Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Iskander K |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
NQO1 and NQO2 regulation of humoral immunity and autoimmunity. |
Volume: |
281 |
Issue: |
41 |
Pages: |
30917-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iskander K |
Year: |
2004 |
Journal: |
Cancer Res |
Title: |
Deficiency of NRH:quinone oxidoreductase 2 increases susceptibility to 7,12-dimethylbenz(a)anthracene and benzo(a)pyrene-induced skin carcinogenesis. |
Volume: |
64 |
Issue: |
17 |
Pages: |
5925-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Iskander K |
Year: |
2005 |
Journal: |
Chem Biol Interact |
Title: |
Quinone oxidoreductases in protection against myelogenous hyperplasia and benzene toxicity. |
Volume: |
153-154 |
|
Pages: |
147-57 |
|
•
•
•
•
•
|
Publication |
First Author: |
Long DJ 2nd |
Year: |
2002 |
Journal: |
J Biol Chem |
Title: |
Disruption of dihydronicotinamide riboside:quinone oxidoreductase 2 (NQO2) leads to myeloid hyperplasia of bone marrow and decreased sensitivity to menadione toxicity. |
Volume: |
277 |
Issue: |
48 |
Pages: |
46131-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Das A |
Year: |
2006 |
Journal: |
Free Radic Biol Med |
Title: |
BALT development and augmentation of hyperoxic lung injury in mice deficient in NQO1 and NQO2. |
Volume: |
40 |
Issue: |
10 |
Pages: |
1843-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mailliet F |
Year: |
2004 |
Journal: |
FEBS Lett |
Title: |
Organs from mice deleted for NRH:quinone oxidoreductase 2 are deprived of the melatonin binding site MT3. |
Volume: |
578 |
Issue: |
1-2 |
Pages: |
116-20 |
|
•
•
•
•
•
|
Publication |
First Author: |
Janda E |
Year: |
2023 |
Journal: |
Sci Rep |
Title: |
Autophagy and neuroprotection in astrocytes exposed to 6-hydroxydopamine is negatively regulated by NQO2: relevance to Parkinson's disease. |
Volume: |
13 |
Issue: |
1 |
Pages: |
21624 |
|
•
•
•
•
•
|
Publication |
First Author: |
Celli CM |
Year: |
2006 |
Journal: |
Biochem Pharmacol |
Title: |
NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs. |
Volume: |
72 |
Issue: |
3 |
Pages: |
366-76 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adikesavan AK |
Year: |
2007 |
Journal: |
Cancer Res |
Title: |
In vivo role of NAD(P)H:quinone oxidoreductase 1 in metabolic activation of mitomycin C and bone marrow cytotoxicity. |
Volume: |
67 |
Issue: |
17 |
Pages: |
7966-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Patrick BA |
Year: |
2011 |
Journal: |
Oncogene |
Title: |
Disruption of NAD(P)H:quinone oxidoreductase 1 gene in mice leads to 20S proteasomal degradation of p63 resulting in thinning of epithelium and chemical-induced skin cancer. |
Volume: |
30 |
Issue: |
9 |
Pages: |
1098-107 |
|
•
•
•
•
•
|
Publication |
First Author: |
Long DJ 2nd |
Year: |
2000 |
Journal: |
Gene |
Title: |
Mouse NRH:quinone oxidoreductase (NQO2): cloning of cDNA and gene- and tissue-specific expression. |
Volume: |
252 |
Issue: |
1-2 |
Pages: |
107-17 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
Benoit CE |
Year: |
2010 |
Journal: |
J Neurosci |
Title: |
Loss of quinone reductase 2 function selectively facilitates learning behaviors. |
Volume: |
30 |
Issue: |
38 |
Pages: |
12690-700 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cassagnes LE |
Year: |
2018 |
Journal: |
Free Radic Biol Med |
Title: |
Oxidative stress and neurodegeneration: The possible contribution of quinone reductase 2. |
Volume: |
120 |
|
Pages: |
56-61 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:650714 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1751423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826778 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_006873_12 |
|
Specimen Label: |
euxassay_006873_12 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:650714 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1751423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826778 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_006873_13 |
|
Specimen Label: |
euxassay_006873_13 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:650714 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1751423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826778 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_006873_14 |
|
Specimen Label: |
euxassay_006873_14 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:650714 |
Assay Type: |
RNA in situ |
Annotation Date: |
2010-09-14 |
Strength: |
Strong |
Sex: |
Not Specified |
Emaps: |
EMAPS:1751423 |
Pattern: |
Regionally restricted |
Stage: |
TS23 |
Assay Id: |
MGI:4826778 |
Age: |
embryonic day 14.5 |
Image: |
euxassay_006873_15 |
|
Specimen Label: |
euxassay_006873_15 |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kumaki K |
Year: |
1977 |
Journal: |
J Biol Chem |
Title: |
Genetic differences in induction of cytosol reduced-NAD(P):menadione oxidoreductase and microsomal aryl hydrocarbon hydroxylase in the mouse. |
Volume: |
252 |
Issue: |
1 |
Pages: |
157-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gould NL |
Year: |
2020 |
Journal: |
J Neurosci |
Title: |
Dopamine-Dependent QR2 Pathway Activation in CA1 Interneurons Enhances Novel Memory Formation. |
Volume: |
40 |
Issue: |
45 |
Pages: |
8698-8714 |
|
•
•
•
•
•
|
Publication |
First Author: |
Petersen DD |
Year: |
