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Search results 1 to 100 out of 3528 for Notch1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Liu Z
Year: 2015
Journal: Development
Title: Second-generation Notch1 activity-trap mouse line (N1IP::CreHI) provides a more comprehensive map of cells experiencing Notch1 activity.
Volume: 142
Issue: 6
Pages: 1193-202
Publication
First Author: Liu Z
Year: 2013
Journal: PLoS One
Title: In vivo visualization of Notch1 proteolysis reveals the heterogeneity of Notch1 signaling activity in the mouse cochlea.
Volume: 8
Issue: 5
Pages: e64903
Publication
First Author: Vooijs M
Year: 2007
Journal: Development
Title: Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.
Volume: 134
Issue: 3
Pages: 535-44
Publication
First Author: Liu Z
Year: 2011
Journal: J Clin Invest
Title: Notch1 loss of heterozygosity causes vascular tumors and lethal hemorrhage in mice.
Volume: 121
Issue: 2
Pages: 800-8
Publication  
First Author: Gama-Norton L
Year: 2015
Journal: Nat Commun
Title: Notch signal strength controls cell fate in the haemogenic endothelium.
Volume: 6
Pages: 8510
Publication
First Author: Liu Z
Year: 2009
Journal: Genome Res
Title: Rapid identification of homologous recombinants and determination of gene copy number with reference/query pyrosequencing (RQPS).
Volume: 19
Issue: 11
Pages: 2081-9
Publication
First Author: Liu Z
Year: 2013
Journal: Dev Cell
Title: The extracellular domain of Notch2 increases its cell-surface abundance and ligand responsiveness during kidney development.
Volume: 25
Issue: 6
Pages: 585-98
Publication
First Author: Rodilla V
Year: 2015
Journal: PLoS Biol
Title: Luminal progenitors restrict their lineage potential during mammary gland development.
Volume: 13
Issue: 2
Pages: e1002069
Publication
First Author: Khandekar A
Year: 2016
Journal: Circ Res
Title: Notch-Mediated Epigenetic Regulation of Voltage-Gated Potassium Currents.
Volume: 119
Issue: 12
Pages: 1324-1338
Publication
First Author: Fre S
Year: 2011
Journal: PLoS One
Title: Notch lineages and activity in intestinal stem cells determined by a new set of knock-in mice.
Volume: 6
Issue: 10
Pages: e25785
Publication
First Author: Zhang Y
Year: 2013
Journal: Development
Title: Mastermind-like transcriptional co-activator-mediated Notch signaling is indispensable for maintaining conjunctival epithelial identity.
Volume: 140
Issue: 3
Pages: 594-605
Publication
First Author: Demitrack ES
Year: 2015
Journal: EMBO J
Title: Notch signaling regulates gastric antral LGR5 stem cell function.
Volume: 34
Issue: 20
Pages: 2522-36
Publication
First Author: Diéguez-Hurtado R
Year: 2019
Journal: Nat Commun
Title: Loss of the transcription factor RBPJ induces disease-promoting properties in brain pericytes.
Volume: 10
Issue: 1
Pages: 2817
Publication
First Author: Pellegrinet L
Year: 2011
Journal: Gastroenterology
Title: Dll1- and dll4-mediated notch signaling are required for homeostasis of intestinal stem cells.
Volume: 140
Issue: 4
Pages: 1230-1240.e1-7
Publication
First Author: Morimoto M
Year: 2010
Journal: J Cell Sci
Title: Canonical Notch signaling in the developing lung is required for determination of arterial smooth muscle cells and selection of Clara versus ciliated cell fate.
Volume: 123
Issue: Pt 2
Pages: 213-24
Publication
First Author: King CM
Year: 2011
Journal: PLoS One
Title: Relative number and distribution of murine hypothalamic proopiomelanocortin neurons innervating distinct target sites.
Volume: 6
Issue: 10
Pages: e25864
Publication    
First Author: McKinley KL
Year: 2018
Journal: Elife
Title: Cellular aspect ratio and cell division mechanics underlie the patterning of cell progeny in diverse mammalian epithelia.
Volume: 7
Publication
First Author: Lescroart F
Year: 2018
Journal: Science
Title: Defining the earliest step of cardiovascular lineage segregation by single-cell RNA-seq.
Volume: 359
Issue: 6380
Pages: 1177-1181
Publication
First Author: Hasegawa K
Year: 2012
Journal: Mol Cell Biol
Title: Notch signaling in Sertoli cells regulates cyclical gene expression of Hes1 but is dispensable for mouse spermatogenesis.
Volume: 32
Issue: 1
Pages: 206-15
Publication
First Author: Hilton MJ
Year: 2008
Journal: Nat Med
Title: Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation.
