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Search results 1 to 99 out of 99 for Nlrx1

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
79671 | NLRX1
Type: gene
Organism: human
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Gene
100489572 | nlrx1
Type: gene
Organism: frog, western clawed
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Gene
315599 | Nlrx1
Type: gene
Organism: rat
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Gene
489370 | NLRX1
Type: gene
Organism: dog, domestic
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Gene
451605 | NLRX1
Type: gene
Organism: chimpanzee
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Gene
539974 | NLRX1
Type: gene
Organism: cattle
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Gene
419755 | NLRX1
Type: gene
Organism: chicken
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Gene
557335 | nlrx1
Type: gene
Organism: zebrafish
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Gene
703981 | NLRX1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2429611 | Nlrx1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
23212541 | J:257411
First Author: Soares F
Year: 2013
Journal: Innate Immun
Title: NLRX1 does not inhibit MAVS-dependent antiviral signalling.
Volume: 19
Issue: 4
Pages: 438-48
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Publication
25938787 | J:222965
First Author: Kang MJ
Year: 2015
Journal: J Clin Invest
Title: Suppression of NLRX1 in chronic obstructive pulmonary disease.
Volume: 125
Issue: 6
Pages: 2458-62
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Publication
28159898 | J:247870
First Author: Leber A
Year: 2017
Journal: J Immunol
Title: NLRX1 Regulates Effector and Metabolic Functions of CD4+ T Cells.
Volume: 198
Issue: 6
Pages: 2260-2268
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Publication
31052241 | J:289721
 
First Author: Mahmoud S
Year: 2019
Journal: Cells
Title: NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes.
Volume: 8
Issue: 5
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Publication
30191480 | J:321855
First Author: Killackey SA
Year: 2019
Journal: Mol Cell Biochem
Title: The mitochondrial Nod-like receptor NLRX1 modifies apoptosis through SARM1.
Volume: 453
Issue: 1-2
Pages: 187-196
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Publication
32956405 | J:297185
First Author: Kastelberg B
Year: 2020
Journal: PLoS Pathog
Title: NLRX1 is a key regulator of immune signaling during invasive pulmonary aspergillosis.
Volume: 16
Issue: 9
Pages: e1008854
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Publication
33362773 | J:341836
 
First Author: Zhang H
Year: 2020
Journal: Front Immunol
Title: NLRX1 Deletion Increases Ischemia-Reperfusion Damage and Activates Glucose Metabolism in Mouse Heart.
Volume: 11
Pages: 591815
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Publication
38201227 | J:349293
 
First Author: Liu Y
Year: 2023
Journal: Cells
Title: NLRX1 Prevents M2 Macrophage Polarization and Excessive Renal Fibrosis in Chronic Obstructive Nephropathy.
Volume: 13
Issue: 1
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Publication
28626071 | J:244145
First Author: Stokman G
Year: 2017
Journal: J Exp Med
Title: NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity.
Volume: 214
Issue: 8
Pages: 2405-2420
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Publication
21703540 | J:173995
First Author: Allen IC
Year: 2011
Journal: Immunity
Title: NLRX1 protein attenuates inflammatory responses to infection by interfering with the RIG-I-MAVS and TRAF6-NF-κB signaling pathways.
Volume: 34
Issue: 6
Pages: 854-65
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Publication
28967880 | J:258696
First Author: Feng H
Year: 2017
Journal: Nat Immunol
Title: NLRX1 promotes immediate IRF1-directed antiviral responses by limiting dsRNA-activated translational inhibition mediated by PKR.
Volume: 18
Issue: 12
Pages: 1299-1309
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Publication
27105514 | J:309019
First Author: Coutermarsh-Ott S
Year: 2016
Journal: Oncotarget
Title: NLRX1 suppresses tumorigenesis and attenuates histiocytic sarcoma through the negative regulation of NF-κB signaling.
Volume: 7
Issue: 22
Pages: 33096-110
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Publication
35752171 | J:327621
First Author: Killackey SA
Year: 2022
Journal: Mol Cell
Title: Mitochondrial protein import stress regulates the LC3 lipidation step of mitophagy through NLRX1 and RRBP1.
Volume: 82
Issue: 15
Pages: 2815-2831.e5
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Publication
31525189 | J:287790
First Author: Gharagozloo M
Year: 2019
Journal: PLoS Biol
Title: NLRX1 inhibits the early stages of CNS inflammation and prevents the onset of spontaneous autoimmunity.
Volume: 17
Issue: 9
Pages: e3000451
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Publication
36859435 | J:352749
First Author: Kim HR
Year: 2023
Journal: Sci Rep
Title: NLRX1 knockdown attenuates pro-apoptotic signaling and cell death in pulmonary hyperoxic acute injury.
Volume: 13
Issue: 1
Pages: 3441
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Publication
28993512 | J:251380
First Author: Theus MH
Year: 2017
Journal: J Immunol
Title: Loss of NLRX1 Exacerbates Neural Tissue Damage and NF-κB Signaling following Brain Injury.
Volume: 199
Issue: 10
Pages: 3547-3558
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Publication
26367386 | J:243184
First Author: Philipson CW
Year: 2015
Journal: PLoS One
Title: Modeling the Regulatory Mechanisms by Which NLRX1 Modulates Innate Immune Responses to Helicobacter pylori Infection.
Volume: 10
Issue: 9
Pages: e0137839
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Publication
30559741 | J:313190
 
