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Search results 1 to 100 out of 111 for Npc1l1

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Type Details Score
Gene
29881 | NPC1L1
Type: gene
Organism: human
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Gene
432367 | Npc1l1
Type: gene
Organism: rat
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Gene
463381 | NPC1L1
Type: gene
Organism: chimpanzee
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Gene
610398 | NPC1L1
Type: gene
Organism: dog, domestic
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Gene
539550 | NPC1L1
Type: gene
Organism: cattle
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Gene
100616532 | npc1l1
Type: gene
Organism: zebrafish
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Gene
699235 | NPC1L1
Type: gene
Organism: macaque, rhesus
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Gene
100487339 | npc1l1
Type: gene
Organism: frog, western clawed
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Protein Coding Gene
MGI:2685089 | Npc1l1
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
25881076 | J:317864
 
First Author: He J
Year: 2015
Journal: BMC Cancer
Title: NPC1L1 knockout protects against colitis-associated tumorigenesis in mice.
Volume: 15
Pages: 189
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Publication
31432115 | J:289936
First Author: Wang Y
Year: 2019
Journal: Mol Med Rep
Title: Hepatic NPC1L1 overexpression attenuates alcoholic autophagy in mice.
Volume: 20
Issue: 4
Pages: 3224-3232
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Publication
32410728 | J:305624
   
First Author: Saha P
Year: 2020
Journal: Elife
Title: Inter-domain dynamics drive cholesterol transport by NPC1 and NPC1L1 proteins.
Volume: 9
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Publication
15671032 | J:98568
First Author: Davies JP
Year: 2005
Journal: J Biol Chem
Title: Inactivation of NPC1L1 causes multiple lipid transport defects and protects against diet-induced hypercholesterolemia.
Volume: 280
Issue: 13
Pages: 12710-20
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Publication
19141868 | J:149640
First Author: Temel RE
Year: 2009
Journal: J Lipid Res
Title: Diosgenin stimulation of fecal cholesterol excretion in mice is not NPC1L1 dependent.
Volume: 50
Issue: 5
Pages: 915-23
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Publication
18796403 | J:149007
First Author: Tang W
Year: 2009
Journal: J Lipid Res
Title: Genetic inactivation of NPC1L1 protects against sitosterolemia in mice lacking ABCG5/ABCG8.
Volume: 50
Issue: 2
Pages: 293-300
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Publication
17689140 | J:127076
First Author: Knöpfel M
Year: 2007
Journal: Biochim Biophys Acta
Title: Multiple plasma membrane receptors but not NPC1L1 mediate high-affinity, ezetimibe-sensitive cholesterol uptake into the intestinal brush border membrane.
Volume: 1771
Issue: 9
Pages: 1140-7
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Publication
29980051 | J:289237
 
First Author: Parini P
Year: 2018
Journal: Atherosclerosis
Title: Overexpression of transforming growth factor β induced factor homeobox 1 represses NPC1L1 and lowers markers of intestinal cholesterol absorption.
Volume: 275
Pages: 246-255
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Publication
25696002 | J:233997
First Author: Takada T
Year: 2015
Journal: Sci Transl Med
Title: NPC1L1 is a key regulator of intestinal vitamin K absorption and a modulator of warfarin therapy.
Volume: 7
Issue: 275
Pages: 275ra23
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Publication
34943976 | J:317738
 
