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Search results 1 to 100 out of 646 for Npr3

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
4883 | NPR3
Type: gene
Organism: human
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Gene
100495974 | npr3
Type: gene
Organism: frog, western clawed
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Gene
281358 | NPR3
Type: gene
Organism: cattle
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Gene
25339 | Npr3
Type: gene
Organism: rat
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Gene
471581 | NPR3
Type: gene
Organism: chimpanzee
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Gene
612616 | NPR3
Type: gene
Organism: dog, domestic
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Gene
431663 | NPR3
Type: gene
Organism: chicken
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Gene
569395 | npr3
Type: gene
Organism: zebrafish
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Gene
697245 | NPR3
Type: gene
Organism: macaque, rhesus
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Protein Domain
IPR005365 | Npr3
Type: Family
Description: In budding yeasts, Npr3 forms a complex with NPR2. This complex heterodimer is responsible for inactivating TORC1, an evolutionarily conserved protein complex that controls cell size via nutritional input signals, specifically, in response to amino acid starvation []. In fission yeast, Nitrogen permease regulator 3-like protein (part of GATOR complex) is dispensable for TORC1 regulation under amino acid starvation and thus, responds to nitrogen starvation [].In humans, Npr3 like protein, NPRL3, is part of the GATOR1 complex that functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway [].
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Protein Coding Gene
MGI:97373 | Npr3
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
- | J:137503
     
First Author: Harris BS
Year: 2008
Journal: MGI Direct Data Submission
Title: Longjohn 4 Jackson (lgj-4J); a new remutation in the Npr3 gene
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Gene
8131 | NPRL3
Type: gene
Organism: human
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Publication
- | J:132964
     
First Author: Du X
Year: 2008
Journal: MGI Direct Data Submission
Title: Eel, an ENU-induced mutation of Npr3 associated with spinal abnormalities
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Publication
- | J:131428
     
First Author: Karst SY
Year: 2008
Journal: MGI Direct Data Submission
Title: Longjohn 3 Jackson (lgj-3J); a remutation in the Npr3 gene
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Protein
D6RGB2
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
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Protein
A2AAX8
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: true
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Protein
Q8BZ59
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
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Protein
A7M7S2
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: false
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Protein
Q8BXG6
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: false
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Publication
33534698 | -
   
First Author: Fukuda T
Year: 2021
Journal: Elife
Title: Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase.
Volume: 10
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Publication
37528869 | J:350123
First Author: Guarino BD
Year: 2023
Journal: Pulm Circ
Title: Deletion of the Npr3 gene increases severity of acute lung injury in obese mice.
Volume: 13
Issue: 3
Pages: e12270
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Gene
108281130 | LOC108281130
Type: gene
Organism: human
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Protein
Q8VIJ8
Organism: Mus musculus/domesticus
Length: 569  
Fragment?: false
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Publication
19521502 | -
First Author: Neklesa TK
Year: 2009
Journal: PLoS Genet
Title: A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.
Volume: 5
Issue: 6
Pages: e1000515
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Publication
23723238 | -
First Author: Bar-Peled L
Year: 2013
Journal: Science
Title: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Volume: 340
Issue: 6136
Pages: 1100-6
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Publication
29374073 | J:278013
First Author: Tang J
Year: 2018
Journal: Circ Res
Title: Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart.
Volume: 122
Issue: 7
Pages: 984-993
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Gene
453785 | NPRL3
Type: gene
Organism: chimpanzee
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Gene
611588 | NPRL3
Type: gene
Organism: dog, domestic
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Gene
534485 | NPRL3
Type: gene
Organism: cattle
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Gene
722264 | NPRL3
Type: gene
Organism: macaque, rhesus
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Publication
23979929 | J:218364
First Author: Dauphinee SM
Year: 2013
Journal: G3 (Bethesda)
Title: Characterization of two ENU-induced mutations affecting mouse skeletal morphology.
Volume: 3
Issue: 10
Pages: 1753-8
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Publication
10468599 | J:57460
First Author: Jaubert J
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3).
Volume: 96
Issue: 18
Pages: 10278-83
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Publication
27056912 | J:256775
First Author: Zhang H
Year: 2016
Journal: Circ Res
Title: Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.
Volume: 118
Issue: 12
Pages: 1880-93
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Publication
10377427 | J:56058
First Author: Matsukawa N
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.
Volume: 96
Issue: 13
Pages: 7403-8
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Publication
27959934 | J:243806
First Author: Esapa CT
Year: 2016
Journal: PLoS One
Title: Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway.
Volume: 11
Issue: 12
Pages: e0167916
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Publication
29326144 | J:320727
First Author: Miyazaki T
Year: 2018
Journal: Circ Res
Title: A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction.
Volume: 122
Issue: 5
Pages: 742-751
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Publication
39353431 | J:358125
     
