Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5811017 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640619 |
|
Stage: |
TS19 |
Assay Id: |
MGI:5823674 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Supplemental Data - Npvf |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5811017 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603919 |
|
Stage: |
TS19 |
Assay Id: |
MGI:5823674 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Supplemental Data - Npvf |
Detected: |
false |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5811017 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1640617 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5823674 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
Supplemental Table 1 - Npvf |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5811017 |
Assay Type: |
RNA in situ |
Annotation Date: |
2017-02-09 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5823674 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
Supplemental Table 1 - Npvf |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ubuka T |
Year: |
2023 |
Journal: |
Cell Tissue Res |
Title: |
A mammalian gonadotropin-inhibitory hormone homolog RFamide-related peptide 3 regulates pain and anxiety in mice. |
Volume: |
391 |
Issue: |
1 |
Pages: |
159-172 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu Q |
Year: |
2001 |
Journal: |
J Biol Chem |
Title: |
Identification and characterization of novel mammalian neuropeptide FF-like peptides that attenuate morphine-induced antinociception. |
Volume: |
276 |
Issue: |
40 |
Pages: |
36961-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mamgain A |
Year: |
2021 |
Journal: |
J Neurosci |
Title: |
RFamide-Related Peptide Neurons Modulate Reproductive Function and Stress Responses. |
Volume: |
41 |
Issue: |
3 |
Pages: |
474-488 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Hinuma S |
Year: |
2000 |
Journal: |
Nat Cell Biol |
Title: |
New neuropeptides containing carboxy-terminal RFamide and their receptor in mammals. |
Volume: |
2 |
Issue: |
10 |
Pages: |
703-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Constantin S |
Year: |
2021 |
Journal: |
Endocrinology |
Title: |
An Inhibitory Circuit From Brainstem to GnRH Neurons in Male Mice: A New Role for the RFRP Receptor. |
Volume: |
162 |
Issue: |
5 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kiyohara M |
Year: |
2017 |
Journal: |
Sci Rep |
Title: |
Involvement of gonadotropin-inhibitory hormone in pubertal disorders induced by thyroid status. |
Volume: |
7 |
Issue: |
1 |
Pages: |
1042 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2011-02-07 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:3529728 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:4882082 |
Age: |
postnatal day 55 |
Image: |
S3 |
|
Specimen Label: |
S3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753623 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
Image: |
S3 |
Note: |
Expression is present in the neurons of the dorsomedial hypothalamic nucleus. |
Specimen Label: |
S3 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753623 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Rfrp |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Moderate |
Sex: |
Not Specified |
Emaps: |
EMAPS:1754423 |
Pattern: |
Not Specified |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
Table S5 - Rfrp |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753723 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009659_11 |
|
Specimen Label: |
euxassay_009659_11 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753723 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009659_14 |
|
Specimen Label: |
euxassay_009659_14 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:4423930 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1753723 |
Pattern: |
Single cells |
Stage: |
TS23 |
Assay Id: |
MGI:4826774 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_009659_15 |
|
Specimen Label: |
euxassay_009659_15 |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689419 |
|
Stage: |
TS19 |
Assay Id: |
MGI:6191203 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
Table S2 - E11.5 - Rfrp |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689421 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:6191203 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
Table S2 - E13.5 - Rfrp |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689424 |
Pattern: |
Not Specified |
Stage: |
TS24 |
Assay Id: |
MGI:6191203 |
Age: |
embryonic day 15.5 |
|
|
Specimen Label: |
Table S2 - E15.5 - Rfrp |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689426 |
Pattern: |
Not Specified |
Stage: |
TS26 |
Assay Id: |
MGI:6191203 |
Age: |
embryonic day 18.5 |
|
|
Specimen Label: |
Table S2 - E18.5 - Rfrp |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191203 |
Age: |
postnatal day 4 |
|
|
Specimen Label: |
Table S2 - P4 - Rfrp |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191203 |
Age: |
postnatal day 14 |
|
|
Specimen Label: |
Table S2 - P14 - Rfrp |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6179239 |
Assay Type: |
RNA in situ |
Annotation Date: |
2018-07-25 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1689428 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6191203 |
Age: |
postnatal day 28 |
|
|
Specimen Label: |
Table S2 - P28 - Rfrp |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
Publication |
First Author: |
León S |
Year: |
2014 |
Journal: |
Endocrinology |
Title: |
Physiological roles of gonadotropin-inhibitory hormone signaling in the control of mammalian reproductive axis: studies in the NPFF1 receptor null mouse. |
Volume: |
155 |
Issue: |
8 |
Pages: |
2953-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Poling MC |
Year: |
2012 |
Journal: |
Endocrinology |
Title: |
Development, sex steroid regulation, and phenotypic characterization of RFamide-related peptide (Rfrp) gene expression and RFamide receptors in the mouse hypothalamus. |
Volume: |
153 |
Issue: |
4 |
Pages: |
1827-40 |
|
•
•
•
•
•
|
Publication |
First Author: |