1989 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Marked increases in hepatic NAD(P)H:oxidoreductase gene transcription and mRNA levels correlated with a mouse chromosome 7 deletion. |
Volume: |
86 |
Issue: |
17 |
Pages: |
6699-703 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kaiserman D |
Year: |
2002 |
Journal: |
Genomics |
Title: |
Comparison of human chromosome 6p25 with mouse chromosome 13 reveals a greatly expanded ov-serpin gene repertoire in the mouse. |
Volume: |
79 |
Issue: |
3 |
Pages: |
349-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mammalian Functional Genomics Centre |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
|
Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GO Central curators, GOA curators, Rhea curators |
Year: |
2020 |
|
Title: |
Automatic Gene Ontology annotation based on Rhea mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators, MGI curators |
Year: |
2001 |
|
Title: |
Gene Ontology annotation based on Enzyme Commission mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kawai J |
Year: |
2001 |
Journal: |
Nature |
Title: |
Functional annotation of a full-length mouse cDNA collection. |
Volume: |
409 |
Issue: |
6821 |
Pages: |
685-90 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okazaki Y |
Year: |
2002 |
Journal: |
Nature |
Title: |
Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. |
Volume: |
420 |
Issue: |
6915 |
Pages: |
563-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Chen D |
Year: |
2017 |
Journal: |
Biol Reprod |
Title: |
NQO2 inhibition relieves reactive oxygen species effects on mouse oocyte meiotic maturation and embryo development. |
Volume: |
97 |
Issue: |
4 |
Pages: |
598-611 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shen J |
Year: |
2010 |
Journal: |
Cancer Res |
Title: |
Inactivation of the quinone oxidoreductases NQO1 and NQO2 strongly elevates the incidence and multiplicity of chemically induced skin tumors. |
Volume: |
70 |
Issue: |
3 |
Pages: |
1006-14 |
|
•
•
•
•
•
|
Allele |
Name: |
N-ribosyldihydronicotinamide quinone reductase 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center |
Allele Type: |
Endonuclease-mediated |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
coisogenic, endonuclease-mediated mutation, mutant strain |
|
•
•
•
•
•
|
GO Term |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
This entry represents a group of uncharacterised proteins, such as the 9.3kDa protein YNQ1 from the nqo2 3'region in Paracoccus denitrificans. They have no known function. |
|
•
•
•
•
•
|
Allele |
Name: |
N-ribosyldihydronicotinamide quinone reductase 2; targeted mutation 1, Anil K Jaiswal |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nqo2/Nqo2 |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Fearnley IM |
Year: |
1992 |
Journal: |
Biochim Biophys Acta |
Title: |
Conservation of sequences of subunits of mitochondrial complex I and their relationships with other proteins. |
Volume: |
1140 |
Issue: |
2 |
Pages: |
105-34 |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Respiratory-chain NADH dehydrogenase () [](also known as complex I or NADH-ubiquinone oxidoreductase) is an oligomeric enzymatic complex located in the inner mitochondrial membrane which also seems to exist in the chloroplast and in cyanobacteria (as a NADH-plastoquinone oxidoreductase). Among the 25 to 30 polypeptide subunits of this bioenergetic enzyme complex there is one with a molecular weight of 24 Kd (in mammals), which is a component of the iron-sulfur (IP) fragment of the enzyme. It seems to bind a 2Fe-2S iron-sulfur cluster. The 24 Kd subunit is nuclear encoded, as a precursor form with a transit peptide in mammals, and in Neurospora crassa.The 24 Kd subunit is highly similar to [, ]: Subunit E of Escherichia coli NADH-ubiquinone oxidoreductase (gene nuoE) and Subunit NQO2 of Paracoccus denitrificans NADH-ubiquinone oxidoreductase. |
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Publication |
First Author: |
Vasiliou V |
Year: |
1994 |
Journal: |
Pharmacogenetics |
Title: |
Mouse dioxin-inducible NAD(P)H: menadione oxidoreductase: NMO1 cDNA sequence and genetic differences in mRNA levels. |
Volume: |
4 |
Issue: |
6 |
Pages: |
341-8 |
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Publication |
First Author: |
Brouillette J |
Year: |
2008 |
Journal: |
Neurobiol Aging |
Title: |
Transthyretin: a key gene involved in the maintenance of memory capacities during aging. |
Volume: |
29 |
Issue: |
11 |
Pages: |
1721-32 |
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Protein |
Organism: |
Mus musculus/domesticus |
Length: |
248
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Fragment?: |
false |
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Publication |
First Author: |
Weidner U |
Year: |
1993 |
Journal: |
J Mol Biol |
Title: |
The gene locus of the proton-translocating NADH: ubiquinone oxidoreductase in Escherichia coli. Organization of the 14 genes and relationship between the derived proteins and subunits of mitochondrial complex I. |
Volume: |
233 |
Issue: |
1 |
Pages: |
109-22 |
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Publication |
First Author: |
Weiss H |
Year: |
1991 |
Journal: |
Eur J Biochem |
Title: |
The respiratory-chain NADH dehydrogenase (complex I) of mitochondria. |
Volume: |
197 |
Issue: |
3 |
Pages: |
563-76 |
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