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Search results 1 to 100 out of 567 for Notch4

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
GXD Expression    
Probe: MGI:7518840
Assay Type: RT-PCR
Annotation Date: 2023-08-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3667222
Stage: TS22
Assay Id: MGI:7518859
Age: embryonic day 14.5
Image: 5
Specimen Label: Notch4
Detected: true
Specimen Num: 1
Publication
First Author: Miniati D
Year: 2010
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Constitutively active endothelial Notch4 causes lung arteriovenous shunts in mice.
Volume: 298
Issue: 2
Pages: L169-77
Publication  
First Author: Puri RV
Year: 2019
Journal: Dis Model Mech
Title: Notch4 activation aggravates NF-κB-mediated inflammation in HIV-1-associated nephropathy.
Volume: 12
Issue: 12
Publication
First Author: Muley A
Year: 2022
Journal: Angiogenesis
Title: Unique functions for Notch4 in murine embryonic lymphangiogenesis.
Volume: 25
Issue: 2
Pages: 205-224
Publication
First Author: Murphy PA
Year: 2012
Journal: Sci Transl Med
Title: Notch4 normalization reduces blood vessel size in arteriovenous malformations.
Volume: 4
Issue: 117
Pages: 117ra8
Publication
First Author: James AC
Year: 2014
Journal: Biochim Biophys Acta
Title: Notch4 reveals a novel mechanism regulating Notch signal transduction.
Volume: 1843
Issue: 7
Pages: 1272-84
Publication
First Author: Murphy PA
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Endothelial Notch4 signaling induces hallmarks of brain arteriovenous malformations in mice.
Volume: 105
Issue: 31
Pages: 10901-6
Publication  
First Author: Sharma M
Year: 2021
Journal: Data Brief
Title: Transcriptomic data showing differentially expressed genes between Notch3 and Notch4 deleted mice.
Volume: 35
Pages: 106873
Publication
First Author: Carlson TR
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Endothelial expression of constitutively active Notch4 elicits reversible arteriovenous malformations in adult mice.
Volume: 102
Issue: 28
Pages: 9884-9
Publication
First Author: Zheng R
Year: 2018
Journal: J Infect Dis
Title: Notch4 Negatively Regulates the Inflammatory Response to Mycobacterium tuberculosis Infection by Inhibiting TAK1 Activation.
Volume: 218
Issue: 2
Pages: 312-323
Publication
First Author: Sun Y
Year: 2005
Journal: Oncogene
Title: Notch4 intracellular domain binding to Smad3 and inhibition of the TGF-beta signaling.
Volume: 24
Issue: 34
Pages: 5365-74
Publication
First Author: Murphy PA
Year: 2014
Journal: Proc Natl Acad Sci U S A
Title: Constitutively active Notch4 receptor elicits brain arteriovenous malformations through enlargement of capillary-like vessels.
Volume: 111
Issue: 50
Pages: 18007-12
Publication
First Author: Verhein KC
Year: 2015
Journal: Environ Health Perspect
Title: Novel Roles for Notch3 and Notch4 Receptors in Gene Expression and Susceptibility to Ozone-Induced Lung Inflammation in Mice.
Volume: 123
Issue: 8
Pages: 799-805
Publication
First Author: Alabi RO
Year: 2016
Journal: Circ Res
Title: ADAM10-Dependent Signaling Through Notch1 and Notch4 Controls Development of Organ-Specific Vascular Beds.
Volume: 119
Issue: 4
Pages: 519-31
Publication
First Author: Uyttendaele H
Year: 2001
Journal: Proc Natl Acad Sci U S A
Title: Vascular patterning defects associated with expression of activated Notch4 in embryonic endothelium.
Volume: 98
Issue: 10
Pages: 5643-8
Publication
First Author: Uyttendaele H
Year: 1998
Journal: Dev Biol
Title: Notch4 and Wnt-1 proteins function to regulate branching morphogenesis of mammary epithelial cells in an opposing fashion.
Volume: 196
Issue: 2
Pages: 204-17
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689419
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6190919
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Notch4
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6190919
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Notch4
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6190919
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Notch4
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6190919
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Notch4
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190919
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Notch4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190919
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Notch4
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6179187
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:6190919
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Notch4
Detected: false
Specimen Num: 7
Publication
First Author: Murphy PA
Year: 2009
Journal: Lab Invest
Title: Endothelial Notch signaling is upregulated in human brain arteriovenous malformations and a mouse model of the disease.
