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Search results 1 to 100 out of 285 for Nox1

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Hits by Strain

Type Details Score
Gene
27035 | NOX1
Type: gene
Organism: human
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Gene
100495329 | nox1
Type: gene
Organism: frog, western clawed
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Gene
119868471 | NOX1
Type: gene
Organism: dog, domestic
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Gene
114243 | Nox1
Type: gene
Organism: rat
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Gene
465752 | NOX1
Type: gene
Organism: chimpanzee
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Gene
521681 | NOX1
Type: gene
Organism: cattle
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Gene
422257 | NOX1
Type: gene
Organism: chicken
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Gene
555604 | nox1
Type: gene
Organism: zebrafish
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Gene
701376 | NOX1
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:2450016 | Nox1
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Domain
IPR029650 | NOX1
Type: Family
Description: ADPH oxidase 1 (NOX1) is a NADPH oxidase that generates superoxide []. It is involved in several cell functions such as proliferation, vascular contraction, host defence, and cytoskeletal remodelling []. It requires small GTPase Rac, Noxa1 and Noxo1 for its activation []. It can be regulated by betaPix through Rac activation [].
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Publication
24792722 | -
First Author: Kaito Y
Year: 2014
Journal: FEBS Lett
Title: Nox1 activation by βPix and the role of Ser-340 phosphorylation.
Volume: 588
Issue: 11
Pages: 1997-2002
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Publication
20580928 | J:163017
First Author: Kahles T
Year: 2010
Journal: Neurobiol Dis
Title: NADPH oxidase Nox1 contributes to ischemic injury in experimental stroke in mice.
Volume: 40
Issue: 1
Pages: 185-92
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Publication
17502491 | J:338041
First Author: Gavazzi G
Year: 2007
Journal: Hypertension
Title: NOX1 deficiency protects from aortic dissection in response to angiotensin II.
Volume: 50
Issue: 1
Pages: 189-96
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Publication
23577160 | J:199934
First Author: Selemidis S
Year: 2013
Journal: PLoS One
Title: Nox1 oxidase suppresses influenza a virus-induced lung inflammation and oxidative stress.
Volume: 8
Issue: 4
Pages: e60792
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Publication
19559686 | J:157217
 
First Author: Jackman KA
Year: 2009
Journal: Brain Res
Title: Importance of NOX1 for angiotensin II-induced cerebrovascular superoxide production and cortical infarct volume following ischemic stroke.
Volume: 1286
Pages: 215-20
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Publication
24501329 | J:229347
First Author: Jiang S
Year: 2014
Journal: Cardiovasc Res
Title: Nox1 NADPH oxidase is necessary for late but not early myocardial ischaemic preconditioning.
Volume: 102
Issue: 1
Pages: 79-87
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Publication
34223172 | J:355583
First Author: Troia A
Year: 2021
Journal: Function (Oxf)
Title: Inhibition of NOX1 Mitigates Blood Pressure Increases in Elastin Insufficiency.
Volume: 2
Issue: 3
Pages: zqab015
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Publication
37820403 | J:344078
 
First Author: Ward J
Year: 2023
Journal: Redox Biol
Title: VEO-IBD NOX1 variant highlights a structural region essential for NOX/DUOX catalytic activity.
Volume: 67
Pages: 102905
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Publication
16230485 | J:127882
First Author: Dikalova A
Year: 2005
Journal: Circulation
Title: Nox1 overexpression potentiates angiotensin II-induced hypertension and vascular smooth muscle hypertrophy in transgenic mice.
Volume: 112
Issue: 17
Pages: 2668-76
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Publication
25151121 | J:220103
 
