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Search results 1 to 100 out of 247 for Nlgn3

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
key_1584457 | Nlgn3
Type: gene
Organism: Not Specified
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Gene
54413 | NLGN3
Type: gene
Organism: human
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Gene
100329188 | nlgn3
Type: gene
Organism: frog, western clawed
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Gene
171297 | Nlgn3
Type: gene
Organism: rat
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Gene
473660 | NLGN3
Type: gene
Organism: chimpanzee
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Gene
491947 | NLGN3
Type: gene
Organism: dog, domestic
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Gene
511251 | NLGN3
Type: gene
Organism: cattle
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Gene
770104 | NLGN3
Type: gene
Organism: chicken
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Gene
574216 | NLGN3
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR030024 | NLGN3
Type: Family
Description: Neuroligin-3 (NLGN3) belongs to the neuroligins (NLGNs) family, whose members interact with the neurexin family members and are involved in the modulation of synaptic transmission []. NLGN3 is a neuronal adhesion protein at both inhibitory GABAergic synapses and excitatory (glutamatergic) synapses []. Mutations in neuroligin 3 genes have been found in autism [].
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Protein Coding Gene
MGI:2444609 | Nlgn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17897391 | J:127247
First Author: Budreck EC
Year: 2007
Journal: Eur J Neurosci
Title: Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.
Volume: 26
Issue: 7
Pages: 1738-48
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Publication
36810932 | J:335132
 
First Author: Oleari R
Year: 2023
Journal: Dis Model Mech
Title: Autism-linked NLGN3 is a key regulator of gonadotropin-releasing hormone deficiency.
Volume: 16
Issue: 3
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Publication
24860089 | J:244384
First Author: Samarelli AV
Year: 2014
Journal: J Biol Chem
Title: Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
Volume: 289
Issue: 28
Pages: 19466-76
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Publication
25149987 | -
First Author: Maćkowiak M
Year: 2014
Journal: Pharmacol Rep
Title: Neuroligins, synapse balance and neuropsychiatric disorders.
Volume: 66
Issue: 5
Pages: 830-5
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Protein
Q8BYM5
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
B2RWZ9
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
A2AGI2
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: false
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Protein
A0A5S9EES2
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
A0A5S9EER5
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
Q69ZI4
Organism: Mus musculus/domesticus
Length: 876  
Fragment?: true
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Protein
A2AGI3
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
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Protein
A0A5S9EF37
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
Q924X0
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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Protein
A2AGI0
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: true
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Publication
35704570 | J:326980
First Author: Han Y
Year: 2022
Journal: Sci Adv
Title: Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses.
Volume: 8
Issue: 24
Pages: eabo4173
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Publication
36582822 | J:347513
First Author: Sgritta M
Year: 2023
Journal: iScience
Title: Impaired synaptic plasticity in an animal model of autism exhibiting early hippocampal GABAergic-BDNF/TrkB signaling alterations.
Volume: 26
Issue: 1
Pages: 105728
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Publication
33758193 | J:303834
First Author: Yoshida T
Year: 2021
Journal: Nat Commun
Title: Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Volume: 12
Issue: 1
Pages: 1848
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Publication
35992071 | J:336976
First Author: Ramirez MA
Year: 2022
Journal: iScience
Title: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3.
Volume: 25
Issue: 8
Pages: 104803
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Publication
28067903 | J:239827
First Author: Polepalli JS
Year: 2017
Journal: Nat Neurosci
Title: Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network.
Volume: 20
Issue: 2
Pages: 219-229
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Publication
31827744 | J:291965
 
First Author: Norris RHC
Year: 2019
Journal: Mol Autism
Title: Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference.
Volume: 10
Pages: 42
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Publication
37509099 | J:339158
 
First Author: Herath M
Year: 2023
Journal: Biomolecules
Title: Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal-Glial Synapses and Reduced Expression in Nlgn3(R451C) Mice.
Volume: 13
Issue: 7
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Publication
32381505 | J:296043
First Author: Uchigashima M
Year: 2020
Journal: J Biol Chem
Title: Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus.
Volume: 295
Issue: 25
Pages: 8589-8595
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Publication
28959975 | J:252846
First Author: Venkatesh HS
Year: 2017
Journal: Nature
Title: Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
Volume: 549
Issue: 7673
Pages: 533-537
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Publication
28795135 | J:255345
 
