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Search results 1 to 100 out of 118 for Nphp3

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
27031 | NPHP3
Type: gene
Organism: human
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Gene
780190 | nphp3
Type: gene
Organism: frog, western clawed
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Gene
363126 | Nphp3
Type: gene
Organism: rat
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Gene
460706 | NPHP3
Type: gene
Organism: chimpanzee
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Gene
507522 | NPHP3
Type: gene
Organism: cattle
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Gene
100856544 | NPHP3
Type: gene
Organism: dog, domestic
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Gene
420690 | NPHP3
Type: gene
Organism: chicken
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Gene
562601 | nphp3
Type: gene
Organism: zebrafish
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Gene
717622 | NPHP3
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1921275 | Nphp3
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
348808 | NPHP3-AS1
Type: gene
Organism: human
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Publication
22328406 | J:222989
First Author: Nakata K
Year: 2012
Journal: Cytoskeleton (Hoboken)
Title: Targeting of Nphp3 to the primary cilia is controlled by an N-terminal myristoylation site and coiled-coil domains.
Volume: 69
Issue: 4
Pages: 221-34
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Publication
20169535 | J:212148
First Author: Shiba D
Year: 2010
Journal: Cytoskeleton (Hoboken)
Title: Inv acts as a molecular anchor for Nphp3 and Nek8 in the proximal segment of primary cilia.
Volume: 67
Issue: 2
Pages: 112-9
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Publication
24178445 | J:222987
First Author: Yamaguchi T
Year: 2014
Journal: Lipids
Title: Renal cyclooxygenase products are higher and lipoxygenase products are lower in early disease in the pcy mouse model of adolescent nephronophthisis.
Volume: 49
Issue: 1
Pages: 39-47
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Publication
12872122 | J:91453
First Author: Olbrich H
Year: 2003
Journal: Nat Genet
Title: Mutations in a novel gene, NPHP3, cause adolescent nephronophthisis, tapeto-retinal degeneration and hepatic fibrosis.
Volume: 34
Issue: 4
Pages: 455-9
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Publication
18371931 | J:139258
First Author: Bergmann C
Year: 2008
Journal: Am J Hum Genet
Title: Loss of nephrocystin-3 function can cause embryonic lethality, Meckel-Gruber-like syndrome, situs inversus, and renal-hepatic-pancreatic dysplasia.
Volume: 82
Issue: 4
Pages: 959-70
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Publication
11134256 | J:67229
First Author: Omran H
Year: 2001
Journal: J Am Soc Nephrol
Title: Human adolescent nephronophthisis: gene locus synteny with polycystic kidney disease in pcy mice.
Volume: 12
Issue: 1
Pages: 107-13
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Publication
29395339 | J:261989
First Author: Nakajima Y
Year: 2018
Journal: Kidney Int
Title: The Inv compartment of renal cilia is an intraciliary signal-activating center to phosphorylate ANKS6.
Volume: 93
Issue: 5
Pages: 1108-1117
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Publication
17884984 | J:222988
First Author: Beckers A
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The mouse homeobox gene Noto regulates node morphogenesis, notochordal ciliogenesis, and left right patterning.
Volume: 104
Issue: 40
Pages: 15765-70
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DO Term
DOID:0111114 | nephronophthisis 3
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Protein Coding Gene
MGP_CAROLIEiJ_G0032593 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0035202 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0035182 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0035114 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0035175 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0034885 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1921275 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0035695 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0034197 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0034854 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035015 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0034963 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035091 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035002 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0035717 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0033904 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0034317 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0015461 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0033739 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
3712587 | J:8302
First Author: Takahashi H
Year: 1986
Journal: J Urol
Title: A new mouse model of genetically transmitted polycystic kidney disease.
Volume: 135
Issue: 6
Pages: 1280-3
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Publication
21633408 | J:194720
First Author: Chen NX
Year: 2011
Journal: Kidney Int
Title: Calcimimetics inhibit renal pathology in rodent nephronophthisis.
Volume: 80
Issue: 6
Pages: 612-9
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Publication
8636651 | J:129264
First Author: Gattone VH 2nd
Year: 1996
Journal: J Lab Clin Med
Title: Renal expression of a transforming growth factor-alpha transgene accelerates the progression of inherited, slowly progressive polycystic kidney disease in the mouse.
Volume: 127
Issue: 2
Pages: 214-22
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Publication
8094982 | J:11914
First Author: Nakamura T
Year: 1993
Journal: J Am Soc Nephrol
Title: Growth factor gene expression in kidney of murine polycystic kidney disease.
Volume: 3
Issue: 7
Pages: 1378-86
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Publication
18185504 | J:152880
First Author: Wallace DP
Year: 2008
Journal: Kidney Int
Title: Tracking kidney volume in mice with polycystic kidney disease by magnetic resonance imaging.
Volume: 73
Issue: 6
Pages: 778-81
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Publication
1385849 | J:2203
First Author: Aukema HM
Year: 1992
Journal: Lipids
Title: Abnormal lipid and fatty acid compositions of kidneys from mice with polycystic kidney disease.
Volume: 27
Issue: 6
Pages: 429-35
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Publication
10480021 | J:58029
First Author: Kaneta S
Year: 1999
Journal: Exp Anim
Title: Renal carbonic anhydrase activity in DBA/2FG-pcy/pcy mice with inherited polycystic kidney disease.
Volume: 48
Issue: 3
Pages: 161-9
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Publication
7919157 | J:19339
First Author: Kawa G
Year: 1994
Journal: J Am Soc Nephrol
Title: Sodium pump distribution is not reversed in the DBA/2FG-pcy, polycystic kidney disease model mouse.
Volume: 4
Issue: 12
Pages: 2040-9
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Publication
7539536 | J:24112
First Author: Ebihara I
Year: 1995
Journal: Ren Physiol Biochem
Title: Altered extracellular matrix component gene expression in murine polycystic kidney.
Volume: 18
Issue: 2
Pages: 73-80
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Publication
1881263 | J:27285
First Author: Towner RA
Year: 1991
Journal: Magn Reson Imaging
Title: In vivo proton magnetic resonance imaging and localized spectroscopic analysis of polycystic kidney disease in DBA/2FG-pyc mice.
Volume: 9
Issue: 3
Pages: 429-34
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Publication
9329956 | J:44580
First Author: Woo DD
Year: 1997
Journal: J Clin Invest
Title: Genetic identification of two major modifier loci of polycystic kidney disease progression in pcy mice.
Volume: 100
Issue: 8
Pages: 1934-40
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Publication
12009430 | J:76744
First Author: Cuozzo FP
Year: 2002
Journal: Biochim Biophys Acta
Title: Overexpression of kidney phosphatidylinositol 4-kinasebeta and phospholipase C(gamma1) proteins in two rodent models of polycystic kidney disease.
Volume: 1587
Issue: 1
Pages: 99-106
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Publication
23852700 | J:202627
First Author: Ruh H
Year: 2013
Journal: J Lipid Res
Title: MALDI imaging MS reveals candidate lipid markers of polycystic kidney disease.
Volume: 54
Issue: 10
Pages: 2785-94
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GXD Expression
GXD Expression
     
