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Search results 1 to 100 out of 102 for Nlrp1b

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Type Details Score
Gene
691998 | Nlrp1b
Type: gene
Organism: rat
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Protein Coding Gene
MGI:3582959 | Nlrp1b
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
24492532 | J:244194
 
First Author: Van Opdenbosch N
Year: 2014
Journal: Nat Commun
Title: Activation of the NLRP1b inflammasome independently of ASC-mediated caspase-1 autoproteolysis and speck formation.
Volume: 5
Pages: 3209
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Publication
29396289 | J:273615
First Author: Okondo MC
Year: 2018
Journal: Cell Chem Biol
Title: Inhibition of Dpp8/9 Activates the Nlrp1b Inflammasome.
Volume: 25
Issue: 3
Pages: 262-267.e5
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Publication
29262324 | J:254284
First Author: Van Opdenbosch N
Year: 2017
Journal: Cell Rep
Title: Caspase-1 Engagement and TLR-Induced c-FLIP Expression Suppress ASC/Caspase-8-Dependent Apoptosis by Inflammasome Sensors NLRP1b and NLRC4.
Volume: 21
Issue: 12
Pages: 3427-3444
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Publication
30718379 | J:285504
 
First Author: de Vasconcelos NM
Year: 2019
Journal: Life Sci Alliance
Title: DPP8/DPP9 inhibition elicits canonical Nlrp1b inflammasome hallmarks in murine macrophages.
Volume: 2
Issue: 1
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Publication
23230290 | J:192547
First Author: Liao KC
Year: 2013
Journal: Infect Immun
Title: Activation of the Nlrp1b inflammasome by reduction of cytosolic ATP.
Volume: 81
Issue: 2
Pages: 570-9
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Publication
23152930 | J:195467
First Author: Hellmich KA
Year: 2012
Journal: PLoS One
Title: Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages.
Volume: 7
Issue: 11
Pages: e49741
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Publication
35256512 | J:325672
First Author: Chiaranunt P
Year: 2022
Journal: J Immunol
Title: NLRP1B and NLRP3 Control the Host Response following Colonization with the Commensal Protist Tritrichomonas musculis.
Volume: 208
Issue: 7
Pages: 1782-1789
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Publication
35784371 | J:364639
 
First Author: Murase Y
Year: 2022
Journal: Front Immunol
Title: UVB-Induced Skin Autoinflammation Due to Nlrp1b Mutation and Its Inhibition by Anti-IL-1? Antibody.
Volume: 13
Pages: 876390
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Publication
25404286 | J:216652
First Author: Guey B
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Caspase-1 autoproteolysis is differentially required for NLRP1b and NLRP3 inflammasome function.
Volume: 111
Issue: 48
Pages: 17254-9
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Publication
39047896 | J:387239
First Author: Mazzone RJ
Year: 2024
Journal: Microbes Infect
Title: NLRP1B allele 2 does not respond to Val-boro-Pro (VbP) in intestinal epithelial cells.
Volume: 26
Issue: 8
Pages: 105398
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Publication
31554824 | J:284667
First Author: Salazar-Le?n J
Year: 2019
Journal: Sci Rep
Title: Nlrp1b1 negatively modulates obesity-induced inflammation by promoting IL-18 production.
Volume: 9
Issue: 1
Pages: 13815
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Publication
19949100 | J:159005
First Author: Terra JK
Year: 2010
Journal: J Immunol
Title: Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.
Volume: 184
Issue: 1
Pages: 17-20
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Publication
21170303 | J:168096
First Author: Moayeri M
Year: 2010
Journal: PLoS Pathog
Title: Inflammasome sensor Nlrp1b-dependent resistance to anthrax is mediated by caspase-1, IL-1 signaling and neutrophil recruitment.
Volume: 6
Issue: 12
Pages: e1001222
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Publication
32421904 | J:304482
First Author: Greaney AJ
Year: 2020
Journal: J Leukoc Biol
Title: Frontline Science: Anthrax lethal toxin-induced, NLRP1-mediated IL-1? release is a neutrophil and PAD4-dependent event.
Volume: 108
Issue: 3
Pages: 773-786
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Publication
16429160 | J:99748
First Author: Boyden ED
Year: 2006
Journal: Nat Genet
Title: Nalp1b controls mouse macrophage susceptibility to anthrax lethal toxin.
Volume: 38
Issue: 2
Pages: 240-4
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Publication
23506131 | J:194517
 
