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Search results 1 to 100 out of 538 for Nphs2

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0.068s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Koehler S
Year: 2017
Journal: Kidney Int
Title: Construction of a viral T2A-peptide based knock-in mouse model for enhanced Cre recombinase activity and fluorescent labeling of podocytes.
Volume: 91
Issue: 6
Pages: 1510-1517
Publication
First Author: Pozzi A
Year: 2008
Journal: Dev Biol
Title: Beta1 integrin expression by podocytes is required to maintain glomerular structural integrity.
Volume: 316
Issue: 2
Pages: 288-301
Publication
First Author: Hou G
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: Ret is critical for podocyte survival following glomerular injury in vivo.
Volume: 308
Issue: 7
Pages: F774-83
Publication
First Author: Schell C
Year: 2015
Journal: PLoS One
Title: Podocyte-Specific Deletion of Murine CXADR Does Not Impair Podocyte Development, Function or Stress Response.
Volume: 10
Issue: 6
Pages: e0129424
Publication
First Author: Guo B
Year: 2018
Journal: J Am Soc Nephrol
Title: Serum Response Factor Is Essential for Maintenance of Podocyte Structure and Function.
Volume: 29
Issue: 2
Pages: 416-422
Publication
First Author: Schell C
Year: 2017
Journal: Proc Natl Acad Sci U S A
Title: The FERM protein EPB41L5 regulates actomyosin contractility and focal adhesion formation to maintain the kidney filtration barrier.
Volume: 114
Issue: 23
Pages: E4621-E4630
Publication
First Author: Refaeli I
Year: 2020
Journal: Sci Rep
Title: Distinct Functional Requirements for Podocalyxin in Immature and Mature Podocytes Reveal Mechanisms of Human Kidney Disease.
Volume: 10
Issue: 1
Pages: 9419
Publication
First Author: Nilsson D
Year: 2019
Journal: Physiol Rep
Title: Foxc2 is essential for podocyte function.
Volume: 7
Issue: 9
Pages: e14083
Publication
First Author: Wanner N
Year: 2019
Journal: J Am Soc Nephrol
Title: DNA Methyltransferase 1 Controls Nephron Progenitor Cell Renewal and Differentiation.
Volume: 30
Issue: 1
Pages: 63-78
Publication
First Author: Jeansson M
Year: 2011
Journal: J Clin Invest
Title: Angiopoietin-1 is essential in mouse vasculature during development and in response to injury.
Volume: 121
Issue: 6
Pages: 2278-89
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the EUCOMM and EUCOMMTools projects by the Wellcome Trust Sanger Institute
Allele
Name: nephrosis 2, podocin; targeted mutation 1, Shanghai Model Organisms Center
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Allele
Name: transgene insertion 295, Lawrence B Holzman
Allele Type: Transgenic
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant strain, transgenic, congenic
Strain
Attribute String: congenic, transgenic
Publication
First Author: Balkawade RS
Year: 2019
Journal: Am J Physiol Renal Physiol
Title: Podocyte-specific expression of Cre recombinase promotes glomerular basement membrane thickening.
Volume: 316
Issue: 5
Pages: F1026-F1040
Publication
First Author: Boucher I
Year: 2012
Journal: Lab Invest
Title: Gα12 activation in podocytes leads to cumulative changes in glomerular collagen expression, proteinuria and glomerulosclerosis.
Volume: 92
Issue: 5
Pages: 662-75
Publication
First Author: Kaufman L
Year: 2010
Journal: J Biol Chem
Title: Up-regulation of the homophilic adhesion molecule sidekick-1 in podocytes contributes to glomerulosclerosis.
Volume: 285
Issue: 33
Pages: 25677-85
Publication
First Author: Moeller MJ
Year: 2005
Journal: Am J Physiol Renal Physiol
Title: An efficient system for tissue-specific overexpression of transgenes in podocytes in vivo.
Volume: 289
Issue: 2
Pages: F481-8
Genotype
Symbol: Tg(NPHS2-cre)295Lbh/?
Background: 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
Zygosity: ot
Has Mutant Allele: true
Genotype
Symbol: Tg(NPHS2-cre)295Lbh/Tg(NPHS2-cre)295Lbh
Background: 129S6.Cg-Tg(NPHS2-cre)295Lbh/BroJ
Zygosity: hm
Has Mutant Allele: true
Publication
First Author: Papeta N
Year: 2009
Journal: J Clin Invest
Title: Susceptibility loci for murine HIV-associated nephropathy encode trans-regulators of podocyte gene expression.
Volume: 119
Issue: 5
Pages: 1178-88
Publication
First Author: Philippe A
Year: 2008
Journal: Kidney Int
Title: A missense mutation in podocin leads to early and severe renal disease in mice.