First Author: Huang JH
Year: 2018
Journal: Front Immunol
Title: NLRX1 Facilitates Histoplasma capsulatum-Induced LC3-Associated Phagocytosis for Cytokine Production in Macrophages.
Volume: 9
Pages: 2761
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Publication
21703539 | J:173996
First Author: Xia X
Year: 2011
Journal: Immunity
Title: NLRX1 negatively regulates TLR-induced NF-κB signaling by targeting TRAF6 and IKK.
Volume: 34
Issue: 6
Pages: 843-53
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Publication
26971996 | J:234719
First Author: Tattoli I
Year: 2016
Journal: Cell Rep
Title: NLRX1 Acts as an Epithelial-Intrinsic Tumor Suppressor through the Modulation of TNF-Mediated Proliferation.
Volume: 14
Issue: 11
Pages: 2576-86
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Publication
24366868 | J:210371
First Author: Eitas TK
Year: 2014
Journal: J Biol Chem
Title: The nucleotide-binding leucine-rich repeat (NLR) family member NLRX1 mediates protection against experimental autoimmune encephalomyelitis and represses macrophage/microglia-induced inflammation.
Volume: 289
Issue: 7
Pages: 4173-9
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Publication
22749352 | J:187408
First Author: Lei Y
Year: 2012
Journal: Immunity
Title: The mitochondrial proteins NLRX1 and TUFM form a complex that regulates type I interferon and autophagy.
Volume: 36
Issue: 6
Pages: 933-46
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Publication
24799673 | J:211056
First Author: Jaworska J
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: NLRX1 prevents mitochondrial induced apoptosis and enhances macrophage antiviral immunity by interacting with influenza virus PB1-F2 protein.
Volume: 111
Issue: 20
Pages: E2110-9
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Publication
26971998 | J:234718
First Author: Koblansky AA
Year: 2016
Journal: Cell Rep
Title: The Innate Immune Receptor NLRX1 Functions as a Tumor Suppressor by Reducing Colon Tumorigenesis and Key Tumor-Promoting Signals.
Volume: 14
Issue: 11
Pages: 2562-75
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Publication
30908533 | J:274769
First Author: Scantlebery AML
Year: 2019
Journal: PLoS One
Title: NLRX1 does not play a role in diabetes nor the development of diabetic nephropathy induced by multiple low doses of streptozotocin.
Volume: 14
Issue: 3
Pages: e0214437
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Publication
34087956 | J:310503
First Author: Shin HJ
Year: 2021
Journal: Aging Cell
Title: Nucleotide-binding domain and leucine-rich-repeat-containing protein X1 deficiency induces nicotinamide adenine dinucleotide decline, mechanistic target of rapamycin activation, and cellular senescence and accelerates aging lung-like changes.
Volume: 20
Issue: 7
Pages: e13410
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Publication
37909827 | J:343876
First Author: Nagai-Singer MA
Year: 2023
Journal: J Immunol
Title: Cellular Context Dictates the Suppression or Augmentation of Triple-Negative Mammary Tumor Metastasis by NLRX1.
Volume: 211
Issue: 12
Pages: 1844-1857
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Publication
35651602 | J:325689
 