First Author: Zanetti F
Year: 2014
Journal: Free Radic Biol Med
Title: Nicotine mediates oxidative stress and apoptosis through cross talk between NOX1 and Bcl-2 in lung epithelial cells.
Volume: 76
Pages: 173-84
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Publication
25228390 | J:251441
First Author: Streeter J
Year: 2014
Journal: Circ Res
Title: Phosphorylation of Nox1 regulates association with NoxA1 activation domain.
Volume: 115
Issue: 11
Pages: 911-8
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Publication
33513310 | J:325591
First Author: Qin W
Year: 2021
Journal: Am J Respir Cell Mol Biol
Title: NOX1 Promotes Mesothelial-Mesenchymal Transition through Modulation of Reactive Oxygen Species-mediated Signaling.
Volume: 64
Issue: 4
Pages: 492-503
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Publication
26222337 | J:238611
First Author: Lan T
Year: 2015
Journal: PLoS One
Title: Deficiency of NOX1 or NOX4 Prevents Liver Inflammation and Fibrosis in Mice through Inhibition of Hepatic Stellate Cell Activation.
Volume: 10
Issue: 7
Pages: e0129743
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Publication
26876598 | J:315994
First Author: Kato M
Year: 2016
Journal: Exp Anim
Title: The ROS-generating oxidase Nox1 is required for epithelial restitution following colitis.
Volume: 65
Issue: 3
Pages: 197-205
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Publication
16246966 | J:116837
First Author: Matsuno K
Year: 2005
Journal: Circulation
Title: Nox1 is involved in angiotensin II-mediated hypertension: a study in Nox1-deficient mice.
Volume: 112
Issue: 17
Pages: 2677-85
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Publication
24374371 | J:211847
 
First Author: Esworthy RS
Year: 2014
Journal: Free Radic Biol Med
Title: Nox1 causes ileocolitis in mice deficient in glutathione peroxidase-1 and -2.
Volume: 68
Pages: 315-25
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Publication
24551274 | J:333592
First Author: Carnesecchi S
Year: 2014
Journal: Int J Clin Exp Pathol
Title: NOX1 is responsible for cell death through STAT3 activation in hyperoxia and is associated with the pathogenesis of acute respiratory distress syndrome.
Volume: 7
Issue: 2
Pages: 537-51
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Publication
23241962 | J:194294
First Author: Leoni G
Year: 2013
Journal: J Clin Invest
Title: Annexin A1, formyl peptide receptor, and NOX1 orchestrate epithelial repair.
Volume: 123
Issue: 1
Pages: 443-54
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Publication
23216904 | J:214577
First Author: Kodama R
Year: 2013
Journal: Genes Cells
Title: ROS-generating oxidases Nox1 and Nox4 contribute to oncogenic Ras-induced premature senescence.
Volume: 18
Issue: 1
Pages: 32-41
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Publication
22403796 | J:190175
First Author: Yasuda M
Year: 2012
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Potential role of the NADPH oxidase NOX1 in the pathogenesis of 5-fluorouracil-induced intestinal mucositis in mice.
Volume: 302
Issue: 10
Pages: G1133-42
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Publication
20639222 | J:164598
First Author: Dikalova AE
Year: 2010
Journal: Am J Physiol Heart Circ Physiol
Title: Upregulation of Nox1 in vascular smooth muscle leads to impaired endothelium-dependent relaxation via eNOS uncoupling.
Volume: 299
Issue: 3
Pages: H673-9
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Publication
16724959 | J:341404
First Author: Arakawa N
Year: 2006
Journal: Biochem J
Title: Novel transcripts of Nox1 are regulated by alternative promoters and expressed under phenotypic modulation of vascular smooth muscle cells.
Volume: 398
Issue: 2
Pages: 303-10
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Publication
25701431 | J:255372
 