Volume: 89
Issue: 9
Pages: 971-82
Publication
First Author: Jhappan C
Year: 1992
Journal: Genes Dev
Title: Expression of an activated Notch-related int-3 transgene interferes with cell differentiation and induces neoplastic transformation in mammary and salivary glands.
Volume: 6
Issue: 3
Pages: 345-55
Publication
First Author: Smith GH
Year: 1995
Journal: Cell Growth Differ
Title: Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development.
Volume: 6
Issue: 5
Pages: 563-77
Publication
First Author: Raafat A
Year: 2009
Journal: Oncogene
Title: Rbpj conditional knockout reveals distinct functions of Notch4/Int3 in mammary gland development and tumorigenesis.
Volume: 28
Issue: 2
Pages: 219-30
Publication
First Author: Gallahan D
Year: 1996
Journal: Cancer Res
Title: Expression of a truncated Int3 gene in developing secretory mammary epithelium specifically retards lobular differentiation resulting in tumorigenesis.
Volume: 56
Issue: 8
Pages: 1775-85
Publication
First Author: Takeshita K
Year: 2007
Journal: Circ Res
Title: Critical role of endothelial Notch1 signaling in postnatal angiogenesis.
Volume: 100
Issue: 1
Pages: 70-8
Publication
First Author: Krebs LT
Year: 2000
Journal: Genes Dev
Title: Notch signaling is essential for vascular morphogenesis in mice.
Volume: 14
Issue: 11
Pages: 1343-52
Publication
First Author: Raafat A
Year: 2017
Journal: Sci Rep
Title: The ANK repeats of Notch-4/Int3 activate NF-κB canonical pathway in the absence of Rbpj and causes mammary tumorigenesis.
Volume: 7
Issue: 1
Pages: 13690
Publication
First Author: Uyttendaele H
Year: 1996
Journal: Development
Title: Notch4/int-3, a mammary proto-oncogene, is an endothelial cell-specific mammalian Notch gene.
Volume: 122
Issue: 7
Pages: 2251-9
Publication
First Author: Souilhol C
Year: 2022
Journal: Sci Adv
Title: JAG1-NOTCH4 mechanosensing drives atherosclerosis.
Volume: 8
Issue: 35
Pages: eabo7958
Publication
First Author: Sharma M
Year: 2013
Journal: Am J Physiol Renal Physiol
Title: Inhibition of Notch pathway attenuates the progression of human immunodeficiency virus-associated nephropathy.
Volume: 304
Issue: 8
Pages: F1127-36
Publication
First Author: Liu M
Year: 2017
Journal: Nat Commun
Title: Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Volume: 8
Issue: 1
Pages: 413
Publication
First Author: Hainaud P
Year: 2006
Journal: Cancer Res
Title: The role of the vascular endothelial growth factor-Delta-like 4 ligand/Notch4-ephrin B2 cascade in tumor vessel remodeling and endothelial cell functions.
Volume: 66
Issue: 17
Pages: 8501-10
Publication
First Author: Harb H
Year: 2020
Journal: Nat Immunol
Title: A regulatory T cell Notch4-GDF15 axis licenses tissue inflammation in asthma.
Volume: 21
Issue: 11
Pages: 1359-1370
Publication
First Author: Villa N
Year: 2001
Journal: Mech Dev
Title: Vascular expression of Notch pathway receptors and ligands is restricted to arterial vessels.
Volume: 108
Issue: 1-2
Pages: 161-4
Publication
First Author: Kortschak RD
Year: 2001
Journal: Dev Genes Evol
Title: Evolutionary analysis of vertebrate Notch genes.
Volume: 211
Issue: 7
Pages: 350-4
Publication
First Author: Ortica S
Year: 2014
Journal: FASEB J
Title: The 4 Notch receptors play distinct and antagonistic roles in the proliferation and hepatocytic differentiation of liver progenitors.
Volume: 28
Issue: 2
Pages: 603-14
Publication
First Author: Murtomaki A
Year: 2014
Journal: Development
Title: Notch signaling functions in lymphatic valve formation.
Volume: 141
Issue: 12
Pages: 2446-51
Publication
First Author: Shawber CJ
Year: 2007
Journal: J Clin Invest
Title: Notch alters VEGF responsiveness in human and murine endothelial cells by direct regulation of VEGFR-3 expression.
