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Search results 1 to 100 out of 5466 for Nlrp3

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4.697s

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Type Details Score
Gene
114548 | NLRP3
Type: gene
Organism: human
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Gene
538639 | NLRP3
Type: gene
Organism: cattle
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Gene
423021 | NLRP3
Type: gene
Organism: chicken
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Gene
567964 | nlrp3
Type: gene
Organism: zebrafish
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Gene
701278 | NLRP3
Type: gene
Organism: macaque, rhesus
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Gene
100497524 | nlrp3
Type: gene
Organism: frog, western clawed
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Gene
287362 | Nlrp3
Type: gene
Organism: rat
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Gene
490576 | NLRP3
Type: gene
Organism: dog, domestic
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Gene
469743 | NLRP3
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:2653833 | Nlrp3
Type: protein_coding_gene
Organism: mouse, laboratory
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GO Term
GO:0044546 | NLRP3 inflammasome complex assembly
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Publication
30455347 | J:274726
First Author: Billon C
Year: 2019
Journal: J Biol Chem
Title: RORγ regulates the NLRP3 inflammasome.
Volume: 294
Issue: 1
Pages: 10-19
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Publication
24478101 | J:209805
First Author: Mao L
Year: 2014
Journal: Infect Immun
Title: Pathogenic fungus Microsporum canis activates the NLRP3 inflammasome.
Volume: 82
Issue: 2
Pages: 882-92
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Publication
26119741 | J:224854
First Author: Wang H
Year: 2015
Journal: Cell Rep
Title: Reciprocal Regulation between Enterovirus 71 and the NLRP3 Inflammasome.
Volume: 12
Issue: 1
Pages: 42-48
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Publication
31013297 | J:275013
First Author: Ojcius DM
Year: 2019
Journal: PLoS One
Title: Dicer regulates activation of the NLRP3 inflammasome.
Volume: 14
Issue: 4
Pages: e0215689
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Publication
25762200 | J:221886
 
First Author: dos Santos G
Year: 2015
Journal: Nat Commun
Title: Vimentin regulates activation of the NLRP3 inflammasome.
Volume: 6
Pages: 6574
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Publication
31748742 | J:287425
First Author: Ising C
Year: 2019
Journal: Nature
Title: NLRP3 inflammasome activation drives tau pathology.
Volume: 575
Issue: 7784
Pages: 669-673
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Publication
30787184 | J:277205
 