First Author: Zhu K
Year: 2015
Journal: Free Radic Biol Med
Title: NADPH oxidase NOX1 is involved in activation of protein kinase C and premature senescence in early stage diabetic kidney.
Volume: 83
Pages: 21-30
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Protein
Q8CIZ9
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
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Protein
A0A0R4J1X7
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
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Protein
E0CYB0
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false
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Publication
17275676 | -
First Author: BelAiba RS
Year: 2007
Journal: Free Radic Biol Med
Title: NOX5 variants are functionally active in endothelial cells.
Volume: 42
Issue: 4
Pages: 446-59
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Publication
23322165 | -
First Author: Debbabi M
Year: 2013
Journal: FASEB J
Title: NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation.
Volume: 27
Issue: 4
Pages: 1733-48
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Publication
12473664 | J:81679
First Author: Bánfi B
Year: 2003
Journal: J Biol Chem
Title: Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
Volume: 278
Issue: 6
Pages: 3510-3
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Publication
16386251 | J:105425
First Author: Gavazzi G
Year: 2006
Journal: FEBS Lett
Title: Decreased blood pressure in NOX1-deficient mice.
Volume: 580
Issue: 2
Pages: 497-504
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Publication
24086556 | J:206017
First Author: Hernandes MS
Year: 2013
Journal: PLoS One
Title: Microglial cells are involved in the susceptibility of NADPH oxidase knockout mice to 6-hydroxy-dopamine-induced neurodegeneration.
Volume: 8
Issue: 9
Pages: e75532
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Publication
19150879 | J:159782
First Author: Lee MY
Year: 2009
Journal: Arterioscler Thromb Vasc Biol
Title: Mechanisms of vascular smooth muscle NADPH oxidase 1 (Nox1) contribution to injury-induced neointimal formation.
Volume: 29
Issue: 4
Pages: 480-7
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Publication
28028364 | J:271830
First Author: Chu FF
Year: 2016
Journal: World J Gastroenterol
Title: NADPH oxidase-1 deficiency offers little protection in Salmonella typhimurium-induced typhlitis in mice.
Volume: 22
Issue: 46
Pages: 10158-10165
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Publication
37635877 | J:340049
 
First Author: Valdivia A
Year: 2023
Journal: Front Cell Dev Biol
Title: Nox1-based NADPH oxidase regulates the Par protein complex activity to control cell polarization.
Volume: 11
Pages: 1231489
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Publication
20351171 | J:162587
First Author: Coant N
Year: 2010
Journal: Mol Cell Biol
Title: NADPH oxidase 1 modulates WNT and NOTCH1 signaling to control the fate of proliferative progenitor cells in the colon.
Volume: 30
Issue: 11
Pages: 2636-50
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Publication
31812669 | J:283509
 
First Author: França KC
Year: 2020
Journal: Arch Biochem Biophys
Title: Quiescin/sulfhydryl oxidase 1b (QSOX1b) induces migration and proliferation of vascular smooth muscle cells by distinct redox pathways.
Volume: 679
Pages: 108220
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Publication
23087362 | J:208311
First Author: Csányi G
Year: 2012
Journal: Arterioscler Thromb Vasc Biol
Title: Thrombospondin-1 regulates blood flow via CD47 receptor-mediated activation of NADPH oxidase 1.
Volume: 32
Issue: 12
Pages: 2966-73
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Publication
33301718 | J:321674
First Author: Miller BM
Year: 2020
Journal: Cell Host Microbe
Title: Anaerobic Respiration of NOX1-Derived Hydrogen Peroxide Licenses Bacterial Growth at the Colonic Surface.
Volume: 28
Issue: 6
Pages: 789-797.e5
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Publication
27489105 | J:237252
First Author: Xu Q
Year: 2016
Journal: J Biol Chem
Title: NADPH Oxidases Are Essential for Macrophage Differentiation.
Volume: 291
Issue: 38
Pages: 20030-41
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Publication
18397177 | J:136643
First Author: Li Q
Year: 2008
Journal: Biochem J
Title: Endosomal NADPH oxidase regulates c-Src activation following hypoxia/reoxygenation injury.
Volume: 411
Issue: 3
Pages: 531-41
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Publication
26988594 | J:246689
First Author: Delaney MK
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Differential Roles of the NADPH-Oxidase 1 and 2 in Platelet Activation and Thrombosis.
Volume: 36
Issue: 5
Pages: 846-54
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Publication
19661248 | J:167959
First Author: Carnesecchi S
Year: 2009
Journal: Am J Respir Crit Care Med
Title: NADPH oxidase-1 plays a crucial role in hyperoxia-induced acute lung injury in mice.
Volume: 180
Issue: 10
Pages: 972-81
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Publication
25066694 | J:355601
 