Volume: 73
Issue: 9
Pages: 1038-47
Publication
First Author: Roselli S
Year: 2002
Journal: Am J Pathol
Title: Podocin localizes in the kidney to the slit diaphragm area.
Volume: 160
Issue: 1
Pages: 131-9
Publication
First Author: Tabatabaeifar M
Year: 2017
Journal: PLoS One
Title: An inducible mouse model of podocin-mutation-related nephrotic syndrome.
Volume: 12
Issue: 10
Pages: e0186574
Publication
First Author: Wang J
Year: 2010
Journal: Genesis
Title: Tamoxifen-inducible podocyte-specific iCre recombinase transgenic mouse provides a simple approach for modulation of podocytes in vivo.
Volume: 48
Issue: 7
Pages: 446-51
Publication
First Author: Moeller MJ
Year: 2003
Journal: Genesis
Title: Podocyte-specific expression of cre recombinase in transgenic mice.
Volume: 35
Issue: 1
Pages: 39-42
Publication
First Author: Hsu MF
Year: 2017
Journal: Sci Rep
Title: Protein tyrosine phosphatase Shp2 deficiency in podocytes attenuates lipopolysaccharide-induced proteinuria.
Volume: 7
Issue: 1
Pages: 461
Genotype
Symbol: Ldb1/Ldb1 Tg(NPHS2-cre)295Lbh/?
Background: involves: C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Agrn/Agrn Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Jaml/Jaml Tg(NPHS2-cre)295Lbh/?
Background: B6.Cg-Jaml Tg(NPHS2-cre)295Lbh
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Suleiman H
Year: 2007
Journal: Dev Biol
Title: The podocyte-specific inactivation of Lmx1b, Ldb1 and E2a yields new insight into a transcriptional network in podocytes.
Volume: 304
Issue: 2
Pages: 701-12
Publication
First Author: Riediger F
Year: 2011
Journal: J Am Soc Nephrol
Title: Prorenin receptor is essential for podocyte autophagy and survival.
Volume: 22
Issue: 12
Pages: 2193-202
Allele
Name: transgene insertion, Hiroshi Kawachi
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Dai C
Year: 2010
Journal: Kidney Int
Title: Hepatocyte growth factor signaling ameliorates podocyte injury and proteinuria.
Volume: 77
Issue: 11
Pages: 962-73
Publication
First Author: Verma R
Year: 2015
Journal: Mol Cell Biol
Title: Shp2 Associates with and Enhances Nephrin Tyrosine Phosphorylation and Is Necessary for Foot Process Spreading in Mouse Models of Podocyte Injury.
Volume: 36
Issue: 4
Pages: 596-614
Publication
First Author: Brähler S
Year: 2015
Journal: Am J Physiol Renal Physiol
Title: The NF-κB essential modulator (NEMO) controls podocyte cytoskeletal dynamics independently of NF-κB.
Volume: 309
Issue: 7
Pages: F617-26
Publication
First Author: Brähler S
Year: 2012
Journal: Am J Physiol Renal Physiol
Title: Intrinsic proinflammatory signaling in podocytes contributes to podocyte damage and prolonged proteinuria.
Volume: 303
Issue: 10
Pages: F1473-85
Publication
First Author: Garg P
Year: 2010
Journal: J Biol Chem
Title: Actin-depolymerizing factor cofilin-1 is necessary in maintaining mature podocyte architecture.
Volume: 285
Issue: 29
Pages: 22676-88
Publication
First Author: El-Aouni C
Year: 2006
Journal: J Am Soc Nephrol
Title: Podocyte-specific deletion of integrin-linked kinase results in severe glomerular basement membrane alterations and progressive glomerulosclerosis.
Volume: 17
Issue: 5
Pages: 1334-44
Publication
First Author: Dai C
Year: 2006
Journal: J Am Soc Nephrol
Title: Essential role of integrin-linked kinase in podocyte biology: Bridging the integrin and slit diaphragm signaling.
Volume: 17
Issue: 8
Pages: 2164-75
Genotype
Symbol: Cfl1/Cfl1 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ilk/Ilk Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myo1e/Myo1e Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Atp6ap2/? Tg(NPHS2-cre)295Lbh/?
Background: involves: C57BL/6 * C57BL/6N * SJL
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Schwarz K
Year: 2001
Journal: J Clin Invest
Title: Podocin, a raft-associated component of the glomerular slit diaphragm, interacts with CD2AP and nephrin.
