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Search results 1 to 100 out of 155 for Nps

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0.045s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Han RW
Year: 2009
Journal: Neurosci Lett
Title: Neuropeptide S facilitates spatial memory and mitigates spatial memory impairment induced by N-methyl-D-aspartate receptor antagonist in mice.
Volume: 455
Issue: 1
Pages: 74-7
Publication
First Author: Meis S
Year: 2011
Journal: PLoS One
Title: Neuropeptide S-mediated facilitation of synaptic transmission enforces subthreshold theta oscillations within the lateral amygdala.
Volume: 6
Issue: 3
Pages: e18020
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Jüngling K
Year: 2012
Journal: J Physiol
Title: Activation of neuropeptide S-expressing neurons in the locus coeruleus by corticotropin-releasing factor.
Volume: 590
Issue: 16
Pages: 3701-17
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
Publication
First Author: Gaudet P
Year: 2011
Journal: Brief Bioinform
Title: Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium.
Volume: 12
Issue: 5
Pages: 449-62
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication
First Author: Hannan FM
Year: 2015
Journal: Endocrinology
Title: The Calcilytic Agent NPS 2143 Rectifies Hypocalcemia in a Mouse Model With an Activating Calcium-Sensing Receptor (CaSR) Mutation: Relevance to Autosomal Dominant Hypocalcemia Type 1 (ADH1).
Volume: 156
Issue: 9
Pages: 3114-21
Publication
First Author: Takei Y
Year: 1991
Journal: FEBS Lett
Title: A novel natriuretic peptide isolated from eel cardiac ventricles.
Volume: 282
Issue: 2
Pages: 317-20
Publication
First Author: Schweitz H
Year: 1992
Journal: J Biol Chem
Title: A new member of the natriuretic peptide family is present in the venom of the green mamba (Dendroaspis angusticeps).
Volume: 267
Issue: 20
Pages: 13928-32
Protein Domain
Type: Family
Description: Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) [].
Protein Domain
Type: Family
Description: Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and green mamba natriuretic peptide (DNP) [].
Protein Domain
Type: Family
Description: Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) []C-type natriuretic peptide has vasorelaxant and cGMP-stimulating activities.
Protein
Organism: Mus musculus
Length: 89  
Fragment?: false
Protein
Organism: Mus musculus
Length: 72  
Fragment?: false
Protein
Organism: Mus musculus
Length: 126  
Fragment?: false
Protein Domain
Type: Family
Description: Neuropeptide S (NPS) is a bioactive peptide that may be involved in several biological processes, including food intake, locomotion, wakefulness, arousal, and anxiety. NPS activates its cognate G protein-coupled receptor (NPSR1) at low nanomolar agonist concentrations and induces elevation of intracellular Ca2+ and cAMP [, , ].
Protein
Organism: Mus musculus
Length: 152  
Fragment?: false
Protein
Organism: Mus musculus
Length: 126  
Fragment?: false
Protein
Organism: Mus musculus
Length: 121  
Fragment?: false
Protein
Organism: Mus musculus
Length: 126  
Fragment?: false
Protein
Organism: Mus musculus
Length: 121  
Fragment?: false
Protein
Organism: Mus musculus
Length: 121  
Fragment?: false
Protein
Organism: Mus musculus
Length: 121  
Fragment?: false
Publication  
First Author: Rosenzweig A
Year: 1991
Journal: Annu Rev Biochem
Title: Atrial natriuretic factor and related peptide hormones.
Volume: 60
Pages: 229-55
Publication
First Author: Inagami T
Year: 1989
Journal: J Biol Chem
Title: Atrial natriuretic factor.
