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Search results 1 to 100 out of 631 for Npr3

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: rat
Protein Domain
Type: Family
Description: In budding yeasts, Npr3 forms a complex with NPR2. This complex heterodimer is responsible for inactivating TORC1, an evolutionarily conserved protein complex that controls cell size via nutritional input signals, specifically, in response to amino acid starvation []. In fission yeast, Nitrogen permease regulator 3-like protein (part of GATOR complex) is dispensable for TORC1 regulation under amino acid starvation and thus, responds to nitrogen starvation [].In humans, Npr3 like protein, NPRL3, is part of the GATOR1 complex that functions as an inhibitor of the amino acid-sensing branch of the TORC1 pathway [].
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication      
First Author: Harris BS
Year: 2008
Journal: MGI Direct Data Submission
Title: Longjohn 4 Jackson (lgj-4J); a new remutation in the Npr3 gene
Gene
Type: gene
Organism: human
Publication      
First Author: Du X
Year: 2008
Journal: MGI Direct Data Submission
Title: Eel, an ENU-induced mutation of Npr3 associated with spinal abnormalities
Publication      
First Author: Karst SY
Year: 2008
Journal: MGI Direct Data Submission
Title: Longjohn 3 Jackson (lgj-3J); a remutation in the Npr3 gene
Protein
Organism: Mus musculus/domesticus
Length: 80  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 182  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 491  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 582  
Fragment?: false
Publication    
First Author: Fukuda T
Year: 2021
Journal: Elife
Title: Tripartite suppression of fission yeast TORC1 signaling by the GATOR1-Sea3 complex, the TSC complex, and Gcn2 kinase.
Volume: 10
Gene
Type: gene
Organism: human
Protein
Organism: Mus musculus/domesticus
Length: 569  
Fragment?: false
Publication
First Author: Neklesa TK
Year: 2009
Journal: PLoS Genet
Title: A genome-wide screen for regulators of TORC1 in response to amino acid starvation reveals a conserved Npr2/3 complex.
Volume: 5
Issue: 6
Pages: e1000515
Publication
First Author: Bar-Peled L
Year: 2013
Journal: Science
Title: A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1.
Volume: 340
Issue: 6136
Pages: 1100-6
Publication
First Author: Tang J
Year: 2018
Journal: Circ Res
Title: Genetic Fate Mapping Defines the Vascular Potential of Endocardial Cells in the Adult Heart.
Volume: 122
Issue: 7
Pages: 984-993
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Publication
First Author: Dauphinee SM
Year: 2013
Journal: G3 (Bethesda)
Title: Characterization of two ENU-induced mutations affecting mouse skeletal morphology.
Volume: 3
Issue: 10
Pages: 1753-8
Publication
First Author: Jaubert J
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Three new allelic mouse mutations that cause skeletal overgrowth involve the natriuretic peptide receptor C gene (Npr3).
Volume: 96
Issue: 18
Pages: 10278-83
Publication
First Author: Zhang H
Year: 2016
Journal: Circ Res
Title: Endocardium Minimally Contributes to Coronary Endothelium in the Embryonic Ventricular Free Walls.
Volume: 118
Issue: 12
Pages: 1880-93
Publication
First Author: Matsukawa N
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: The natriuretic peptide clearance receptor locally modulates the physiological effects of the natriuretic peptide system.
Volume: 96
Issue: 13
Pages: 7403-8
Publication
First Author: Esapa CT
Year: 2016
Journal: PLoS One
Title: Mice with an N-Ethyl-N-Nitrosourea (ENU) Induced Tyr209Asn Mutation in Natriuretic Peptide Receptor 3 (NPR3) Provide a Model for Kyphosis Associated with Activation of the MAPK Signaling Pathway.
Volume: 11
Issue: 12
Pages: e0167916
Publication
First Author: Miyazaki T
Year: 2018
Journal: Circ Res
Title: A New Secretory Peptide of Natriuretic Peptide Family, Osteocrin, Suppresses the Progression of Congestive Heart Failure After Myocardial Infarction.
Volume: 122
Issue: 5
Pages: 742-751
Publication
First Author: Schmidt H
Year: 2016
Journal: Eur J Neurosci
Title: Dorsal root ganglion axon bifurcation tolerates increased cyclic GMP levels: the role of phosphodiesterase 2A and scavenger receptor Npr3.