First Author: Jia L
Year: 2021
Journal: Cells
Title: NPC1L1 Deficiency Suppresses Ileal Fibroblast Growth Factor 15 Expression and Increases Bile Acid Pool Size in High-Fat-Diet-Fed Mice.
Volume: 10
Issue: 12
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Publication
14976318 | J:89712
First Author: Altmann SW
Year: 2004
Journal: Science
Title: Niemann-Pick C1 Like 1 protein is critical for intestinal cholesterol absorption.
Volume: 303
Issue: 5661
Pages: 1201-4
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Publication
15173162 | J:121206
First Author: Davis HR Jr
Year: 2004
Journal: J Biol Chem
Title: Niemann-Pick C1 Like 1 (NPC1L1) is the intestinal phytosterol and cholesterol transporter and a key modulator of whole-body cholesterol homeostasis.
Volume: 279
Issue: 32
Pages: 33586-92
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Publication
34465831 | J:312902
First Author: Ge H
Year: 2021
Journal: Sci Rep
Title: Phytosterol accumulation results in ventricular arrhythmia, impaired cardiac function and death in mice.
Volume: 11
Issue: 1
Pages: 17449
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Publication
21071508 | J:168503
First Author: Adams MR
Year: 2011
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Use of NBD-cholesterol to identify a minor but NPC1L1-independent cholesterol absorption pathway in mouse intestine.
Volume: 300
Issue: 1
Pages: G164-9
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Publication
20699423 | J:165600
First Author: Jia L
Year: 2010
Journal: J Lipid Res
Title: Niemann-Pick C1-Like 1 deletion in mice prevents high-fat diet-induced fatty liver by reducing lipogenesis.
Volume: 51
Issue: 11
Pages: 3135-44
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Publication
18718999 | J:142281
First Author: Labonté ED
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Reduced absorption of saturated fatty acids and resistance to diet-induced obesity and diabetes by ezetimibe-treated and Npc1l1-/- mice.
Volume: 295
Issue: 4
Pages: G776-83
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Publication
21683156 | J:177621
First Author: Tang W
Year: 2011
Journal: Biochim Biophys Acta
Title: Ezetimibe restores biliary cholesterol excretion in mice expressing Niemann-Pick C1-Like 1 only in liver.
Volume: 1811
Issue: 9
Pages: 549-55
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Publication
20601625 | J:165455
First Author: Jia L
Year: 2010
Journal: J Lipid Res
Title: Dietary cholesterol reverses resistance to diet-induced weight gain in mice lacking Niemann-Pick C1-Like 1.
Volume: 51
Issue: 10
Pages: 3024-33
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Publication
18187667 | J:159818
First Author: Tang W
Year: 2008
Journal: Arterioscler Thromb Vasc Biol
Title: Niemann-Pick C1-like 1 is required for an LXR agonist to raise plasma HDL cholesterol in mice.
Volume: 28
Issue: 3
Pages: 448-54
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Publication
22231557 | J:181208
First Author: Sainz B Jr
Year: 2012
Journal: Nat Med
Title: Identification of the Niemann-Pick C1-like 1 cholesterol absorption receptor as a new hepatitis C virus entry factor.
Volume: 18
Issue: 2
Pages: 281-5
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Publication
16414355 | J:104982
First Author: Duval C
Year: 2006
Journal: Biochem Biophys Res Commun
Title: Niemann-Pick C1 like 1 gene expression is down-regulated by LXR activators in the intestine.
Volume: 340
Issue: 4
Pages: 1259-63
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Publication
21187433 | J:168682
First Author: Ge L
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Flotillins play an essential role in Niemann-Pick C1-like 1-mediated cholesterol uptake.
Volume: 108
Issue: 2
Pages: 551-6
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Publication
17442616 | J:127024
First Author: Labonté ED
Year: 2007
Journal: Biochim Biophys Acta
Title: Class B type I scavenger receptor is responsible for the high affinity cholesterol binding activity of intestinal brush border membrane vesicles.
Volume: 1771
Issue: 9
Pages: 1132-9
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Publication
15604518 | J:96527
First Author: van der Veen JN
Year: 2005
Journal: J Lipid Res
Title: Reduced cholesterol absorption upon PPARdelta activation coincides with decreased intestinal expression of NPC1L1.
Volume: 46
Issue: 3
Pages: 526-34
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Publication
24336247 | J:226578
First Author: Li PS
Year: 2014
Journal: Nat Med
Title: The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.
Volume: 20
Issue: 1
Pages: 80-6
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Publication
31064810 | J:289615
First Author: Yamamoto H
Year: 2019
Journal: Mol Pharmacol
Title: Hepatic Expression of Niemann-Pick C1-Like 1, a Cholesterol Reabsorber from Bile, Exacerbates Western Diet-Induced Atherosclerosis in LDL Receptor Mutant Mice.
Volume: 96
Issue: 1
Pages: 47-55
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Protein Coding Gene
MGP_CAROLIEiJ_G0016068 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0018017 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0017990 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0017954 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0017958 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0017771 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685089 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0018410 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0017333 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0017746 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0017856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0017848 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0017927 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0017874 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0018450 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0017113 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0017387 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016823 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0016910 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
21507342 | J:173215
First Author: Xu S
Year: 2011
Journal: Neurosci Lett
Title: Presynaptic impairment in Niemann-Pick C1-deficient neurons: not dependent on presence of glial cells.
Volume: 496
Issue: 1
Pages: 54-9
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Publication
15544574 | J:117523
First Author: Karten B
Year: 2005
Journal: Biochem J
Title: Generation and function of astroglial lipoproteins from Niemann-Pick type C1-deficient mice.
Volume: 387
Issue: Pt 3
Pages: 779-88
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Publication
28627641 | J:271944
First Author: Lin J
Year: 2017
Journal: Mol Med Rep
Title: Osteopontin deficiency protects mice from cholesterol gallstone formation by reducing expression of intestinal NPC1L1.
Volume: 16
Issue: 2
Pages: 1785-1792
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Publication
29880681 | J:263730
First Author: Zhang YY
Year: 2018
Journal: Science
Title: A LIMA1 variant promotes low plasma LDL cholesterol and decreases intestinal cholesterol absorption.
Volume: 360
Issue: 6393
Pages: 1087-1092
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Publication
17218600 | J:135062
First Author: Davis HR Jr
Year: 2007
Journal: Arterioscler Thromb Vasc Biol
Title: Deficiency of Niemann-Pick C1 Like 1 prevents atherosclerosis in ApoE-/- mice.
Volume: 27
Issue: 4
Pages: 841-9
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Publication
16192643 | J:101694
First Author: Bi X
Year: 2005
Journal: Am J Pathol
Title: Deregulation of the phosphatidylinositol-3 kinase signaling cascade is associated with neurodegeneration in Npc1-/- mouse brain.
Volume: 167
Issue: 4
Pages: 1081-92
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Publication
18356535 | J:136627
First Author: de Vogel-van den Bosch HM
Year: 2008
Journal: Am J Physiol Gastrointest Liver Physiol
Title: A cholesterol-free, high-fat diet suppresses gene expression of cholesterol transporters in murine small intestine.
Volume: 294
Issue: 5
Pages: G1171-80
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Publication
- | J:94790
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Mouse Synonym Curation
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:157065
     
