|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 82 out of 82 for Noxa1

0.026s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: NADPH oxidase activator 1 (NOXA1), also known as p51-nox or p67phox-like factor, functions as an activator of NOX1 and NOX2, members of the Nox family of superoxide-producing NADPH oxidases []. It is homologous to the component p67-phox of the phagocytic oxidase, the prototypical Nox [, ]. NOXA1 and NOXO1 support superoxide generation by NOX1 and are expressed predominantly in colon epithelium with NOX1 []. NOXA1 is also coexpressed with NOX2 in some cells, such as endothelial cells, vascular smooth muscle cells, and hematopoietic stem cells [].
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2009-01-15
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3564922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:3826126
Age: embryonic day 14.5
Image: Additional file 4 Noxa1
Specimen Label: Additional file 4 Noxa1
Detected: true
Specimen Num: 1
Publication
First Author: Bánfi B
Year: 2003
Journal: J Biol Chem
Title: Two novel proteins activate superoxide generation by the NADPH oxidase NOX1.
Volume: 278
Issue: 6
Pages: 3510-3
Publication
First Author: Valente AJ
Year: 2007
Journal: Free Radic Biol Med
Title: NOX1 NADPH oxidase regulation by the NOXA1 SH3 domain.
Volume: 43
Issue: 3
Pages: 384-96
Publication
First Author: Kawano M
Year: 2012
Journal: Arch Biochem Biophys
Title: Noxa1 as a moderate activator of Nox2-based NADPH oxidase.
Volume: 519
Issue: 1
Pages: 1-7
Publication
First Author: Ambasta RK
Year: 2006
Journal: Free Radic Biol Med
Title: Noxa1 is a central component of the smooth muscle NADPH oxidase in mice.
Volume: 41
Issue: 2
Pages: 193-201
Publication
First Author: Geiszt M
Year: 2003
Journal: J Biol Chem
Title: Proteins homologous to p47phox and p67phox support superoxide production by NAD(P)H oxidase 1 in colon epithelial cells.
Volume: 278
Issue: 22
Pages: 20006-12
Publication
First Author: Takeya R
Year: 2003
Journal: J Biol Chem
Title: Novel human homologues of p47phox and p67phox participate in activation of superoxide-producing NADPH oxidases.
Volume: 278
Issue: 27
Pages: 25234-46
Publication
First Author: Bedard K
Year: 2007
Journal: Physiol Rev
Title: The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology.
Volume: 87
Issue: 1
Pages: 245-313
Protein
Organism: Mus musculus/domesticus
Length: 444  
Fragment?: false
Publication  
First Author: Vendrov AE
Year: 2019
Journal: Redox Biol
Title: NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis.
Volume: 21
Pages: 101063
Publication
First Author: Flaherty JP
Year: 2010
Journal: Genesis
Title: Generation of a conditional null allele of NADPH oxidase activator 1 (NOXA1).
Volume: 48
Issue: 9
Pages: 568-75
Publication
First Author: Niu XL
Year: 2010
Journal: Circulation
Title: Nox activator 1: a potential target for modulation of vascular reactive oxygen species in atherosclerotic arteries.
Volume: 121
Issue: 4
Pages: 549-59
Publication
First Author: Dutta S
Year: 2010
Journal: PLoS One
Title: Regulation of NOXO1 activity through reversible interactions with p22 and NOXA1.
Volume: 5
Issue: 5
Pages: e10478
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_07
Specimen Label: euxassay_002004_07
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_08
Specimen Label: euxassay_002004_08
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_09
Specimen Label: euxassay_002004_09
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_10
Specimen Label: euxassay_002004_10
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_12
Specimen Label: euxassay_002004_12
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_13
Specimen Label: euxassay_002004_13
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_14
Specimen Label: euxassay_002004_14
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:1681637
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1750323
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826756
Age: embryonic day 14.5
Image: euxassay_002004_15
Specimen Label: euxassay_002004_15
Detected: true
Specimen Num: 8
Publication
First Author: Janus P
Year: 2020
Journal: Cell Death Differ
Title: Pro-death signaling of cytoprotective heat shock factor 1: upregulation of NOXA leading to apoptosis in heat-sensitive cells.
Volume: 27
Issue: 7
Pages: 2280-2292
Publication
First Author: Flodby P
Year: 2016
Journal: Am J Respir Cell Mol Biol
Title: The 78-kD Glucose-Regulated Protein Regulates Endoplasmic Reticulum Homeostasis and Distal Epithelial Cell Survival during Lung Development.
Volume: 55
Issue: 1
Pages: 135-49
Publication
First Author: Hoffman BG
Year: 2008
Journal: Genome Biol
Title: Identification of transcripts with enriched expression in the developing and adult pancreas.
Volume: 9
Issue: 6
Pages: R99
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication        
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication
First Author: Streeter J
Year: 2014
Journal: Circ Res
Title: Phosphorylation of Nox1 regulates association with NoxA1 activation domain.
Volume: 115
Issue: 11
Pages: 911-8
Protein
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: true
Publication
First Author: BelAiba RS
Year: 2007
Journal: Free Radic Biol Med
Title: NOX5 variants are functionally active in endothelial cells.
Volume: 42
Issue: 4
Pages: 446-59
Publication
First Author: Kaito Y
Year: 2014
Journal: FEBS Lett
Title: Nox1 activation by βPix and the role of Ser-340 phosphorylation.
Volume: 588
Issue: 11
Pages: 1997-2002
Publication
First Author: Debbabi M
Year: 2013
Journal: FASEB J
Title: NOXO1 phosphorylation on serine 154 is critical for optimal NADPH oxidase 1 assembly and activation.
Volume: 27
Issue: 4
Pages: 1733-48
Protein Domain
Type: Family
Description: ADPH oxidase 1 (NOX1) is a NADPH oxidase that generates superoxide []. It is involved in several cell functions such as proliferation, vascular contraction, host defence, and cytoskeletal remodelling []. It requires small GTPase Rac, Noxa1 and Noxo1 for its activation []. It can be regulated by betaPix through Rac activation [].
Publication
First Author: Nakano Y
Year: 2007
Journal: Biochem J
Title: Critical roles for p22phox in the structural maturation and subcellular targeting of Nox3.
Volume: 403
Issue: 1
Pages: 97-108
Protein
Organism: Mus musculus/domesticus
Length: 591  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 526  
Fragment?: false