Quignon C |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
Thyroid hormone receptors are required for the melatonin-dependent control of Rfrp gene expression in mice. |
Volume: |
34 |
Issue: |
9 |
Pages: |
12072-12082 |
|
•
•
•
•
•
|
UniProt Feature |
Begin: |
108 |
Description: |
Neuropeptide NPVF |
Type: |
peptide |
End: |
125 |
|
•
•
•
•
•
|
Component |
|
•
•
•
•
•
|
Publication |
First Author: |
Whittaker DE |
Year: |
2021 |
Journal: |
J Clin Invest |
Title: |
A recessive PRDM13 mutation results in congenital hypogonadotropic hypogonadism and cerebellar hypoplasia. |
Volume: |
131 |
Issue: |
24 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lewandowski JP |
Year: |
2015 |
Journal: |
Dev Biol |
Title: |
Spatiotemporal regulation of GLI target genes in the mammalian limb bud. |
Volume: |
406 |
Issue: |
1 |
Pages: |
92-103 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Thompson CL |
Year: |
2014 |
Journal: |
Neuron |
Title: |
A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain. |
Volume: |
83 |
Issue: |
2 |
Pages: |
309-323 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Magdaleno S |
Year: |
2006 |
Journal: |
PLoS Biol |
Title: |
BGEM: an in situ hybridization database of gene expression in the embryonic and adult mouse nervous system. |
Volume: |
4 |
Issue: |
4 |
Pages: |
e86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
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Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
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Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
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Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
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Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
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Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
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Allele |
Name: |
neuropeptide VF precursor; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
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Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
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Allele |
Name: |
neuropeptide VF precursor; targeted mutation 1.1, Takayoshi Ubuka |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
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Allele |
Name: |
neuropeptide VF precursor; targeted mutation 1.1, Greg M Anderson |
Allele Type: |
Targeted |
Attribute String: |
Recombinase |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
188
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Fragment?: |
false |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
188
 |
Fragment?: |
false |
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Publication |
First Author: |
Smith JT |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Variation in kisspeptin and RFamide-related peptide (RFRP) expression and terminal connections to gonadotropin-releasing hormone neurons in the brain: a novel medium for seasonal breeding in the sheep. |
Volume: |
149 |
Issue: |
11 |
Pages: |
5770-82 |
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Publication |
First Author: |
Clarke IJ |
Year: |
2008 |
Journal: |
Endocrinology |
Title: |
Potent action of RFamide-related peptide-3 on pituitary gonadotropes indicative of a hypophysiotropic role in the negative regulation of gonadotropin secretion. |
Volume: |
149 |
Issue: |
11 |
Pages: |
5811-21 |
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Publication |
First Author: |
Kimmel CB |
Year: |
1998 |
Journal: |
Dev Biol |
Title: |
The shaping of pharyngeal cartilages during early development of the zebrafish. |
Volume: |
203 |
Issue: |
2 |
Pages: |
245-63 |
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Publication |
First Author: |
Koda A |
Year: |
2002 |
Journal: |
Endocrinology |
Title: |
A novel amphibian hypothalamic neuropeptide: isolation, localization, and biological activity. |
Volume: |
143 |
Issue: |
2 |
Pages: |
411-9 |
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Publication |
First Author: |
Rőszer T |
Year: |
2012 |
Journal: |
Peptides |
Title: |
FMRFamide-related peptides: anti-opiate transmitters acting in apoptosis. |
Volume: |
34 |
Issue: |
1 |
Pages: |
177-85 |
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Protein Domain |
Type: |
Family |
Description: |
This family includes both FMRFamide-related peptides andgrowth hormone-releasing peptides.FMRFamide-related peptides are neurotransmitters, hormone-like substances and tumor suppressor peptides []. Neuropeptide RFRP-1 acts as a potent negative regulator of gonadotropin synthesis and secretion. Neuropeptides NPSF and NPVF efficiently inhibit forskolin-induced production of cAMP, but RFRP-2 shows no inhibitory activity. Neuropeptide NPVF blocks morphine-induced analgesia. FMRFamide-related peptides may act in concert with kisspeptin, through opposing affects, to regulate the activity of gonadotropin-releasing hormone (GnRH) neurons across the seasons, leading to an annual change in fertility and the cyclical seasonal transition from non-breeding to breeding season [, , ]. The primary role of growth hormone-releasing peptide (fGRP) is to release GH from the pituitary []. |
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Strain |
Attribute String: |
mutant strain, targeted mutation |
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Genotype |
Symbol: |
Npvf/Npvf Tg(Nes-cre)1Nogu/? |
Background: |
involves: C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Genotype |
Symbol: |
Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Npvf/Npvf<+> |
Background: |
involves: 129S1/Sv * 129X1/SvJ * C57BL/6 |
Zygosity: |
cn |
Has Mutant Allele: |
true |
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Publication |
First Author: |
Jaroslawska J |
Year: |
2015 |
Journal: |
PLoS Genet |
Title: |
Npvf: Hypothalamic Biomarker of Ambient Temperature Independent of Nutritional Status. |
Volume: |
11 |
Issue: |
6 |
Pages: |
e1005287 |
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