Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active peptides, it is proteolytically processed from a larger precursor protein. The mature peptides are 8 (NmU-8) to 25 (NmU-25) residues long and C-terminally amidated [, ]. |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
166
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Wallrapp A |
Year: |
2017 |
Journal: |
Nature |
Title: |
The neuropeptide NMU amplifies ILC2-driven allergic lung inflammation. |
Volume: |
549 |
Issue: |
7672 |
Pages: |
351-356 |
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson EL |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Chronic administration of NMU into the paraventricular nucleus stimulates the HPA axis but does not influence food intake or body weight. |
Volume: |
323 |
Issue: |
1 |
Pages: |
65-71 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
174
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Domin J |
Year: |
1988 |
Journal: |
Ann N Y Acad Sci |
Title: |
The distribution and biological effects of neuromedins B and U. |
Volume: |
547 |
|
Pages: |
391-403 |
|
•
•
•
•
•
|
Publication |
First Author: |
Domin J |
Year: |
1992 |
Journal: |
Regul Pept |
Title: |
The purification and sequence analysis of an avian neuromedin U. |
Volume: |
41 |
Issue: |
1 |
Pages: |
1-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakahara K |
Year: |
2016 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Involvement of endogenous neuromedin U and neuromedin S in thermoregulation. |
Volume: |
470 |
Issue: |
4 |
Pages: |
930-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Medrano M |
Year: |
2023 |
Journal: |
Open Biol |
Title: |
Neuroanatomical characterization of the Nmu-Cre knock-in mice reveals an interconnected network of unique neuropeptidergic cells. |
Volume: |
13 |
Issue: |
6 |
Pages: |
220353 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fukue Y |
Year: |
2006 |
Journal: |
FEBS Lett |
Title: |
Regulation of gonadotropin secretion and puberty onset by neuromedin U. |
Volume: |
580 |
Issue: |
14 |
Pages: |
3485-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanada R |
Year: |
2004 |
Journal: |
Nat Med |
Title: |
Neuromedin U has a novel anorexigenic effect independent of the leptin signaling pathway. |
Volume: |
10 |
Issue: |
10 |
Pages: |
1067-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Abbondanzo SJ |
Year: |
2009 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Nmur1-/- mice are not protected from cutaneous inflammation. |
Volume: |
378 |
Issue: |
4 |
Pages: |
777-82 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nakahara K |
Year: |
2004 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Neuromedin U is involved in nociceptive reflexes and adaptation to environmental stimuli in mice. |
Volume: |
323 |
Issue: |
2 |
Pages: |
615-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moriyama M |
Year: |
2006 |
Journal: |
Am J Physiol Lung Cell Mol Physiol |
Title: |
The neuropeptide neuromedin U activates eosinophils and is involved in allergen-induced eosinophilia. |
Volume: |
290 |
Issue: |
5 |
Pages: |
L971-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizukawa Y |
Year: |
2016 |
Journal: |
PLoS One |
Title: |
Epidermal Neuromedin U Attenuates IgE-Mediated Allergic Skin Inflammation. |
Volume: |
11 |
Issue: |
7 |
Pages: |
e0160122 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kowalski TJ |
Year: |
2005 |
Journal: |
J Endocrinol |
Title: |
Transgenic overexpression of neuromedin U promotes leanness and hypophagia in mice. |
Volume: |
185 |
Issue: |
1 |
Pages: |
151-64 |
|
•
•
•
•
•
|
Publication |
First Author: |
Prendergast CE |
Year: |
2006 |
Journal: |
Br J Pharmacol |
Title: |
Species-dependent smooth muscle contraction to Neuromedin U and determination of the receptor subtypes mediating contraction using NMU1 receptor knockout mice. |
Volume: |
147 |
Issue: |
8 |
Pages: |
886-96 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bechtold DA |
Year: |
2009 |
Journal: |
Am J Physiol Endocrinol Metab |
Title: |
Appetite-modifying actions of pro-neuromedin U-derived peptides. |
Volume: |
297 |
Issue: |
2 |
Pages: |
E545-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hsiao YT |
Year: |
2020 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Neuromedin U (NMU) regulates osteoblast differentiation and activity. |
Volume: |
524 |
Issue: |
4 |
Pages: |
890-894 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moriyama M |
Year: |
2006 |
Journal: |
Biochem Biophys Res Commun |
Title: |
The neuropeptide neuromedin U promotes IL-6 production from macrophages and endotoxin shock. |
Volume: |
341 |
Issue: |
4 |
Pages: |
1149-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao SM |
Year: |
2012 |
Journal: |
Arthritis Res Ther |
Title: |
The neuropeptide neuromedin U promotes autoantibody-mediated arthritis. |
Volume: |
14 |
Issue: |
1 |
Pages: |
R29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Moriyama M |
Year: |
2005 |
Journal: |
J Exp Med |
Title: |
The neuropeptide neuromedin U promotes inflammation by direct activation of mast cells. |
Volume: |