First Author: Ren G
Year: 2019
Journal: EMBO J
Title: ABRO1 promotes NLRP3 inflammasome activation through regulation of NLRP3 deubiquitination.
Volume: 38
Issue: 6
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Publication
30080445 | J:283796
First Author: Wang C
Year: 2019
Journal: FASEB J
Title: NLRP3 deficiency exacerbates enterovirus infection in mice.
Volume: 33
Issue: 1
Pages: 942-952
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Publication
19596994 | J:151582
First Author: Li H
Year: 2009
Journal: J Immunol
Title: Cutting edge: Necrosis activates the NLRP3 inflammasome.
Volume: 183
Issue: 3
Pages: 1528-32
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Publication
27803035 | J:260780
First Author: Bruder-Nascimento T
Year: 2016
Journal: Circulation
Title: NLRP3 Inflammasome Mediates Aldosterone-Induced Vascular Damage.
Volume: 134
Issue: 23
Pages: 1866-1880
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Publication
29358279 | J:258416
First Author: Deigendesch N
Year: 2018
Journal: J Immunol
Title: Copper Regulates the Canonical NLRP3 Inflammasome.
Volume: 200
Issue: 5
Pages: 1607-1617
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Publication
27139490 | J:234785
First Author: Qu Y
Year: 2016
Journal: J Exp Med
Title: NLRP3 recruitment by NLRC4 during Salmonella infection.
Volume: 213
Issue: 6
Pages: 877-85
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Publication
22981536 | J:187661
First Author: Compan V
Year: 2012
Journal: Immunity
Title: Cell volume regulation modulates NLRP3 inflammasome activation.
Volume: 37
Issue: 3
Pages: 487-500
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Publication
24917577 | J:230097
First Author: Henriksbo BD
Year: 2014
Journal: Diabetes
Title: Fluvastatin causes NLRP3 inflammasome-mediated adipose insulin resistance.
Volume: 63
Issue: 11
Pages: 3742-7
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Publication
32929041 | J:303587
First Author: Zhao W
Year: 2020
Journal: J Immunol
Title: AKT Regulates NLRP3 Inflammasome Activation by Phosphorylating NLRP3 Serine 5.
Volume: 205
Issue: 8
Pages: 2255-2264
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Publication
21257968 | J:168987
First Author: Guarda G
Year: 2011
Journal: J Immunol
Title: Differential expression of NLRP3 among hematopoietic cells.
Volume: 186
Issue: 4
Pages: 2529-34
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Publication
35868482 | J:327144
First Author: Zhou T
Year: 2022
Journal: Biochim Biophys Acta Mol Basis Dis
Title: GYY4137 ameliorates sepsis-induced cardiomyopathy via NLRP3 pathway.
Volume: 1868
Issue: 12
Pages: 166497
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Publication
26642356 | J:226677
First Author: Shi H
Year: 2016
Journal: Nat Immunol
Title: NLRP3 activation and mitosis are mutually exclusive events coordinated by NEK7, a new inflammasome component.
Volume: 17
Issue: 3
Pages: 250-8
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Publication
30487600 | J:267662
First Author: Chen J
Year: 2018
Journal: Nature
Title: PtdIns4P on dispersed trans-Golgi network mediates NLRP3 inflammasome activation.
Volume: 564
Issue: 7734
Pages: 71-76
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Publication
23809161 | J:207576
First Author: Muñoz-Planillo R
Year: 2013
Journal: Immunity
Title: K⁺ efflux is the common trigger of NLRP3 inflammasome activation by bacterial toxins and particulate matter.
Volume: 38
Issue: 6
Pages: 1142-53
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Publication
34861190 | J:331916
First Author: Andreeva L
Year: 2021
Journal: Cell
Title: NLRP3 cages revealed by full-length mouse NLRP3 structure control pathway activation.
Volume: 184
Issue: 26
Pages: 6299-6312.e22
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Publication
32246016 | J:287098
First Author: Hamarsheh S
Year: 2020
Journal: Nat Commun
Title: Oncogenic KrasG12D causes myeloproliferation via NLRP3 inflammasome activation.
Volume: 11
Issue: 1
Pages: 1659
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Publication
19501001 | J:150053
First Author: Meng G
Year: 2009
Journal: Immunity
Title: A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses.
Volume: 30
Issue: 6
Pages: 860-74
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Publication
22461501 | J:183942
First Author: Shenoy AR
Year: 2012
Journal: Science
Title: GBP5 promotes NLRP3 inflammasome assembly and immunity in mammals.
Volume: 336
Issue: 6080
Pages: 481-5
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Publication
33523841 | J:307619
 
First Author: Navarro-Pando JM
Year: 2021
Journal: Sci Adv
Title: Inhibition of the NLRP3 inflammasome prevents ovarian aging.
Volume: 7
Issue: 1
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Publication
21124315 | J:168710
First Author: Zhou R
Year: 2011
Journal: Nature
Title: A role for mitochondria in NLRP3 inflammasome activation.
Volume: 469
Issue: 7329
Pages: 221-5
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Publication
28039299 | J:247871
First Author: Lu A
Year: 2017
Journal: J Immunol
Title: Hyperactivation of the NLRP3 Inflammasome in Myeloid Cells Leads to Severe Organ Damage in Experimental Lupus.
Volume: 198
Issue: 3
Pages: 1119-1129
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Allele
Nlrp3<tm2.1(NLRP3)Bhk> | MGI:5910169
Name: NLR family, pyrin domain containing 3; targeted mutation 2.1, Beverly H Koller
Allele Type: Targeted
Attribute String: Humanized sequence, Inserted expressed sequence, No functional change, Null/knockout
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Publication
25477279 | J:269822
First Author: Qu C
Year: 2015
Journal: FASEB J
Title: NLRP3 mediates osteolysis through inflammation-dependent and -independent mechanisms.
Volume: 29
Issue: 4
Pages: 1269-79
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Publication
35779608 | J:337222
First Author: Shahzad K
Year: 2022
Journal: Kidney Int
Title: Podocyte-specific Nlrp3 inflammasome activation promotes diabetic kidney disease.
Volume: 102
Issue: 4
Pages: 766-779
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Publication
31379826 | J:284456
 