Probe: MGI:3827128
Assay Type: Western blot
Annotation Date: 2009-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3827130
Age: embryonic day 12.5
Specimen Label: ko/wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3827128
Assay Type: Western blot
Annotation Date: 2009-01-20
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3827130
Age: embryonic day 12.5
Specimen Label: ko/ko
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3827128
Assay Type: Western blot
Annotation Date: 2009-01-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603920
Stage: TS20
Assay Id: MGI:3827130
Age: embryonic day 12.5
Specimen Label: wt/wt
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6781702
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3673015
Stage: TS15
Assay Id: MGI:6781750
Age: embryonic day 9.5
Specimen Label: pSHF
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6781702
Assay Type: RT-PCR
Annotation Date: 2021-10-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603915
Stage: TS15
Assay Id: MGI:6781750
Age: embryonic day 9.5
Specimen Label: embryo
Detected: true
Specimen Num: 2
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Publication
24815352 | J:211661
First Author: Galarreta CI
Year: 2014
Journal: Am J Pathol
Title: Tubular obstruction leads to progressive proximal tubular injury and atubular glomeruli in polycystic kidney disease.
Volume: 184
Issue: 7
Pages: 1957-66
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Publication
7622841 | J:27468
First Author: Ogborn MR
Year: 1995
Journal: J Histochem Cytochem
Title: Renal tubule Na,K-ATPase polarity in different animal models of polycystic kidney disease.
Volume: 43
Issue: 8
Pages: 785-90
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Publication
7559658 | J:29463
First Author: Maxwell MM
Year: 1995
Journal: J Biol Chem
Title: Ke 6 gene. Sequence and organization and aberrant regulation in murine polycystic kidney disease.
Volume: 270
Issue: 42
Pages: 25213-9
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Publication
31928223 | J:324733
First Author: Takenaka T
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Klotho supplementation ameliorates blood pressure and renal function in DBA/2-pcy mice, a model of polycystic kidney disease.
Volume: 318
Issue: 3
Pages: F557-F564
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Publication
28522687 | J:291498
First Author: Raman A
Year: 2017
Journal: J Am Soc Nephrol
Title: Integrin-Linked Kinase Signaling Promotes Cyst Growth and Fibrosis in Polycystic Kidney Disease.
Volume: 28
Issue: 9
Pages: 2708-2719
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Publication
24284511 | J:323152
First Author: Wallace DP
Year: 2014
Journal: Kidney Int
Title: Periostin promotes renal cyst growth and interstitial fibrosis in polycystic kidney disease.
Volume: 85
Issue: 4
Pages: 845-54
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Publication
28630289 | J:244827
First Author: Ciolek J
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: Green mamba peptide targets type-2 vasopressin receptor against polycystic kidney disease.
Volume: 114
Issue: 27
Pages: 7154-7159
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Publication
8144700 | J:18532
 