Volume: 14
Issue: 3
Pages: 306-14
Publication      
First Author: The Jackson Laboratory
Year: 2005
Journal: Unpublished
Title: Information obtained from The Jackson Laboratory, Bar Harbor, ME
Gene
Type: gene
Organism: Homo sapiens
GXD Expression
Probe: MGI:6377704
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6378181
Age: embryonic day 10.5
Image: 9B Notch1 Six1-/-
Note: Expression patterns not markedy altered compared with wild type.
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:6377704
Assay Type: RNA in situ
Annotation Date: 2019-11-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760617
Pattern: Not Specified
Stage: TS17
Assay Id: MGI:6378181
Age: embryonic day 10.5
Image: 9B Notch1 WT
Detected: true
Specimen Num: 1
GXD Expression
Probe: MGI:6303822
Assay Type: RNA in situ
Annotation Date: 2019-05-16
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6303840
Age: embryonic day 13.5
Image: S8A E13.5 Cux2neo/neo Notch1
Note: Authors report reduced expression.
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:6303822
Assay Type: RNA in situ
Annotation Date: 2019-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6303840
Age: embryonic day 13.5
Image: S8A E13.5 Control Notch1
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:6303822
Assay Type: RNA in situ
Annotation Date: 2019-05-16
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1760619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6303840
Age: embryonic day 11.5
Image: 7A E11.5 Cux2neo/neo Notch1
Note: Authors report reduced terminal neuronal differentiation.
Specimen Num: 2
GXD Expression  
Probe: MGI:6303822
Assay Type: RNA in situ
Annotation Date: 2019-05-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760619
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6303840
Age: embryonic day 11.5
Image: 7A E11.5 Control Notch1
Detected: true
Specimen Num: 1
Allele
Name: notch 1; targeted mutation 4, Raphael Kopan
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant stock, targeted mutation
Genotype
Symbol: Notch1/Notch1
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Kraman M
Year: 2005
Journal: FASEB J
Title: Functional conservation of Notch1 and Notch2 intracellular domains.
Volume: 19
Issue: 10
Pages: 1311-3
Publication
First Author: Laws AM
Year: 2004
Journal: Eur J Immunol
Title: p53 regulates thymic Notch1 activation.
Volume: 34
Issue: 3
Pages: 726-734
Publication
First Author: Liu J
Year: 2007
Journal: Genesis
Title: Cre-conditional expression of constitutively active Notch1 in transgenic mice.
Volume: 45
Issue: 5
Pages: 259-65
Publication
First Author: Mack JJ
Year: 2017
Journal: Nat Commun
Title: NOTCH1 is a mechanosensor in adult arteries.
Volume: 8
Issue: 1
Pages: 1620
Publication
First Author: Pinnell N
Year: 2015
Journal: Immunity
Title: The PIAS-like Coactivator Zmiz1 Is a Direct and Selective Cofactor of Notch1 in T Cell Development and Leukemia.
Volume: 43
Issue: 5
Pages: 870-83
Publication
First Author: Hasserjian RP
Year: 1996
Journal: Blood
Title: Modulated expression of notch1 during thymocyte development.
Volume: 88
Issue: 3
Pages: 970-6
Publication
First Author: Limbourg FP
Year: 2005
Journal: Circulation
Title: Essential role of endothelial Notch1 in angiogenesis.
Volume: 111
Issue: 14
Pages: 1826-32
Publication
First Author: Asano N
Year: 2008
Journal: J Immunol
Title: Notch1 signaling and regulatory T cell function.
Volume: 180
Issue: 5
Pages: 2796-804
Allele
Name: notch 1; targeted mutation 3, Raphael Kopan
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant stock, targeted mutation
Strain
Attribute String: targeted mutation, mutant stock
Allele
Name: notch 1; targeted mutation 5, Raphael Kopan
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: targeted mutation, mutant stock
Allele
Name: notch 1; targeted mutation 1.1, Spyros Artavanis-Tsakonas
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: coisogenic, mutant strain, targeted mutation
Genotype
Symbol: Notch1/Notch1
Background: involves: 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Notch1/Notch1
Background: C57BL/6-Notch1
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Notch1/Notch1
Background: involves: C57BL/6NTac
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Notch1/Notch1
Background: involves: 129X1/SvJ * C57BL/6J * SJL
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Notch1/Notch1<+>
Background: C57BL/6-Notch1
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Notch1/Notch1<+>
Background: involves: 129S4/SvJaeSor * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Notch1/Notch1<+>
Background: involves: 129S4/SvJaeSor * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Notch1/Notch1<+>
Background: involves: 129X1/SvJ * C57BL/6NTac
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Wakabayashi N
Year: 2010
Journal: Sci Signal
Title: Regulation of notch1 signaling by nrf2: implications for tissue regeneration.
