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Search results 1 to 100 out of 244 for Nlgn3

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
key_1584457 | Nlgn3
Type: gene
Organism: Not Specified
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Gene
54413 | NLGN3
Type: gene
Organism: human
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Gene
491947 | NLGN3
Type: gene
Organism: dog, domestic
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Gene
511251 | NLGN3
Type: gene
Organism: cattle
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Gene
770104 | NLGN3
Type: gene
Organism: chicken
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Gene
574216 | NLGN3
Type: gene
Organism: macaque, rhesus
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Gene
100329188 | nlgn3
Type: gene
Organism: frog, western clawed
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Gene
171297 | Nlgn3
Type: gene
Organism: rat
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Gene
473660 | NLGN3
Type: gene
Organism: chimpanzee
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Protein Domain
IPR030024 | NLGN3
Type: Family
Description: Neuroligin-3 (NLGN3) belongs to the neuroligins (NLGNs) family, whose members interact with the neurexin family members and are involved in the modulation of synaptic transmission []. NLGN3 is a neuronal adhesion protein at both inhibitory GABAergic synapses and excitatory (glutamatergic) synapses []. Mutations in neuroligin 3 genes have been found in autism [].
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Protein Coding Gene
MGI:2444609 | Nlgn3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
17897391 | J:127247
First Author: Budreck EC
Year: 2007
Journal: Eur J Neurosci
Title: Neuroligin-3 is a neuronal adhesion protein at GABAergic and glutamatergic synapses.
Volume: 26
Issue: 7
Pages: 1738-48
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Publication
36810932 | J:335132
 
First Author: Oleari R
Year: 2023
Journal: Dis Model Mech
Title: Autism-linked NLGN3 is a key regulator of gonadotropin-releasing hormone deficiency.
Volume: 16
Issue: 3
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Publication
24860089 | J:244384
First Author: Samarelli AV
Year: 2014
Journal: J Biol Chem
Title: Neuroligin 1 induces blood vessel maturation by cooperating with the α6 integrin.
Volume: 289
Issue: 28
Pages: 19466-76
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Publication
25149987 | -
First Author: Maćkowiak M
Year: 2014
Journal: Pharmacol Rep
Title: Neuroligins, synapse balance and neuropsychiatric disorders.
Volume: 66
Issue: 5
Pages: 830-5
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Protein
Q8BYM5
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
B2RWZ9
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
A2AGI2
Organism: Mus musculus/domesticus
Length: 845  
Fragment?: false
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Protein
A0A5S9EES2
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
A0A5S9EER5
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
Q69ZI4
Organism: Mus musculus/domesticus
Length: 876  
Fragment?: true
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Protein
A2AGI3
Organism: Mus musculus/domesticus
Length: 711  
Fragment?: false
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Protein
A0A5S9EF37
Organism: Mus musculus/domesticus
Length: 825  
Fragment?: false
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Protein
Q924X0
Organism: Mus musculus/domesticus
Length: 144  
Fragment?: true
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Protein
A2AGI0
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: true
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Publication
35704570 | J:326980
First Author: Han Y
Year: 2022
Journal: Sci Adv
Title: Neuroligin-3 confines AMPA receptors into nanoclusters, thereby controlling synaptic strength at the calyx of Held synapses.
Volume: 8
Issue: 24
Pages: eabo4173
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Publication
33758193 | J:303834
First Author: Yoshida T
Year: 2021
Journal: Nat Commun
Title: Canonical versus non-canonical transsynaptic signaling of neuroligin 3 tunes development of sociality in mice.
Volume: 12
Issue: 1
Pages: 1848
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Publication
35992071 | J:336976
First Author: Ramirez MA
Year: 2022
Journal: iScience
Title: Cochlear ribbon synapse maturation requires Nlgn1 and Nlgn3.
Volume: 25
Issue: 8
Pages: 104803
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Publication
28067903 | J:239827
First Author: Polepalli JS
Year: 2017
Journal: Nat Neurosci
Title: Modulation of excitation on parvalbumin interneurons by neuroligin-3 regulates the hippocampal network.
Volume: 20
Issue: 2
Pages: 219-229
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Publication
31827744 | J:291965
 
