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Search results 1 to 100 out of 113 for Nms

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Hits by Pathway

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Hits by Category

Type Details Score
Gene
129521 | NMS
Type: gene
Organism: human
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Gene
768331 | NMS
Type: gene
Organism: cattle
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Gene
100272161 | nms
Type: gene
Organism: zebrafish
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Gene
710021 | NMS
Type: gene
Organism: macaque, rhesus
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Gene
101750419 | NMS
Type: gene
Organism: chicken
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Gene
116408866 | nms
Type: gene
Organism: frog, western clawed
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Gene
497196 | NMS
Type: gene
Organism: rat
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Gene
474554 | NMS
Type: gene
Organism: dog, domestic
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Gene
743340 | NMS
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:3583618 | Nms
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR043253 | NmS
Type: Family
Description: Neuromedin S (NmS) is a neuromedin U-related peptide. It has shown to possess anorexigenic and circadian rhythm-modulating properties in mammals. NmS expression is localised predominantly in the core region of the suprachiasmatic nucleus within the hypothalamus, but also in spleen and testis []. Other biological functions include antidiuretic action via release of vasopressin, milk ejection via release of oxytocin and regulation of the circulatory system, immune reactions and insulin secretion. NmU (neuromedin U) and NmS are involved in thermoregulation via the sympathetic nervous system (beta3 adrenergic receptors) and prostaglandin E2 [].
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Publication
26826380 | J:233329
First Author: Nakahara K
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Involvement of endogenous neuromedin U and neuromedin S in thermoregulation.
Volume: 470
Issue: 4
Pages: 930-5
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Publication
16682011 | -
First Author: Chen T
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Structural and functional analogs of the novel mammalian neuropeptide, neuromedin S (NmS), in the dermal venoms of Eurasian bombinid toads.
Volume: 345
Issue: 1
Pages: 377-84
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Protein
Q5H8A1
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
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Protein
A0A250SH12
Organism: Mus musculus/domesticus
Length: 153  
Fragment?: false
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Protein
E0CXN4
Organism: Mus musculus/domesticus
Length: 138  
Fragment?: true
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Publication
25741729 | J:219926
First Author: Lee IT
Year: 2015
Journal: Neuron
Title: Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms.
Volume: 85
Issue: 5
Pages: 1086-102
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Publication
21356261 | J:309890
First Author: Sakamoto T
Year: 2011
Journal: Peptides
Title: Neuromedin S regulates cardiovascular function through the sympathetic nervous system in mice.
Volume: 32
Issue: 5
Pages: 1020-6
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Publication
15635449 | J:98692
First Author: Mori K
Year: 2005
Journal: EMBO J
Title: Identification of neuromedin S and its possible role in the mammalian circadian oscillator system.
Volume: 24
Issue: 2
Pages: 325-35
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Protein Coding Gene
MGP_CAROLIEiJ_G0014066 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0015953 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0015937 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0015892 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0015891 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0015724 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_3583618 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0016344 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0015305 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0015696 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0015797 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0015799 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0015867 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0015819 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0016391 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0015088 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0015367 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0027313 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0014870 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
19549882 | J:151893
First Author: Novak CM
Year: 2009
Journal: Endocrinology
Title: Neuromedin S and U.
Volume: 150
Issue: 7
Pages: 2985-7
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Publication
35908898 | J:334845
First Author: Yamaguchi Y
Year: 2022
Journal: Biol Pharm Bull
Title: Nmu/Nms/Gpr176 Triple-Deficient Mice Show Enhanced Light-Resetting of Circadian Locomotor Activity.
Volume: 45
Issue: 8
Pages: 1172-1179
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Publication
35008655 | J:317412
 
First Author: Cheng AH
Year: 2021
Journal: Int J Mol Sci
Title: SOX2 Regulates Neuronal Differentiation of the Suprachiasmatic Nucleus.
Volume: 23
Issue: 1
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Publication
33238113 | J:298882
First Author: Roome RB
Year: 2020
Journal: Cell Rep
Title: Phox2a Defines a Developmental Origin of the Anterolateral System in Mice and Humans.
Volume: 33
Issue: 8
Pages: 108425
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Publication
- | J:238766
     
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
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Publication
- | J:104881
     
First Author: The RIKEN BioResource Center
Year: 2006
Journal: Unpublished
Title: Information obtained from The RIKEN BioResource Center
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Publication
- | J:81858
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: Data Curation Using Mouse Genome Assembly
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Publication
- | J:136110
     