Volume: 3
Issue: 130
Pages: ra52
Publication
First Author: Garg V
Year: 2005
Journal: Nature
Title: Mutations in NOTCH1 cause aortic valve disease.
Volume: 437
Issue: 7056
Pages: 270-4
Publication
First Author: Cortegano I
Year: 2014
Journal: Cell Death Differ
Title: Notch1 regulates progenitor cell proliferation and differentiation during mouse yolk sac hematopoiesis.
Volume: 21
Issue: 7
Pages: 1081-94
Publication
First Author: Zhong R
Year: 2015
Journal: Cancer Res
Title: Notch1 Activation or Loss Promotes HPV-Induced Oral Tumorigenesis.
Volume: 75
Issue: 18
Pages: 3958-3969
Publication
First Author: Lin MH
Year: 2003
Journal: Dev Biol
Title: Long-range, nonautonomous effects of activated Notch1 on tissue homeostasis in the nail.
Volume: 263
Issue: 2
Pages: 343-59
Publication
First Author: MacDonald HR
Year: 2001
Journal: Trends Immunol
Title: Notch1 and T-cell development: insights from conditional knockout mice.
Volume: 22
Issue: 3
Pages: 155-60
Publication
First Author: O'Neil J
Year: 2006
Journal: Blood
Title: Activating Notch1 mutations in mouse models of T-ALL.
Volume: 107
Issue: 2
Pages: 781-5
Publication
First Author: Kang JA
Year: 2014
Journal: Immunology
Title: Notch1 is an important mediator for enhancing of B-cell activation and antibody secretion by Notch ligand.
Volume: 143
Issue: 4
Pages: 550-9
Publication
First Author: Takeshita K
Year: 2007
Journal: Circ Res
Title: Critical role of endothelial Notch1 signaling in postnatal angiogenesis.
Volume: 100
Issue: 1
Pages: 70-8
Publication
First Author: Watanabe Y
Year: 2006
Journal: Development
Title: Activation of Notch1 signaling in cardiogenic mesoderm induces abnormal heart morphogenesis in mouse.
Volume: 133
Issue: 9
Pages: 1625-34
Publication
First Author: Li Y
Year: 2009
Journal: Circulation
Title: Smooth muscle Notch1 mediates neointimal formation after vascular injury.
Volume: 119
Issue: 20
Pages: 2686-92
Publication
First Author: Poulsen LC
Year: 2018
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Endothelial NOTCH1 Signaling Attenuates Inflammation by Reducing Cytokine-Mediated Histone Acetylation at Inflammatory Enhancers.
Volume: 38
Issue: 4
Pages: 854-869
Publication
First Author: Liu J
Year: 2014
Journal: Int J Oncol
Title: Postnatal Notch1 activation induces T‑cell malignancy in conditional and inducible mouse models.
Volume: 45
Issue: 5
Pages: 1997-2004
Publication
First Author: Yashiro-Ohtani Y
Year: 2009
Journal: Genes Dev
Title: Pre-TCR signaling inactivates Notch1 transcription by antagonizing E2A.
Volume: 23
Issue: 14
Pages: 1665-76
Publication
First Author: Swiatek PJ
Year: 1994
Journal: Genes Dev
Title: Notch1 is essential for postimplantation development in mice.
Volume: 8
Issue: 6
Pages: 707-19
Publication
First Author: Huang Z
Year: 2013
Journal: PLoS One
Title: NOTCH1 gain of function in germ cells causes failure of spermatogenesis in male mice.
Volume: 8
Issue: 7
Pages: e71213
Publication
First Author: Conlon RA
Year: 1995
Journal: Development
Title: Notch1 is required for the coordinate segmentation of somites.
Volume: 121
Issue: 5
Pages: 1533-45
Publication
First Author: Liu Z
Year: 2015
Journal: Development
Title: The intracellular domains of Notch1 and Notch2 are functionally equivalent during development and carcinogenesis.
Volume: 142
Issue: 14
Pages: 2452-63
Publication
First Author: Garcia TX
Year: 2013
Journal: Dev Biol
Title: Constitutive activation of NOTCH1 signaling in Sertoli cells causes gonocyte exit from quiescence.
Volume: 377
Issue: 1
Pages: 188-201
Publication
First Author: Chen J
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Notch1 Mutation Leads to Valvular Calcification Through Enhanced Myofibroblast Mechanotransduction.
Volume: 35
Issue: 7
Pages: 1597-605
Publication  
First Author: Zhang K
Year: 2014
Journal: Neurobiol Dis
Title: Notch1 mediates postnatal neurogenesis in hippocampus enhanced by intermittent hypoxia.
Volume: 64
Pages: 66-78
Publication
First Author: Nigam V
Year: 2009
Journal: J Mol Cell Cardiol
Title: Notch1 represses osteogenic pathways in aortic valve cells.