First Author: Sastalla I
Year: 2013
Journal: BMC Genomics
Title: Transcriptional analysis of the three Nlrp1 paralogs in mice.
Volume: 14
Pages: 188
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Protein Coding Gene
ENSMUSG00195051920 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00220054059 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00180051990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00175041842 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3582959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00215049609 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSTCUG00005053577 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00210051037 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00185054666 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00205052167 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00230052819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSUMUG00000056951 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00190035081 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSMUSG00225039119 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSLUMG00010053375 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
ENSIUOGG00005054459 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0017792 | -
Type: protein_coding_gene
Organism: Mus pahari
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Publication
38409108 | J:361094
First Author: Han JH
Year: 2024
Journal: Nat Commun
Title: NINJ1 mediates inflammatory cell death, PANoptosis, and lethality during infection conditions and?heat stress.
Volume: 15
Issue: 1
Pages: 1739
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Publication
22753929 | J:189777
First Author: Kovarova M
Year: 2012
Journal: J Immunol
Title: NLRP1-dependent pyroptosis leads to acute lung injury and morbidity in mice.
Volume: 189
Issue: 4
Pages: 2006-16
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Publication
23226472 | J:192443
First Author: Hesker PR
Year: 2012
Journal: PLoS One
Title: Genetic loss of murine pyrin, the Familial Mediterranean Fever protein, increases interleukin-1? levels.
Volume: 7
Issue: 11
Pages: e51105
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Publication
38053332 | J:348863
First Author: Kumar SRP
Year: 2024
Journal: Mol Ther
Title: TLR9-independent CD8(+) T?cell responses in hepatic AAV gene transfer through IL-1R1-MyD88 signaling.
Volume: 32
Issue: 2
Pages: 325-339
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Publication
21349431 | J:168972
First Author: Guarda G
Year: 2011
Journal: Immunity
Title: Type I interferon inhibits interleukin-1 production and inflammasome activation.
Volume: 34
Issue: 2
Pages: 213-23
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Publication
32853276 | J:329681
First Author: Kongsomboonvech AK
Year: 2020
Journal: PLoS Pathog
Title: Na?ve CD8 T cell IFN? responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5.
Volume: 16
Issue: 8
Pages: e1008327
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Publication
34038731 | J:324648
First Author: Costa FRC
Year: 2021
Journal: Cell Rep
Title: NLRP1 acts as a negative regulator of Th17 cell programming in mice and humans with autoimmune diabetes.
Volume: 35
Issue: 8
Pages: 109176
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Publication
37855658 | J:361155
First Author: Gao X
Year: 2024
Journal: Protein Cell
Title: Anthrax lethal toxin and tumor necrosis factor-? synergize on intestinal epithelia to induce mouse death.
Volume: 15
Issue: 2
Pages: 135-148
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Publication
31558613 | J:392555
First Author: Deng M
Year: 2019
Journal: J Exp Med
Title: Platelet-activating factor (PAF) mediates NLRP3-NEK7 inflammasome induction independently of PAFR.
Volume: 216
Issue: 12
Pages: 2838-2853
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
20188815 | J:159207
First Author: Nakajima K
Year: 2010
Journal: Microb Pathog
Title: Exclusion of Kif1c as a candidate gene for anthrax toxin susceptibility.
Volume: 48
Issue: 5
Pages: 188-90
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Publication
25744023 | J:258544
First Author: Kaushal V
Year: 2015
Journal: Cell Death Differ
Title: Neuronal NLRP1 inflammasome activation of Caspase-1 coordinately regulates inflammatory interleukin-1-beta production and axonal degeneration-associated Caspase-6 activation.
Volume: 22
Issue: 10
Pages: 1676-86
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Publication
37998361 | J:342947
 
