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Search results 1 to 100 out of 518 for Nod2

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
64127 | NOD2
Type: gene
Organism: human
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Gene
291912 | Nod2
Type: gene
Organism: rat
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Gene
487286 | NOD2
Type: gene
Organism: dog, domestic
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Gene
454083 | NOD2
Type: gene
Organism: chimpanzee
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Gene
444867 | NOD2
Type: gene
Organism: cattle
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Gene
777696 | nod2
Type: gene
Organism: zebrafish
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Gene
695542 | NOD2
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2429397 | Nod2
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q80UH7
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80SY8
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80SY7
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80SV8
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80SS7
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80UH4
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80SZ8
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80UH3
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80UH5
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80UH6
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Protein
Q80UH1
Organism: Mus musculus/domesticus
Length: 1013  
Fragment?: false
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Publication
17403772 | J:122657
First Author: Pan Q
Year: 2007
Journal: J Leukoc Biol
Title: MDP-induced interleukin-1beta processing requires Nod2 and CIAS1/NALP3.
Volume: 82
Issue: 1
Pages: 177-83
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Publication
23213202 | J:193102
First Author: Lipinski S
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: RNAi screening identifies mediators of NOD2 signaling: implications for spatial specificity of MDP recognition.
Volume: 109
Issue: 52
Pages: 21426-31
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Publication
18648508 | J:138239
First Author: Meinzer U
Year: 2008
Journal: PLoS One
Title: Nod2 mediates susceptibility to Yersinia pseudotuberculosis in mice.
Volume: 3
Issue: 7
Pages: e2769
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Publication
27007849 | J:335612
First Author: Keestra-Gounder AM
Year: 2016
Journal: Nature
Title: NOD1 and NOD2 signalling links ER stress with inflammation.
Volume: 532
Issue: 7599
Pages: 394-7
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Publication
35420957 | J:323343
First Author: Gabanyi I
Year: 2022
Journal: Science
Title: Bacterial sensing via neuronal Nod2 regulates appetite and body temperature.
Volume: 376
Issue: 6590
Pages: eabj3986
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Publication
29980664 | J:271466
First Author: Gresnigt MS
Year: 2018
Journal: Nat Commun
Title: Genetic deficiency of NOD2 confers resistance to invasive aspergillosis.
Volume: 9
Issue: 1
Pages: 2636
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Publication
19737867 | J:153357
First Author: Penack O
Year: 2009
Journal: J Exp Med
Title: NOD2 regulates hematopoietic cell function during graft-versus-host disease.
Volume: 206
Issue: 10
Pages: 2101-10
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Publication
28658623 | J:254357
First Author: Udden SMN
Year: 2017
Journal: Cell Rep
Title: NOD2 Suppresses Colorectal Tumorigenesis via Downregulation of the TLR Pathways.
Volume: 19
Issue: 13
Pages: 2756-2770
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Publication
39507249 | J:358171
First Author: Rodrigues E-Lacerda R
Year: 2024
Journal: iScience
Title: NOD2 protects against allergic lung inflammation in obese female mice.
Volume: 27
Issue: 11
Pages: 111130
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Publication
37415975 | J:346959
 
First Author: Chauvin C
Year: 2023
Journal: Front Immunol
Title: NOD2 in monocytes negatively regulates macrophage development through TNFalpha.
Volume: 14
Pages: 1181823
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Publication
33239685 | J:299708
First Author: Gurses SA
Year: 2020
Journal: Sci Rep
Title: Nod2 protects mice from inflammation and obesity-dependent liver cancer.
Volume: 10
Issue: 1
Pages: 20519
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Publication
31480799 | J:293526
 
First Author: Lee C
Year: 2019
Journal: Int J Mol Sci
Title: NOD2 Supports Crypt Survival and Epithelial Regeneration after Radiation-Induced Injury.
Volume: 20
Issue: 17
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Publication
24298015 | J:207083
First Author: Myers ND
Year: 2014
Journal: J Immunol
Title: The role of NOD2 in murine and human melioidosis.
Volume: 192
Issue: 1
Pages: 300-7
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Publication
23109427 | J:192843
First Author: Tigno-Aranjuez JT
Year: 2013
Journal: Mol Cell Biol
Title: A discrete ubiquitin-mediated network regulates the strength of NOD2 signaling.
Volume: 33
Issue: 1
Pages: 146-58
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Publication
33106495 | J:298100
First Author: Napier RJ
Year: 2020
Journal: Nat Commun
Title: T cell-intrinsic role for Nod2 in protection against Th17-mediated uveitis.