Volume: 108
Issue: 11
Pages: 1621-9
Allele
Name: nephrosis 2, podocin; targeted mutation 1.1, Paul T Brinkkoetter
Allele Type: Targeted
Attribute String: No functional change, Recombinase, Reporter
Publication categories: ProxyCollection
Publication
First Author: Kato H
Year: 2011
Journal: J Biol Chem
Title: Wnt/β-catenin pathway in podocytes integrates cell adhesion, differentiation, and survival.
Volume: 286
Issue: 29
Pages: 26003-15
Genotype
Symbol: Nphs2/Nphs2<+>
Background: involves: C57BL/6NTac
Zygosity: ht
Has Mutant Allele: true
Publication
First Author: Lausecker F
Year: 2018
Journal: Kidney Int
Title: Vinculin is required to maintain glomerular barrier integrity.
Volume: 93
Issue: 3
Pages: 643-655
Publication
First Author: Mao J
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Mammalian target of rapamycin complex 1 activation in podocytes promotes cellular crescent formation.
Volume: 307
Issue: 9
Pages: F1023-32
Publication
First Author: Liu M
Year: 2017
Journal: Nat Commun
Title: Sirt6 deficiency exacerbates podocyte injury and proteinuria through targeting Notch signaling.
Volume: 8
Issue: 1
Pages: 413
Publication
First Author: Ising C
Year: 2016
Journal: Am J Pathol
Title: Prohibitin-2 Depletion Unravels Extra-Mitochondrial Functions at the Kidney Filtration Barrier.
Volume: 186
Issue: 5
Pages: 1128-39
Publication
First Author: George B
Year: 2012
Journal: J Clin Invest
Title: Crk1/2-dependent signaling is necessary for podocyte foot process spreading in mouse models of glomerular disease.
Volume: 122
Issue: 2
Pages: 674-92
Publication
First Author: George B
Year: 2014
Journal: Kidney Int
Title: Crk1/2 and CrkL form a hetero-oligomer and functionally complement each other during podocyte morphogenesis.
Volume: 85
Issue: 6
Pages: 1382-1394
Publication
First Author: Sun Y
Year: 2017
Journal: J Am Soc Nephrol
Title: Kindlin-2 Association with Rho GDP-Dissociation Inhibitor α Suppresses Rac1 Activation and Podocyte Injury.
Volume: 28
Issue: 12
Pages: 3545-3562
Publication
First Author: Hassan H
Year: 2016
Journal: J Am Soc Nephrol
Title: Essential Role of X-Box Binding Protein-1 during Endoplasmic Reticulum Stress in Podocytes.
Volume: 27
Issue: 4
Pages: 1055-65
Publication
First Author: Stotter BR
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Cosmc-dependent mucin-type O-linked glycosylation is essential for podocyte function.
Volume: 318
Issue: 2
Pages: F518-F530
Publication
First Author: Horne SJ
Year: 2018
Journal: Diabetes
Title: Podocyte-Specific Loss of Krüppel-Like Factor 6 Increases Mitochondrial Injury in Diabetic Kidney Disease.
Volume: 67
Issue: 11
Pages: 2420-2433
Publication
First Author: Garsen M
Year: 2016
Journal: J Am Soc Nephrol
Title: Endothelin-1 Induces Proteinuria by Heparanase-Mediated Disruption of the Glomerular Glycocalyx.
Volume: 27
Issue: 12
Pages: 3545-3551
Publication
First Author: Lenoir O
Year: 2014
Journal: J Am Soc Nephrol
Title: Direct action of endothelin-1 on podocytes promotes diabetic glomerulosclerosis.
Volume: 25
Issue: 5
Pages: 1050-62
Publication
First Author: Zhou H
Year: 2017
Journal: Sci Rep
Title: Loss of the podocyte glucocorticoid receptor exacerbates proteinuria after injury.
Volume: 7
Issue: 1
Pages: 9833
Publication
First Author: Papakrivopoulou E
Year: 2018
Journal: J Pathol
Title: Vangl2, a planar cell polarity molecule, is implicated in irreversible and reversible kidney glomerular injury.
Volume: 246
Issue: 4
Pages: 485-496
Allele
Name: transgene insertion 1, Farhad R Danesh
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Hosoe-Nagai Y
Year: 2017
Journal: Lab Invest
Title: Re-expression of Sall1 in podocytes protects against adriamycin-induced nephrosis.
Volume: 97
Issue: 11
Pages: 1306-1320
Publication
First Author: Asao R
Year: 2018
Journal: Sci Rep
Title: Rac1 in podocytes promotes glomerular repair and limits the formation of sclerosis.
Volume: 8
Issue: 1
Pages: 5061
Publication
First Author: Ishizaka M
Year: 2015
Journal: Biochem Biophys Res Commun
Title: Podocyte-specific deletion of Rac1 leads to aggravation of renal injury in STZ-induced diabetic mice.