First Author: Siu KL
Year: 2015
Journal: J Mol Cell Cardiol
Title: Netrin-1 abrogates ischemia/reperfusion-induced cardiac mitochondrial dysfunction via nitric oxide-dependent attenuation of NOX4 activation and recoupling of NOS.
Volume: 78
Pages: 174-85
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Publication
29042481 | J:259049
 
First Author: Meijles DN
Year: 2017
Journal: Sci Signal
Title: The matricellular protein TSP1 promotes human and mouse endothelial cell senescence through CD47 and Nox1.
Volume: 10
Issue: 501
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Publication
19679834 | J:169970
First Author: Schröder K
Year: 2009
Journal: Circ Res
Title: NADPH oxidase Nox2 is required for hypoxia-induced mobilization of endothelial progenitor cells.
Volume: 105
Issue: 6
Pages: 537-44
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Publication
21326871 | J:170891
First Author: Garrido-Urbani S
Year: 2011
Journal: PLoS One
Title: Targeting vascular NADPH oxidase 1 blocks tumor angiogenesis through a PPARα mediated mechanism.
Volume: 6
Issue: 2
Pages: e14665
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Publication
27399878 | J:240128
First Author: Leisegang MS
Year: 2016
Journal: Endocrinology
Title: The NADPH Oxidase Nox2 Mediates Vitamin D-Induced Vascular Regeneration in Male Mice.
Volume: 157
Issue: 10
Pages: 4032-4040
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Publication
36709665 | J:336269
 
First Author: Mason H
Year: 2023
Journal: Redox Biol
Title: Development of an improved and specific inhibitor of NADPH oxidase 2 to treat traumatic brain injury.
Volume: 60
Pages: 102611
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Publication
22456182 | J:212519
First Author: Schröder K
Year: 2012
Journal: Circ Res
Title: Nox4 is a protective reactive oxygen species generating vascular NADPH oxidase.
Volume: 110
Issue: 9
Pages: 1217-25
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Publication
34784249 | J:337880
First Author: Gu F
Year: 2021
Journal: Sci Signal
Title: Dual NADPH oxidases DUOX1 and DUOX2 synthesize NAADP and are necessary for Ca(2+) signaling during T cell activation.
Volume: 14
Issue: 709
Pages: eabe3800
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Publication
17853944 | J:127563
First Author: Marden JJ
Year: 2007
Journal: J Clin Invest
Title: Redox modifier genes in amyotrophic lateral sclerosis in mice.
Volume: 117
Issue: 10
Pages: 2913-9
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Publication
31919083 | J:321391
First Author: Prieto-Bermejo R
Year: 2021
Journal: Haematologica
Title: Cyba-deficient mice display an increase in hematopoietic stem cells and an overproduction of immunoglobulins.
Volume: 106
Issue: 1
Pages: 142-153
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Publication
24051369 | J:224963
 
First Author: Braunersreuther V
Year: 2013
Journal: J Mol Cell Cardiol
Title: Role of NADPH oxidase isoforms NOX1, NOX2 and NOX4 in myocardial ischemia/reperfusion injury.
Volume: 64
Pages: 99-107
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Publication
33826887 | J:317399
First Author: van der Post S
Year: 2021
Journal: Cell Rep
Title: NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation.
Volume: 35
Issue: 1
Pages: 108949
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Publication
23836548 | J:199445
First Author: Lelli A
Year: 2013
Journal: Glia
Title: The NADPH oxidase Nox2 regulates VEGFR1/CSF-1R-mediated microglial chemotaxis and promotes early postnatal infiltration of phagocytes in the subventricular zone of the mouse cerebral cortex.
Volume: 61
Issue: 9
Pages: 1542-55
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Publication
23564668 | J:211396
First Author: Gray SP
Year: 2013
Journal: Circulation
Title: NADPH oxidase 1 plays a key role in diabetes mellitus-accelerated atherosclerosis.
Volume: 127
Issue: 18
Pages: 1888-902
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Publication
33267663 | J:306975
First Author: Vara D
Year: 2021
Journal: Arterioscler Thromb Vasc Biol
Title: NADPH Oxidases Are Required for Full Platelet Activation In Vitro and Thrombosis In Vivo but Dispensable for Plasma Coagulation and Hemostasis.
Volume: 41
Issue: 2
Pages: 683-697
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Publication
20877715 | J:166948
 