First Author: Sokolova M
Year: 2019
Journal: Front Immunol
Title: NLRP3 Inflammasome Promotes Myocardial Remodeling During Diet-Induced Obesity.
Volume: 10
Pages: 1621
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Publication
23260196 | J:192616
First Author: Kang TB
Year: 2013
Journal: Immunity
Title: Caspase-8 blocks kinase RIPK3-mediated activation of the NLRP3 inflammasome.
Volume: 38
Issue: 1
Pages: 27-40
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Publication
27779186 | J:242646
 
First Author: Xie M
Year: 2016
Journal: Nat Commun
Title: PKM2-dependent glycolysis promotes NLRP3 and AIM2 inflammasome activation.
Volume: 7
Pages: 13280
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Publication
24012762 | J:202838
First Author: Marneros AG
Year: 2013
Journal: Cell Rep
Title: NLRP3 inflammasome blockade inhibits VEGF-A-induced age-related macular degeneration.
Volume: 4
Issue: 5
Pages: 945-58
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Publication
22342844 | J:187340
First Author: Shimada K
Year: 2012
Journal: Immunity
Title: Oxidized mitochondrial DNA activates the NLRP3 inflammasome during apoptosis.
Volume: 36
Issue: 3
Pages: 401-14
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Publication
23100513 | J:190677
First Author: Hernandez-Cuellar E
Year: 2012
Journal: J Immunol
Title: Cutting edge: nitric oxide inhibits the NLRP3 inflammasome.
Volume: 189
Issue: 11
Pages: 5113-7
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Publication
25594175 | J:219265
First Author: Yan Y
Year: 2015
Journal: Cell
Title: Dopamine controls systemic inflammation through inhibition of NLRP3 inflammasome.
Volume: 160
Issue: 1-2
Pages: 62-73
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Publication
33247121 | J:299825
First Author: Song H
Year: 2020
Journal: Nat Commun
Title: UAF1 deubiquitinase complexes facilitate NLRP3 inflammasome activation by promoting NLRP3 expression.
Volume: 11
Issue: 1
Pages: 6042
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Publication
23246432 | J:331359
First Author: Py BF
Year: 2013
Journal: Mol Cell
Title: Deubiquitination of NLRP3 by BRCC3 critically regulates inflammasome activity.
Volume: 49
Issue: 2
Pages: 331-8
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Publication
28716882 | J:244223
First Author: Zhang Z
Year: 2017
Journal: J Exp Med
Title: Protein kinase D at the Golgi controls NLRP3 inflammasome activation.
Volume: 214
Issue: 9
Pages: 2671-2693
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Publication
34554188 | J:331919
 
First Author: Bittner ZA
Year: 2021
Journal: J Exp Med
Title: BTK operates a phospho-tyrosine switch to regulate NLRP3 inflammasome activity.
Volume: 218
Issue: 11
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Publication
31055218 | J:293634
 
