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Search results 1 to 98 out of 98 for Npc1l1

0.036s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Danio rerio
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Wang Y
Year: 2019
Journal: Mol Med Rep
Title: Hepatic NPC1L1 overexpression attenuates alcoholic autophagy in mice.
Volume: 20
Issue: 4
Pages: 3224-3232
Publication    
First Author: Saha P
Year: 2020
Journal: Elife
Title: Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Volume: 9
Publication
First Author: Davies JP
Year: 2005
Journal: J Biol Chem
Title: Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.
Volume: 280
Issue: 13
Pages: 12710-20
Publication
First Author: Temel RE
Year: 2009
Journal: J Lipid Res
Title: Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent.
Volume: 50
Issue: 5
Pages: 915-23
Publication
First Author: Tang W
Year: 2009
Journal: J Lipid Res
Title: Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.
Volume: 50
Issue: 2
Pages: 293-300
Publication  
First Author: Parini P
Year: 2018
Journal: Atherosclerosis
Title: Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption.
Volume: 275
Pages: 246-255
Publication
First Author: Knöpfel M
Year: 2007
Journal: Biochim Biophys Acta
Title: Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
Volume: 1771
Issue: 9
Pages: 1140-7
Publication
First Author: Takada T
Year: 2015
Journal: Sci Transl Med
Title: NPC1L1 is a key regulator of intestinal vitamin K absorption and a modulator of warfarin therapy.
Volume: 7
Issue: 275
Pages: 275ra23
Publication
First Author: Altmann SW
Year: 2004
Journal: Science
Title: Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
Volume: 303
Issue: 5661
Pages: 1201-4
Publication
First Author: Davis HR Jr
Year: 2004
Journal: J Biol Chem
Title: Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Volume: 279
Issue: 32
Pages: 33586-92
Publication
First Author: Tang W
Year: 2011
Journal: Biochim Biophys Acta
Title: Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.
Volume: 1811
Issue: 9
Pages: 549-55
Publication
First Author: Labonté ED
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.
Volume: 295
Issue: 4
Pages: G776-83
Publication
First Author: Tang W
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice.
Volume: 28
Issue: 3
Pages: 448-54
Publication
First Author: Jia L
Year: 2010
Journal: J Lipid Res
Title: Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1.
Volume: 51
Issue: 10
Pages: 3024-33
Publication
First Author: Adams MR
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine.
Volume: 300
Issue: 1
Pages: G164-9
Publication
First Author: Jia L
Year: 2010
Journal: J Lipid Res
Title: Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.
Volume: 51
Issue: 11
Pages: 3135-44
Publication
First Author: Sainz B Jr
Year: 2012
Journal: Nat Med
Title: Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.
Volume: 18
Issue: 2
Pages: 281-5
Publication
First Author: Duval C
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine.
Volume: 340
Issue: 4
Pages: 1259-63
Publication
First Author: Ge L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.
Volume: 108
Issue: 2
Pages: 551-6
Publication
First Author: van der Veen JN
Year: 2005
Journal: J Lipid Res
Title: Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.
Volume: 46
Issue: 3
Pages: 526-34
Publication
First Author: Labonté ED
Year: 2007
Journal: Biochim Biophys Acta
Title: Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.
Volume: 1771
Issue: 9
Pages: 1132-9
Publication
First Author: Li PS
Year: 2014
Journal: Nat Med
Title: The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.
Volume: 20
Issue: 1
Pages: 80-6
Publication
First Author: Yamamoto H
Year: 2019
Journal: Mol Pharmacol
Title: Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice.
Volume: 96
Issue: 1
Pages: 47-55
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lin J
Year: 2017
Journal: Mol Med Rep
Title: Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1.
Volume: 16
Issue: 2
Pages: 1785-1792
Publication
First Author: Xu S
Year: 2011
Journal: Neurosci Lett
Title: Presynaptic impairment in Niemann-Pick C1-deficient neurons: not dependent on presence of glial cells.
Volume: 496
Issue: 1
Pages: 54-9
Publication
First Author: Karten B
Year: 2005
Journal: Biochem J
Title: Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice.
Volume: 387
Issue: Pt 3
Pages: 779-88
Publication
First Author: Zhang YY
Year: 2018
Journal: Science
Title: A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption.
Volume: 360
Issue: 6393
Pages: 1087-1092
Publication
First Author: Davis HR Jr
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.
Volume: 27
Issue: 4
Pages: 841-9
Publication
First Author: Bi X
Year: 2005
Journal: Am J Pathol
Title: Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain.
Volume: 167
Issue: 4
Pages: 1081-92
Publication
First Author: de Vogel-van den Bosch HM
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
Volume: 294
Issue: 5
Pages: G1171-80
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
Publication      
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Protein
Organism: Mus musculus
Length: 1332  
Fragment?: true
Protein
Organism: Mus musculus
Length: 727  
Fragment?: false
Publication
First Author: Wang Y
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Hepatic NPC1L1 promotes hyperlipidemia in LDL receptor deficient mice.