First Author: Velocigene
Year: 2008
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals)
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155845
     
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Author
Dos Santos NMS
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GO Term
GO:0090234 | regulation of kinetochore assembly
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Allele
Nms<em1Smoc> | MGI:7291340
Name: neuromedin S; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
31227743 | J:297129
First Author: Rodrigues IS
Year: 2019
Journal: Sci Rep
Title: Involvement of Hsp90 and cyclophilins in intoxication by AIP56, a metalloprotease toxin from Photobacterium damselae subsp. piscicida.
Volume: 9
Issue: 1
Pages: 9019
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GO Term
GO:0000776 | kinetochore
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GO Term
GO:0051382 | kinetochore assembly
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Allele
Tg(Nms-icre)20Ywa | MGI:5638418
Name: transgene insertion 20, Masashi Yanagisawa
Allele Type: Transgenic
Attribute String: Recombinase
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Strain
MGI:5638421 | C57BL/6-Tg(Nms-icre)20Ywa/J
Attribute String: coisogenic, mutant strain, transgenic
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Publication
35521538 | J:328751
First Author: Zhai Q
Year: 2022
Journal: iScience
Title: Time-restricted feeding entrains long-term behavioral changes through the IGF2-KCC2 pathway.
Volume: 25
Issue: 5
Pages: 104267
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Allele
Tg(Nms-EGFP)GQ216Gsat | MGI:4847263
Name: transgene insertion GQ216, GENSAT Project at Rockefeller University
Allele Type: Transgenic
Attribute String: Reporter
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Strain
MGI:5003630 | STOCK Tg(Nms-EGFP)GQ216Gsat/Mmucd
Attribute String: mutant stock, transgenic
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Strain
MGI:5659422 | B6.Cg-Gt(ROSA)26Sor<tm1(EYFP)Cos> Tg(Nms-icre)20Ywa
Attribute String: transgenic, mutant strain, gene trap
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Genotype
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Tg(Nms-icre)20Ywa/?
Background: B6.Cg-Gt(ROSA)26Sor Tg(Nms-icre)20Ywa
Zygosity: cn
Has Mutant Allele: true
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Protein
Q8K305
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
E9QME3
Organism: Mus musculus/domesticus
Length: 281  
Fragment?: false
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Protein
Q8CDX2
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Protein
D3Z4S2
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: true
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Protein
E9Q3W6
Organism: Mus musculus/domesticus
Length: 174  
Fragment?: false
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Publication
15371542 | -
First Author: Kerres A
Year: 2004
Journal: Mol Biol Cell
Title: The fission yeast kinetochore component Spc7 associates with the EB1 family member Mal3 and is required for kinetochore-spindle association.
Volume: 15
Issue: 12
Pages: 5255-67
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Publication
15369671 | -
First Author: Hayashi T
Year: 2004
Journal: Cell
Title: Mis16 and Mis18 are required for CENP-A loading and histone deacetylation at centromeres.
Volume: 118
Issue: 6
Pages: 715-29
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Protein Domain
IPR038273 | Ndc80_sf
Type: Homologous_superfamily
Description: This entry represents a domain found in the kinetochore protein Ndc80. Ndc80 acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. It has been shown that Ndc80 from yeast is part of a complex called the Ndc80p complex []. The four Ndc80 complex subunits associate as two rod-like heterodimers (Ndc80:Nuf2 and Spc24:Spc25) []. This complex is thought to bind to the microtubules of the spindle.
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Protein Domain
IPR005550 | Kinetochore_Ndc80
Type: Family
Description: Members of this family are components of the mitotic spindle. Ndc80 acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. It has been shown that Ndc80 from yeast is part of a complex called the Ndc80p complex []. The four Ndc80 complex subunits associate as two rod-like heterodimers (Ndc80:Nuf2 and Spc24:Spc25) []. This complex is thought to bind to the microtubules of the spindle.
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Protein Domain
IPR013253 | Spc7_domain
Type: Domain
Description: This domain is found in cell division proteins which are required for kinetochore-spindle association []. Proteins containing this domain include budding yeast Spc105 and fission yeast Spc7.Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex, which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle []. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [].
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Protein Domain
IPR037475 | Sos7
Type: Family