First Author: Avner ED
Year: 1993
Journal: J Cell Sci Suppl
Title: Epithelial polarity and differentiation in polycystic kidney disease.
Volume: 17
Pages: 217-22
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Publication
7661851 | J:27987
First Author: Aziz N
Year: 1995
Journal: Bioessays
Title: Animal models of polycystic kidney disease.
Volume: 17
Issue: 8
Pages: 703-12
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Publication
20562878 | J:162080
First Author: Natoli TA
Year: 2010
Journal: Nat Med
Title: Inhibition of glucosylceramide accumulation results in effective blockade of polycystic kidney disease in mouse models.
Volume: 16
Issue: 7
Pages: 788-92
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Publication
1883968 | J:11399
First Author: Takahashi H
Year: 1991
Journal: J Am Soc Nephrol
Title: A hereditary model of slowly progressive polycystic kidney disease in the mouse.
Volume: 1
Issue: 7
Pages: 980-9
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Publication
20554900 | J:162084
First Author: Ahmadie R
Year: 2010
Journal: J Nutr
Title: A high-lipid diet potentiates left ventricular dysfunction in nitric oxide synthase 3-deficient mice after chronic pressure overload.
Volume: 140
Issue: 8
Pages: 1438-44
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Publication
7927664 | J:20463
First Author: Gessner A
Year: 1994
Journal: Infect Immun
Title: Recombinant soluble interleukin-4 (IL-4) receptor acts as an antagonist of IL-4 in murine cutaneous Leishmaniasis.
Volume: 62
Issue: 10
Pages: 4112-7
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Publication
22832925 | J:188633
First Author: Ghosh AK
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: 3D spheroid defects in NPHP knockdown cells are rescued by the somatostatin receptor agonist octreotide.
Volume: 303
Issue: 8
Pages: F1225-9
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Publication
1748176 | J:2956
First Author: Nagao S
Year: 1991
Journal: Jikken Dobutsu
Title: Linkage analysis of two murine polycystic kidney disease genes, pcy and cpk.
Volume: 40
Issue: 4
Pages: 557-60
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Publication
8825940 | J:30811
First Author: Nagao S
Year: 1995
Journal: Biochem Genet
Title: Genetic mapping of the polycystic kidney gene, pcy, on mouse chromosome 9.
Volume: 33
Issue: 11-12
Pages: 401-12
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Publication
9263671 | J:43895
First Author: Griffin MD
Year: 1997
Journal: Curr Opin Nephrol Hypertens
Title: Cystic kidney diseases.
Volume: 6
Issue: 3
Pages: 276-83
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Publication
28205547 | J:244067
 
First Author: Hajarnis S
Year: 2017
Journal: Nat Commun
Title: microRNA-17 family promotes polycystic kidney disease progression through modulation of mitochondrial metabolism.
Volume: 8
Pages: 14395
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Publication
14600027 | J:87130
First Author: Guay-Woodford LM
Year: 2003
Journal: Am J Physiol Renal Physiol
Title: Murine models of polycystic kidney disease: molecular and therapeutic insights.
Volume: 285
Issue: 6
Pages: F1034-49
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Publication
22357932 | J:182741
First Author: Alten L
Year: 2012
Journal: Development
Title: Differential regulation of node formation, nodal ciliogenesis and cilia positioning by Noto and Foxj1.
Volume: 139
Issue: 7
Pages: 1276-84
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Publication
27582005 | J:235788
First Author: Nagy II
Year: 2016
Journal: BMC Dev Biol
Title: Impairment of Wnt11 function leads to kidney tubular abnormalities and secondary glomerular cystogenesis.
Volume: 16
Issue: 1
Pages: 30
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Publication
27340223 | J:237132
First Author: Burnicka-Turek O
Year: 2016
Journal: Hum Mol Genet
Title: Cilia gene mutations cause atrioventricular septal defects by multiple mechanisms.
Volume: 25
Issue: 14
Pages: 3011-3028
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Protein
Q14BM5
Organism: Mus musculus/domesticus
Length: 1204  
Fragment?: false
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Publication
- | J:104190
     
First Author: The Australian Phenomics Facility at The Australian National University
Year: 2006
Journal: MGI Direct Data Submission
Title: Heritable mouse mutants from the ENU mutagenesis program at the Australian Phenomics Facility at The Australian National University
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Publication
- | J:188991
     
First Author: The Jackson Laboratory
Year: 2012
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by The Jackson Laboratory
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:342587
       
First Author: AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators
Year: 2011
Title: Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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