First Author: Spurlock M
Year: 2023
Journal: Cells
Title: The Inflammasome-Dependent Dysfunction and Death of Retinal Ganglion Cells after Repetitive Intraocular Pressure Spikes.
Volume: 12
Issue: 22
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Publication
34986653 | J:362554
First Author: Menendez M
Year: 2022
Journal: Circ Res
Title: IL-1? Impacts Vascular Integrity and Lymphatic Function in the Embryonic Omentum.
Volume: 130
Issue: 3
Pages: 366-383
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
29571734 | J:271229
First Author: Li Y
Year: 2018
Journal: Biochem Biophys Res Commun
Title: NLRP1 deficiency attenuates diabetic retinopathy (DR) in mice through suppressing inflammation response.
Volume: 501
Issue: 2
Pages: 351-357
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Publication
30001530 | J:319303
First Author: Zong J
Year: 2018
Journal: Cell Physiol Biochem
Title: Nuclear Localization Leucine-Rich-Repeat Protein 1 Deficiency Protects Against Cardiac Hypertrophy by Pressure Overload.
Volume: 48
Issue: 1
Pages: 75-86
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
25879281 | J:320796
First Author: Chavarr?a-Smith J
Year: 2015
Journal: Immunol Rev
Title: The NLRP1 inflammasomes.
Volume: 265
Issue: 1
Pages: 22-34
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Publication
17442855 | J:123498
First Author: Lamkanfi M
Year: 2007
Journal: J Leukoc Biol
Title: Caspase-1 inflammasomes in infection and inflammation.
Volume: 82
Issue: 2
Pages: 220-5
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:389486
     
First Author: Mouse Genome Informatics and Ensembl Genome Database Project
Year: 2026
Journal: Database Release
Title: MGI Strain Genome Feature and Gene Model Load from Ensembl.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:109762
     
First Author: Mouse Genome Informatics and VEGA Genome Database Project
Year: 2006
Journal: Database Release
Title: Collaboration to Associate VEGA (Vertebrate Genome Annotation) Mouse Gene Models with MGI Markers
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Publication
31268597 | J:306597
First Author: Xu H
Year: 2019
Journal: EMBO J
Title: The N-end rule ubiquitin ligase UBR2 mediates NLRP1B inflammasome activation by anthrax lethal toxin.
Volume: 38
Issue: 13
Pages: e101996
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Publication
30872531 | -
First Author: Chui AJ
Year: 2019
Journal: Science
Title: N-terminal degradation activates the NLRP1B inflammasome.
Volume: 364
Issue: 6435
Pages: 82-85
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Publication
22241984 | J:183296
First Author: Terra JK
Year: 2011
Journal: PLoS Pathog
Title: Allelic variation on murine chromosome 11 modifies host inflammatory responses and resistance to Bacillus anthracis.
Volume: 7
Issue: 12
Pages: e1002469
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Publication
22536155 | -
First Author: Frew BC
Year: 2012
Journal: PLoS Pathog
Title: Proteolytic processing of Nlrp1b is required for inflammasome activity.
Volume: 8
Issue: 4
Pages: e1002659
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Publication
19924255 | J:155416
First Author: Averette KM
Year: 2009
Journal: PLoS One
Title: Anthrax lethal toxin induced lysosomal membrane permeabilization and cytosolic cathepsin release is Nlrp1b/Nalp1b-dependent.
Volume: 4
Issue: 11
Pages: e7913
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Publication
24935976 | -
First Author: Neiman-Zenevich J
Year: 2014
Journal: Infect Immun
Title: Distinct regions of NLRP1B are required to respond to anthrax lethal toxin and metabolic inhibition.
Volume: 82
Issue: 9
Pages: 3697-703
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Publication
19651869 | -
First Author: Liao KC
Year: 2009
Journal: Infect Immun
Title: Expression of Nlrp1b inflammasome components in human fibroblasts confers susceptibility to anthrax lethal toxin.
Volume: 77
Issue: 10
Pages: 4455-62
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Publication
23818853 | -
First Author: Chavarr?a-Smith J
Year: 2013
Journal: PLoS Pathog
Title: Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor.
Volume: 9
Issue: 6
Pages: e1003452
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Allele
Tg(Nlrp1b)1Die | MGI:3695919
Name: transgene insertion 1, William Dietrich
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Allele
Nlrp1b<tm1Smoc> | MGI:7786913
Name: NLR family, pyrin domain containing 1B; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Conditional ready, No functional change
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HT Experiment
GSE172065 | UVB-induced skin autoinflammation due to NLRP1 mutation and its inhibition by anti-IL-1b antibody
 