Volume: 44
Issue: 12
Pages: 2991-3000
Publication
First Author: Räsänen M
Year: 2021
Journal: Circulation
Title: VEGF-B Promotes Endocardium-Derived Coronary Vessel Development and Cardiac Regeneration.
Volume: 143
Issue: 1
Pages: 65-77
Publication
First Author: Morton NM
Year: 2011
Journal: PLoS One
Title: A stratified transcriptomics analysis of polygenic fat and lean mouse adipose tissues identifies novel candidate obesity genes.
Volume: 6
Issue: 9
Pages: e23944
Publication
First Author: Kirchgessner MA
Year: 2021
Journal: Curr Biol
Title: Distinct "driving" versus "modulatory" influences of different visual corticothalamic pathways.
Volume: 31
Issue: 23
Pages: 5121-5137.e7
Publication
First Author: Lu P
Year: 2021
Journal: Nat Cell Biol
Title: Perinatal angiogenesis from pre-existing coronary vessels via DLL4-NOTCH1 signalling.
Volume: 23
Issue: 9
Pages: 967-977
Publication
First Author: Zhang H
Year: 2016
Journal: Nat Genet
Title: Genetic lineage tracing identifies endocardial origin of liver vasculature.
Volume: 48
Issue: 5
Pages: 537-43
Publication
First Author: Lu P
Year: 2023
Journal: Dev Cell
Title: Prerequisite endocardial-mesenchymal transition for murine cardiac trabecular angiogenesis.
Volume: 58
Issue: 9
Pages: 791-805.e4
Publication
First Author: Tian X
Year: 2020
Journal: EMBO J
Title: Generation of a self-cleaved inducible Cre recombinase for efficient temporal genetic manipulation.
Volume: 39
Issue: 4
Pages: e102675
Publication
First Author: Cui Q
Year: 2021
Journal: J Neurosci
Title: Dissociable Roles of Pallidal Neuron Subtypes in Regulating Motor Patterns.
Volume: 41
Issue: 18
Pages: 4036-4059
Publication  
First Author: Liu K
Year: 2022
Journal: J Cell Biol
Title: Lineage tracing clarifies the cellular origin of tissue-resident macrophages in the developing heart.
Volume: 221
Issue: 6
Publication
First Author: Tian X
Year: 2017
Journal: Nat Commun
Title: Identification of a hybrid myocardial zone in the mammalian heart after birth.
Volume: 8
Issue: 1
Pages: 87
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Yanaka N
Year: 1996
Journal: Eur J Biochem
Title: Structure of the 5'-flanking regulatory region of the mouse gene encoding the clearance receptor for atrial natriuretic peptide.
Volume: 237
Issue: 1
Pages: 25-34
Publication  
First Author: Wu W
Year: 2017
Journal: Sci Signal
Title: Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance.
Volume: 10
Issue: 489
Publication
First Author: Rahmutula D
Year: 2019
Journal: Cardiovasc Res
Title: Absence of natriuretic peptide clearance receptor attenuates TGF-β1-induced selective atrial fibrosis and atrial fibrillation.
Volume: 115
Issue: 2
Pages: 357-372
Publication  
First Author: Ishikawa K
Year: 2019
Journal: Mol Cell Endocrinol
Title: Natriuretic peptide signaling is involved in the expression of oxidative metabolism-related and muscle fiber constitutive genes in the gastrocnemius muscle.
Volume: 494
Pages: 110493
Publication
First Author: Moghtadaei M
Year: 2017
Journal: Sci Rep
Title: Altered heart rate regulation by the autonomic nervous system in mice lacking natriuretic peptide receptor C (NPR-C).
Volume: 7
Issue: 1
Pages: 17564
Publication
First Author: Harrington EO
Year: 2022
Journal: Am J Physiol Lung Cell Mol Physiol
Title: Natriuretic peptide receptor-C mediates the inhibitory effect of atrial natriuretic peptide on neutrophil recruitment to the lung during acute lung injury.
