|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 351 for Nlrc4

<< First    < Previous  |  Next >    Last >>
0.035s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
58484 | NLRC4
Type: gene
Organism: human
•
•
•
•
•
Gene
733844 | nlrc4
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
119877189 | NLRC4
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
298784 | Nlrc4
Type: gene
Organism: rat
•
•
•
•
•
Gene
459135 | NLRC4
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
100302328 | NLRC4
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
512480 | NLRC4
Type: gene
Organism: cattle
•
•
•
•
•
Gene
706378 | NLRC4
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Domain
IPR042220 | NLRC4
Type: Family
Description: NLRC4 is a nucleotide binding/leucine-rich Repeat (NLR) protein and a inflammasome activator. It contains an N-terminal homotypic interaction domain, a central nucleotide binding domain, and a series of C-terminal LRRs. NLRC4 activates CASP1, the primary protease responsible for converting pro-IL-1beta to active, secreted IL-1beta. NLRC4 has been linked to autoinflammation diseases [].
•
•
•
•
•
Protein Coding Gene
MGI:3036243 | Nlrc4
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
29247997 | -
First Author: Duncan JA
Year: 2018
Journal: Immunol Rev
Title: The NLRC4 Inflammasome.
Volume: 281
Issue: 1
Pages: 115-123
•
•
•
•
•
Publication
25385754 | J:219652
First Author: Kitamura A
Year: 2014
Journal: J Exp Med
Title: An inherited mutation in NLRC4 causes autoinflammation in human and mice.
Volume: 211
Issue: 12
Pages: 2385-96
•
•
•
•
•
Publication
27139490 | J:234785
First Author: Qu Y
Year: 2016
Journal: J Exp Med
Title: NLRP3 recruitment by NLRC4 during Salmonella infection.
Volume: 213
Issue: 6
Pages: 877-85
•
•
•
•
•
Publication
23765277 | J:245334
First Author: Hu Z
Year: 2013
Journal: Science
Title: Crystal structure of NLRC4 reveals its autoinhibition mechanism.
Volume: 341
Issue: 6142
Pages: 172-5
•
•
•
•
•
Protein
A0A3B2W7U6
Organism: Mus musculus/domesticus
Length: 116  
Fragment?: false
•
•
•
•
•
Publication
27708283 | J:242358
 
First Author: Kolb R
Year: 2016
Journal: Nat Commun
Title: Obesity-associated NLRC4 inflammasome activation drives breast cancer progression.
Volume: 7
Pages: 13007
•
•
•
•
•
Publication
22885697 | J:189256
First Author: Qu Y
Year: 2012
Journal: Nature
Title: Phosphorylation of NLRC4 is critical for inflammasome activation.
Volume: 490
Issue: 7421
Pages: 539-42
•
•
•
•
•
Protein
Q3UP24
Organism: Mus musculus/domesticus
Length: 1024  
Fragment?: false
•
•
•
•
•
Protein
A0A3Q4EGE7
Organism: Mus musculus/domesticus
Length: 1036  
Fragment?: false
•
•
•
•
•
Publication
29576451 | J:262477
First Author: Karki R
Year: 2018
Journal: Cell
Title: IRF8 Regulates Transcription of Naips for NLRC4 Inflammasome Activation.
Volume: 173
Issue: 4
Pages: 920-933.e13
•
•
•
•
•
Publication
21282416 | J:170102
First Author: Lightfield KL
Year: 2011
Journal: Infect Immun
Title: Differential requirements for NAIP5 in activation of the NLRC4 inflammasome.
Volume: 79
Issue: 4
Pages: 1606-14
•
•
•
•
•
Publication
27617861 | J:237381
First Author: Janowski AM
Year: 2016
Journal: J Clin Invest
Title: NLRC4 suppresses melanoma tumor progression independently of inflammasome activation.
Volume: 126
Issue: 10
Pages: 3917-3928
•
•
•
•
•
Publication
25605939 | J:217657
First Author: Matusiak M
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Flagellin-induced NLRC4 phosphorylation primes the inflammasome for activation by NAIP5.
Volume: 112
Issue: 5
Pages: 1541-6
•
•
•
•
•
Publication
34383985 | J:310451
First Author: Alippe Y
Year: 2021
Journal: FASEB J
Title: Actions of the NLRP3 and NLRC4 inflammasomes overlap in bone resorption.
Volume: 35
Issue: 9
Pages: e21837
•
•
•
•
•
Publication
35277504 | J:322890
First Author: Mohamed MF
Year: 2022
Journal: Nat Commun
Title: CrkII/Abl phosphorylation cascade is critical for NLRC4 inflammasome activity and is blocked by Pseudomonas aeruginosa ExoT.
Volume: 13
Issue: 1
Pages: 1295
•
•
•
•
•
Publication
24453428 | J:357940
 