First Author: Kalbassi S
Year: 2017
Journal: eNeuro
Title: Male and Female Mice Lacking Neuroligin-3 Modify the Behavior of Their Wild-Type Littermates.
Volume: 4
Issue: 4
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Publication
33355091 | J:305288
   
First Author: Uchigashima M
Year: 2020
Journal: Elife
Title: Specific Neuroligin3-αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus.
Volume: 9
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Publication
26469287 | J:244467
First Author: Speed HE
Year: 2015
Journal: PLoS One
Title: Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling.
Volume: 10
Issue: 10
Pages: e0140638
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Publication
25592157 | J:219730
 
First Author: Hill-Yardin EL
Year: 2015
Journal: Neurosci Lett
Title: Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.
Volume: 589
Pages: 57-61
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Publication
28607166 | J:243282
First Author: Chanda S
Year: 2017
Journal: J Neurosci
Title: Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.
Volume: 37
Issue: 29
Pages: 6816-6836
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Publication
27217145 | J:326179
First Author: Jiang M
Year: 2017
Journal: Mol Psychiatry
Title: Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.
Volume: 22
Issue: 3
Pages: 375-383
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Publication
32327975 | J:290849
 
First Author: Sharna SS
Year: 2020
Journal: Front Cell Neurosci
Title: Altered Caecal Neuroimmune Interactions in the Neuroligin-3R451C Mouse Model of Autism.
Volume: 14
Pages: 85
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Publication
32760004 | J:294729
First Author: Hörnberg H
Year: 2020
Journal: Nature
Title: Rescue of oxytocin response and social behaviour in a mouse model of autism.
Volume: 584
Issue: 7820
Pages: 252-256
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Publication
30056576 | J:272678
     
First Author: Chmielewska JJ
Year: 2018
Journal: Mol Neurobiol
Title: Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
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Publication
34040258 | J:308741
First Author: Pan Y
Year: 2021
Journal: Nature
Title: NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
Volume: 594
Issue: 7862
Pages: 277-282
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Publication
26291161 | J:227671
First Author: Zhang B
Year: 2015
Journal: Neuron
Title: Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.
Volume: 87
Issue: 4
Pages: 781-96
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Publication
29100073 | J:252787
First Author: Südhof TC
Year: 2017
Journal: Cell
Title: Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Volume: 171
Issue: 4
Pages: 745-769
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Publication
30201312 | J:268578
 
First Author: Trobiani L
Year: 2018
Journal: Neurobiol Dis
Title: UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism.
Volume: 120
Pages: 139-150
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Publication
27581450 | J:235211
First Author: Zhang B
Year: 2016
Journal: J Neurosci
Title: Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.
Volume: 36
Issue: 35
Pages: 9070-83
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Publication
37865312 | J:343246
First Author: Benner O
Year: 2023
Journal: J Biol Chem
Title: Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.
Volume: 299
Issue: 12
Pages: 105361
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Publication
29724786 | J:264052
First Author: Zhang B
Year: 2018
Journal: J Exp Med
Title: Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Volume: 215
Issue: 6
Pages: 1543-1553
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Publication
24995986 | J:214636
First Author: Rothwell PE
Year: 2014
Journal: Cell
Title: Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.
Volume: 158
Issue: 1
Pages: 198-212
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Publication
27725662 | J:260025
First Author: Zhang B
Year: 2017
Journal: Mol Psychiatry
Title: Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.
Volume: 22
Issue: 10
Pages: 1483-1491
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Publication
34616037 | J:326180
First Author: Wu X
Year: 2021
Journal: Nature
Title: 5-HT modulation of a medial septal circuit tunes social memory stability.
Volume: 599
Issue: 7883
Pages: 96-101
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Publication
30871858 | J:276060
First Author: Wu X
Year: 2019
Journal: Neuron
Title: Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.
Volume: 102
Issue: 3
Pages: 621-635.e3
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Publication
32973045 | J:296694
First Author: Gan KJ
Year: 2020
Journal: J Neurosci
Title: SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.
Volume: 40
Issue: 42
Pages: 8088-8102
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Publication
34919427 | J:317210
First Author: Wang CY
Year: 2021
Journal: Sci Adv
Title: Molecular self-avoidance in synaptic neurexin complexes.
Volume: 7
Issue: 51
Pages: eabk1924
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Protein Coding Gene
MGP_CAROLIEiJ_G0033285 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031823 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034449 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19243448 | J:151116
First Author: Radyushkin K
Year: 2009
Journal: Genes Brain Behav
Title: Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit.
Volume: 8
Issue: 4
Pages: 416-25
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Publication
23583622 | J:197899
First Author: Földy C
Year: 2013
Journal: Neuron
Title: Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling.
Volume: 78
Issue: 3
Pages: 498-509
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Publication
22633921 | J:190481
First Author: Karvat G
Year: 2012
Journal: Behav Brain Res
Title: Systematic autistic-like behavioral phenotyping of 4 mouse strains using a novel wheel-running assay.
Volume: 233
Issue: 2
Pages: 405-14
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Publication
25144834 | J:274559
 