First Author: Norris RHC
Year: 2019
Journal: Mol Autism
Title: Mutations in neuroligin-3 in male mice impact behavioral flexibility but not relational memory in a touchscreen test of visual transitive inference.
Volume: 10
Pages: 42
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Publication
32381505 | J:296043
First Author: Uchigashima M
Year: 2020
Journal: J Biol Chem
Title: Neuroligin3 splice isoforms shape inhibitory synaptic function in the mouse hippocampus.
Volume: 295
Issue: 25
Pages: 8589-8595
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Publication
37509099 | J:339158
 
First Author: Herath M
Year: 2023
Journal: Biomolecules
Title: Quantitative Spatial Analysis of Neuroligin-3 mRNA Expression in the Enteric Nervous System Reveals a Potential Role in Neuronal-Glial Synapses and Reduced Expression in Nlgn3(R451C) Mice.
Volume: 13
Issue: 7
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Publication
28959975 | J:252846
First Author: Venkatesh HS
Year: 2017
Journal: Nature
Title: Targeting neuronal activity-regulated neuroligin-3 dependency in high-grade glioma.
Volume: 549
Issue: 7673
Pages: 533-537
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Publication
33355091 | J:305288
   
First Author: Uchigashima M
Year: 2020
Journal: Elife
Title: Specific Neuroligin3-αNeurexin1 signaling regulates GABAergic synaptic function in mouse hippocampus.
Volume: 9
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Publication
28795135 | J:255345
 
First Author: Kalbassi S
Year: 2017
Journal: eNeuro
Title: Male and Female Mice Lacking Neuroligin-3 Modify the Behavior of Their Wild-Type Littermates.
Volume: 4
Issue: 4
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Publication
26469287 | J:244467
First Author: Speed HE
Year: 2015
Journal: PLoS One
Title: Increased Cortical Inhibition in Autism-Linked Neuroligin-3R451C Mice Is Due in Part to Loss of Endocannabinoid Signaling.
Volume: 10
Issue: 10
Pages: e0140638
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Publication
25592157 | J:219730
 
First Author: Hill-Yardin EL
Year: 2015
Journal: Neurosci Lett
Title: Reduced susceptibility to induced seizures in the Neuroligin-3(R451C) mouse model of autism.
Volume: 589
Pages: 57-61
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Publication
27217145 | J:326179
First Author: Jiang M
Year: 2017
Journal: Mol Psychiatry
Title: Conditional ablation of neuroligin-1 in CA1 pyramidal neurons blocks LTP by a cell-autonomous NMDA receptor-independent mechanism.
Volume: 22
Issue: 3
Pages: 375-383
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Publication
28607166 | J:243282
First Author: Chanda S
Year: 2017
Journal: J Neurosci
Title: Unique versus Redundant Functions of Neuroligin Genes in Shaping Excitatory and Inhibitory Synapse Properties.
Volume: 37
Issue: 29
Pages: 6816-6836
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Publication
32327975 | J:290849
 
First Author: Sharna SS
Year: 2020
Journal: Front Cell Neurosci
Title: Altered Caecal Neuroimmune Interactions in the Neuroligin-3R451C Mouse Model of Autism.
Volume: 14
Pages: 85
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Publication
30056576 | J:272678
     
First Author: Chmielewska JJ
Year: 2018
Journal: Mol Neurobiol
Title: Neuroligin 1, 2, and 3 Regulation at the Synapse: FMRP-Dependent Translation and Activity-Induced Proteolytic Cleavage.
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Publication
32760004 | J:294729
First Author: Hörnberg H
Year: 2020
Journal: Nature
Title: Rescue of oxytocin response and social behaviour in a mouse model of autism.
Volume: 584
Issue: 7820
Pages: 252-256
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Publication
34040258 | J:308741
First Author: Pan Y
Year: 2021
Journal: Nature
Title: NF1 mutation drives neuronal activity-dependent initiation of optic glioma.
Volume: 594
Issue: 7862
Pages: 277-282
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Publication
26291161 | J:227671
First Author: Zhang B
Year: 2015
Journal: Neuron
Title: Neuroligins Sculpt Cerebellar Purkinje-Cell Circuits by Differential Control of Distinct Classes of Synapses.
Volume: 87
Issue: 4
Pages: 781-96
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Publication
29100073 | J:252787
First Author: Südhof TC
Year: 2017
Journal: Cell
Title: Synaptic Neurexin Complexes: A Molecular Code for the Logic of Neural Circuits.
Volume: 171
Issue: 4
Pages: 745-769
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Publication
30201312 | J:268578
 
