGI:6450884
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450907
Age: embryonic day 18.5
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6450884
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450907
Age: embryonic day 18.5
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5502647
Age: embryonic day 15.5
Image: 4I,I'
Detected: true
Specimen Num: 4
GXD Expression
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271123
Pattern: Non-Uniform
Stage: TS23
Assay Id: MGI:5502647
Age: embryonic day 15.5
Image: 4J,J'
Note: Caudal expression was similar between wild type and mutant, but rostral expression levels were reduced in the cortical plate.
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1753628
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 A
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1778728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 A
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 E
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 A
Detected: true
Specimen Num: 3
GXD Expression
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5502647
Age: embryonic day 13.5
Image: 3B
Note: Expression was down-regulated in cortical progenitors in the ventricular zone.
Detected: true
Specimen Num: 2
GXD Expression
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5502647
Age: embryonic day 13.5
Image: 3C
Note: Expression was down-regulated in cortical progenitors in the ventricular zone.
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691021
Pattern: Regionally restricted
Stage: TS21
Assay Id: MGI:5502647
Age: embryonic day 13.5
Note: Expression was detected in dorsal telencephalon.
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 D
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3284528
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 A
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274323
Pattern: Not Specified
Stage: TS23
Assay Id: MGI:5484666
Age: embryonic day 15.0
Image: S3 Bc
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 B
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3274328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 C
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:5502781
Assay Type: RNA in situ
Annotation Date: 2013-08-26
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:5502647
Age: embryonic day 13.5
Image: 3A
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S3 Be
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:5484521
Assay Type: Immunohistochemistry
Annotation Date: 2013-05-10
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:5484666
Age: postnatal adult
Image: S5 A
Detected: true
Specimen Num: 3
Publication    
First Author: Strausberg R
Year: 2001
Journal: GenBank Submission
Title: Mus musculus, similar to neuroligin 1, clone MGC: 7622 IMAGE: 3494913, mRNA, complete cds
Pages: BC005523
Publication
First Author: Gibson JR
Year: 2009
Journal: J Neurosci
Title: Neuroligin-2 deletion selectively decreases inhibitory synaptic transmission originating from fast-spiking but not from somatostatin-positive interneurons.
Volume: 29
Issue: 44
Pages: 13883-97
Publication
First Author: Molumby MJ
Year: 2017
Journal: Cell Rep
Title: γ-Protocadherins Interact with Neuroligin-1 and Negatively Regulate Dendritic Spine Morphogenesis.
Volume: 18
Issue: 11
Pages: 2702-2714
Publication
First Author: Chubykin AA
Year: 2007
Journal: Neuron
Title: Activity-dependent validation of excitatory versus inhibitory synapses by neuroligin-1 versus neuroligin-2.
Volume: 54
Issue: 6
Pages: 919-31
Publication
First Author: Moretto E
Year: 2019
Journal: Cell Rep
Title: TSPAN5 Enriched Microdomains Provide a Platform for Dendritic Spine Maturation through Neuroligin-1 Clustering.
Volume: 29
Issue: 5
Pages: 1130-1146.e8
Publication
First Author: Pettem KL
Year: 2013
Journal: J Cell Biol
Title: Interaction between autism-linked MDGAs and neuroligins suppresses inhibitory synapse development.
Volume: 200
Issue: 3
Pages: 321-36
Publication  
First Author: Hill-Yardin EL
Year: 2015
Journal: Neurosci Lett
Title: Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.
Volume: 589
Pages: 57-61
Publication
First Author: Baudouin SJ
Year: 2012
Journal: Science
Title: Shared synaptic pathophysiology in syndromic and nonsyndromic rodent models of autism.
Volume: 338
Issue: 6103
Pages: 128-32
Publication  
First Author: Chamma I
Year: 2016
Journal: Nat Commun
Title: Mapping the dynamics and nanoscale organization of synaptic adhesion proteins using monomeric streptavidin.
Volume: 7
Pages: 10773
Publication
First Author: Wittenmayer N
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Postsynaptic Neuroligin1 regulates presynaptic maturation.
Volume: 106
Issue: 32
Pages: 13564-9
Publication
First Author: Dean C
Year: 2003
Journal: Nat Neurosci
Title: Neurexin mediates the assembly of presynaptic terminals.
Volume: 6
Issue: 7
Pages: 708-16
Publication
First Author: Heine M
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Activity-independent and subunit-specific recruitment of functional AMPA receptors at neurexin/neuroligin contacts.
Volume: 105
Issue: 52
Pages: 20947-52
Publication
First Author: Chen SX
Year: 2010
Journal: Neuron
Title: Neurexin-neuroligin cell adhesion complexes contribute to synaptotropic dendritogenesis via growth stabilization mechanisms in vivo.
Volume: 67
Issue: 6
Pages: 967-83
Publication
First Author: Taniguchi H
Year: 2007
Journal: J Neurosci
Title: Silencing of neuroligin function by postsynaptic neurexins.
Volume: 27
Issue: 11
Pages: 2815-24
Publication  
First Author: Owczarek S
Year: 2015
Journal: Neural Plast
Title: Neurexin-Neuroligin Synaptic Complex Regulates Schizophrenia-Related DISC1/Kal-7/Rac1 "Signalosome".
Volume: 2015
Pages: 167308
Publication
First Author: Prange O
Year: 2004
Journal: Proc Natl Acad Sci U S A
Title: A balance between excitatory and inhibitory synapses is controlled by PSD-95 and neuroligin.
Volume: 101
Issue: 38
Pages: 13915-20
Publication
First Author: Bemben MA
Year: 2014
Journal: Nat Neurosci
Title: CaMKII phosphorylation of neuroligin-1 regulates excitatory synapses.
Volume: 17
Issue: 1
Pages: 56-64
Publication
First Author: Graf ER
Year: 2004
Journal: Cell
Title: Neurexins induce differentiation of GABA and glutamate postsynaptic specializations via neuroligins.
Volume: 119
Issue: 7
Pages: 1013-26
Publication
First Author: Varoqueaux F
Year: 2006
Journal: Neuron
Title: Neuroligins determine synapse maturation and function.
Volume: 51
Issue: 6
Pages: 741-54