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Search results 1 to 100 out of 123 for Nox3

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
50508 | NOX3
Type: gene
Organism: human
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Gene
526999 | NOX3
Type: gene
Organism: cattle
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Gene
428609 | NOX3
Type: gene
Organism: chicken
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Gene
701576 | NOX3
Type: gene
Organism: macaque, rhesus
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Gene
292279 | Nox3
Type: gene
Organism: rat
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Gene
484046 | NOX3
Type: gene
Organism: dog, domestic
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Gene
472169 | NOX3
Type: gene
Organism: chimpanzee
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Protein Domain
IPR029653 | NOX3
Type: Family
Description: ADPH oxidase 3 (NOX3) is a NADPH oxidase that generates superoxide []. NOX3 may play a role in generating reactiveoxygen species (ROS) that can react with target molecules within the cochlea, leading to irreversible damage and causing hearing loss [].
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Protein Coding Gene
MGI:2681162 | Nox3
Type: protein_coding_gene
Organism: mouse, laboratory
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GXD Expression
GXD Expression
   
Probe: MGI:3828271
Assay Type: RT-PCR
Annotation Date: 2009-01-22
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619427
Stage: TS27
Assay Id: MGI:3828275
Age: postnatal day 3
Image: 1
Specimen Label: Nox3 IE
Detected: true
Specimen Num: 2
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Publication
21161235 | J:169054
First Author: Flaherty JP
Year: 2011
Journal: Mamm Genome
Title: Molecular characterization of an allelic series of mutations in the mouse Nox3 gene.
Volume: 22
Issue: 3-4
Pages: 156-69
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Publication
25947060 | J:222961
First Author: Morimoto H
Year: 2015
Journal: Biol Reprod
Title: ROS-Generating Oxidase Nox3 Regulates the Self-Renewal of Mouse Spermatogonial Stem Cells.
Volume: 92
Issue: 6
Pages: 147
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Publication
25880434 | J:224696
First Author: Lavinsky J
Year: 2015
Journal: PLoS Genet
Title: Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss.
Volume: 11
Issue: 4
Pages: e1005094
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Publication
22562580 | -
First Author: Rybak LP
Year: 2012
Journal: Cell Mol Life Sci
Title: siRNA-mediated knock-down of NOX3: therapy for hearing loss?
Volume: 69
Issue: 14
Pages: 2429-34
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Publication
- | J:108827
     