First Author: Niu J
Year: 2019
Journal: Cytokine
Title: Hyperactivation of the NLRP3 inflammasome protects mice against influenza A virus infection via IL-1β mediated neutrophil recruitment.
Volume: 120
Pages: 115-124
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Publication
22531249 | J:316001
First Author: Kuipers MT
Year: 2012
Journal: Anesthesiology
Title: Ventilator-induced lung injury is mediated by the NLRP3 inflammasome.
Volume: 116
Issue: 5
Pages: 1104-15
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Publication
30046112 | J:265305
First Author: Zhong Z
Year: 2018
Journal: Nature
Title: New mitochondrial DNA synthesis enables NLRP3 inflammasome activation.
Volume: 560
Issue: 7717
Pages: 198-203
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Publication
29694887 | J:270898
First Author: Alhallaf R
Year: 2018
Journal: Cell Rep
Title: The NLRP3 Inflammasome Suppresses Protective Immunity to Gastrointestinal Helminth Infection.
Volume: 23
Issue: 4
Pages: 1085-1098
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Publication
31270454 | J:288203
First Author: Shimizu H
Year: 2019
Journal: Sci Rep
Title: Pro-inflammatory role of NLRP3 inflammasome in experimental sterile corneal inflammation.
Volume: 9
Issue: 1
Pages: 9596
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Publication
34341353 | J:313326
First Author: Pan P
Year: 2021
Journal: Nat Commun
Title: SARS-CoV-2 N protein promotes NLRP3 inflammasome activation to induce hyperinflammation.
Volume: 12
Issue: 1
Pages: 4664
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Publication
19950187 | J:157782
First Author: Reimer T
Year: 2010
Journal: Eur J Immunol
Title: Experimental cerebral malaria progresses independently of the Nlrp3 inflammasome.
Volume: 40
Issue: 3
Pages: 764-9
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Publication
27974218 | J:241705
First Author: Snouwaert JN
Year: 2016
Journal: Cell Rep
Title: An NLRP3 Mutation Causes Arthropathy and Osteoporosis in Humanized Mice.
Volume: 17
Issue: 11
Pages: 3077-3088
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Publication
34745110 | J:315834
 
First Author: Zhang X
Year: 2021
Journal: Front Immunol
Title: Erianin: A Direct NLRP3 Inhibitor With Remarkable Anti-Inflammatory Activity.
Volume: 12
Pages: 739953
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Publication
34615873 | J:313659
First Author: Niu T
Year: 2021
Journal: Nat Commun
Title: NLRP3 phosphorylation in its LRR domain critically regulates inflammasome assembly.
Volume: 12
Issue: 1
Pages: 5862
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Publication
23582325 | J:197368
First Author: Subramanian N
Year: 2013
Journal: Cell
Title: The adaptor MAVS promotes NLRP3 mitochondrial localization and inflammasome activation.
Volume: 153
Issue: 2
Pages: 348-61
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Publication
36155655 | J:336980
   
First Author: Cohen H
Year: 2022
Journal: Elife
Title: Post-phagocytosis activation of NLRP3 inflammasome by two novel T6SS effectors.
Volume: 11
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Publication
23264657 | J:192607
First Author: Wang W
Year: 2013
Journal: J Immunol
Title: Inflammasome-independent NLRP3 augments TGF-β signaling in kidney epithelium.
Volume: 190
Issue: 3
Pages: 1239-49
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Publication
28739881 | J:250118
First Author: Xing Y
Year: 2017
Journal: J Immunol
Title: Cutting Edge: TRAF6 Mediates TLR/IL-1R Signaling-Induced Nontranscriptional Priming of the NLRP3 Inflammasome.
Volume: 199
Issue: 5
Pages: 1561-1566
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Publication
28943315 | J:251887
First Author: Song N
Year: 2017
Journal: Mol Cell
Title: NLRP3 Phosphorylation Is an Essential Priming Event for Inflammasome Activation.
Volume: 68
Issue: 1
Pages: 185-197.e6
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Publication
27043286 | J:234957
First Author: Spalinger MR
Year: 2016
Journal: J Clin Invest
Title: NLRP3 tyrosine phosphorylation is controlled by protein tyrosine phosphatase PTPN22.
Volume: 126
Issue: 5
Pages: 1783-800
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Publication
29531021 | J:262083
 