Volume: 323
Issue: 4
Pages: L438-L449
Publication
First Author: Savinova OV
Year: 1997
Journal: Mamm Genome
Title: Mouse natriuretic peptide receptor 3 gene maps to proximal chromosome 15.
Volume: 8
Issue: 10
Pages: 788
Publication
First Author: Azer J
Year: 2012
Journal: J Mol Cell Cardiol
Title: Natriuretic peptides regulate heart rate and sinoatrial node function by activating multiple natriuretic peptide receptors.
Volume: 53
Issue: 5
Pages: 715-24
Publication
First Author: Cheng C
Year: 2023
Journal: Signal Transduct Target Ther
Title: NPRC deletion mitigated atherosclerosis by inhibiting oxidative stress, inflammation and apoptosis in ApoE knockout mice.
Volume: 8
Issue: 1
Pages: 290
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Heart
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Spleen
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Lung
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Liver
Detected: false
Specimen Num: 5
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3598828
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Skeletal m.
Detected: false
Specimen Num: 6
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Kidney
Detected: false
Specimen Num: 7
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:2662857
Age: postnatal adult
Specimen Label: Testis
Detected: false
Specimen Num: 8
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603910
Stage: TS10
Assay Id: MGI:2662868
Age: embryonic day 7.0
Specimen Label: 7
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603918
Stage: TS18
Assay Id: MGI:2662868
Age: embryonic day 11.0
Specimen Label: 11
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603923
Stage: TS23
Assay Id: MGI:2662868
Age: embryonic day 15.0
Specimen Label: 15
Detected: false
Specimen Num: 3
GXD Expression      
Probe: MGI:1289508
Assay Type: Northern blot
Annotation Date: 2003-06-16
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1603925
Stage: TS25
Assay Id: MGI:2662868
Age: embryonic day 17.0
Specimen Label: 17
Detected: false
Specimen Num: 4
GXD Expression      
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785826
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: -/- DA
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1785826
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: WT DA
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:7541295
Assay Type: RT-PCR
Annotation Date: 2023-10-20
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1860126
Stage: TS26
Assay Id: MGI:7541393
Age: embryonic day 18.5
Specimen Label: WT Aorta
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_01
Specimen Label: euxassay_010728_01
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_02
Specimen Label: euxassay_010728_02
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_03
Specimen Label: euxassay_010728_03
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4425186
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1716123
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826772
Age: embryonic day 14.5
Image: euxassay_010728_04
Specimen Label: euxassay_010728_04
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4358296
Assay Type: RNA in situ
Annotation Date: 2009-09-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666625
Pattern: Regionally restricted
Stage: TS25
Assay Id: MGI:4358417
Age: embryonic day 17.5
Note: Expression was detected in the dorsal nerve roots and at lower levels in the ventral nerve roots. Expression was not detected along the distal portions of the nerves.
Specimen Label: 3T
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:4882766
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1691619
Pattern: Regionally restricted
Stage: TS19
Assay Id: MGI:4945455
Age: embryonic day 11.5
Image: g00975 E11.5
Note: Expression was region specific and scattered.
Specimen Label: g00975 E11.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4882766
Assay Type: RNA in situ
Annotation Date: 2011-04-11
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1691623
Pattern: Widespread
Stage: TS23
Assay Id: MGI:4945455
Age: embryonic day 15.5
Image: g00975 E15.5
Specimen Label: g00975 E15.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:5508505
Assay Type: RNA in situ
Annotation Date: 2014-02-07
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:2813023
Stage: TS23
Assay Id: MGI:5543216
Age: embryonic day 15.5
Image: GUDMAP:20569
Specimen Label: GUDMAP:20569
Detected: false
Specimen Num: 1
GXD Expression    
Assay Type: In situ reporter (knock in)
Annotation Date: 2021-04-16
Strength: Present
Sex: Female
Emaps: EMAPS:1876728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6693162
Age: postnatal adult
Image: UC Davis_1885055
Specimen Label: UC Davis_1885055
Detected: true
Specimen Num: 9
GXD Expression    
Probe: MGI:6723806
Assay Type: RNA in situ
Annotation Date: 2021-07-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1733719
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:6724005
Age: embryonic day 11.5
Specimen Label: 3B - E11.5 WM
Detected: true
Specimen Num: 3