First Author: Helmholtz Zentrum Muenchen GmbH
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu)
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:155856
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
A2RRR0
Organism: Mus musculus/domesticus
Length: 727  
Fragment?: false
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Protein
A3KMG9
Organism: Mus musculus/domesticus
Length: 1332  
Fragment?: true
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Publication
29601818 | J:270602
First Author: Wang Y
Year: 2018
Journal: Biochem Biophys Res Commun
Title: Hepatic NPC1L1 promotes hyperlipidemia in LDL receptor deficient mice.
Volume: 499
Issue: 3
Pages: 626-633
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UniProt Feature
UniProt Feature
Begin: 164
Description: Required for interaction with NPC1L1
Type: short sequence motif
End: 166
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Publication
17726195 | J:129975
First Author: Valasek MA
Year: 2007
Journal: J Lipid Res
Title: Fenofibrate reduces intestinal cholesterol absorption via PPARalpha-dependent modulation of NPC1L1 expression in mouse.
Volume: 48
Issue: 12
Pages: 2725-35
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Publication
32123832 | J:283890
First Author: Toyoda Y
Year: 2019
Journal: FASEB Bioadv
Title: Identification of hepatic NPC1L1 as an NAFLD risk factor evidenced by ezetimibe-mediated steatosis prevention and recovery.
Volume: 1
Issue: 5
Pages: 283-295
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Publication
22811412 | J:188044
First Author: Xie C
Year: 2012
Journal: J Lipid Res
Title: Ezetimibe blocks the internalization of NPC1L1 and cholesterol in mouse small intestine.
Volume: 53
Issue: 10
Pages: 2092-101
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Publication
22891292 | J:190570
First Author: Kurano M
Year: 2012
Journal: J Lipid Res
Title: Modulation of lipid metabolism with the overexpression of NPC1L1 in mouse liver.
Volume: 53
Issue: 11
Pages: 2275-85
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Publication
25463095 | J:257065
First Author: Xie P
Year: 2014
Journal: Atherosclerosis
Title: Genetic demonstration of intestinal NPC1L1 as a major determinant of hepatic cholesterol and blood atherogenic lipoprotein levels.
Volume: 237
Issue: 2
Pages: 609-17
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Publication
30521806 | J:295567
First Author: Kim YC
Year: 2019
Journal: Gastroenterology
Title: Small Heterodimer Partner and Fibroblast Growth Factor 19 Inhibit Expression of NPC1L1 in Mouse Intestine and Cholesterol Absorption.
Volume: 156
Issue: 4
Pages: 1052-1065
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Publication
21525977 | -
First Author: Kwon HJ
Year: 2011
Journal: PLoS One
Title: The structure of the NPC1L1 N-terminal domain in a closed conformation.
Volume: 6
Issue: 4
Pages: e18722
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Publication
26947067 | J:234350
First Author: Kung CP
Year: 2016
Journal: Cell Rep
Title: The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction.
Volume: 14
Issue: 10
Pages: 2413-25
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Publication
37943936 | J:342939
First Author: Ferrari A
Year: 2023
Journal: Science
Title: Aster-dependent nonvesicular transport facilitates dietary cholesterol uptake.
Volume: 382
Issue: 6671
Pages: eadf0966
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Publication
17507371 | J:123605
First Author: Nassir F
Year: 2007
Journal: J Biol Chem
Title: CD36 is important for fatty acid and cholesterol uptake by the proximal but not distal intestine.
Volume: 282
Issue: 27
Pages: 19493-501
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Publication
19416652 | J:148766
First Author: Li Z
Year: 2009
Journal: Biochim Biophys Acta
Title: Serine palmitoyltransferase (SPT) deficient mice absorb less cholesterol.
Volume: 1791
Issue: 4
Pages: 297-306
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Publication
28630260 | J:245647
First Author: Rong S
Year: 2017
Journal: J Lipid Res
Title: Cholesterol auxotrophy and intolerance to ezetimibe in mice with SREBP-2 deficiency in the intestine.
Volume: 58
Issue: 10
Pages: 1988-1998
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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