First Author: Trobiani L
Year: 2018
Journal: Neurobiol Dis
Title: UPR activation specifically modulates glutamate neurotransmission in the cerebellum of a mouse model of autism.
Volume: 120
Pages: 139-150
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Publication
27581450 | J:235211
First Author: Zhang B
Year: 2016
Journal: J Neurosci
Title: Neuroligins Are Selectively Essential for NMDAR Signaling in Cerebellar Stellate Interneurons.
Volume: 36
Issue: 35
Pages: 9070-83
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Publication
37865312 | J:343246
First Author: Benner O
Year: 2023
Journal: J Biol Chem
Title: Multiple N-linked glycosylation sites critically modulate the synaptic abundance of neuroligin isoforms.
Volume: 299
Issue: 12
Pages: 105361
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Publication
29724786 | J:264052
First Author: Zhang B
Year: 2018
Journal: J Exp Med
Title: Autism-associated neuroligin-4 mutation selectively impairs glycinergic synaptic transmission in mouse brainstem synapses.
Volume: 215
Issue: 6
Pages: 1543-1553
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Publication
24995986 | J:214636
First Author: Rothwell PE
Year: 2014
Journal: Cell
Title: Autism-associated neuroligin-3 mutations commonly impair striatal circuits to boost repetitive behaviors.
Volume: 158
Issue: 1
Pages: 198-212
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Publication
34616037 | J:326180
First Author: Wu X
Year: 2021
Journal: Nature
Title: 5-HT modulation of a medial septal circuit tunes social memory stability.
Volume: 599
Issue: 7883
Pages: 96-101
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Publication
27725662 | J:260025
First Author: Zhang B
Year: 2017
Journal: Mol Psychiatry
Title: Developmental plasticity shapes synaptic phenotypes of autism-associated neuroligin-3 mutations in the calyx of Held.
Volume: 22
Issue: 10
Pages: 1483-1491
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Publication
30871858 | J:276060
First Author: Wu X
Year: 2019
Journal: Neuron
Title: Neuroligin-1 Signaling Controls LTP and NMDA Receptors by Distinct Molecular Pathways.
Volume: 102
Issue: 3
Pages: 621-635.e3
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Publication
32973045 | J:296694
First Author: Gan KJ
Year: 2020
Journal: J Neurosci
Title: SPARCL1 Promotes Excitatory But Not Inhibitory Synapse Formation and Function Independent of Neurexins and Neuroligins.
Volume: 40
Issue: 42
Pages: 8088-8102
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Publication
34919427 | J:317210
First Author: Wang CY
Year: 2021
Journal: Sci Adv
Title: Molecular self-avoidance in synaptic neurexin complexes.
Volume: 7
Issue: 51
Pages: eabk1924
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Protein Coding Gene
MGP_CAROLIEiJ_G0033285 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035943 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035926 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035635 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2444609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036455 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034922 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035610 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035764 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036482 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034621 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031823 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034449 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19243448 | J:151116
First Author: Radyushkin K
Year: 2009
Journal: Genes Brain Behav
Title: Neuroligin-3-deficient mice: model of a monogenic heritable form of autism with an olfactory deficit.
Volume: 8
Issue: 4
Pages: 416-25
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Publication
25144834 | J:274559
 
First Author: Isshiki M
Year: 2014
Journal: Nat Commun
Title: Enhanced synapse remodelling as a common phenotype in mouse models of autism.
Volume: 5
Pages: 4742
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Publication
31379628 | J:281801
 