Volume: 11
Issue: 1
Pages: 5406
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Publication
30150283 | J:265220
First Author: Napier RJ
Year: 2018
Journal: J Immunol
Title: Nod2 Deficiency Augments Th17 Responses and Exacerbates Autoimmune Arthritis.
Volume: 201
Issue: 7
Pages: 1889-1898
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Publication
21421666 | J:194452
First Author: Rehman A
Year: 2011
Journal: Gut
Title: Nod2 is essential for temporal development of intestinal microbial communities.
Volume: 60
Issue: 10
Pages: 1354-62
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Publication
24082103 | J:201998
First Author: Corridoni D
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Dysregulated NOD2 predisposes SAMP1/YitFc mice to chronic intestinal inflammation.
Volume: 110
Issue: 42
Pages: 16999-7004
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Publication
17705131 | J:124337
First Author: Werts C
Year: 2007
Journal: Eur J Immunol
Title: Nod1 and Nod2 induce CCL5/RANTES through the NF-kappaB pathway.
Volume: 37
Issue: 9
Pages: 2499-508
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Publication
21156799 | J:170396
First Author: Bansal K
Year: 2011
Journal: J Biol Chem
Title: Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation.
Volume: 286
Issue: 7
Pages: 5823-35
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Publication
24695226 | J:210445
First Author: Nakamura N
Year: 2014
Journal: Nature
Title: Endosomes are specialized platforms for bacterial sensing and NOD2 signalling.
Volume: 509
Issue: 7499
Pages: 240-4
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Publication
32289499 | J:294843
First Author: Moltzau Anderson J
Year: 2020
Journal: Cell Mol Gastroenterol Hepatol
Title: NOD2 Influences Trajectories of Intestinal Microbiota Recovery After Antibiotic Perturbation.
Volume: 10
Issue: 2
Pages: 365-389
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Publication
25429073 | J:230689
First Author: Dugan J
Year: 2015
Journal: J Immunol
Title: Blau syndrome-associated Nod2 mutation alters expression of full-length NOD2 and limits responses to muramyl dipeptide in knock-in mice.
Volume: 194
Issue: 1
Pages: 349-57
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Publication
23958879 | J:200979
First Author: Zong J
Year: 2013
Journal: Lab Invest
Title: NOD2 deletion promotes cardiac hypertrophy and fibrosis induced by pressure overload.
Volume: 93
Issue: 10
Pages: 1128-36
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Publication
33431850 | J:301066
First Author: Rochereau N
Year: 2021
Journal: Nat Commun
Title: NOD2 deficiency increases retrograde transport of secretory IgA complexes in Crohn's disease.
Volume: 12
Issue: 1
Pages: 261
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Publication
24163408 | J:207016
First Author: Selvanantham T
Year: 2013
Journal: J Immunol
Title: Nod1 and Nod2 enhance TLR-mediated invariant NKT cell activation during bacterial infection.
Volume: 191
Issue: 11
Pages: 5646-54
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Publication
15692052 | J:96128
First Author: Maeda S
Year: 2005
Journal: Science
Title: Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing.
Volume: 307
Issue: 5710
Pages: 734-8
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Publication
36002575 | J:335673
First Author: Stafford CA
Year: 2022
Journal: Nature
Title: Phosphorylation of muramyl peptides by NAGK is required for NOD2 activation.
Volume: 609
Issue: 7927
Pages: 590-596
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Publication
30774010 | J:295849
First Author: Umiker B
Year: 2019
Journal: Innate Immun
Title: The NLRP3 inflammasome mediates DSS-induced intestinal inflammation in Nod2 knockout mice.
Volume: 25
Issue: 2
Pages: 132-143
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Publication
20091781 | J:167893
First Author: Liu X
Year: 2010
Journal: Glia
Title: NOD2 mediates inflammatory responses of primary murine glia to Streptococcus pneumoniae.
Volume: 58
Issue: 7
Pages: 839-47
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Publication
25666722 | J:232669
First Author: Denou E
Year: 2015
Journal: EMBO Mol Med
Title: Defective NOD2 peptidoglycan sensing promotes diet-induced inflammation, dysbiosis, and insulin resistance.
Volume: 7
Issue: 3
Pages: 259-74
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Publication
22951952 | J:190340
First Author: Campbell L
Year: 2013
Journal: J Pathol
Title: Nod2 deficiency impairs inflammatory and epithelial aspects of the cutaneous wound-healing response.