First Author: DeSantis DA
Year: 2013
Journal: Mediators Inflamm
Title: Alcohol-induced liver injury is modulated by Nlrp3 and Nlrc4 inflammasomes in mice.
Volume: 2013
Pages: 751374
•
•
•
•
•
Publication
35833522 | J:360476
First Author: Chen X
Year: 2022
Journal: EMBO Rep
Title: Vitamin D receptor enhances NLRC4 inflammasome activation by promoting NAIPs-NLRC4 association.
Volume: 23
Issue: 9
Pages: e54611
•
•
•
•
•
Publication
21918512 | J:177040
First Author: Zhao Y
Year: 2011
Journal: Nature
Title: The NLRC4 inflammasome receptors for bacterial flagellin and type III secretion apparatus.
Volume: 477
Issue: 7366
Pages: 596-600
•
•
•
•
•
Publication
29491424 | J:262639
First Author: Lee BL
Year: 2018
Journal: Sci Rep
Title: ASC- and caspase-8-dependent apoptotic pathway diverges from the NLRC4 inflammasome in macrophages.
Volume: 8
Issue: 1
Pages: 3788
•
•
•
•
•
Publication
21072873 | J:174469
First Author: Vijay-Kumar M
Year: 2010
Journal: Eur J Immunol
Title: TLR5 or NLRC4 is necessary and sufficient for promotion of humoral immunity by flagellin.
Volume: 40
Issue: 12
Pages: 3528-34
•
•
•
•
•
Publication
32342103 | J:294930
 
First Author: Tenthorey JL
Year: 2020
Journal: J Exp Med
Title: NLRC4 inflammasome activation is NLRP3- and phosphorylation-independent during infection and does not protect from melanoma.
Volume: 217
Issue: 7
•
•
•
•
•
Publication
20603313 | J:163379
First Author: Broz P
Year: 2010
Journal: J Exp Med
Title: Redundant roles for inflammasome receptors NLRP3 and NLRC4 in host defense against Salmonella.
Volume: 207
Issue: 8
Pages: 1745-55
•
•
•
•
•
Publication
20713892 | J:163816
First Author: Malireddi RK
Year: 2010
Journal: J Immunol
Title: Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.
Volume: 185
Issue: 6
Pages: 3127-30
•
•
•
•
•
Publication
25775556 | J:220673
First Author: Denes A
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: AIM2 and NLRC4 inflammasomes contribute with ASC to acute brain injury independently of NLRP3.
Volume: 112
Issue: 13
Pages: 4050-5
•
•
•
•
•
Publication
20048047 | J:157768
First Author: Silveira TN
Year: 2010
Journal: Infect Immun
Title: Pore formation triggered by Legionella spp. is an Nlrc4 inflammasome-dependent host cell response that precedes pyroptosis.
Volume: 78
Issue: 3
Pages: 1403-13
•
•
•
•
•
Publication
33177235 | J:300067
First Author: Akhade AS
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: Type 1 interferon-dependent repression of NLRC4 and iPLA2 licenses down-regulation of Salmonella flagellin inside macrophages.
Volume: 117
Issue: 47
Pages: 29811-29822
•
•
•
•
•
Publication
22231517 | J:181212
First Author: Kupz A
Year: 2012
Journal: Nat Immunol
Title: NLRC4 inflammasomes in dendritic cells regulate noncognate effector function by memory CD8⁺ T cells.
Volume: 13
Issue: 2
Pages: 162-9
•
•
•
•
•
Publication
22174673 | J:183161
First Author: Tomalka J
Year: 2011
Journal: PLoS Pathog
Title: A novel role for the NLRC4 inflammasome in mucosal defenses against the fungal pathogen Candida albicans.
Volume: 7
Issue: 12
Pages: e1002379
•
•
•
•
•
Publication
22547706 | J:188721
First Author: Cai S
Year: 2012
Journal: J Immunol
Title: NLRC4 inflammasome-mediated production of IL-1β modulates mucosal immunity in the lung against gram-negative bacterial infection.
Volume: 188
Issue: 11
Pages: 5623-35
•
•
•
•
•
Publication
21687424 | J:177981
 