Experiment Type: RNA-Seq
Study Type: WT vs. Mutant
Source: GEO
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Strain
MGI:3695900 | B6.Cg-Tg(Nlrp1b)1Die/DieJ
Attribute String: congenic, mutant strain, transgenic
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Genotype
Genotype
Symbol: Tg(Nlrp1b)1Die/?
Background: involves: 129S1/SvImJ * C57BL/6 * SJL
Zygosity: ot
Has Mutant Allele: true
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Publication
32726624 | J:323547
First Author: de Vasconcelos NM
Year: 2020
Journal: Cell Rep
Title: An Apoptotic Caspase Network Safeguards Cell Death Induction in Pyroptotic Macrophages.
Volume: 32
Issue: 4
Pages: 107959
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Strain
MGI:7788754 | C57BL/6JSmoc-Nlrp1b<tm1Smoc>/Smoc
Attribute String: coisogenic, mutant strain, targeted mutation
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Transgene
MGI:3695918 | Tg(Nlrp1b)1Die
Type: transgene
Organism: mouse, laboratory
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Allele
Del(11Nlrp1a-Nlrp1c-ps)1Smas | MGI:5472123
Name: deletion, Chr 11, Seth Masters
Allele Type: Targeted
Attribute String: Null/knockout
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Strain
MGI:6696420 | B6.129P2-Del(11Nlrp1a-Nlrp1c-ps)1Smas/Mmjax
Attribute String: congenic, deletion, mutant strain, targeted mutation
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Genotype
Genotype
Symbol: Del(11Nlrp1a-Nlrp1c-ps)1Smas/Del(11Nlrp1a-Nlrp1c-ps)1Smas
Background: Not Specified
Zygosity: hm
Has Mutant Allele: true
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Publication
30214011 | J:267658
First Author: Tye H
Year: 2018
Journal: Nat Commun
Title: NLRP1 restricts butyrate producing commensals to exacerbate inflammatory bowel disease.
Volume: 9
Issue: 1
Pages: 3728
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Publication
36155655 | J:336980
   
First Author: Cohen H
Year: 2022
Journal: Elife
Title: Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.
Volume: 11
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Publication
24218483 | J:206165
First Author: Ewald SE
Year: 2014
Journal: Infect Immun
Title: NLRP1 is an inflammasome sensor for Toxoplasma gondii.
Volume: 82
Issue: 1
Pages: 460-8
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Publication
39289506 | J:356843
First Author: Weiss FD
Year: 2024
Journal: Cell Death Differ
Title: Retention of ES cell-derived 129S genome drives NLRP1 hypersensitivity and transcriptional deregulation in Nlrp3(tm1Flv) mice.
Volume: 31
Issue: 12
Pages: 1717-1729
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Publication
26603191 | J:232742
First Author: Murphy AJ
Year: 2016
Journal: Cell Metab
Title: IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Volume: 23
Issue: 1
Pages: 155-64
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Publication
29551594 | J:260703
First Author: Nakamura K
Year: 2018
Journal: Cancer Cell
Title: Dysregulated IL-18 Is a Key Driver of Immunosuppression and a Possible Therapeutic Target in the Multiple Myeloma Microenvironment.
Volume: 33
Issue: 4
Pages: 634-648.e5
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Publication
22792226 | J:189511
First Author: Weigel KJ
Year: 2012
Journal: PLoS One
Title: Rapid vascular responses to anthrax lethal toxin in mice containing a segment of chromosome 11 from the CAST/Ei strain on a C57BL/6 genetic background.
Volume: 7
Issue: 7
Pages: e40126
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Publication
36112693 | J:336811
First Author: Harapas CR
Year: 2022
Journal: Sci Immunol
Title: DPP9 deficiency: An inflammasomopathy that can be rescued by lowering NLRP1/IL-1 signaling.
Volume: 7
Issue: 75
Pages: eabi4611
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Publication
39250503 | J:375564
First Author: Goris M
Year: 2024
Journal: PLoS Pathog
Title: NLRP1-dependent activation of Gasdermin D in neutrophils controls cutaneous leishmaniasis.
Volume: 20
Issue: 9
Pages: e1012527
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Publication
23219391 | J:191055
First Author: Masters SL
Year: 2012
Journal: Immunity
Title: NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.
Volume: 37
Issue: 6
Pages: 1009-23
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Publication
39112714 | J:361872
First Author: Cao J
Year: 2024
Journal: Nature
Title: DNA-sensing inflammasomes cause recurrent atherosclerotic stroke.
Volume: 633
Issue: 8029
Pages: 433-441
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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