First Author: Huang Y
Year: 2018
Journal: EMBO Mol Med
Title: Tranilast directly targets NLRP3 to treat inflammasome-driven diseases.
Volume: 10
Issue: 4
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Publication
25637014 | J:296049
First Author: Gurung P
Year: 2015
Journal: J Immunol
Title: Cutting edge: SHARPIN is required for optimal NLRP3 inflammasome activation.
Volume: 194
Issue: 5
Pages: 2064-7
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Publication
36288697 | J:330955
First Author: Li S
Year: 2022
Journal: Cell Rep
Title: Microglial NLRP3 inflammasome activates neurotoxic astrocytes in depression-like mice.
Volume: 41
Issue: 4
Pages: 111532
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Publication
22832107 | J:277584
First Author: Youm YH
Year: 2012
Journal: Cell Rep
Title: The Nlrp3 inflammasome promotes age-related thymic demise and immunosenescence.
Volume: 1
Issue: 1
Pages: 56-68
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Publication
31597697 | J:282842
First Author: Park SH
Year: 2019
Journal: J Biol Chem
Title: NLRP3 negatively regulates Treg differentiation through Kpna2-mediated nuclear translocation.
Volume: 294
Issue: 47
Pages: 17951-17961
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Publication
22569257 | J:184513
First Author: Qiao Y
Year: 2012
Journal: FEBS Lett
Title: TLR-induced NF-κB activation regulates NLRP3 expression in murine macrophages.
Volume: 586
Issue: 7
Pages: 1022-6
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Publication
29907661 | J:265866
First Author: Walenta L
Year: 2018
Journal: Reproduction
Title: NLRP3 in somatic non-immune cells of rodent and primate testes.
Volume: 156
Issue: 3
Pages: 231-238
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Publication
29981343 | J:289718
 
First Author: Curtiss E
Year: 2018
Journal: Exp Eye Res
Title: miR15a regulates NLRP3 inflammasome proteins in the retinal vasculature.
Volume: 176
Pages: 98-102
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Publication
30098377 | J:273237
 
First Author: Wu M
Year: 2018
Journal: Mol Cell Endocrinol
Title: NLRP3 deficiency ameliorates renal inflammation and fibrosis in diabetic mice.
Volume: 478
Pages: 115-125
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Publication
20688930 | J:185911
First Author: Vilaysane A
Year: 2010
Journal: J Am Soc Nephrol
Title: The NLRP3 inflammasome promotes renal inflammation and contributes to CKD.
Volume: 21
Issue: 10
Pages: 1732-44
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Publication
34952919 | J:329139
First Author: Yalcinkaya M
Year: 2021
Journal: Sci Rep
Title: Modulation of the NLRP3 inflammasome by Sars-CoV-2 Envelope protein.
Volume: 11
Issue: 1
Pages: 24432
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Publication
33628380 | J:325246
 
First Author: Chen Y
Year: 2021
Journal: Oxid Med Cell Longev
Title: Nlrp3 Deficiency Alleviates Angiotensin II-Induced Cardiomyopathy by Inhibiting Mitochondrial Dysfunction.
Volume: 2021
Pages: 6679100
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Publication
28052869 | J:283136
First Author: Bai M
Year: 2017
Journal: Am J Physiol Renal Physiol
Title: NLRP3 inflammasome activation contributes to aldosterone-induced podocyte injury.
Volume: 312
Issue: 4
Pages: F556-F564
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Publication
35281020 | J:321956
 