First Author: McCarty C
Year: 2006
Journal: MGI Direct Data Submission
Title: Sequence analysis of nmf250 identifies a splicing mutation near exon 10 of Nox3
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Publication
17237347 | -
First Author: Bedard K
Year: 2007
Journal: Physiol Rev
Title: The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Volume: 87
Issue: 1
Pages: 245-313
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Protein
Q672J9
Organism: Mus musculus/domesticus
Length: 568  
Fragment?: false
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Publication
33849947 | J:306032
First Author: Mohri H
Year: 2021
Journal: J Neurosci
Title: Nox3-Derived Superoxide in Cochleae Induces Sensorineural Hearing Loss.
Volume: 41
Issue: 21
Pages: 4716-4731
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Publication
15501603 | J:109414
First Author: Fuller PM
Year: 2004
Journal: Neuroscience
Title: Evidence for macular gravity receptor modulation of hypothalamic, limbic and autonomic nuclei.
Volume: 129
Issue: 2
Pages: 461-71
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Publication
15326186 | J:94490
First Author: Bánfi B
Year: 2004
Journal: J Biol Chem
Title: NOX3, a superoxide-generating NADPH oxidase of the inner ear.
Volume: 279
Issue: 44
Pages: 46065-72
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Publication
30853403 | J:275465
First Author: Mazzonetto PC
Year: 2019
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Mutation in NADPH oxidase 3 (NOX3) impairs SHH signaling and increases cerebellar neural stem/progenitor cell proliferation.
Volume: 1865
Issue: 6
Pages: 1502-1515
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Publication
17140397 | J:121409
First Author: Nakano Y
Year: 2007
Journal: Biochem J
Title: Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3.
Volume: 403
Issue: 1
Pages: 97-108
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Publication
20647313 | J:166388
First Author: Gao D
Year: 2010
Journal: J Biol Chem
Title: The effects of palmitate on hepatic insulin resistance are mediated by NADPH Oxidase 3-derived reactive oxygen species through JNK and p38MAPK pathways.
Volume: 285
Issue: 39
Pages: 29965-73
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Protein Coding Gene
MGP_CAROLIEiJ_G0021020 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0023101 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0023072 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0023038 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0023074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0022833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2681162 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0023520 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0022352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0022801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0022936 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0022910 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0023005 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0022931 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0023537 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0022097 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0022403 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023338 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0021925 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12711080 | J:83379
First Author: Harrod CG
Year: 2003
Journal: Brain Res
Title: The vestibulo ocular reflex (VOR) in otoconia deficient head tilt (het) mutant mice versus wild type C57BL/6 mice.
Volume: 972
Issue: 1-2
Pages: 75-83
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Publication
17023128 | J:115261
First Author: Hoffman LF
Year: 2006
Journal: Hear Res
Title: Afferent synapses are present in utricular hair cells from otoconia-deficient mice.
Volume: 222
Issue: 1-2
Pages: 35-42
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Publication
15059776 | J:95596
First Author: Xue B
Year: 2004
Journal: Am J Physiol Heart Circ Physiol
Title: Diminished baroreflex control of heart rate responses in otoconia-deficient C57BL/6JEi head tilt mice.
Volume: 287
Issue: 2
Pages: H741-7
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Publication
10491954 | J:59485
First Author: Jones SM
Year: 1999
Journal: Hear Res
Title: Vestibular responses to linear acceleration are absent in otoconia-deficient C57BL/6JEi-het mice.
Volume: 135
Issue: 1-2
Pages: 56-60
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Publication
12434016 | J:88596
First Author: Fuller PM
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: Neurovestibular modulation of circadian and homeostatic regulation: vestibulohypothalamic connection?
Volume: 99
Issue: 24
Pages: 15723-8
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Publication
- | J:76316
     
First Author: Monroe RJ
Year: 2002
Journal: MGI Direct Data Submission
Title: A new allele at the head-tilt (het) locus
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Publication
- | J:169743
     