First Author: Pereira MS
Year: 2011
Journal: Front Microbiol
Title: The Nlrc4 Inflammasome Contributes to Restriction of Pulmonary Infection by Flagellated Legionella spp. that Trigger Pyroptosis.
Volume: 2
Pages: 33
•
•
•
•
•
Publication
24827856 | J:217355
First Author: Kupz A
Year: 2014
Journal: PLoS One
Title: In vivo IFN-γ secretion by NK cells in response to Salmonella typhimurium requires NLRC4 inflammasomes.
Volume: 9
Issue: 5
Pages: e97418
•
•
•
•
•
Publication
31038471 | J:289200
First Author: Hornick EE
Year: 2019
Journal: J Clin Invest
Title: Dendritic cell NLRC4 regulates influenza A virus-specific CD4 T cell responses through FasL expression.
Volume: 129
Issue: 7
Pages: 2888-2897
•
•
•
•
•
Publication
30279514 | J:295647
First Author: Paudel S
Year: 2019
Journal: Mucosal Immunol
Title: NLRC4 suppresses IL-17A-mediated neutrophil-dependent host defense through upregulation of IL-18 and induction of necroptosis during Gram-positive pneumonia.
Volume: 12
Issue: 1
Pages: 247-257
•
•
•
•
•
Publication
33333046 | J:305575
 
First Author: Yao K
Year: 2021
Journal: Exp Eye Res
Title: Involvement of the NLRC4 inflammasome in promoting retinal ganglion cell death in an acute glaucoma mouse model.
Volume: 203
Pages: 108388
•
•
•
•
•
Publication
28404595 | J:242007
First Author: Freeman L
Year: 2017
Journal: J Exp Med
Title: NLR members NLRC4 and NLRP3 mediate sterile inflammasome activation in microglia and astrocytes.
Volume: 214
Issue: 5
Pages: 1351-1370
•
•
•
•
•
Publication
34860583 | J:335284
First Author: Wang SB
Year: 2021
Journal: Sci Immunol
Title: DDX17 is an essential mediator of sterile NLRC4 inflammasome activation by retrotransposon RNAs.
Volume: 6
Issue: 66
Pages: eabi4493
•
•
•
•
•
Publication
34678072 | J:312930
First Author: Zhang P
Year: 2021
Journal: Sci Adv
Title: NLRC4 inflammasome-dependent cell death occurs by a complementary series of three death pathways and determines lethality in mice.
Volume: 7
Issue: 43
Pages: eabi9471
•
•
•
•
•
Publication
20133635 | J:157567
First Author: Miao EA
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Innate immune detection of the type III secretion apparatus through the NLRC4 inflammasome.
Volume: 107
Issue: 7
Pages: 3076-80
•
•
•
•
•
Publication
28961278 | J:246906
First Author: McClellan SA
Year: 2017
Journal: PLoS One
Title: NLRC4 regulates caspase-1 and IL-1beta production in a CD11blowLy6Glow population of cells required for resistance to Pseudomonas aeruginosa keratitis.
Volume: 12
Issue: 9
Pages: e0185718
•
•
•
•
•
Publication
24803432 | J:211051
First Author: Man SM
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Inflammasome activation causes dual recruitment of NLRC4 and NLRP3 to the same macromolecular complex.
Volume: 111
Issue: 20
Pages: 7403-8
•
•
•
•
•
Publication
24516390 | J:246374
First Author: Suzuki S
Year: 2014
Journal: PLoS Pathog
Title: Shigella type III secretion protein MxiI is recognized by Naip2 to induce Nlrc4 inflammasome activation independently of Pkcδ.
Volume: 10
Issue: 2
Pages: e1003926
•
•
•
•
•
Publication
21746921 | J:174533
First Author: Sauer JD
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Listeria monocytogenes engineered to activate the Nlrc4 inflammasome are severely attenuated and are poor inducers of protective immunity.
Volume: 108
Issue: 30
Pages: 12419-24
•
•
•
•
•
Publication
25959047 | J:224889
 