Volume: 264
Issue: 6
Pages: 3043-6
Protein
Organism: Mus musculus
Length: 88  
Fragment?: false
Protein
Organism: Mus musculus
Length: 35  
Fragment?: true
Protein Domain
Type: Family
Description: Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins. The familyof NPs includes structurally-related peptides that elicit similar pharmacological spectra. Amongst these arebrain natriuretic peptide (BNP); C-type natriuretic peptide (CNP); ventricular natriuretic peptide (VNP)[]; and Dendroaspis angusticeps (Eastern green mamba) natriuretic peptide (DNP) []Atrial natriuretic factor (ANF) is a potent vasoactive substance synthesized in mammalian atria and is thought to play a key role in cardiovascular homeostasis. It has a cGMP-stimulating activity.
Publication
First Author: Xu YL
Year: 2004
Journal: Neuron
Title: Neuropeptide S: a neuropeptide promoting arousal and anxiolytic-like effects.
Volume: 43
Issue: 4
Pages: 487-97
Publication
First Author: Okamura N
Year: 2007
Journal: Stress
Title: Neuropeptide S: a novel modulator of stress and arousal.
Volume: 10
Issue: 3
Pages: 221-6
Publication
First Author: Beck B
Year: 2005
Journal: Biochem Biophys Res Commun
Title: Peptide S is a novel potent inhibitor of voluntary and fast-induced food intake in rats.
Volume: 332
Issue: 3
Pages: 859-65
Publication
First Author: Reinscheid RK
Year: 2005
Journal: FEBS J
Title: Neuropeptide S as a novel arousal promoting peptide transmitter.
Volume: 272
Issue: 22
Pages: 5689-93
Publication
First Author: Laitinen T
Year: 2004
Journal: Science
Title: Characterization of a common susceptibility locus for asthma-related traits.
Volume: 304
Issue: 5668
Pages: 300-4
Publication
First Author: Meis S
Year: 2008
Journal: PLoS One
Title: Identification of a neuropeptide S responsive circuitry shaping amygdala activity via the endopiriform nucleus.
Volume: 3
Issue: 7
Pages: e2695
Publication
First Author: Xu YL
Year: 2007
Journal: J Comp Neurol
Title: Distribution of neuropeptide S receptor mRNA and neurochemical characteristics of neuropeptide S-expressing neurons in the rat brain.
Volume: 500
Issue: 1
Pages: 84-102
Publication
First Author: Jüngling K
Year: 2008
Journal: Neuron
Title: Neuropeptide S-mediated control of fear expression and extinction: role of intercalated GABAergic neurons in the amygdala.
Volume: 59
Issue: 2
Pages: 298-310
Publication
First Author: Leonard SK
Year: 2008
Journal: Psychopharmacology (Berl)
Title: Pharmacology of neuropeptide S in mice: therapeutic relevance to anxiety disorders.
Volume: 197
Issue: 4
Pages: 601-11
Publication
First Author: Rizzi A
Year: 2008
Journal: Br J Pharmacol
Title: Neuropeptide S is a stimulatory anxiolytic agent: a behavioural study in mice.
Volume: 154
Issue: 2
Pages: 471-9
Publication
First Author: Smith KL
Year: 2006
Journal: Endocrinology
Title: Neuropeptide S stimulates the hypothalamo-pituitary-adrenal axis and inhibits food intake.
Volume: 147
Issue: 7
Pages: 3510-8
Publication
First Author: Vendelin J
Year: 2005
Journal: Am J Respir Cell Mol Biol
Title: Characterization of GPRA, a novel G protein-coupled receptor related to asthma.
Volume: 33
Issue: 3
Pages: 262-70
Publication
First Author: Reinscheid RK
Year: 2005
Journal: Neuroscientist
Title: Neuropeptide S and its receptor: a newly deorphanized G protein-coupled receptor system.
Volume: 11
Issue: 6
Pages: 532-8
Publication  
First Author: Reinscheid RK
Year: 2008
Journal: Results Probl Cell Differ
Title: Neuropeptide S: anatomy, pharmacology, genetics and physiological functions.
Volume: 46
Pages: 145-58
Publication
First Author: D'Amato M
Year: 2007
Journal: Gastroenterology
Title: Neuropeptide s receptor 1 gene polymorphism is associated with susceptibility to inflammatory bowel disease.