Description: Attachment of sister chromatids to microtubules in the fission yeast Schizosaccharomyces pombe is mediated by the kinetochore complex NMS (Ndc80-MIND-Spc7). Sos7 is a component of the MIND complex and is required for kinetochore targeting of Spc7 []. This fungal kinetochore family represented by Sos7 is not present in yeasts belonging to the Saccharomyces complex. Instead, these organisms have proteins homologous to the S. cerevisiae Spc105 interaction partner Kre28.
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Protein Domain
IPR013950 | Mis14/Nsl1
Type: Family
Description: This entry includes Mis14 from S. pombe, Nsl1 from S. cerevisiae and Nsl1 homologues from animals. MIs14 is a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle []. Nsl1 is an essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity [].
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Protein Domain
IPR033338 | Spc105/Spc7
Type: Family
Description: This entry includes Spc105 from budding yeasts and Spc7 from fission yeasts. Spc7 is a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle []. Spc105 and Kre28 forms a kinetochore complex, which is required for kinetochore binding by a discrete subset of kMAPs (BIM1, BIK1 and SLK19) and motors (CIN8, KAR3) [].
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Publication
22711988 | -
First Author: Jakopec V
Year: 2012
Journal: Mol Cell Biol
Title: Sos7, an essential component of the conserved Schizosaccharomyces pombe Ndc80-MIND-Spc7 complex, identifies a new family of fungal kinetochore proteins.
Volume: 32
Issue: 16
Pages: 3308-20
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GO Term
GO:1905560 | negative regulation of kinetochore assembly
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GO Term
GO:1905561 | positive regulation of kinetochore assembly
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Protein
Q9CYC5
Organism: Mus musculus/domesticus
Length: 348  
Fragment?: false
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Protein
A2ACV5
Organism: Mus musculus/domesticus
Length: 232  
Fragment?: true
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Protein
B0QZT4
Organism: Mus musculus/domesticus
Length: 124  
Fragment?: true
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Protein Domain
IPR013218 | Dsn1/Mis13
Type: Family
Description: This entry represents the kinetochore-associated protein Dsn1/Mis13.In Saccharomyces cerevisiae, Dsn1 acts as essential component of the kinetochore MIND complex, which is required for the spindle checkpoint and kinetochore integrity. MIND plays a role in establishing a bipolar spindle-kinetochore interaction by joining kinetochore subunits contacting DNA to those contacting microtubules [, ].In Schizosaccharomyces pombe, Mis13 acts as a component of the NMS (Ndc80-MIND-Spc7) super complex which has a role in kinetochore function during late meiotic prophase and throughout the mitotic cell cycle. It is required for correct segregation of chromosomes and for maintaining the inner centromere structure [, ].
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Publication
30597051 | J:340943
First Author: Tinklenberg JA
Year: 2019
Journal: J Neuropathol Exp Neurol
Title: Myostatin Inhibition Using ActRIIB-mFc Does Not Produce Weight Gain or Strength in the Nebulin Conditional KO Mouse.
Volume: 78
Issue: 2
Pages: 130-139
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Protein
Q9D0F1
Organism: Mus musculus/domesticus
Length: 642  
Fragment?: false
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Protein
A0A3B2WAS6
Organism: Mus musculus/domesticus
Length: 629  
Fragment?: false
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Publication
27851957 | -
First Author: Valverde R
Year: 2016
Journal: Cell Rep
Title: Conserved Tetramer Junction in the Kinetochore Ndc80 Complex.
Volume: 17
Issue: 8
Pages: 1915-1922
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Publication
19893618 | -
First Author: Pagliuca C
Year: 2009
Journal: PLoS One
Title: Roles for the conserved spc105p/kre28p complex in kinetochore-microtubule binding and the spindle assembly checkpoint.
Volume: 4
Issue: 10
Pages: e7640
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Publication
17035632 | -
First Author: Hayashi A
Year: 2006
Journal: Mol Biol Cell
Title: Reconstruction of the kinetochore during meiosis in fission yeast Schizosaccharomyces pombe.
Volume: 17
Issue: 12
Pages: 5173-84
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Publication
19324999 | J:152371
First Author: Peier A
Year: 2009
Journal: Endocrinology
Title: The antiobesity effects of centrally administered neuromedin U and neuromedin S are mediated predominantly by the neuromedin U receptor 2 (NMUR2).
Volume: 150
Issue: 7
Pages: 3101-9
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Publication
36359880 | J:331575
 
First Author: Brocca ME
Year: 2022
Journal: Cells
Title: Normal Cortical Myelination in Galectin-4-Deficient Mice.
Volume: 11
Issue: 21
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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