First Author: Kleinschnitz C
Year: 2010
Journal: PLoS Biol
Title: Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration.
Volume: 8
Issue: 9
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Publication
25116588 | J:216185
First Author: Trocme C
Year: 2015
Journal: J Pathol
Title: Macrophage-specific NOX2 contributes to the development of lung emphysema through modulation of SIRT1/MMP-9 pathways.
Volume: 235
Issue: 1
Pages: 65-78
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Publication
19005069 | J:142401
First Author: Chéret C
Year: 2008
Journal: J Neurosci
Title: Neurotoxic activation of microglia is promoted by a nox1-dependent NADPH oxidase.
Volume: 28
Issue: 46
Pages: 12039-51
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Publication
26715682 | J:247231
First Author: Gray SP
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Reactive Oxygen Species Can Provide Atheroprotection via NOX4-Dependent Inhibition of Inflammation and Vascular Remodeling.
Volume: 36
Issue: 2
Pages: 295-307
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Publication
28165467 | J:319406
First Author: Cha JJ
Year: 2017
Journal: Lab Invest
Title: APX-115, a first-in-class pan-NADPH oxidase (Nox) inhibitor, protects db/db mice from renal injury.
Volume: 97
Issue: 4
Pages: 419-431
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Publication
33127391 | J:309652
First Author: Burgueño JF
Year: 2021
Journal: Gastroenterology
Title: Epithelial TLR4 Signaling Activates DUOX2 to Induce Microbiota-Driven Tumorigenesis.
Volume: 160
Issue: 3
Pages: 797-808.e6
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Publication
30445007 | J:293707
First Author: Liang S
Year: 2019
Journal: Gastroenterology
Title: NADPH Oxidase 1 in Liver Macrophages Promotes Inflammation and Tumor Development in Mice.
Volume: 156
Issue: 4
Pages: 1156-1172.e6
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Publication
33310189 | J:305512
 
First Author: Zhang X
Year: 2021
Journal: Biochem Biophys Res Commun
Title: NOX1/NADPH oxidase affects the development of autism-like behaviors in a maternal immune activation model.
Volume: 534
Pages: 59-66
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Publication
22159121 | J:322096
First Author: Ibi M
Year: 2011
Journal: J Neurosci
Title: Involvement of NOX1/NADPH oxidase in morphine-induced analgesia and tolerance.
Volume: 31
Issue: 49
Pages: 18094-103
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Publication
22982050 | J:190124
First Author: Matsuno K
Year: 2012
Journal: Free Radic Biol Med
Title: NOX1/NADPH oxidase is involved in endotoxin-induced cardiomyocyte apoptosis.
Volume: 53
Issue: 9
Pages: 1718-28
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Publication
28684629 | J:267232
First Author: Thompson JA
Year: 2017
Journal: Circ Res
Title: Genetic Deletion of NADPH Oxidase 1 Rescues Microvascular Function in Mice With Metabolic Disease.
Volume: 121
Issue: 5
Pages: 502-511
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Publication
29867954 | J:310360
 
First Author: Moll F
Year: 2018
Journal: Front Immunol
Title: NoxO1 Controls Proliferation of Colon Epithelial Cells.
Volume: 9
Pages: 973
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Publication
24053718 | J:318241
First Author: Wilkinson-Berka JL
Year: 2014
Journal: Antioxid Redox Signal
Title: NADPH oxidase, NOX1, mediates vascular injury in ischemic retinopathy.
Volume: 20
Issue: 17
Pages: 2726-40
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Publication
23639811 | J:202785
First Author: Spencer NY
Year: 2013
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatocytes produce TNF-α following hypoxia-reoxygenation and liver ischemia-reperfusion in a NADPH oxidase- and c-Src-dependent manner.
Volume: 305
Issue: 1
Pages: G84-94
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Publication
31308397 | J:286710
First Author: Charbonneau ME
Year: 2019
Journal: Sci Rep
Title: Perturbation of ubiquitin homeostasis promotes macrophage oxidative defenses.
Volume: 9
Issue: 1
Pages: 10245
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Publication
22933115 | J:208488
First Author: Li N
Year: 2012
Journal: Diabetes
Title: NADPH oxidase NOX2 defines a new antagonistic role for reactive oxygen species and cAMP/PKA in the regulation of insulin secretion.
Volume: 61
Issue: 11
Pages: 2842-50
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Publication
29471108 | J:319927
 