First Author: Ip WK
Year: 2015
Journal: Nat Commun
Title: Macrophages monitor tissue osmolarity and induce inflammatory response through NLRP3 and NLRC4 inflammasome activation.
Volume: 6
Pages: 6931
•
•
•
•
•
Publication
23024281 | J:190602
First Author: Karmakar M
Year: 2012
Journal: J Immunol
Title: Cutting edge: IL-1β processing during Pseudomonas aeruginosa infection is mediated by neutrophil serine proteases and is independent of NLRC4 and caspase-1.
Volume: 189
Issue: 9
Pages: 4231-5
•
•
•
•
•
Publication
22079982 | J:180406
First Author: Pereira MS
Year: 2011
Journal: J Immunol
Title: Activation of NLRC4 by flagellated bacteria triggers caspase-1-dependent and -independent responses to restrict Legionella pneumophila replication in macrophages and in vivo.
Volume: 187
Issue: 12
Pages: 6447-55
•
•
•
•
•
Publication
33178225 | J:336797
 
First Author: Sasaki Y
Year: 2020
Journal: Front Immunol
Title: Distinct Roles of IL-1β and IL-18 in NLRC4-Induced Autoinflammation.
Volume: 11
Pages: 591713
•
•
•
•
•
Publication
38460128 | J:346720
First Author: Gül E
Year: 2024
Journal: Cell Rep
Title: Salmonella T3SS-2 virulence enhances gut-luminal colonization by enabling chemotaxis-dependent exploitation of intestinal inflammation.
Volume: 43
Issue: 3
Pages: 113925
•
•
•
•
•
Publication
29146805 | J:277864
First Author: Tenthorey JL
Year: 2017
Journal: Science
Title: The structural basis of flagellin detection by NAIP5: A strategy to limit pathogen immune evasion.
Volume: 358
Issue: 6365
Pages: 888-893
•
•
•
•
•
Publication
26585513 | J:247416
First Author: Diebolder CA
Year: 2015
Journal: Structure
Title: Cryoelectron Tomography of the NAIP5/NLRC4 Inflammasome: Implications for NLR Activation.
Volume: 23
Issue: 12
Pages: 2349-57
•
•
•
•
•
Publication
26449475 | J:245327
First Author: Hu Z
Year: 2015
Journal: Science
Title: Structural and biochemical basis for induced self-propagation of NLRC4.
Volume: 350
Issue: 6259
Pages: 399-404
•
•
•
•
•
Publication
28684545 | J:248040
First Author: Fan LC
Year: 2017
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Macrolides protect against Pseudomonas aeruginosa infection via inhibition of inflammasomes.
Volume: 313
Issue: 4
Pages: L677-L686
•
•
•
•
•
Publication
36835212 | J:352287
 