Volume: 229
Issue: 1
Pages: 121-31
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Publication
21108472 | J:174576
First Author: Berrington WR
Year: 2010
Journal: Eur J Immunol
Title: NOD1 and NOD2 regulation of pulmonary innate immunity to Legionella pneumophila.
Volume: 40
Issue: 12
Pages: 3519-27
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Publication
24384785 | J:324314
First Author: Wang C
Year: 2014
Journal: Autophagy
Title: NOD2 is dispensable for ATG16L1 deficiency-mediated resistance to urinary tract infection.
Volume: 10
Issue: 2
Pages: 331-8
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Publication
20921147 | J:166072
First Author: Geddes K
Year: 2010
Journal: Infect Immun
Title: Nod1 and Nod2 regulation of inflammation in the Salmonella colitis model.
Volume: 78
Issue: 12
Pages: 5107-15
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Publication
24766550 | J:219449
First Author: Jeong YJ
Year: 2014
Journal: Immunology
Title: Nod2 and Rip2 contribute to innate immune responses in mouse neutrophils.
Volume: 143
Issue: 2
Pages: 269-76
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Publication
25423082 | J:225282
First Author: Claes AK
Year: 2014
Journal: PLoS One
Title: Salmonella enterica serovar Typhimurium ΔmsbB triggers exacerbated inflammation in Nod2 deficient mice.
Volume: 9
Issue: 11
Pages: e113645
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Publication
20226841 | J:159903
First Author: Liu X
Year: 2010
Journal: Neurosci Lett
Title: NOD2 contributes to the inflammatory responses of primary murine microglia and astrocytes to Staphylococcus aureus.
Volume: 474
Issue: 2
Pages: 93-8
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Publication
29560100 | J:298181
First Author: Kwon MY
Year: 2018
Journal: Oncotarget
Title: NOD2 deficiency exacerbates hypoxia-induced pulmonary hypertension and enhances pulmonary vascular smooth muscle cell proliferation.
Volume: 9
Issue: 16
Pages: 12671-12681
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Publication
19881508 | J:157739
First Author: Shaw MH
Year: 2009
Journal: Nat Immunol
Title: T cell-intrinsic role of Nod2 in promoting type 1 immunity to Toxoplasma gondii.
Volume: 10
Issue: 12
Pages: 1267-74
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Publication
37286542 | J:336655
First Author: Gao J
Year: 2023
Journal: Nat Commun
Title: A probiotic bi-functional peptidoglycan hydrolase sheds NOD2 ligands to regulate gut homeostasis in female mice.
Volume: 14
Issue: 1
Pages: 3338
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Publication
16322770 | J:162740
First Author: Ferwerda G
Year: 2005
Journal: PLoS Pathog
Title: NOD2 and toll-like receptors are nonredundant recognition systems of Mycobacterium tuberculosis.
Volume: 1
Issue: 3
Pages: 279-85
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Publication
21565531 | J:172121
First Author: Kim YG
Year: 2011
Journal: Immunity
Title: The Nod2 sensor promotes intestinal pathogen eradication via the chemokine CCL2-dependent recruitment of inflammatory monocytes.
Volume: 34
Issue: 5
Pages: 769-80
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Publication
12527755 | J:151388
First Author: Girardin SE
Year: 2003
Journal: J Biol Chem
Title: Nod2 is a general sensor of peptidoglycan through muramyl dipeptide (MDP) detection.
Volume: 278
Issue: 11
Pages: 8869-72
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Publication
30559449 | J:268356
First Author: Normand S
Year: 2018
Journal: Nat Commun
Title: Proteasomal degradation of NOD2 by NLRP12 in monocytes promotes bacterial tolerance and colonization by enteropathogens.
Volume: 9
Issue: 1
Pages: 5338
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Publication
23962873 | J:315935
First Author: Amendola A
Year: 2014
Journal: Mucosal Immunol
Title: Nod2 deficiency is associated with an increased mucosal immunoregulatory response to commensal microorganisms.
Volume: 7
Issue: 2
Pages: 391-404
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Publication
32986710 | J:297958
First Author: Pereira NS
Year: 2020
Journal: PLoS Negl Trop Dis
Title: NOD2 receptor is crucial for protecting against the digestive form of Chagas disease.
Volume: 14
Issue: 9
Pages: e0008667
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Publication
28373658 | J:287665
First Author: Rodriguez-Nunez I
Year: 2017
Journal: Sci Rep
Title: Nod2 and Nod2-regulated microbiota protect BALB/c mice from diet-induced obesity and metabolic dysfunction.
Volume: 7
Issue: 1
Pages: 548
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Publication
29234083 | J:286864
First Author: Kale SD
Year: 2017
Journal: Sci Rep
Title: Nod2 is required for the early innate immune clearance of Acinetobacter baumannii from the lungs.