First Author: Jiménez-Altayó F
Year: 2018
Journal: Free Radic Biol Med
Title: Redox stress in Marfan syndrome: Dissecting the role of the NADPH oxidase NOX4 in aortic aneurysm.
Volume: 118
Pages: 44-58
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Publication
24233492 | J:224121
First Author: Iwata K
Year: 2014
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency of NOX1/nicotinamide adenine dinucleotide phosphate, reduced form oxidase leads to pulmonary vascular remodeling.
Volume: 34
Issue: 1
Pages: 110-9
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Publication
32533834 | J:329640
First Author: Ouerd S
Year: 2021
Journal: Cardiovasc Res
Title: Endothelium-restricted endothelin-1 overexpression in type 1 diabetes worsens atherosclerosis and immune cell infiltration via NOX1.
Volume: 117
Issue: 4
Pages: 1144-1153
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Publication
31871440 | J:313650
 
First Author: Burgueño JF
Year: 2019
Journal: Front Physiol
Title: Intestinal Epithelial Cells Respond to Chronic Inflammation and Dysbiosis by Synthesizing H2O2.
Volume: 10
Pages: 1484
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Publication
20224597 | J:186364
First Author: Ben Mkaddem S
Year: 2010
Journal: Cell Death Differ
Title: Heat shock protein gp96 and NAD(P)H oxidase 4 play key roles in Toll-like receptor 4-activated apoptosis during renal ischemia/reperfusion injury.
Volume: 17
Issue: 9
Pages: 1474-85
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Publication
25317947 | J:218028
   
First Author: Yang Z
Year: 2014
Journal: Elife
Title: Female resistance to pneumonia identifies lung macrophage nitric oxide synthase-3 as a therapeutic target.
Volume: 3
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Publication
26689330 | J:231185
 
First Author: Hsieh LT
Year: 2016
Journal: Matrix Biol
Title: Bimodal role of NADPH oxidases in the regulation of biglycan-triggered IL-1β synthesis.
Volume: 49
Pages: 61-81
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Publication
33053375 | J:325907
First Author: Chanin RB
Year: 2020
Journal: Cell Host Microbe
Title: Epithelial-Derived Reactive Oxygen Species Enable AppBCX-Mediated Aerobic Respiration of Escherichia coli during Intestinal Inflammation.
Volume: 28
Issue: 6
Pages: 780-788.e5
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First Author: Siu KL
Year: 2017
Journal: Redox Biol
Title: NOX isoforms in the development of abdominal aortic aneurysm.
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Journal: Lab Invest
Title: Accelerated atherosclerosis development in C57Bl6 mice by overexpressing AAV-mediated PCSK9 and partial carotid ligation.
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Title: Anticancer Mechanisms in Two Murine Bone Marrow-Derived Dendritic Cell Subsets Activated with TLR4 Agonists.
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First Author: Ohata H
Year: 2019
Journal: Cell Rep
Title: NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression.
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Pages: 1282-1295.e8
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First Author: Morimoto H
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Journal: Life Sci Alliance
Title: ROS amplification drives mouse spermatogonial stem cell self-renewal.
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First Author: Dammanahalli JK
Year: 2011
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Title: Genetic interleukin-10 deficiency causes vascular remodeling via the upregulation of Nox1.
Volume: 29
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First Author: Yeligar SM
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Title: Ethanol induces oxidative stress in alveolar macrophages via upregulation of NADPH oxidases.
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Title: Reactive oxygen species derived from NOX1/NADPH oxidase enhance inflammatory pain.
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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