First Author: Yang XM
Year: 2023
Journal: Int J Mol Sci
Title: Lethal Caspase-1/4-Dependent Injury Occurs in the First Minutes of Coronary Reperfusion and Requires Calpain Activity.
Volume: 24
Issue: 4
•
•
•
•
•
Publication
27706238 | J:256809
First Author: Yuan F
Year: 2016
Journal: PLoS One
Title: Involvement of the NLRC4-Inflammasome in Diabetic Nephropathy.
Volume: 11
Issue: 10
Pages: e0164135
•
•
•
•
•
Publication
22484733 | J:185371
First Author: Franchi L
Year: 2012
Journal: Nat Immunol
Title: NLRC4-driven production of IL-1β discriminates between pathogenic and commensal bacteria and promotes host intestinal defense.
Volume: 13
Issue: 5
Pages: 449-56
•
•
•
•
•
Publication
26449474 | J:245242
First Author: Zhang L
Year: 2015
Journal: Science
Title: Cryo-EM structure of the activated NAIP2-NLRC4 inflammasome reveals nucleated polymerization.
Volume: 350
Issue: 6259
Pages: 404-9
•
•
•
•
•
Publication
21118981 | J:167130
First Author: Hu B
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Inflammation-induced tumorigenesis in the colon is regulated by caspase-1 and NLRC4.
Volume: 107
Issue: 50
Pages: 21635-40
•
•
•
•
•
Publication
27114610 | J:233312
First Author: Zhao Y
Year: 2016
Journal: J Exp Med
Title: Genetic functions of the NAIP family of inflammasome receptors for bacterial ligands in mice.
Volume: 213
Issue: 5
Pages: 647-56
•
•
•
•
•
Publication
23478406 | J:197539
First Author: Cohen TS
Year: 2013
Journal: J Clin Invest
Title: Activation of inflammasome signaling mediates pathology of acute P. aeruginosa pneumonia.
Volume: 123
Issue: 4
Pages: 1630-7
•
•
•
•
•
Publication
23940371 | J:200910
First Author: Yang J
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Human NAIP and mouse NAIP1 recognize bacterial type III secretion needle protein for inflammasome activation.
Volume: 110
Issue: 35
Pages: 14408-13
•
•
•
•
•
Publication
26516283 | J:226609
First Author: Schieber AM
Year: 2015
Journal: Science
Title: Disease tolerance mediated by microbiome E. coli involves inflammasome and IGF-1 signaling.
Volume: 350
Issue: 6260
Pages: 558-63
•
•
•
•
•
Publication
29263322 | J:260047
First Author: Nichols RD
Year: 2017
Journal: Nat Commun
Title: NAIP/NLRC4 inflammasome activation in MRP8+ cells is sufficient to cause systemic inflammatory disease.
Volume: 8
Issue: 1
Pages: 2209
•
•
•
•
•
Publication
24123685 | J:206327
First Author: Man SM
Year: 2013
Journal: J Immunol
Title: Salmonella infection induces recruitment of Caspase-8 to the inflammasome to modulate IL-1β production.
Volume: 191
Issue: 10
Pages: 5239-46
•
•
•
•
•
Publication
38124741 | J:348226
 
First Author: Amaral MP
Year: 2023
Journal: Front Immunol
Title: NAIP/NLRC4 inflammasome participates in macrophage responses to Trypanosoma cruzi by a mechanism that relies on cathepsin-dependent caspase-1 cleavage.
Volume: 14
Pages: 1282856
•
•
•
•
•
Publication
26972847 | J:236557
 