First Author: Patiño M
Year: 2024
Journal: Neuron
Title: Transcriptomic cell-type specificity of local cortical circuits.
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Publication
33203221 | J:321041
First Author: Räsänen M
Year: 2021
Journal: Circulation
Title: VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration.
Volume: 143
Issue: 1
Pages: 65-77
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Publication
21915269 | J:177928
First Author: Morton NM
Year: 2011
Journal: PLoS One
Title: A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes.
Volume: 6
Issue: 9
Pages: e23944
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Publication
27740716 | J:346629
First Author: Schmidt H
Year: 2016
Journal: Eur J Neurosci
Title: Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.
Volume: 44
Issue: 12
Pages: 2991-3000
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Publication
34614389 | J:319415
First Author: Kirchgessner MA
Year: 2021
Journal: Curr Biol
Title: Distinct "driving" versus "modulatory" influences of different visual corticothalamic pathways.
Volume: 31
Issue: 23
Pages: 5121-5137.e7
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Publication
34497373 | J:317975
First Author: Lu P
Year: 2021
Journal: Nat Cell Biol
Title: Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling.
Volume: 23
Issue: 9
Pages: 967-977
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Publication
37023750 | J:335167
First Author: Lu P
Year: 2023
Journal: Dev Cell
Title: Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.
Volume: 58
Issue: 9
Pages: 791-805.e4
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Publication
27019112 | J:231966
First Author: Zhang H
Year: 2016
Journal: Nat Genet
Title: Genetic lineage tracing identifies endocardial origin of liver vasculature.
Volume: 48
Issue: 5
Pages: 537-43
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Publication
31943281 | J:309164
First Author: Tian X
Year: 2020
Journal: EMBO J
Title: Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Volume: 39
Issue: 4
Pages: e102675
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Publication
33731450 | J:309679
First Author: Cui Q
Year: 2021
Journal: J Neurosci
Title: Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns.
Volume: 41
Issue: 18
Pages: 4036-4059
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Publication
35482005 | J:331898
 
First Author: Liu K
Year: 2022
Journal: J Cell Biol
Title: Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart.
Volume: 221
Issue: 6
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Publication
28729659 | J:263128
First Author: Tian X
Year: 2017
Journal: Nat Commun
Title: Identification of a hybrid myocardial zone in the mammalian heart after birth.
Volume: 8
Issue: 1
Pages: 87
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Protein Coding Gene
MGP_CAROLIEiJ_G0019675 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021732 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021692 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021699 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021475 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97373 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0022138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020991 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021444 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021546 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021636 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021571 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0022161 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020734 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0021047 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0016055 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020572 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
8620881 | J:32857
First Author: Yanaka N
Year: 1996
Journal: Eur J Biochem
Title: Structure of the 5'-flanking regulatory region of the mouse gene encoding the clearance receptor for atrial natriuretic peptide.
Volume: 237
Issue: 1
Pages: 25-34
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Publication
31255729 | J:279011
 
First Author: Ishikawa K
Year: 2019
Journal: Mol Cell Endocrinol
Title: Natriuretic peptide signaling is involved in the expression of oxidative metabolism-related and muscle fiber constitutive genes in the gastrocnemius muscle.
Volume: 494
Pages: 110493
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Publication
29242602 | J:286937
First Author: Moghtadaei M
Year: 2017
Journal: Sci Rep
Title: Altered heart rate regulation by the autonomic nervous system in mice lacking natriuretic peptide receptor C (NPR-C).
Volume: 7
Issue: 1
Pages: 17564
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Publication
28743802 | J:260206
 
First Author: Wu W
Year: 2017
Journal: Sci Signal
Title: Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance.
Volume: 10
Issue: 489
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Publication
30239604 | J:294453
First Author: Rahmutula D
Year: 2019
Journal: Cardiovasc Res
Title: Absence of natriuretic peptide clearance receptor attenuates TGF-β1-induced selective atrial fibrosis and atrial fibrillation.
Volume: 115
Issue: 2
Pages: 357-372
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Publication
35943160 | J:330036
First Author: Harrington EO
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Natriuretic peptide receptor-C mediates the inhibitory effect of atrial natriuretic peptide on neutrophil recruitment to the lung during acute lung injury.
Volume: 323
Issue: 4
Pages: L438-L449
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Publication
9321481 | J:38398
First Author: Savinova OV
Year: 1997
Journal: Mamm Genome
Title: Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15.
Volume: 8
Issue: 10
Pages: 788
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Publication
22960454 | J:189239
First Author: Azer J
Year: 2012
Journal: J Mol Cell Cardiol
Title: Natriuretic peptides regulate heart rate and sinoatrial node function by activating multiple natriuretic peptide receptors.
Volume: 53
Issue: 5
Pages: 715-24
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Publication
37553374 | J:341863
First Author: Cheng C
Year: 2023
Journal: Signal Transduct Target Ther
Title: NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice.
Volume: 8
Issue: 1
Pages: 290
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Skeletal m.
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Testis
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662868
Age: embryonic day 7.0
Specimen Label: 7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662868
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2662868
Age: embryonic day 15.0
Specimen Label: 15
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2662868
Age: embryonic day 17.0
Specimen Label: 17
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785826
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: -/- DA
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785826
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: WT DA
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860126
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: WT Aorta
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7751356
Assay Type: RT-PCR
Annotation Date: 2024-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3829020
Stage: TS20
Assay Id: MGI:7781849
Age: embryonic day 12.5
Image: S4
Specimen Label: EEM
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7751356
Assay Type: RT-PCR
Annotation Date: 2024-11-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3828920
Stage: TS20
Assay Id: MGI:7781849
Age: embryonic day 12.5
Image: S4
Specimen Label: SOM
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_01
Specimen Label: euxassay_010728_01
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_02
Specimen Label: euxassay_010728_02
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_03
Specimen Label: euxassay_010728_03
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_04
Specimen Label: euxassay_010728_04
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:4358296
Assay Type: RNA in situ
Annotation Date: 2009-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:4358417
Age: embryonic day 17.5
Note: Expression was detected in the dorsal nerve roots and at lower levels in the ventral nerve roots. Expression was not detected along the distal portions of the nerves.
Specimen Label: 3T
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
Probe: MGI:4882766
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4945455
Age: embryonic day 11.5
Image: g00975 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g00975 E11.5
Detected: true
Specimen Num: 1
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