First Author: Bergstrom D
Year: 2011
Journal: Personal Communication
Title: Nox3het-5J
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729225
Stage: TS25
Assay Id: MGI:5896777
Age: embryonic day 17.5
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729525
Stage: TS25
Assay Id: MGI:5896777
Age: embryonic day 17.5
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728625
Stage: TS25
Assay Id: MGI:5896777
Age: embryonic day 17.5
Image: 7
Specimen Label: Ampulla
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283225
Stage: TS25
Assay Id: MGI:5896777
Age: embryonic day 17.5
Image: 7
Specimen Label: Canal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524725
Stage: TS25
Assay Id: MGI:5896777
Age: embryonic day 17.5
Image: 7
Specimen Label: Cochlea
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729227
Stage: TS27
Assay Id: MGI:5896778
Age: postnatal day 0
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729527
Stage: TS27
Assay Id: MGI:5896778
Age: postnatal day 0
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283127
Stage: TS27
Assay Id: MGI:5896778
Age: postnatal day 0
Image: 7
Specimen Label: Ampulla
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283227
Stage: TS27
Assay Id: MGI:5896778
Age: postnatal day 0
Image: 7
Specimen Label: Canal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524727
Stage: TS27
Assay Id: MGI:5896778
Age: postnatal day 0
Image: 7
Specimen Label: Cochlea
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729228
Stage: TS28
Assay Id: MGI:5896779
Age: postnatal day 7
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729528
Stage: TS28
Assay Id: MGI:5896779
Age: postnatal day 7
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283128
Stage: TS28
Assay Id: MGI:5896779
Age: postnatal day 7
Image: 7
Specimen Label: Ampulla
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283228
Stage: TS28
Assay Id: MGI:5896779
Age: postnatal day 7
Image: 7
Specimen Label: Canal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524728
Stage: TS28
Assay Id: MGI:5896779
Age: postnatal day 7
Image: 7
Specimen Label: Cochlea
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729228
Stage: TS28
Assay Id: MGI:5896780
Age: postnatal month 1.5
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729528
Stage: TS28
Assay Id: MGI:5896780
Age: postnatal month 1.5
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283128
Stage: TS28
Assay Id: MGI:5896780
Age: postnatal month 1.5
Image: 7
Specimen Label: Ampulla
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283228
Stage: TS28
Assay Id: MGI:5896780
Age: postnatal month 1.5
Image: 7
Specimen Label: Canal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524728
Stage: TS28
Assay Id: MGI:5896780
Age: postnatal month 1.5
Image: 7
Specimen Label: Cochlea
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729228
Stage: TS28
Assay Id: MGI:5896781
Age: postnatal month 18
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729528
Stage: TS28
Assay Id: MGI:5896781
Age: postnatal month 18
Image: 7
Specimen Label: U + S
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283128
Stage: TS28
Assay Id: MGI:5896781
Age: postnatal month 18
Image: 7
Specimen Label: Ampulla
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283228
Stage: TS28
Assay Id: MGI:5896781
Age: postnatal month 18
Image: 7
Specimen Label: Canal
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5896561
Assay Type: RT-PCR
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3524728
Stage: TS28
Assay Id: MGI:5896781
Age: postnatal month 18
Image: 7
Specimen Label: Cochlea
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3690759
Assay Type: RT-PCR
Annotation Date: 2006-12-14
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3783327
Stage: TS27
Assay Id: MGI:3690783
Age: postnatal day 2
Specimen Label: neonatal CM
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
Probe: MGI:5896773
Assay Type: Immunohistochemistry
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3283225
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5896782
Age: embryonic day 17.5
Image: 7G
Note: Expression is in epithelial cells.
Specimen Label: 7G
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:5896773
Assay Type: Immunohistochemistry
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729225
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5896782
Age: embryonic day 17.5
Note: Expression is at the apical membrane of hair cells.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:5896773
Assay Type: Immunohistochemistry
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1728625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:5896782
Age: embryonic day 17.5
Note: Expression is at the apical membrane of hair cells in the crista.
Specimen Label: not shown
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
Probe: MGI:5896773
Assay Type: Immunohistochemistry
Annotation Date: 2017-05-07
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1729525
Pattern: Not Specified
Stage: TS25
Assay Id: MGI:5896782
Age: embryonic day 17.5
Image: 7F
Note: Expression is at the apical membrane of hair cells.
Specimen Label: 7F
Detected: true
Specimen Num: 1
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Publication
15014044 | J:89010
First Author: Paffenholz R
Year: 2004
Journal: Genes Dev
Title: Vestibular defects in head-tilt mice result from mutations in Nox3, encoding an NADPH oxidase.
Volume: 18
Issue: 5
Pages: 486-91
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Publication
18355969 | J:136073
First Author: Zhao X
Year: 2008
Journal: Neuroscience
Title: Otoconin-90 deletion leads to imbalance but normal hearing: a comparison with other otoconia mutants.
Volume: 153
Issue: 1
Pages: 289-99
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Publication
- | J:56803
     
First Author: Cook S
Year: 1999
Journal: MGI Direct Data Submission
Title: The Jackson Laboratory Mouse Mutant Resource 1999 Mutation Reports
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Publication
- | J:82238
     
First Author: JAX Neuroscience Mutagenesis Facility
Year: 2003
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from JAX NMF ENU Mutagenesis Program
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Publication
9755211 | J:50247
First Author: Bergstrom RA
Year: 1998
Journal: Genetics
Title: Deletion mapping of the head tilt (het) gene in mice: a vestibular mutation causing specific absence of otoliths.
Volume: 150
Issue: 2
Pages: 815-22
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Publication
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