Volume: 47
Issue: 6
Pages: 828-34
Publication
First Author: Monsalve E
Year: 2009
Journal: Eur J Immunol
Title: Notch1 upregulates LPS-induced macrophage activation by increasing NF-kappaB activity.
Volume: 39
Issue: 9
Pages: 2556-70
Publication
First Author: Sawangarun W
Year: 2018
Journal: Exp Cell Res
Title: Loss of Notch1 predisposes oro-esophageal epithelium to tumorigenesis.
Volume: 372
Issue: 2
Pages: 129-140
Publication
First Author: Hu B
Year: 2015
Journal: Am J Pathol
Title: Mesenchymal deficiency of Notch1 attenuates bleomycin-induced pulmonary fibrosis.
Volume: 185
Issue: 11
Pages: 3066-75
Publication
First Author: Nicolas M
Year: 2003
Journal: Nat Genet
Title: Notch1 functions as a tumor suppressor in mouse skin.
Volume: 33
Issue: 3
Pages: 416-21
Publication
First Author: Diévart A
Year: 1999
Journal: Oncogene
Title: Involvement of Notch1 in the development of mouse mammary tumors.
Volume: 18
Issue: 44
Pages: 5973-81
Publication
First Author: Shin HM
Year: 2006
Journal: EMBO J
Title: Notch1 augments NF-kappaB activity by facilitating its nuclear retention.
Volume: 25
Issue: 1
Pages: 129-38
Publication  
First Author: Zanotti S
Year: 2014
Journal: Bone
Title: Notch1 and Notch2 expression in osteoblast precursors regulates femoral microarchitecture.
Volume: 62
Pages: 22-8
Publication  
First Author: Bosse K
Year: 2013
Journal: J Mol Cell Cardiol
Title: Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.
Volume: 60
Pages: 27-35
Publication
First Author: Yugawa T
Year: 2007
Journal: Mol Cell Biol
Title: Regulation of Notch1 gene expression by p53 in epithelial cells.
Volume: 27
Issue: 10
Pages: 3732-42
Publication
First Author: Liu T
Year: 2009
Journal: Am J Pathol
Title: Notch1 signaling in FIZZ1 induction of myofibroblast differentiation.
Volume: 174
Issue: 5
Pages: 1745-55
Publication
First Author: Haller R
Year: 2012
Journal: Cell Death Differ
Title: Notch1 signaling regulates chondrogenic lineage determination through Sox9 activation.
Volume: 19
Issue: 3
Pages: 461-9
Publication
First Author: Genoud S
Year: 2002
Journal: J Cell Biol
Title: Notch1 control of oligodendrocyte differentiation in the spinal cord.
Volume: 158
Issue: 4
Pages: 709-18
Publication
First Author: Saha M
Year: 2017
Journal: Hum Mol Genet
Title: Consequences of MEGF10 deficiency on myoblast function and Notch1 interactions.
Volume: 26
Issue: 15
Pages: 2984-3000
Publication
First Author: Fatima A
Year: 2014
Journal: Dev Dyn
Title: Murine Notch1 is required for lymphatic vascular morphogenesis during development.
Volume: 243
Issue: 7
Pages: 957-64
Publication
First Author: Bansal K
Year: 2011
Journal: J Biol Chem
Title: Intracellular pathogen sensor NOD2 programs macrophages to trigger Notch1 activation.
Volume: 286
Issue: 7
Pages: 5823-35
Publication  
First Author: Guo M
Year: 2012
Journal: Front Biosci (Elite Ed)
Title: P4 down-regulates Jagged2 and Notch1 expression during primordial folliculogenesis.
Volume: 4
Pages: 2631-44
Publication
First Author: Acharya A
Year: 2011
Journal: PLoS One
Title: Inhibitory role of Notch1 in calcific aortic valve disease.
Volume: 6
Issue: 11
Pages: e27743
Publication
First Author: Taichman DB
Year: 2002
Journal: Dev Dyn
Title: Notch1 and Jagged1 expression by the developing pulmonary vasculature.
Volume: 225
Issue: 2
Pages: 166-75
Publication
First Author: Vauclair S
Year: 2005
Journal: Dev Biol
Title: Notch1 is essential for postnatal hair follicle development and homeostasis.
Volume: 284
Issue: 1
Pages: 184-93
Publication  
First Author: Li Z
Year: 2016
Journal: Nat Commun
Title: Epidermal Notch1 recruits RORγ(+) group 3 innate lymphoid cells to orchestrate normal skin repair.
Volume: 7
Pages: 11394
Publication
First Author: Boni A
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Notch1 regulates the fate of cardiac progenitor cells.
Volume: 105
Issue: 40
Pages: 15529-34