First Author: Cheat B
Year: 2022
Journal: Front Immunol
Title: NLRP3 Is Involved in Neutrophil Mobilization in Experimental Periodontitis.
Volume: 13
Pages: 839929
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Publication
22986739 | J:192888
First Author: Chow MT
Year: 2012
Journal: Cancer Res
Title: NLRP3 suppresses NK cell-mediated responses to carcinogen-induced tumors and metastases.
Volume: 72
Issue: 22
Pages: 5721-32
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Publication
27214553 | J:237067
First Author: Waldhuber A
Year: 2016
Journal: J Clin Invest
Title: Uropathogenic Escherichia coli strain CFT073 disrupts NLRP3 inflammasome activation.
Volume: 126
Issue: 7
Pages: 2425-36
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Publication
28942141 | J:250870
First Author: Lee DW
Year: 2017
Journal: Biochem Biophys Res Commun
Title: Carbon monoxide regulates glycolysis-dependent NLRP3 inflammasome activation in macrophages.
Volume: 493
Issue: 2
Pages: 957-963
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Publication
33041005 | J:304018
First Author: Zhang W
Year: 2020
Journal: Biochem Biophys Res Commun
Title: NLRP3 is dispensable for d-galactosamine/lipopolysaccharide-induced acute liver failure.
Volume: 533
Issue: 4
Pages: 1184-1190
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Publication
27256568 | J:319214
First Author: Yeon SH
Year: 2017
Journal: J Leukoc Biol
Title: Oxidized phosphatidylcholine induces the activation of NLRP3 inflammasome in macrophages.
Volume: 101
Issue: 1
Pages: 205-215
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Publication
26683666 | J:229681
First Author: Haque S
Year: 2016
Journal: Am J Pathol
Title: HIV Promotes NLRP3 Inflammasome Complex Activation in Murine HIV-Associated Nephropathy.
Volume: 186
Issue: 2
Pages: 347-58
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Publication
23636457 | J:204023
First Author: Fukumoto J
Year: 2013
Journal: Am J Physiol Cell Physiol
Title: NLRP3 deletion protects from hyperoxia-induced acute lung injury.
Volume: 305
Issue: 2
Pages: C182-9
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Publication
28684277 | J:249785
 
First Author: Zhang Z
Year: 2017
Journal: Neuroscience
Title: NLRP3 inflammasome activation mediates fatigue-like behaviors in mice via neuroinflammation.
Volume: 358
Pages: 115-123
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Publication
29959312 | J:333996
First Author: He H
Year: 2018
Journal: Nat Commun
Title: Oridonin is a covalent NLRP3 inhibitor with strong anti-inflammasome activity.
Volume: 9
Issue: 1
Pages: 2550
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Publication
28249154 | J:265972
First Author: Goldberg EL
Year: 2017
Journal: Cell Rep
Title: β-Hydroxybutyrate Deactivates Neutrophil NLRP3 Inflammasome to Relieve Gout Flares.
Volume: 18
Issue: 9
Pages: 2077-2087
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Publication
29884801 | J:266100
First Author: Lang T
Year: 2018
Journal: Nat Commun
Title: Macrophage migration inhibitory factor is required for NLRP3 inflammasome activation.
Volume: 9
Issue: 1
Pages: 2223
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Publication
34433035 | J:330772
First Author: Li X
Year: 2021
Journal: Cell Rep
Title: Macrophage HIF-2α suppresses NLRP3 inflammasome activation and alleviates insulin resistance.
Volume: 36
Issue: 8
Pages: 109607
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Publication
30105037 | J:313199
 
First Author: Wang X
Year: 2018
Journal: Front Immunol
Title: NLRP3 Inflammasome Participates in Host Response to Neospora caninum Infection.
Volume: 9
Pages: 1791
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Publication
33358726 | J:300496
 
First Author: Komleva YK
Year: 2021
Journal: Brain Res
Title: NLRP3 deficiency-induced hippocampal dysfunction and anxiety-like behavior in mice.
Volume: 1752
Pages: 147220
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Publication
31453709 | J:281578
First Author: Vinaik R
Year: 2019
Journal: Am J Physiol Endocrinol Metab
Title: NLRP3 inflammasome mediates white adipose tissue browning after burn.
Volume: 317
Issue: 5
Pages: E751-E759
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Publication
33523143 | J:331131
First Author: Scott L Jr
Year: 2021
Journal: Cardiovasc Res
Title: NLRP3 inflammasome is a key driver of obesity-induced atrial arrhythmias.
Volume: 117
Issue: 7
Pages: 1746-1759
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Publication
33963043 | J:321736
First Author: Wang W
Year: 2021
Journal: J Immunol
Title: Galectin-9 Targets NLRP3 for Autophagic Degradation to Limit Inflammation.
Volume: 206
Issue: 11
Pages: 2692-2699
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Publication
27006116 | J:247280
First Author: Suresh R
Year: 2016
Journal: J Cell Sci
Title: Complement-mediated 'bystander' damage initiates host NLRP3 inflammasome activation.
Volume: 129
Issue: 9
Pages: 1928-39
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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