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Search results 1 to 100 out of 146 for Nlrp12

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0.056s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Vladimer GI
Year: 2012
Journal: Immunity
Title: The NLRP12 inflammasome recognizes Yersinia pestis.
Volume: 37
Issue: 1
Pages: 96-107
Publication
First Author: Zaki MH
Year: 2011
Journal: Cancer Cell
Title: The NOD-like receptor NLRP12 attenuates colon inflammation and tumorigenesis.
Volume: 20
Issue: 5
Pages: 649-60
Publication  
First Author: Lin Q
Year: 2020
Journal: JCI Insight
Title: Persistent DNA damage-induced NLRP12 improves hematopoietic stem cell function.
Volume: 5
Issue: 10
Publication
First Author: Hornick EE
Year: 2018
Journal: J Immunol
Title: Nlrp12 Mediates Adverse Neutrophil Recruitment during Influenza Virus Infection.
Volume: 200
Issue: 3
Pages: 1188-1197
Publication
First Author: Chen ST
Year: 2019
Journal: Cell Host Microbe
Title: NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25.
Volume: 25
Issue: 4
Pages: 602-616.e7
Publication  
First Author: Ulland TK
Year: 2016
Journal: Nat Commun
Title: Nlrp12 mutation causes C57BL/6J strain-specific defect in neutrophil recruitment.
Volume: 7
Pages: 13180
Publication
First Author: Lee EJ
Year: 2022
Journal: J Neuroinflammation
Title: The innate immune receptor Nlrp12 suppresses autoimmunity to the retina.
Volume: 19
Issue: 1
Pages: 69
Publication
First Author: Krauss JL
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: NLRP12 provides a critical checkpoint for osteoclast differentiation.
Volume: 112
Issue: 33
Pages: 10455-60
Publication
First Author: Allen IC
Year: 2012
Journal: PLoS One
Title: Characterization of NLRP12 during the development of allergic airway disease in mice.
Volume: 7
Issue: 1
Pages: e30612
Publication
First Author: Linz BM
Year: 2017
Journal: J Immunol
Title: Innate Immune Cell Recovery Is Positively Regulated by NLRP12 during Emergency Hematopoiesis.
Volume: 198
Issue: 6
Pages: 2426-2433
Publication
First Author: Chen L
Year: 2017
Journal: Nat Immunol
Title: NLRP12 attenuates colon inflammation by maintaining colonic microbial diversity and promoting protective commensal bacterial growth.
Volume: 18
Issue: 5
Pages: 541-551
Publication
First Author: Truax AD
Year: 2018
Journal: Cell Host Microbe
Title: The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis.
Volume: 24
Issue: 3
Pages: 364-378.e6
Publication
First Author: Prado DS
Year: 2020
Journal: FASEB J
Title: NLRP12 controls arthritis severity by acting as a checkpoint inhibitor of Th17 cell differentiation.
Volume: 34
Issue: 8
Pages: 10907-10919
Publication
First Author: Allen IC
Year: 2013
Journal: PLoS One
Title: Characterization of NLRP12 during the in vivo host immune response to Klebsiella pneumoniae and Mycobacterium tuberculosis.
Volume: 8
Issue: 4
Pages: e60842
Publication  
First Author: Khan S
Year: 2023
Journal: J Clin Invest
Title: NLRP12 downregulates the Wnt/β-catenin pathway via interaction with STK38 to suppress colorectal cancer.
Volume: 133
Issue: 19
Publication
First Author: Arthur JC
Year: 2010
Journal: J Immunol
Title: Cutting edge: NLRP12 controls dendritic and myeloid cell migration to affect contact hypersensitivity.
Volume: 185
Issue: 8
Pages: 4515-9
Publication    
First Author: Udden SN
Year: 2019
Journal: Elife
Title: NLRP12 suppresses hepatocellular carcinoma via downregulation of cJun N-terminal kinase activation in the hepatocyte.
Volume: 8
Publication
First Author: Normand S
Year: 2018
Journal: Nat Commun
Title: Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Volume: 9
Issue: 1
Pages: 5338
Publication
First Author: Allen IC
Year: 2012
Journal: Immunity
Title: NLRP12 suppresses colon inflammation and tumorigenesis through the negative regulation of noncanonical NF-κB signaling.
Volume: 36
Issue: 5
Pages: 742-54
Publication
First Author: Lukens JR
Year: 2015
Journal: Immunity
Title: The NLRP12 Sensor Negatively Regulates Autoinflammatory Disease by Modulating Interleukin-4 Production in T Cells.
Volume: 42
Issue: 4
Pages: 654-64
Publication  
First Author: Abdelhamid L
Year: 2023
Journal: Front Immunol
Title: Nlrp12 deficiency alters gut microbiota and ameliorates Fas(lpr) -mediated systemic autoimmunity in male mice.
Volume: 14
Pages: 1120958
Publication
First Author: Silveira TN
Year: 2017
Journal: Eur J Immunol
Title: NLRP12 negatively regulates proinflammatory cytokine production and host defense against Brucella abortus.
Volume: 47
Issue: 1
Pages: 51-59
Publication
First Author: Zaki MH
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Salmonella exploits NLRP12-dependent innate immune signaling to suppress host defenses during infection.
Volume: 111
Issue: 1
Pages: 385-90
Publication
First Author: Moustaqil M
Year: 2021
Journal: Emerg Microbes Infect
Title: SARS-CoV-2 proteases PLpro and 3CLpro cleave IRF3 and critical modulators of inflammatory pathways (NLRP12 and TAB1): implications for disease presentation across species.
Volume: 10
Issue: 1
Pages: 178-195
Publication
First Author: Ataide MA
Year: 2014
Journal: PLoS Pathog
Title: Malaria-induced NLRP12/NLRP3-dependent caspase-1 activation mediates inflammation and hypersensitivity to bacterial superinfection.
Volume: 10
Issue: 1
Pages: e1003885
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Simon MM
Year: 2013
Journal: Genome Biol
Title: A comparative phenotypic and genomic analysis of C57BL/6J and C57BL/6N mouse strains.
Volume: 14
Issue: 7
Pages: R82
Publication
First Author: Joly S
Year: 2012
Journal: J Immunol
Title: Cutting edge: Nlrp10 is essential for protective antifungal adaptive immunity against Candida albicans.
Volume: 189
Issue: 10
Pages: 4713-7
Publication
First Author: Clay GM
Year: 2017
Journal: J Immunol
Title: An Anti-Inflammatory Role for NLRP10 in Murine Cutaneous Leishmaniasis.
Volume: 199
Issue: 8
Pages: 2823-2833
Publication
First Author: Hornung V
Year: 2009
Journal: Nature
Title: AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC.
Volume: 458
Issue: 7237
Pages: 514-8
Publication
First Author: Janowski AM
Year: 2016
Journal: J Clin Invest
Title: NLRC4 suppresses melanoma tumor progression independently of inflammasome activation.
Volume: 126
Issue: 10
Pages: 3917-3928
Publication
First Author: Yang D
Year: 2015
Journal: Immunity
Title: Caspase-11 Requires the Pannexin-1 Channel and the Purinergic P2X7 Pore to Mediate Pyroptosis and Endotoxic Shock.
Volume: 43
Issue: 5
Pages: 923-32
Publication
First Author: Weng D
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 and RIP kinases regulate bacteria-induced innate immune responses and cell death.
Volume: 111
Issue: 20
Pages: 7391-6
Publication
First Author: Madissoon E
Year: 2014
Journal: PLoS One
Title: Differences in gene expression between mouse and human for dynamically regulated genes in early embryo.
Volume: 9
Issue: 8
Pages: e102949
Publication
First Author: Elinav E
Year: 2011
Journal: Cell
Title: NLRP6 inflammasome regulates colonic microbial ecology and risk for colitis.
Volume: 145
Issue: 5
Pages: 745-57
Publication
First Author: Henao-Mejia J
Year: 2012
Journal: Nature
Title: Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity.
Volume: 482
Issue: 7384
Pages: 179-85
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication        
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
Publication
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication      
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Protein
Organism: Mus musculus/domesticus
Length: 706  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 741  
Fragment?: false
Publication
First Author: Pinheiro AS
Year: 2011
Journal: J Mol Biol
Title: The NLRP12 pyrin domain: structure, dynamics, and functional insights.
Volume: 413
Issue: 4
Pages: 790-803
Interaction Experiment
Description: NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25.
DO Term
Allele
Name: NLR family, pyrin domain containing 12; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Stein C
Year: 2007
Journal: Genome Biol
Title: Conservation and divergence of gene families encoding components of innate immune response systems in zebrafish.
Volume: 8
Issue: 11
Pages: R251
Publication
First Author: Manji GA
Year: 2002
Journal: J Biol Chem
Title: PYPAF1, a PYRIN-containing Apaf1-like protein that assembles with ASC and regulates activation of NF-kappa B.
Volume: 277
Issue: 13
Pages: 11570-5
Protein Domain
Type: Domain
Description: This domain is frequently found associated with the NACHT domain () in fish and other vertebrates []. Proteins containing this domain include NACHT, LRR and PYD domains-containing protein 3/12 (NLRP3/12). In humans, NLRP3 (also known as PYPAF1) may function as an inducer of apoptosis []. NLRP12 is a non-inflammasome NLR (nucleotide-binding domain and leucine-rich repeat-containing receptors) that has been implicated in the regulation of Toll-like receptor-dependent nuclear factor-kappaB activation [].
Allele
Name: transgene insertion 1, Lionel Larue
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Strain
Attribute String: transgenic, mutant strain, congenic
Publication  
First Author: Bernardazzi C
Year: 2022
Journal: Int J Mol Sci
Title: The P2X7 Receptor Promotes Colorectal Inflammation and Tumorigenesis by Modulating Gut Microbiota and the Inflammasome.
Volume: 23
Issue: 9
Publication
First Author: Lord CA
Year: 2009
Journal: J Immunol
Title: Blimp-1/PRDM1 mediates transcriptional suppression of the NLR gene NLRP12/Monarch-1.
Volume: 182
Issue: 5
Pages: 2948-58
Publication
First Author: Pedersen M
Year: 2013
Journal: Cancer Discov
Title: Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Volume: 3
Issue: 4
Pages: 458-469