First Author: Iannitti RG
Year: 2016
Journal: Nat Commun
Title: IL-1 receptor antagonist ameliorates inflammasome-dependent inflammation in murine and human cystic fibrosis.
Volume: 7
Pages: 10791
•
•
•
•
•
Publication
36417874 | J:332004
First Author: Oh C
Year: 2022
Journal: Cell Rep
Title: Neutrophil inflammasomes sense the subcellular delivery route of translocated bacterial effectors and toxins.
Volume: 41
Issue: 8
Pages: 111688
•
•
•
•
•
Publication
22461621 | J:185438
First Author: Liu Z
Year: 2012
Journal: J Biol Chem
Title: Role of inflammasomes in host defense against Citrobacter rodentium infection.
Volume: 287
Issue: 20
Pages: 16955-64
•
•
•
•
•
Publication
29262324 | J:254284
First Author: Van Opdenbosch N
Year: 2017
Journal: Cell Rep
Title: Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.
Volume: 21
Issue: 12
Pages: 3427-3444
•
•
•
•
•
Publication
37730693 | J:340803
First Author: Minns MS
Year: 2023
Journal: Nat Commun
Title: NLRP3 selectively drives IL-1β secretion by Pseudomonas aeruginosa infected neutrophils and regulates corneal disease severity.
Volume: 14
Issue: 1
Pages: 5832
•
•
•
•
•
Publication
30982580 | J:290395
First Author: Zhang T
Year: 2019
Journal: Biochem Biophys Res Commun
Title: NLRP3/ASC/Caspase-1 axis and serine protease activity are involved in neutrophil IL-1β processing during Streptococcus pneumoniae infection.
Volume: 513
Issue: 3
Pages: 675-680
•
•
•
•
•
Publication
30518876 | J:287455
First Author: Kolb R
Year: 2019
Journal: Oncogene
Title: Obesity-associated inflammation promotes angiogenesis and breast cancer via angiopoietin-like 4.
Volume: 38
Issue: 13
Pages: 2351-2363
•
•
•
•
•
Publication
27855208 | J:248105
First Author: Floyd M
Year: 2016
Journal: PLoS Pathog
Title: Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa.
Volume: 12
Issue: 11
Pages: e1005987
•
•
•
•
•
Publication
21057511 | J:167323
First Author: Miao EA
Year: 2010
Journal: Nat Immunol
Title: Caspase-1-induced pyroptosis is an innate immune effector mechanism against intracellular bacteria.
Volume: 11
Issue: 12
Pages: 1136-42
•
•
•
•
•
Publication
26572063 | J:253912
First Author: Maltez VI
Year: 2015
Journal: Immunity
Title: Inflammasomes Coordinate Pyroptosis and Natural Killer Cell Cytotoxicity to Clear Infection by a Ubiquitous Environmental Bacterium.
Volume: 43
Issue: 5
Pages: 987-97
•
•
•
•
•
Publication
33074100 | J:298673
   