202 |
Issue: |
2 |
Pages: |
217-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Li Y |
Year: |
2023 |
Journal: |
Science |
Title: |
Neuromedin U programs eosinophils to promote mucosal immunity of the small intestine. |
Volume: |
381 |
Issue: |
6663 |
Pages: |
1189-1196 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sato S |
Year: |
2007 |
Journal: |
Nat Med |
Title: |
Central control of bone remodeling by neuromedin U. |
Volume: |
13 |
Issue: |
10 |
Pages: |
1234-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peier AM |
Year: |
2011 |
Journal: |
Endocrinology |
Title: |
Effects of peripherally administered neuromedin U on energy and glucose homeostasis. |
Volume: |
152 |
Issue: |
7 |
Pages: |
2644-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cardoso V |
Year: |
2017 |
Journal: |
Nature |
Title: |
Neuronal regulation of type 2 innate lymphoid cells via neuromedin U. |
Volume: |
549 |
Issue: |
7671 |
Pages: |
277-281 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691578 |
Age: |
postnatal adult |
Image: |
MRC Harwell_1567219 |
|
Specimen Label: |
MRC Harwell_1567219 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1702128 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691578 |
Age: |
postnatal adult |
Image: |
MRC Harwell_1567220 |
|
Specimen Label: |
MRC Harwell_1567220 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Female |
Emaps: |
EMAPS:1757728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691578 |
Age: |
postnatal adult |
Image: |
MRC Harwell_1567221 |
|
Specimen Label: |
MRC Harwell_1567221 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sharma SK |
Year: |
2000 |
Journal: |
GenBank Submission |
Title: |
Mus musculus neuromedin U precursor (NmU) mRNA, complete cds |
|
|
Pages: |
AF203444 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizuno S |
Year: |
2015 |
Journal: |
Sci Rep |
Title: |
Peri-implantation lethality in mice carrying megabase-scale deletion on 5qc3.3 is caused by Exoc1 null mutation. |
Volume: |
5 |
|
Pages: |
13632 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klose CSN |
Year: |
2017 |
Journal: |
Nature |
Title: |
The neuropeptide neuromedin U stimulates innate lymphoid cells and type 2 inflammation. |
Volume: |
549 |
Issue: |
7671 |
Pages: |
282-286 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sakamoto T |
Year: |
2011 |
Journal: |
Peptides |
Title: |
Neuromedin S regulates cardiovascular function through the sympathetic nervous system in mice. |
Volume: |
32 |
Issue: |
5 |
Pages: |
1020-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Novak CM |
Year: |
2009 |
Journal: |
Endocrinology |
Title: |
Neuromedin S and U. |
Volume: |
150 |
Issue: |
7 |
Pages: |
2985-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori K |
Year: |
2005 |
Journal: |
EMBO J |
Title: |
Identification of neuromedin S and its possible role in the mammalian circadian oscillator system. |
Volume: |
24 |
Issue: |
2 |
Pages: |
325-35 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yamaguchi Y |
Year: |
2022 |
Journal: |
Biol Pharm Bull |
Title: |
Nmu/Nms/Gpr176 Triple-Deficient Mice Show Enhanced Light-Resetting of Circadian Locomotor Activity. |
Volume: |
45 |
Issue: |
8 |
Pages: |
1172-1179 |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Publication |
First Author: |
Wilsbacher LD |
Year: |
2000 |
Journal: |
Genome Res |
Title: |
The mouse Clock locus: sequence and comparative analysis of 204 kb from mouse chromosome 5. |
Volume: |
10 |
Issue: |
12 |
Pages: |
1928-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doi T |
Year: |
2017 |
Journal: |
J Invest Dermatol |
Title: |
Importance of Water Content of the Stratum Corneum in Mouse Models for Contact Hypersensitivity. |
Volume: |
137 |
Issue: |
1 |
Pages: |
151-158 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee IT |
Year: |
2015 |
Journal: |
Neuron |
Title: |
Neuromedin s-producing neurons act as essential pacemakers in the suprachiasmatic nucleus to couple clock neurons and dictate circadian rhythms. |
Volume: |
85 |
Issue: |
5 |
Pages: |
1086-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Correa SM |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
An estrogen-responsive module in the ventromedial hypothalamus selectively drives sex-specific activity in females. |
Volume: |
10 |
Issue: |
1 |
Pages: |
62-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Morarach K |
Year: |
2021 |
Journal: |
Nat Neurosci |
Title: |
Diversification of molecularly defined myenteric neuron classes revealed by single-cell RNA sequencing. |
Volume: |
24 |
Issue: |
1 |
Pages: |
34-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
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Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
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Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
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Title: |
Cyagen Biosciences Website. |
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Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
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