First Author: Modi B
Year: 2019
Journal: Front Psychiatry
Title: Possible Implication of the CA2 Hippocampal Circuit in Social Cognition Deficits Observed in the Neuroligin 3 Knock-Out Mouse, a Non-Syndromic Animal Model of Autism.
Volume: 10
Pages: 513
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Publication
19360662 | J:167116
First Author: Chadman KK
Year: 2008
Journal: Autism Res
Title: Minimal aberrant behavioral phenotypes of neuroligin-3 R451C knockin mice.
Volume: 1
Issue: 3
Pages: 147-58
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Publication
21642956 | J:184114
First Author: Etherton MR
Year: 2011
Journal: EMBO J
Title: An autism-associated point mutation in the neuroligin cytoplasmic tail selectively impairs AMPA receptor-mediated synaptic transmission in hippocampus.
Volume: 30
Issue: 14
Pages: 2908-19
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Publication
25778475 | J:323963
First Author: Chanda S
Year: 2016
Journal: Mol Psychiatry
Title: Pathogenic mechanism of an autism-associated neuroligin mutation involves altered AMPA-receptor trafficking.
Volume: 21
Issue: 2
Pages: 169-77
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Publication
23583622 | J:197899
First Author: Földy C
Year: 2013
Journal: Neuron
Title: Autism-associated neuroligin-3 mutations commonly disrupt tonic endocannabinoid signaling.
Volume: 78
Issue: 3
Pages: 498-509
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Publication
30123111 | J:276309
 
First Author: Hosie S
Year: 2018
Journal: Front Cell Neurosci
Title: Altered Amygdala Excitation and CB1 Receptor Modulation of Aggressive Behavior in the Neuroligin-3R451C Mouse Model of Autism.
Volume: 12
Pages: 234
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Publication
22633921 | J:190481
First Author: Karvat G
Year: 2012
Journal: Behav Brain Res
Title: Systematic autistic-like behavioral phenotyping of 4 mouse strains using a novel wheel-running assay.
Volume: 233
Issue: 2
Pages: 405-14
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Publication
25299583 | J:223567
First Author: Kumar M
Year: 2014
Journal: PLoS One
Title: High resolution magnetic resonance imaging for characterization of the neuroligin-3 knock-in mouse model associated with autism spectrum disorder.
Volume: 9
Issue: 10
Pages: e109872
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Publication
25347860 | J:228854
 
First Author: Cellot G
Year: 2014
Journal: Physiol Rep
Title: Reduced inhibitory gate in the barrel cortex of Neuroligin3R451C knock-in mice, an animal model of autism spectrum disorders.
Volume: 2
Issue: 7
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Publication
28255463 | J:271728
 
First Author: Burrows EL
Year: 2017
Journal: Neural Plast
Title: Social Isolation Alters Social and Mating Behavior in the R451C Neuroligin Mouse Model of Autism.
Volume: 2017
Pages: 8361290
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Publication
21808020 | J:175606
First Author: Etherton M
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Autism-linked neuroligin-3 R451C mutation differentially alters hippocampal and cortical synaptic function.
Volume: 108
Issue: 33
Pages: 13764-9
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Publication
37542090 | J:341249
First Author: Lee CYQ
Year: 2023
Journal: Sci Rep
Title: Impaired cecal motility and secretion alongside expansion of gut-associated lymphoid tissue in the Nlgn3(R451C) mouse model of autism.
Volume: 13
Issue: 1
Pages: 12687
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Publication
32879325 | J:296407
First Author: Matta SM
Year: 2020
Journal: Sci Rep
Title: An altered glial phenotype in the NL3R451C mouse model of autism.
Volume: 10
Issue: 1
Pages: 14492
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Publication
34085373 | J:341332
First Author: Burrows EL
Year: 2022
Journal: Genes Brain Behav
Title: Mice with an autism-associated R451C mutation in neuroligin-3 show a cautious but accurate response style in touchscreen attention tasks.
Volume: 21
Issue: 1
Pages: e12757
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Brain
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Eye
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:3759617
Age: postnatal adult
Specimen Label: Heart
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3759506
Assay Type: RT-PCR
Annotation Date: 2007-10-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603922
Stage: TS22
Assay Id: MGI:3759617
Age: embryonic day 14.5
Specimen Label: E14.5
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:6450888
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450910
Age: embryonic day 18.5
Specimen Label: wild type
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6450888
Assay Type: Western blot
Annotation Date: 2020-08-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3267826
Stage: TS26
Assay Id: MGI:6450910
Age: embryonic day 18.5
Specimen Label: knock-out
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (1)
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (2)
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21+/+ (3)
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7506557
Assay Type: Western blot
Annotation Date: 2023-07-12
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7506646
Age: postnatal day 4
Image: 4
Specimen Label: Igsf21-/- (1)
Detected: true
Specimen Num: 4
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