Volume: 467
Issue: 3
Pages: 549-55
Publication
First Author: Ma H
Year: 2010
Journal: J Am Soc Nephrol
Title: Inhibition of podocyte FAK protects against proteinuria and foot process effacement.
Volume: 21
Issue: 7
Pages: 1145-56
Strain
Attribute String: congenic, mutant strain, targeted mutation, transgenic
Publication
First Author: Zhang L
Year: 2019
Journal: Cell Death Dis
Title: C/EBPα deficiency in podocytes aggravates podocyte senescence and kidney injury in aging mice.
Volume: 10
Issue: 10
Pages: 684
Publication
First Author: Zhang S
Year: 2020
Journal: Am J Transl Res
Title: POFUT1 is dispensable for structure, function and survival of mouse podocytes.
Volume: 12
Issue: 5
Pages: 2212-2224
Publication
First Author: Li G
Year: 2020
Journal: Am J Pathol
Title: Podocytopathy and Nephrotic Syndrome in Mice with Podocyte-Specific Deletion of the Asah1 Gene: Role of Ceramide Accumulation in Glomeruli.
Volume: 190
Issue: 6
Pages: 1211-1223
Publication  
First Author: Zhong F
Year: 2016
Journal: Sci Rep
Title: Role of C/EBP-α in Adriamycin-induced podocyte injury.
Volume: 6
Pages: 33520
Publication
First Author: Zhong F
Year: 2018
Journal: J Am Soc Nephrol
Title: Protein S Protects against Podocyte Injury in Diabetic Nephropathy.
Volume: 29
Issue: 5
Pages: 1397-1410
Publication
First Author: Yamamoto-Nonaka K
Year: 2016
Journal: J Am Soc Nephrol
Title: Cathepsin D in Podocytes Is Important in the Pathogenesis of Proteinuria and CKD.
Volume: 27
Issue: 9
Pages: 2685-700
Publication
First Author: Huber TB
Year: 2009
Journal: J Am Soc Nephrol
Title: Loss of podocyte aPKClambda/iota causes polarity defects and nephrotic syndrome.
Volume: 20
Issue: 4
Pages: 798-806
Publication
First Author: Nagayama Y
Year: 2014
Journal: Am J Physiol Renal Physiol
Title: Gp130-dependent signaling in the podocyte.
Volume: 307
Issue: 3
Pages: F346-55
Publication  
First Author: Lin CL
Year: 2019
Journal: EMBO Mol Med
Title: A KDM6A-KLF10 reinforcing feedback mechanism aggravates diabetic podocyte dysfunction.
Volume: 11
Issue: 5
Publication
First Author: Hayashi K
Year: 2014
Journal: J Clin Invest
Title: KLF4-dependent epigenetic remodeling modulates podocyte phenotypes and attenuates proteinuria.
Volume: 124
Issue: 6
Pages: 2523-37
Publication
First Author: Ren G
Year: 2018
Journal: Am J Physiol Renal Physiol
Title: Podocytes exhibit a specialized protein quality control employing derlin-2 in kidney disease.
Volume: 314
Issue: 3
Pages: F471-F482
Publication
First Author: Johnstone DB
Year: 2011
Journal: Mol Cell Biol
Title: Podocyte-specific deletion of Myh9 encoding nonmuscle myosin heavy chain 2A predisposes mice to glomerulopathy.
Volume: 31
Issue: 10
Pages: 2162-70
Allele
Name: transgene insertion 1, Harry Holthofer
Allele Type: Transgenic
Attribute String: Inducible, Recombinase, Transactivator
Publication categories: ProxyCollection
Genotype
Symbol: Itga3/Itga3 Tg(NPHS2-cre)295Lbh/?
Background: Not Specified
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Lmx1b/Lmx1b Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S7/SvEvBrd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Pdss2/Pdss2 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/Sv * 129X1/SvJ * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Itgb1/Itgb1 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Myh9/Myh9 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129 * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Prkci/Prkci Tg(NPHS2-cre)295Lbh/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Scrib/Scrib Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S1/SvImJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Ano1/Ano1 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129S6/SvEvTac * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fat1/Fat1 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129/Sv * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Fat1/Fat1<+> Tg(NPHS2-cre)295Lbh/?
Background: involves: 129/Sv * 129S4/SvJaeSor * C57BL/6 * C57BL/6J * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Cmas/Cmas Tg(NPHS2-cre)295Lbh/?
Background: involves: 129P2/OlaHsd * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Rhoa/Rhoa Rhpn1/Rhpn1 Tg(NPHS2-cre)295Lbh/?
Background: involves: 129X1/SvJ * C57BL/6 * SJL
Zygosity: cn
Has Mutant Allele: true