Volume: 133
Issue: 3
Pages: 808-17
Protein Domain
Type: Family
Description: This entry represents the neuropeptide S receptor (NPSR), which is a member of the rhodopsin G protein-coupled receptor family []and it binds NPS [, , ]. Like the tissue distribution of NPS, the neuropeptide S receptor is widely distributed in the brain, with high expression levels in cortex, hypothalamus, amygdala and multiple midline thalamic nuclei. Many of these areas have been functionally associated processing of emotional behaviour, promoting arousal and anxiolytic-like effects [, ]. In addition to this, activation of NPSR in the airway epithelium has a number of effects including up-regulation of matrix metalloproteinases which are involved in the pathogenesis of asthma []. It is also thought to be involved in irritable bowel syndrome [].Neuropeptide S (NPS) is a neuropeptide found in human and mammalian brain and is mainly produced by neurons in the amygdala, expression has also been found in other areas of the brain such as the lateral parabrachial nucleus and hypothalamus [, , , ]. Overall, the expression of NPS is restricted in the brain, but it has been found in peripheral sites that include mostly endocrine tissues such as thyroid, mammary gland, salivary gland and testis. Neuropeptide S has been was found to suppress anxiety [, , , ]and appetite [, ], induce wakefulness and hyperactivity, including hyper-sexuality [, , ], and plays a significant role in the extinction of conditioned fear. Central administration of NPS was also found to modulate hypothalamic-pituitary-adrenal axis activity [].
Protein Domain
Type: Conserved_site
Description: Atrial natriuretic peptides (ANPs) are vertebrate hormones that play an important role in the control ofcardiovascular homeostatis, and sodium and water balance in general [, ].There are different NPs that vary in length but share a common core. All are processed from a single precursor.A disulphide bond resident in the C-terminal section is required for full activity of atriopeptins.This entry represent a conserved site which includes the two cysteines involved in the disulfide bond, and two conserved glycines that may be important for the conformation of the peptides.
Publication
First Author: Chen H
Year: 1998
Journal: Nat Genet
Title: Limb and kidney defects in Lmx1b mutant mice suggest an involvement of LMX1B in human nail patella syndrome.
Volume: 19
Issue: 1
Pages: 51-5
Publication
First Author: Huillard E
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Cooperative interactions of BRAFV600E kinase and CDKN2A locus deficiency in pediatric malignant astrocytoma as a basis for rational therapy.
Volume: 109
Issue: 22
Pages: 8710-5
Publication
First Author: Mattheisen GB
Year: 2018
Journal: Cell Rep
Title: Strong G-Protein-Mediated Inhibition of Sodium Channels.
Volume: 23
Issue: 9
Pages: 2770-2781
Publication
First Author: Liu J
Year: 2017
Journal: Cell Stem Cell
Title: The Primate-Specific Gene TMEM14B Marks Outer Radial Glia Cells and Promotes Cortical Expansion and Folding.
Volume: 21
Issue: 5
Pages: 635-649.e8
Publication  
First Author: Wu W
Year: 2017
Journal: Sci Signal
Title: Enhancing natriuretic peptide signaling in adipose tissue, but not in muscle, protects against diet-induced obesity and insulin resistance.
Volume: 10
Issue: 489
Publication
First Author: Han Z
Year: 2012
Journal: J Clin Invest
Title: DNA nanoparticle-mediated ABCA4 delivery rescues Stargardt dystrophy in mice.
Volume: 122
Issue: 9
Pages: 3221-6
Publication
First Author: Cho RW
Year: 2008
Journal: Neuron
Title: mGluR1/5-dependent long-term depression requires the regulated ectodomain cleavage of neuronal pentraxin NPR by TACE.
Volume: 57
Issue: 6
Pages: 858-71
Publication
First Author: Yeste A
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Nanoparticle-mediated codelivery of myelin antigen and a tolerogenic small molecule suppresses experimental autoimmune encephalomyelitis.