Volume: 7
Issue: 1
Pages: 17429
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Publication
18855982 | J:169873
First Author: Cruickshank SM
Year: 2008
Journal: World J Gastroenterol
Title: Evidence for the involvement of NOD2 in regulating colonic epithelial cell growth and survival.
Volume: 14
Issue: 38
Pages: 5834-41
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Publication
18157816 | J:129266
First Author: Ferwerda G
Year: 2008
Journal: Eur J Immunol
Title: Engagement of NOD2 has a dual effect on proIL-1beta mRNA transcription and secretion of bioactive IL-1beta.
Volume: 38
Issue: 1
Pages: 184-91
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Publication
27325889 | J:236428
First Author: Costa FR
Year: 2016
Journal: J Exp Med
Title: Gut microbiota translocation to the pancreatic lymph nodes triggers NOD2 activation and contributes to T1D onset.
Volume: 213
Issue: 7
Pages: 1223-39
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Publication
19139201 | J:147177
First Author: Deshmukh HS
Year: 2009
Journal: Infect Immun
Title: Critical role of NOD2 in regulating the immune response to Staphylococcus aureus.
Volume: 77
Issue: 4
Pages: 1376-82
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Publication
17277144 | J:143980
First Author: Park JH
Year: 2007
Journal: J Immunol
Title: RICK/RIP2 mediates innate immune responses induced through Nod1 and Nod2 but not TLRs.
Volume: 178
Issue: 4
Pages: 2380-6
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Publication
28576260 | J:273685
 
First Author: Ohlsson C
Year: 2017
Journal: Cell Immunol
Title: Regulation of bone mass by the gut microbiota is dependent on NOD1 and NOD2 signaling.
Volume: 317
Pages: 55-58
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Publication
22750073 | J:188160
First Author: Hiemstra IH
Year: 2012
Journal: Mol Immunol
Title: Nod2 improves barrier function of intestinal epithelial cells via enhancement of TLR responses.
Volume: 52
Issue: 3-4
Pages: 264-72
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Publication
28834747 | J:254240
First Author: Lessard AJ
Year: 2017
Journal: Cell Rep
Title: Triggering of NOD2 Receptor Converts Inflammatory Ly6Chigh into Ly6Clow Monocytes with Patrolling Properties.
Volume: 20
Issue: 8
Pages: 1830-1843
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Publication
37876927 | J:341956
 
First Author: Chauvin C
Year: 2023
Journal: Front Immunol
Title: Loss of NOD2 in macrophages improves colitis and tumorigenesis in a lysozyme-dependent manner.
Volume: 14
Pages: 1252979
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Publication
22547547 | J:186675
First Author: Theivanthiran B
Year: 2012
Journal: Infect Immun
Title: NOD2 signaling contributes to host defense in the lungs against Escherichia coli infection.
Volume: 80
Issue: 7
Pages: 2558-69
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Publication
32101030 | J:294320
First Author: Cavallari JF
Year: 2020
Journal: Am J Physiol Endocrinol Metab
Title: Postbiotics for NOD2 require nonhematopoietic RIPK2 to improve blood glucose and metabolic inflammation in mice.
Volume: 318
Issue: 4
Pages: E579-E585
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Publication
19966812 | J:335668
First Author: Cooney R
Year: 2010
Journal: Nat Med
Title: NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation.
Volume: 16
Issue: 1
Pages: 90-7
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Publication
18768892 | J:139078
First Author: Kim YG
Year: 2008
Journal: J Immunol
Title: Cross-tolerization between Nod1 and Nod2 signaling results in reduced refractoriness to bacterial infection in Nod2-deficient macrophages.
Volume: 181
Issue: 6
Pages: 4340-6
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Publication
21387014 | J:171049
First Author: Petnicki-Ocwieja T
Year: 2011
Journal: PLoS One
Title: Nod2 suppresses Borrelia burgdorferi mediated murine Lyme arthritis and carditis through the induction of tolerance.
Volume: 6
Issue: 2
Pages: e17414
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Publication
28450277 | J:253790
First Author: Saxena A
Year: 2017
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Absence of the NOD2 protein renders epithelia more susceptible to barrier dysfunction due to mitochondrial dysfunction.
Volume: 313
Issue: 1
Pages: G26-G38
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Publication
22607974 | J:188020
First Author: Damgaard RB
Year: 2012
Journal: Mol Cell
Title: The ubiquitin ligase XIAP recruits LUBAC for NOD2 signaling in inflammation and innate immunity.