First Author: Isshiki M
Year: 2014
Journal: Nat Commun
Title: Enhanced synapse remodelling as a common phenotype in mouse models of autism.
Volume: 5
Pages: 4742
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Publication
32879325 | J:296407
First Author: Matta SM
Year: 2020
Journal: Sci Rep
Title: An altered glial phenotype in the NL3R451C mouse model of autism.
Volume: 10
Issue: 1
Pages: 14492
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Publication
30123111 | J:276309
 
First Author: Hosie S
Year: 2018
Journal: Front Cell Neurosci
Title: Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3R451C Mouse Model of Autism.
Volume: 12
Pages: 234
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Publication
37542090 | J:341249
First Author: Lee CYQ
Year: 2023
Journal: Sci Rep
Title: Impaired cecal motility and secretion alongside expansion of gut-associated lymphoid tissue in the Nlgn3(R451C) mouse model of autism.
Volume: 13
Issue: 1
Pages: 12687
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Publication
21808020 | J:175606
First Author: Etherton M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.
Volume: 108
Issue: 33
Pages: 13764-9
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Publication
34085373 | J:341332
First Author: Burrows EL
Year: 2022
Journal: Genes Brain Behav
Title: Mice with an autism-associated R451C mutation in neuroligin-3 show a cautious but accurate response style in touchscreen attention tasks.
Volume: 21
Issue: 1
Pages: e12757
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Publication
25347860 | J:228854
 
First Author: Cellot G
Year: 2014
Journal: Physiol Rep
Title: Reduced inhibitory gate in the barrel cortex of Neuroligin3R451C knock-in mice, an animal model of autism spectrum disorders.
Volume: 2
Issue: 7
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Publication
28255463 | J:271728
 
First Author: Burrows EL
Year: 2017
Journal: Neural Plast
Title: Social Isolation Alters Social and Mating Behavior in the R451C Neuroligin Mouse Model of Autism.
Volume: 2017
Pages: 8361290
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Publication
25299583 | J:223567
First Author: Kumar M
Year: 2014
Journal: PLoS One
Title: High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder.
Volume: 9
Issue: 10
Pages: e109872
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Publication
19360662 | J:167116
First Author: Chadman KK
Year: 2008
Journal: Autism Res
Title: Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.
Volume: 1
Issue: 3
Pages: 147-58
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Publication
21642956 | J:184114
First Author: Etherton MR
Year: 2011
Journal: EMBO J
Title: An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
Volume: 30
Issue: 14
Pages: 2908-19
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Publication
25778475 | J:323963
First Author: Chanda S
Year: 2016
Journal: Mol Psychiatry
Title: Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking.
Volume: 21
Issue: 2
Pages: 169-77
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Publication
31379628 | J:281801
 
First Author: Modi B
Year: 2019
Journal: Front Psychiatry
Title: Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism.
Volume: 10
Pages: 513
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Eye
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3759617
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6450888
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450910
Age: embryonic day 18.5
Specimen Label: wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6450888
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450910
Age: embryonic day 18.5
Specimen Label: knock-out
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (1)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (2)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (3)
Detected: true
Specimen Num: 3
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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