Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Cui J |
Year: |
2010 |
Journal: |
Cell |
Title: |
NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways. |
Volume: |
141 |
Issue: |
3 |
Pages: |
483-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luan P |
Year: |
2018 |
Journal: |
FASEB J |
Title: |
NLRC5 deficiency ameliorates diabetic nephropathy through alleviating inflammation. |
Volume: |
32 |
Issue: |
2 |
Pages: |
1070-1084 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dang AT |
Year: |
2021 |
Journal: |
iScience |
Title: |
NLRC5 promotes transcription of BTN3A1-3 genes and Vγ9Vδ2 T cell-mediated killing. |
Volume: |
24 |
Issue: |
1 |
Pages: |
101900 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2022 |
Journal: |
J Periodontal Res |
Title: |
NLRC5 modulates bone metabolism and plays a role in periodontitis. |
Volume: |
57 |
Issue: |
4 |
Pages: |
891-903 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ludigs K |
Year: |
2016 |
Journal: |
Nat Commun |
Title: |
NLRC5 shields T lymphocytes from NK-cell-mediated elimination under inflammatory conditions. |
Volume: |
7 |
|
Pages: |
10554 |
|
•
•
•
•
•
|
Publication |
First Author: |
Luan P |
Year: |
2019 |
Journal: |
Nat Commun |
Title: |
NLRC5 inhibits neointima formation following vascular injury and directly interacts with PPARγ. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2882 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar H |
Year: |
2011 |
Journal: |
J Immunol |
Title: |
NLRC5 deficiency does not influence cytokine induction by virus and bacteria infections. |
Volume: |
186 |
Issue: |
2 |
Pages: |
994-1000 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chonwerawong M |
Year: |
2020 |
Journal: |
Gastroenterology |
Title: |
Innate Immune Molecule NLRC5 Protects Mice From Helicobacter-induced Formation of Gastric Lymphoid Tissue. |
Volume: |
159 |
Issue: |
1 |
Pages: |
169-182.e8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bauer S |
Year: |
2023 |
Journal: |
iScience |
Title: |
NLRC5 affects diet-induced adiposity in female mice and co-regulates peroxisome proliferator-activated receptor PPARγ target genes. |
Volume: |
26 |
Issue: |
4 |
Pages: |
106313 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yao Y |
Year: |
2012 |
Journal: |
Cell Res |
Title: |
NLRC5 regulates MHC class I antigen presentation in host defense against intracellular pathogens. |
Volume: |
22 |
Issue: |
5 |
Pages: |
836-47 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tong Y |
Year: |
2012 |
Journal: |
Cell Res |
Title: |
Enhanced TLR-induced NF-κB signaling and type I interferon responses in NLRC5 deficient mice. |
Volume: |
22 |
Issue: |
5 |
Pages: |
822-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun C |
Year: |
2023 |
Journal: |
Int J Mol Sci |
Title: |
NLRC5 Deficiency Reduces LPS-Induced Microglial Activation via Inhibition of NF-κB Signaling and Ameliorates Mice's Depressive-like Behavior. |
Volume: |
24 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Meissner TB |
Year: |
2010 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
NLR family member NLRC5 is a transcriptional regulator of MHC class I genes. |
Volume: |
107 |
Issue: |
31 |
Pages: |
13794-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li P |
Year: |
2020 |
Journal: |
J Neurochem |
Title: |
Neuronal NLRC5 regulates MHC class I expression in Neuro-2a cells and also during hippocampal development. |
Volume: |
152 |
Issue: |
2 |
Pages: |
182-194 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quenum AJI |
Year: |
2021 |
Journal: |
Front Immunol |
Title: |
NLRC5 Deficiency Deregulates Hepatic Inflammatory Response but Does Not Aggravate Carbon Tetrachloride-Induced Liver Fibrosis. |
Volume: |
12 |
|
Pages: |
749646 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang M |
Year: |
2019 |
Journal: |
J Cell Physiol |
Title: |
NLRC5 negatively regulates LTA-induced inflammation via TLR2/NF-κB and participates in TLR2-mediated allergic airway inflammation. |
Volume: |
234 |
Issue: |
11 |
Pages: |
19990-20001 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chen Z |
Year: |
2017 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Dexmedetomidine (DEX) protects against hepatic ischemia/reperfusion (I/R) injury by suppressing inflammation and oxidative stress in NLRC5 deficient mice. |
Volume: |
493 |
Issue: |
2 |
Pages: |
1143-1150 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lupfer CR |
Year: |
2017 |
Journal: |
J Virol |
Title: |
Deficiency of the NOD-Like Receptor NLRC5 Results in Decreased CD8+ T Cell Function and Impaired Viral Clearance. |
Volume: |
91 |
Issue: |
17 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sun T |
Year: |
2019 |
Journal: |
Immunol Cell Biol |
Title: |
NLRC5 deficiency has a moderate impact on immunodominant CD8(+) T-cell responses during rotavirus infection of adult mice. |
Volume: |
97 |
Issue: |
6 |
Pages: |
552-562 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ludigs K |
Year: |
2015 |
Journal: |
PLoS Genet |
Title: |