First Author: Mitchell PS
Year: 2020
Journal: Elife
Title: NAIP-NLRC4-deficient mice are susceptible to shigellosis.
Volume: 9
•
•
•
•
•
Publication
19343209 | J:162695
First Author: Akhter A
Year: 2009
Journal: PLoS Pathog
Title: Caspase-7 activation by the Nlrc4/Ipaf inflammasome restricts Legionella pneumophila infection.
Volume: 5
Issue: 4
Pages: e1000361
•
•
•
•
•
Publication
22902502 | J:188134
First Author: von Moltke J
Year: 2012
Journal: Nature
Title: Rapid induction of inflammatory lipid mediators by the inflammasome in vivo.
Volume: 490
Issue: 7418
Pages: 107-11
•
•
•
•
•
Publication
28771586 | J:283562
First Author: Mascarenhas DPA
Year: 2017
Journal: PLoS Pathog
Title: Inhibition of caspase-1 or gasdermin-D enable caspase-8 activation in the Naip5/NLRC4/ASC inflammasome.
Volume: 13
Issue: 8
Pages: e1006502
•
•
•
•
•
Publication
20385749 | J:161241
First Author: Allen IC
Year: 2010
Journal: J Exp Med
Title: The NLRP3 inflammasome functions as a negative regulator of tumorigenesis during colitis-associated cancer.
Volume: 207
Issue: 5
Pages: 1045-56
•
•
•
•
•
Publication
24798340 | J:216031
First Author: Zhao C
Year: 2014
Journal: J Biol Chem
Title: Nuclear factor E2-related factor-2 (Nrf2) is required for NLRP3 and AIM2 inflammasome activation.
Volume: 289
Issue: 24
Pages: 17020-9
•
•
•
•
•
Publication
32760056 | J:294734
First Author: Xiao J
Year: 2020
Journal: PLoS Biol
Title: Radiation causes tissue damage by dysregulating inflammasome-gasdermin D signaling in both host and transplanted cells.
Volume: 18
Issue: 8
Pages: e3000807
•
•
•
•
•
Publication
21037094 | J:166140
First Author: McCoy AJ
Year: 2010
Journal: J Immunol
Title: Differential regulation of caspase-1 activation via NLRP3/NLRC4 inflammasomes mediated by aerolysin and type III secretion system during Aeromonas veronii infection.
Volume: 185
Issue: 11
Pages: 7077-84
•
•
•
•
•
Publication
29326099 | J:261562
First Author: Weiss ES
Year: 2018
Journal: Blood
Title: Interleukin-18 diagnostically distinguishes and pathogenically promotes human and murine macrophage activation syndrome.
Volume: 131
Issue: 13
Pages: 1442-1455
•
•
•
•
•
Publication
28410991 | J:255168
First Author: Rauch I
Year: 2017
Journal: Immunity
Title: NAIP-NLRC4 Inflammasomes Coordinate Intestinal Epithelial Cell Expulsion with Eicosanoid and IL-18 Release via Activation of Caspase-1 and -8.
Volume: 46
Issue: 4
Pages: 649-659
•
•
•
•
•
Publication
19696895 | J:162910
First Author: Shio MT
Year: 2009
Journal: PLoS Pathog
Title: Malarial hemozoin activates the NLRP3 inflammasome through Lyn and Syk kinases.
Volume: 5
Issue: 8
Pages: e1000559
•
•
•
•
•
Publication
24638169 | J:211688
First Author: Wynosky-Dolfi MA
Year: 2014
Journal: J Exp Med
Title: Oxidative metabolism enables Salmonella evasion of the NLRP3 inflammasome.
Volume: 211
Issue: 4
Pages: 653-68
•
•
•
•
•
Publication
29353059 | J:261112
First Author: Place DE
Year: 2018
Journal: Am J Pathol
Title: ASK Family Kinases Are Required for Optimal NLRP3 Inflammasome Priming.
Volume: 188
Issue: 4
Pages: 1021-1030
•
•
•
•
•
Publication
21874021 | J:176197
First Author: Kofoed EM
Year: 2011
Journal: Nature
Title: Innate immune recognition of bacterial ligands by NAIPs determines inflammasome specificity.
Volume: 477
Issue: 7366
Pages: 592-5
•
•
•
•
•
Publication
23460746 | J:194921
First Author: Gomes MT
Year: 2013
Journal: J Immunol
Title: Critical role of ASC inflammasomes and bacterial type IV secretion system in caspase-1 activation and host innate resistance to Brucella abortus infection.
Volume: 190
Issue: 7
Pages: 3629-38
•
•
•
•
•
Publication
22911706 | J:189888
First Author: Abdalla H
Year: 2012
Journal: PLoS One
Title: Mycobacterium tuberculosis infection of dendritic cells leads to partially caspase-1/11-independent IL-1β and IL-18 secretion but not to pyroptosis.
Volume: 7
Issue: 7
Pages: e40722
•
•
•
•
•
Publication
38055781 | J:355539
   
First Author: Abele TJ
Year: 2023
Journal: Elife
Title: Apoptotic signaling clears engineered Salmonella in an organ-specific manner.
Volume: 12
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom