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Search results 1 to 100 out of 102 for Nlrp1a

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Hits by Strain

Type Details Score
Gene
360557 | Nlrp1a
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2684861 | Nlrp1a
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24606891 | J:210638
First Author: Gerlic M
Year: 2014
Journal: Cell Metab
Title: NLRP1a expression in Srebp-1a-deficient mice.
Volume: 19
Issue: 3
Pages: 345-6
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Publication
23506131 | J:194517
 
First Author: Sastalla I
Year: 2013
Journal: BMC Genomics
Title: Transcriptional analysis of the three Nlrp1 paralogs in mice.
Volume: 14
Pages: 188
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Publication
30214011 | J:267658
First Author: Tye H
Year: 2018
Journal: Nat Commun
Title: NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.
Volume: 9
Issue: 1
Pages: 3728
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Publication
23219391 | J:191055
First Author: Masters SL
Year: 2012
Journal: Immunity
Title: NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.
Volume: 37
Issue: 6
Pages: 1009-23
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Publication
- | J:265173
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for watermelon.
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Publication
26603191 | J:232742
First Author: Murphy AJ
Year: 2016
Journal: Cell Metab
Title: IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Volume: 23
Issue: 1
Pages: 155-64
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Publication
36112693 | J:336811
First Author: Harapas CR
Year: 2022
Journal: Sci Immunol
Title: DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Volume: 7
Issue: 75
Pages: eabi4611
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Publication
32421904 | J:304482
First Author: Greaney AJ
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1? release is a neutrophil and PAD4-dependent event.
Volume: 108
Issue: 3
Pages: 773-786
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
ENSMUSG00200048824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00195051866 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220054039 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180053319 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175041191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2684861 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215049066 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005048131 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210050823 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185054630 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205050901 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230052701 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000056945 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190034932 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225039022 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010053371 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOG00005041052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017791 | -
Type: protein_coding_gene
Organism: Mus pahari
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
16429160 | J:99748
First Author: Boyden ED
Year: 2006
Journal: Nat Genet
Title: Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin.
Volume: 38
Issue: 2
Pages: 240-4
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Publication
18511561 | J:169881
First Author: Hsu LC
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: A NOD2-NALP1 complex mediates caspase-1-dependent IL-1beta secretion in response to Bacillus anthracis infection and muramyl dipeptide.
Volume: 105
Issue: 22
Pages: 7803-8
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Publication
24218483 | J:206165
First Author: Ewald SE
Year: 2014
Journal: Infect Immun
Title: NLRP1 is an inflammasome sensor for Toxoplasma gondii.
Volume: 82
Issue: 1
Pages: 460-8
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Publication
19494813 | J:150357
First Author: Guarda G
Year: 2009
Journal: Nature
Title: T cells dampen innate immune responses through inhibition of NLRP1 and NLRP3 inflammasomes.
Volume: 460
Issue: 7252
Pages: 269-73
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Publication
22753929 | J:189777
First Author: Kovarova M
Year: 2012
Journal: J Immunol
Title: NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice.
Volume: 189
Issue: 4
Pages: 2006-16
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Publication
21531336 | J:175815
First Author: Im SS
Year: 2011
Journal: Cell Metab
Title: Linking lipid metabolism to the innate immune response in macrophages through sterol regulatory element binding protein-1a.
Volume: 13
Issue: 5
Pages: 540-9
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Publication
32839316 | J:296026
First Author: Yin Y
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: A noncanonical role of NOD-like receptor NLRP14 in PGCLC differentiation and spermatogenesis.
Volume: 117
Issue: 36
Pages: 22237-22248
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
18495787 | J:138433
First Author: Rosenzweig HL
Year: 2008
Journal: J Leukoc Biol
Title: Activation of NOD2 in vivo induces IL-1beta production in the eye via caspase-1 but results in ocular inflammation independently of IL-1 signaling.
Volume: 84
Issue: 2
Pages: 529-36
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Publication
22444631 | J:187333
First Author: Gross O
Year: 2012
Journal: Immunity
Title: Inflammasome activators induce interleukin-1? secretion via distinct pathways with differential requirement for the protease function of caspase-1.
Volume: 36
Issue: 3
Pages: 388-400
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Publication
19940192 | J:393464
First Author: Soulika AM
Year: 2009
Journal: J Neurosci
Title: Initiation and progression of axonopathy in experimental autoimmune encephalomyelitis.
Volume: 29
Issue: 47
Pages: 14965-79
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
39289506 | J:356843
First Author: Weiss FD
Year: 2024
Journal: Cell Death Differ
Title: Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3(tm1Flv) mice.
Volume: 31
Issue: 12
Pages: 1717-1729
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:384794
     
First Author: MGI and IMPC
Year: 2026
Journal: Database Release
Title: MGI Load of Molecular Notes for Endonuclease-Mediated (CRISPR) Alleles from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34106880 | J:368890
First Author: Chiu YJ
Year: 2021
Journal: Aging (Albany NY)
Title: Formulated Chinese medicine Shaoyao Gancao Tang reduces NLRP1 and NLRP3 in Alzheimer's disease cell and mouse models for neuroprotection and cognitive improvement.
Volume: 13
Issue: 11
Pages: 15620-15637
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
21683629 | J:174307
First Author: Ali SR
Year: 2011
Journal: Immunity
Title: Anthrax toxin induces macrophage death by p38 MAPK inhibition but leads to inflammasome activation via ATP leakage.
Volume: 35
Issue: 1
Pages: 34-44
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Publication
39587068 | J:358940
First Author: Titiz M
Year: 2024
Journal: Nat Commun
Title: Schwann cell C5aR1 co-opts inflammasome NLRP1 to sustain pain in a mouse model of endometriosis.
Volume: 15
Issue: 1
Pages: 10142
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Publication
25144717 | J:351732
First Author: Tan MS
Year: 2014
Journal: Cell Death Dis
Title: Amyloid-? induces NLRP1-dependent neuronal pyroptosis in models of Alzheimer's disease.
Volume: 5
Issue: 8
Pages: e1382
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
19924255 | J:155416
First Author: Averette KM
Year: 2009
Journal: PLoS One
Title: Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent.
Volume: 4
Issue: 11
Pages: e7913
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
24337744 | J:207325
First Author: Maier NK
Year: 2014
Journal: J Immunol
Title: Arsenic trioxide and other arsenical compounds inhibit the NLRP1, NLRP3, and NAIP5/NLRC4 inflammasomes.
Volume: 192
Issue: 2
Pages: 763-70
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Publication
29571734 | J:271229
First Author: Li Y
Year: 2018
Journal: Biochem Biophys Res Commun
Title: NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response.
Volume: 501
Issue: 2
Pages: 351-357
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Publication
30001530 | J:319303
First Author: Zong J
Year: 2018
Journal: Cell Physiol Biochem
Title: Nuclear Localization Leucine-Rich-Repeat Protein 1 Deficiency Protects Against Cardiac Hypertrophy by Pressure Overload.
Volume: 48
Issue: 1
Pages: 75-86
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Publication
31170267 | J:288316
First Author: Lin L
Year: 2019
Journal: PLoS Pathog
Title: An NLRP3 inflammasome-triggered cytokine storm contributes to Streptococcal toxic shock-like syndrome (STSLS).
Volume: 15
Issue: 6
Pages: e1007795
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Publication
- | J:265174
     
First Author: Choi JH
Year: 2018
Journal: MGI Direct Data Submission
Title: Mutagenetix entry for dreary.
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
27993998 | J:354173
First Author: Liu L
Year: 2017
Journal: J Crohns Colitis
Title: The Pathogenic Role of NLRP3 Inflammasome Activation in Inflammatory Bowel Diseases of Both Mice and Humans.
Volume: 11
Issue: 6
Pages: 737-750
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Publication
15967716 | J:114723
First Author: Martinon F
Year: 2005
Journal: Trends Immunol
Title: NLRs join TLRs as innate sensors of pathogens.
Volume: 26
Issue: 8
Pages: 447-54
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Publication
25879281 | J:320796
First Author: Chavarr?a-Smith J
Year: 2015
Journal: Immunol Rev
Title: The NLRP1 inflammasomes.
Volume: 265
Issue: 1
Pages: 22-34
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Publication
12775719 | J:85109
First Author: Stehlik C
Year: 2003
Journal: J Biol Chem
Title: CARD6 is a modulator of NF-kappa B activation by Nod1- and Cardiak-mediated pathways.
Volume: 278
Issue: 34
Pages: 31941-9
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
24606892 | J:210637
First Author: Im SS
Year: 2014
Journal: Cell Metab
Title: Response to Gerlic et al.
Volume: 19
Issue: 3
Pages: 346-7
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Publication
25024200 | J:212247
First Author: Chi W
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-8 promotes NLRP1/NLRP3 inflammasome activation and IL-1? production in acute glaucoma.
Volume: 111
Issue: 30
Pages: 11181-6
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Publication
27926929 | J:245770
First Author: Chavarr?a-Smith J
Year: 2016
Journal: PLoS Pathog
Title: Functional and Evolutionary Analyses Identify Proteolysis as a General Mechanism for NLRP1 Inflammasome Activation.
Volume: 12
Issue: 12
Pages: e1006052
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Publication
24699513 | J:246915
First Author: Cavailles P
Year: 2014
Journal: PLoS Pathog
Title: A highly conserved Toxo1 haplotype directs resistance to toxoplasmosis and its associated caspase-1 dependent killing of parasite and host macrophage.
Volume: 10
Issue: 4
Pages: e1004005
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Allele
Nlrp1a<em1Smoc> | MGI:7291326
Name: NLR family, pyrin domain containing 1A; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Strain
MGI:6355058 | C57BL/6JSmoc-Nlrp1a<em1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, endonuclease-mediated mutation
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Allele
Del(11Nlrp1a-Nlrp1c-ps)1Smas | MGI:5472123
Name: deletion, Chr 11, Seth Masters
Allele Type: Targeted
Attribute String: Null/knockout
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Allele
Nlrp1a<m1Btlr> | MGI:6200049
Name: NLR family, pyrin domain containing 1A; mutation 1, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Strain
MGI:6200050 | C57BL/6J-Nlrp1a<m1Btlr>
Attribute String: chemically induced mutation, coisogenic, mutant strain
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Genotype
Genotype
Symbol: Nlrp1a/Nlrp1a
Background: C57BL/6J-Nlrp1a
Zygosity: hm
Has Mutant Allele: true
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Strain
MGI:6696420 | B6.129P2-Del(11Nlrp1a-Nlrp1c-ps)1Smas/Mmjax
Attribute String: congenic, deletion, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Del(11Nlrp1a-Nlrp1c-ps)1Smas/Del(11Nlrp1a-Nlrp1c-ps)1Smas
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Publication
36155655 | J:336980
   
First Author: Cohen H
Year: 2022
Journal: Elife
Title: Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.
Volume: 11
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Publication
28604600 | J:344759
 
First Author: Znalesniak EB
Year: 2017
Journal: Int J Mol Sci
Title: Transcriptional Responses in the Murine Spleen after Toxoplasma gondii Infection: Inflammasome and Mucus-Associated Genes.
Volume: 18
Issue: 6
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Publication
39047896 | J:387239
First Author: Mazzone RJ
Year: 2024
Journal: Microbes Infect
Title: NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in intestinal epithelial cells.
Volume: 26
Issue: 8
Pages: 105398
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Publication
29551594 | J:260703
First Author: Nakamura K
Year: 2018
Journal: Cancer Cell
Title: Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.
Volume: 33
Issue: 4
Pages: 634-648.e5
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Publication
39250503 | J:375564
First Author: Goris M
Year: 2024
Journal: PLoS Pathog
Title: NLRP1-dependent activation of Gasdermin D in neutrophils controls cutaneous leishmaniasis.
Volume: 20
Issue: 9
Pages: e1012527
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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