NLRC5 exclusively transactivates MHC class I and related genes through a distinctive SXY module. |
Volume: |
11 |
Issue: |
3 |
Pages: |
e1005088 |
|
•
•
•
•
•
|
Publication |
First Author: |
Staehli F |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
NLRC5 deficiency selectively impairs MHC class I- dependent lymphocyte killing by cytotoxic T cells. |
Volume: |
188 |
Issue: |
8 |
Pages: |
3820-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Q |
Year: |
2018 |
Journal: |
Kidney Int |
Title: |
NLRC5 deficiency protects against acute kidney injury in mice by mediating carcinoembryonic antigen-related cell adhesion molecule 1 signaling. |
Volume: |
94 |
Issue: |
3 |
Pages: |
551-566 |
|
•
•
•
•
•
|
Publication |
First Author: |
Zebertavage LK |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
Transcriptional Upregulation of NLRC5 by Radiation Drives STING- and Interferon-Independent MHC-I Expression on Cancer Cells and T Cell Cytotoxicity. |
Volume: |
10 |
Issue: |
1 |
Pages: |
7376 |
|
•
•
•
•
•
|
Publication |
First Author: |
Biswas A |
Year: |
2012 |
Journal: |
J Immunol |
Title: |
Cutting edge: impaired MHC class I expression in mice deficient for Nlrc5/class I transactivator. |
Volume: |
189 |
Issue: |
2 |
Pages: |
516-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Robbins GR |
Year: |
2012 |
Journal: |
J Biol Chem |
Title: |
Regulation of class I major histocompatibility complex (MHC) by nucleotide-binding domain, leucine-rich repeat-containing (NLR) proteins. |
Volume: |
287 |
Issue: |
29 |
Pages: |
24294-303 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6382938 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6383060 |
Age: |
postnatal week 1 |
Image: |
5 |
|
Specimen Label: |
1w Control |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6382938 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6383060 |
Age: |
postnatal week 1 |
Image: |
5 |
|
Specimen Label: |
1w Cnot3LKO |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6382938 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6383060 |
Age: |
postnatal week 4 |
Image: |
5 |
|
Specimen Label: |
4w Control |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6382938 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-01-02 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6383060 |
Age: |
postnatal week 4 |
Image: |
5 |
|
Specimen Label: |
4w Cnot3LKO |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bagri P |
Year: |
2017 |
Journal: |
J Virol |
Title: |
Novel Role for Interleukin-17 in Enhancing Type 1 Helper T Cell Immunity in the Female Genital Tract following Mucosal Herpes Simplex Virus 2 Vaccination. |
Volume: |
91 |
Issue: |
23 |
|
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
1 |
Description: |
Protein NLRC5 |
Type: |
chain |
End: |
1915 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mathé J |
Year: |
2022 |
Journal: |
J Immunol |
Title: |
Regulation of MHC Class I Expression in Lung Epithelial Cells during Inflammation. |
Volume: |
208 |
Issue: |
5 |
Pages: |
1021-1033 |
|
•
•
•
•
•
|
Publication |
First Author: |
Benhammadi M |
Year: |
2020 |
Journal: |
J Immunol |
Title: |
IFN-λ Enhances Constitutive Expression of MHC Class I Molecules on Thymic Epithelial Cells. |
Volume: |
205 |
Issue: |
5 |
Pages: |
1268-1280 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aachoui Y |
Year: |
2015 |
Journal: |
Cell Host Microbe |
Title: |
Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium. |
Volume: |
18 |
Issue: |
3 |
Pages: |
320-32 |
|
•
•
•
•
•
|
Publication |
First Author: |
Han JH |
Year: |
2024 |
Journal: |
Nat Commun |
Title: |
NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and heat stress. |
Volume: |
15 |
Issue: |
1 |
Pages: |
1739 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sabrautzki S |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced by the Munich ENU mutagenesis project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Suzuki T |
Year: |
2019 |
Journal: |
Development |
Title: |
Postnatal liver functional maturation requires Cnot complex-mediated decay of mRNAs encoding cell cycle and immature liver genes. |
Volume: |
146 |
Issue: |
4 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Archambaud C |
Year: |
2012 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Impact of lactobacilli on orally acquired listeriosis. |
Volume: |
109 |
Issue: |
41 |
Pages: |
16684-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
Data Curation Using Mouse Genome Assembly |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lennon G |
Year: |
1999 |
Journal: |
Database Download |
Title: |
WashU-HHMI Mouse EST Project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Mouse Radiation Hybrid Database |
Year: |
2004 |
Journal: |
Database Release |
Title: |
Mouse T31 Radiation Hybrid Data Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1393
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1915
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
1392
 |
Fragment?: |
false |
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