Volume: 117
Issue: 11
Pages: 3369-82
Publication
First Author: Outtz HH
Year: 2010
Journal: J Immunol
Title: Notch1 deficiency results in decreased inflammation during wound healing and regulates vascular endothelial growth factor receptor-1 and inflammatory cytokine expression in macrophages.
Volume: 185
Issue: 7
Pages: 4363-73
Publication
First Author: Ito T
Year: 2000
Journal: Development
Title: Basic helix-loop-helix transcription factors regulate the neuroendocrine differentiation of fetal mouse pulmonary epithelium.
Volume: 127
Issue: 18
Pages: 3913-21
Publication
First Author: Cormier S
Year: 2004
Journal: Gene Expr Patterns
Title: Developmental expression of the Notch signaling pathway genes during mouse preimplantation development.
Volume: 4
Issue: 6
Pages: 713-7
Publication
First Author: Gazit R
Year: 2004
Journal: Development
Title: Math1 controls cerebellar granule cell differentiation by regulating multiple components of the Notch signaling pathway.
Volume: 131
Issue: 4
Pages: 903-13
Publication
First Author: Helbig C
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Notch controls the magnitude of T helper cell responses by promoting cellular longevity.
Volume: 109
Issue: 23
Pages: 9041-6
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Robbins J
Year: 1992
Journal: J Virol
Title: Mouse mammary tumor gene int-3: a member of the notch gene family transforms mammary epithelial cells.
Volume: 66
Issue: 4
Pages: 2594-9
Publication
First Author: Gallahan D
Year: 1997
Journal: Oncogene
Title: The mouse mammary tumor associated gene INT3 is a unique member of the NOTCH gene family (NOTCH4).
Volume: 14
Issue: 16
Pages: 1883-90
Publication
First Author: Lee JS
Year: 1999
Journal: J Virol
Title: Intracisternal type A particle-mediated activation of the Notch4/int3 gene in a mouse mammary tumor: generation of truncated Notch4/int3 mRNAs by retroviral splicing events.
Volume: 73
Issue: 6
Pages: 5166-71
Publication
First Author: Hubbard EJ
Year: 1997
Journal: Genes Dev
Title: sel-10, a negative regulator of lin-12 activity in Caenorhabditis elegans, encodes a member of the CDC4 family of proteins.
Volume: 11
Issue: 23
Pages: 3182-93
Publication
First Author: Gallahan D
Year: 1987
Journal: J Virol
Title: Mammary tumorigenesis in feral mice: identification of a new int locus in mouse mammary tumor virus (Czech II)-induced mammary tumors.
Volume: 61
Issue: 1
Pages: 66-74
Publication
First Author: Sarkar NH
Year: 1994
Journal: Virology
Title: Insertional mutation of int protooncogenes in the mammary tumors of a new strain of mice derived from the wild in China: normal- and tumor-tissue-specific expression of int-3 transcripts.
Volume: 203
Issue: 1
Pages: 52-62
Publication
First Author: Kordon EC
Year: 1995
Journal: J Virol
Title: A novel non-mouse mammary tumor virus activation of the Int-3 gene in a spontaneous mouse mammary tumor.
Volume: 69
Issue: 12
Pages: 8066-9
Publication  
First Author: Callahan R
Year: 1998
Journal: Biochem Soc Symp
Title: Somatic mutations that contribute to breast cancer.
Volume: 63
Pages: 211-21
Publication
First Author: Bruno RD
Year: 2012
Journal: Oncogene
Title: Notch-induced mammary tumorigenesis does not involve the lobule-limited epithelial progenitor.
Volume: 31
Issue: 1
Pages: 60-7
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3284528
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1697428
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1754928
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3280928
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1778728
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 7
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1757728
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 8
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3599828
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1619828
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 10
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 11
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 12
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 13
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 14
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 15
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1720228
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 16
GXD Expression    
Probe: MGI:1204361
Assay Type: RT-PCR
Annotation Date: 1998-06-01
Strength: Present
Sex: Pooled
Emaps: EMAPS:1750328
Stage: TS28
Assay Id: MGI:1204363
Age: postnatal week 6-8
Image: st96_135
Specimen Label: None
Detected: true
Specimen Num: 17