Volume: 46
Issue: 6
Pages: 746-58
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Publication
24062413 | J:204062
First Author: Jiang W
Year: 2013
Journal: J Exp Med
Title: Recognition of gut microbiota by NOD2 is essential for the homeostasis of intestinal intraepithelial lymphocytes.
Volume: 210
Issue: 11
Pages: 2465-76
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Publication
21296813 | J:181443
First Author: Rosenzweig HL
Year: 2011
Journal: Invest Ophthalmol Vis Sci
Title: NOD2 deficiency results in increased susceptibility to peptidoglycan-induced uveitis in mice.
Volume: 52
Issue: 7
Pages: 4106-12
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Publication
20884650 | J:166945
First Author: Conforti-Andreoni C
Year: 2010
Journal: J Leukoc Biol
Title: Synergism of NOD2 and NLRP3 activators promotes a unique transcriptional profile in murine dendritic cells.
Volume: 88
Issue: 6
Pages: 1207-16
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Publication
24324141 | J:205495
First Author: Yuan H
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Pivotal role of NOD2 in inflammatory processes affecting atherosclerosis and periodontal bone loss.
Volume: 110
Issue: 52
Pages: E5059-68
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Publication
21841315 | J:178245
First Author: Davis KM
Year: 2011
Journal: J Clin Invest
Title: Nod2 sensing of lysozyme-digested peptidoglycan promotes macrophage recruitment and clearance of S. pneumoniae colonization in mice.
Volume: 121
Issue: 9
Pages: 3666-76
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Publication
24591373 | J:209871
First Author: Wu X
Year: 2014
Journal: J Immunol
Title: NOD2 regulates CXCR3-dependent CD8+ T cell accumulation in intestinal tissues with acute injury.
Volume: 192
Issue: 7
Pages: 3409-18
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Publication
24324812 | J:209740
First Author: Zanello G
Year: 2013
Journal: PLoS One
Title: Nod2 activates NF-kB in CD4+ T cells but its expression is dispensable for T cell-induced colitis.
Volume: 8
Issue: 12
Pages: e82623
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Publication
19218085 | J:178054
First Author: Saha S
Year: 2009
Journal: Cell Host Microbe
Title: PGLYRP-2 and Nod2 are both required for peptidoglycan-induced arthritis and local inflammation.
Volume: 5
Issue: 2
Pages: 137-50
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Publication
24107312 | J:321089
 
First Author: Lemire P
Year: 2013
Journal: Microb Pathog
Title: The NOD2 receptor does not play a major role in the pathogenesis of Group B Streptococcus in mice.
Volume: 65
Pages: 41-7
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Publication
21849681 | J:179232
First Author: Kim YG
Year: 2011
Journal: J Immunol
Title: Cutting edge: Crohn's disease-associated Nod2 mutation limits production of proinflammatory cytokines to protect the host from Enterococcus faecalis-induced lethality.
Volume: 187
Issue: 6
Pages: 2849-52
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Publication
19805227 | J:153244
First Author: Petnicki-Ocwieja T
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Nod2 is required for the regulation of commensal microbiota in the intestine.
Volume: 106
Issue: 37
Pages: 15813-8
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Publication
19541630 | J:151511
First Author: Hruz P
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: NOD2 contributes to cutaneous defense against Staphylococcus aureus through alpha-toxin-dependent innate immune activation.
Volume: 106
Issue: 31
Pages: 12873-8
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Publication
32350141 | J:288597
First Author: Prescott D
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: NOD2 modulates immune tolerance via the GM-CSF-dependent generation of CD103+ dendritic cells.
Volume: 117
Issue: 20
Pages: 10946-10957
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Publication
14560001 | J:86264
First Author: Pauleau AL
Year: 2003
Journal: Mol Cell Biol
Title: Role of nod2 in the response of macrophages to toll-like receptor agonists.
Volume: 23
Issue: 21
Pages: 7531-9
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Publication
28647345 | J:252739
First Author: Williams H
Year: 2017
Journal: J Invest Dermatol
Title: Cutaneous Nod2 Expression Regulates the Skin Microbiome and Wound Healing in a Murine Model.
Volume: 137
Issue: 11
Pages: 2427-2436
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Publication
17915219 | J:130116
First Author: Yang Z
Year: 2007
Journal: Gastroenterology
Title: NOD2 transgenic mice exhibit enhanced MDP-mediated down-regulation of TLR2 responses and resistance to colitis induction.
Volume: 133
Issue: 5
Pages: 1510-21
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