Volume: 109
Issue: 28
Pages: 11270-5
Publication  
First Author: Zhang H
Year: 2018
Journal: Front Mol Neurosci
Title: Cohesive Regulation of Neural Progenitor Development by microRNA miR-26, Its Host Gene Ctdsp and Target Gene Emx2 in the Mouse Embryonic Cerebral Cortex.
Volume: 11
Pages: 44
Publication
First Author: Gao C
Year: 2020
Journal: Nat Commun
Title: Treatment of atherosclerosis by macrophage-biomimetic nanoparticles via targeted pharmacotherapy and sequestration of proinflammatory cytokines.
Volume: 11
Issue: 1
Pages: 2622
Publication  
First Author: Tao W
Year: 2020
Journal: Sci Transl Med
Title: siRNA nanoparticles targeting CaMKIIγ in lesional macrophages improve atherosclerotic plaque stability in mice.
Volume: 12
Issue: 553
Publication
First Author: Leoni G
Year: 2015
Journal: J Clin Invest
Title: Annexin A1-containing extracellular vesicles and polymeric nanoparticles promote epithelial wound repair.
Volume: 125
Issue: 3
Pages: 1215-27
Publication
First Author: Pi M
Year: 2005
Journal: J Biol Chem
Title: Identification of a novel extracellular cation-sensing G-protein-coupled receptor.
Volume: 280
Issue: 48
Pages: 40201-9
Publication
First Author: Sangaralingham SJ
Year: 2007
Journal: J Endocrinol
Title: Estrogen protects against the development of salt-induced cardiac hypertrophy in heterozygous proANP gene-disrupted mice.
Volume: 194
Issue: 1
Pages: 143-52
Publication  
First Author: Ordikhani F
Year: 2018
Journal: JCI Insight
Title: Targeting antigen-presenting cells by anti-PD-1 nanoparticles augments antitumor immunity.
Volume: 3
Issue: 20
Publication
First Author: Feng J
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Calcium-sensing receptor is a physiologic multimodal chemosensor regulating gastric G-cell growth and gastrin secretion.
Volume: 107
Issue: 41
Pages: 17791-6
Publication
First Author: Walther T
Year: 2003
Journal: Regul Pept
Title: Fibrosis rather than blood pressure determines cardiac BNP expression in mice.
Volume: 116
Issue: 1-3
Pages: 95-100
Publication
First Author: Yen CL
Year: 2019
Journal: J Immunol
Title: Targeted Delivery of Curcumin Rescues Endoplasmic Reticulum-Retained Mutant NOX2 Protein and Avoids Leukocyte Apoptosis.
Volume: 202
Issue: 12
Pages: 3394-3403
Publication
First Author: Bonegio RG
Year: 2011
Journal: Kidney Int
Title: The fate of Notch-deficient nephrogenic progenitor cells during metanephric kidney development.
Volume: 79
Issue: 10
Pages: 1099-112
Publication
First Author: Kilić A
Year: 2007
Journal: Endocrinology
Title: Local actions of atrial natriuretic peptide counteract angiotensin II stimulated cardiac remodeling.
Volume: 148
Issue: 9
Pages: 4162-9
Publication
First Author: Aggarwal A
Year: 2015
Journal: Biochim Biophys Acta
Title: The calcium-sensing receptor: A promising target for prevention of colorectal cancer.
Volume: 1853
Issue: 9
Pages: 2158-67
Publication
First Author: Salvalaio M
Year: 2016
Journal: PLoS One
Title: Targeted Polymeric Nanoparticles for Brain Delivery of High Molecular Weight Molecules in Lysosomal Storage Disorders.
Volume: 11
Issue: 5
Pages: e0156452
Publication
First Author: Mori N
Year: 2000
Journal: Am J Physiol Gastrointest Liver Physiol
Title: Hepatic microvascular responses to ischemia-reperfusion in low-density lipoprotein receptor knockout mice.
Volume: 279
Issue: 6
Pages: G1257-64