Volume: 499
Issue: 3
Pages: 626-633
UniProt Feature
Begin: 164
Description: Required for interaction with NPC1L1
Type: short sequence motif
End: 166
Publication
First Author: Xie C
Year: 2012
Journal: J Lipid Res
Title: Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.
Volume: 53
Issue: 10
Pages: 2092-101
Publication
First Author: Valasek MA
Year: 2007
Journal: J Lipid Res
Title: Fenofibrate reduces intestinal cholesterol absorption via PPARalpha-dependent modulation of NPC1L1 expression in mouse.
Volume: 48
Issue: 12
Pages: 2725-35
Publication
First Author: Toyoda Y
Year: 2019
Journal: FASEB Bioadv
Title: Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery.
Volume: 1
Issue: 5
Pages: 283-295
Publication
First Author: Kurano M
Year: 2012
Journal: J Lipid Res
Title: Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver.
Volume: 53
Issue: 11
Pages: 2275-85
Publication
First Author: Xie P
Year: 2014
Journal: Atherosclerosis
Title: Genetic demonstration of intestinal NPC1L1 as a major determinant of hepatic cholesterol and blood atherogenic lipoprotein levels.
Volume: 237
Issue: 2
Pages: 609-17
Publication
First Author: Kim YC
Year: 2019
Journal: Gastroenterology
Title: Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption.
Volume: 156
Issue: 4
Pages: 1052-1065
Publication
First Author: Kwon HJ
Year: 2011
Journal: PLoS One
Title: The structure of the NPC1L1 N-terminal domain in a closed conformation.
Volume: 6
Issue: 4
Pages: e18722
Publication
First Author: Kung CP
Year: 2016
Journal: Cell Rep
Title: The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction.
Volume: 14
Issue: 10
Pages: 2413-25
Publication
First Author: Nassir F
Year: 2007
Journal: J Biol Chem
Title: CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine.
Volume: 282
Issue: 27
Pages: 19493-501
Publication
First Author: Dixit SS
Year: 2007
Journal: Biochem J
Title: Do mammalian NPC1 and NPC2 play a role in intestinal cholesterol absorption?
Volume: 408
Issue: 1
Pages: 1-5
Publication
First Author: Ratliff EP
Year: 2006
Journal: J Lipid Res
Title: Transgenic expression of CYP7A1 in LDL receptor-deficient mice blocks diet-induced hypercholesterolemia.
Volume: 47
Issue: 7
Pages: 1513-20
Publication
First Author: Rong S
Year: 2017
Journal: J Lipid Res
Title: Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine.
Volume: 58
Issue: 10
Pages: 1988-1998
Publication
First Author: Wang HH
Year: 2007
Journal: Hepatology
Title: Quantifying anomalous intestinal sterol uptake, lymphatic transport, and biliary secretion in Abcg8(-/-) mice.
Volume: 45
Issue: 4
Pages: 998-1006
Publication
First Author: Hagita S
Year: 2018
Journal: Sci Rep
Title: Transcriptional control of intestinal cholesterol absorption, adipose energy expenditure and lipid handling by Sortilin.
Volume: 8
Issue: 1
Pages: 9006
Publication
First Author: Hager L
Year: 2012
Journal: J Biol Chem
Title: Lecithin:cholesterol acyltransferase deficiency protects against cholesterol-induced hepatic endoplasmic reticulum stress in mice.
Volume: 287
Issue: 24
Pages: 20755-68
Publication
First Author: Zhou L
Year: 2014
Journal: J Biol Chem
Title: Up-regulation of cholesterol absorption is a mechanism for cholecystokinin-induced hypercholesterolemia.
Volume: 289
Issue: 19
Pages: 12989-99
Publication
First Author: Temel RE
Year: 2007
Journal: J Clin Invest
Title: Hepatic Niemann-Pick C1-like 1 regulates biliary cholesterol concentration and is a target of ezetimibe.
Volume: 117
Issue: 7
Pages: 1968-78
Publication
First Author: Li Z
Year: 2009
Journal: Biochim Biophys Acta
Title: Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
Volume: 1791
Issue: 4
Pages: 297-306
Publication
First Author: Sui Y
Year: 2015
Journal: Mol Endocrinol
Title: Intestinal pregnane X receptor links xenobiotic exposure and hypercholesterolemia.
Volume: 29
Issue: 5
Pages: 765-76
Publication
First Author: Ravid Z
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Modulation of intestinal cholesterol absorption by high glucose levels: impact on cholesterol transporters, regulatory enzymes, and transcription factors.
Volume: 295
Issue: 5
Pages: G873-85
Publication
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7