First Author: Snäkä T
Year: 2022
Journal: Front Immunol
Title: Sex-Biased Control of Inflammation and Metabolism by a Mitochondrial Nod-Like Receptor.
Volume: 13
Pages: 882867
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Publication
30804553 | J:282400
First Author: Zhang Y
Year: 2019
Journal: Nat Immunol
Title: Listeria hijacks host mitophagy through a novel mitophagy receptor to evade killing.
Volume: 20
Issue: 4
Pages: 433-446
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Publication
35283725 | J:327259
 
First Author: Fritsch LE
Year: 2022
Journal: Front Mol Neurosci
Title: Type I Interferon Response Is Mediated by NLRX1-cGAS-STING Signaling in Brain Injury.
Volume: 15
Pages: 852243
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Protein Coding Gene
MGP_CAROLIEiJ_G0032105 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034697 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034678 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034604 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034669 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034380 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2429611 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035190 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033702 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0034511 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034452 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034592 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0034496 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035211 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033408 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033815 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0014974 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033242 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21617692 | J:203095
First Author: Rebsamen M
Year: 2011
Journal: Cell Death Differ
Title: NLRX1/NOD5 deficiency does not affect MAVS signalling.
Volume: 18
Issue: 8
Pages: 1387
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Publication
18341998 | J:132935
First Author: Ting JP
Year: 2008
Journal: Immunity
Title: The NLR gene family: a standard nomenclature.
Volume: 28
Issue: 3
Pages: 285-7
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GXD Expression
GXD Expression
   
Probe: MGI:3149484
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526610
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3149484
Assay Type: RNA in situ
Annotation Date: 2023-09-18
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7526610
Age: embryonic day 14.5
Note: Ventricular zone expression was greater than in the cortical plate.
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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Publication
26320999 | J:243015
First Author: Aachoui Y
Year: 2015
Journal: Cell Host Microbe
Title: Canonical Inflammasomes Drive IFN-γ to Prime Caspase-11 in Defense against a Cytosol-Invasive Bacterium.
Volume: 18
Issue: 3
Pages: 320-32
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Publication
12140190 | J:78123
First Author: Kameya S
Year: 2002
Journal: Hum Mol Genet
Title: Mfrp, a gene encoding a frizzled related protein, is mutated in the mouse retinal degeneration 6.
Volume: 11
Issue: 16
Pages: 1879-86
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:82809
     
First Author: European Mouse Mutant Archive
Year: 2003
Journal: Unpublished
Title: Information obtained from the European Mouse Mutant Archive (EMMA)
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q3UEY2
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
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Allele
Nlrx1<em1Smoc> | MGI:7291332
Name: NLR family member X1; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Interaction Experiment
Xia X (2011)
Description: NLRX1 negatively regulates TLR-induced NF-B signaling by targeting TRAF6 and IKK.
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Strain
MGI:6475884 | C57BL/6JSmoc-Nlrx1<em1Smoc>/Smoc
Attribute String: coisogenic, endonuclease-mediated mutation, mutant strain
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Publication
28542569 | J:245551
First Author: Kim JH
Year: 2017
Journal: PLoS Pathog
Title: FAS-associated factor-1 positively regulates type I interferon response to RNA virus infection by targeting NLRX1.
Volume: 13
Issue: 5
Pages: e1006398
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Publication
24872587 | J:296325
First Author: Lupfer C
Year: 2014
Journal: J Virol
Title: Nucleotide oligomerization and binding domain 2-dependent dendritic cell activation is necessary for innate immunity and optimal CD8+ T Cell responses to influenza A virus infection.
Volume: 88
Issue: 16
Pages: 8946-55
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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