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Search results 1 to 100 out of 729 for Nras

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Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
4893 | NRAS
Type: gene
Organism: human
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Gene
506322 | NRAS
Type: gene
Organism: cattle
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Gene
24605 | Nras
Type: gene
Organism: rat
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Gene
403872 | NRAS
Type: gene
Organism: dog, domestic
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Gene
742713 | NRAS
Type: gene
Organism: chimpanzee
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Gene
30380 | nras
Type: gene
Organism: zebrafish
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Gene
709089 | NRAS
Type: gene
Organism: macaque, rhesus
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Gene
549517 | nras
Type: gene
Organism: frog, western clawed
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Gene
key_20610 | NRAS
Type: gene
Organism: cat, domestic
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Gene
419885 | NRAS
Type: gene
Organism: chicken
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Protein Coding Gene
MGI:97376 | Nras
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
2835730 | J:9173
First Author: Chang HY
Year: 1987
Journal: Oncogene Res
Title: Mouse N-ras genes: organization of the functional locus and of a truncated cDNA-like pseudogene.
Volume: 1
Issue: 2
Pages: 129-36
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Publication
25252692 | J:220627
First Author: Burd CE
Year: 2014
Journal: Cancer Discov
Title: Mutation-specific RAS oncogenicity explains NRAS codon 61 selection in melanoma.
Volume: 4
Issue: 12
Pages: 1418-29
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Publication
16369533 | J:106133
First Author: Takahashi C
Year: 2006
Journal: Nat Genet
Title: Nras loss induces metastatic conversion of Rb1-deficient neuroendocrine thyroid tumor.
Volume: 38
Issue: 1
Pages: 118-23
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Publication
35672316 | J:325350
First Author: Murphy BM
Year: 2022
Journal: Nat Commun
Title: Enhanced BRAF engagement by NRAS mutants capable of promoting melanoma initiation.
Volume: 13
Issue: 1
Pages: 3153
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Publication
37317963 | J:359437
 
First Author: Ren JG
Year: 2023
Journal: J Clin Invest
Title: RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
Volume: 133
Issue: 12
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Publication
22983396 | J:238049
First Author: Kwong LN
Year: 2012
Journal: Nat Med
Title: Oncogenic NRAS signaling differentially regulates survival and proliferation in melanoma.
Volume: 18
Issue: 10
Pages: 1503-10
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Publication
38743908 | J:349161
     
First Author: Nozawa A
Year: 2024
Journal: Hum Mol Genet
Title: Lymphatic endothelial cell-specific NRAS p.Q61R mutant embryos show abnormal lymphatic vessel morphogenesis.
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Publication
15831708 | J:101142
First Author: Wiesner SM
Year: 2005
Journal: Blood
Title: Repressible transgenic model of NRAS oncogene-driven mast cell disease in the mouse.
Volume: 106
Issue: 3
Pages: 1054-62
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Publication
27109513 | J:234854
First Author: Kong G
Year: 2016
Journal: Leukemia
Title: The ability of endogenous Nras oncogenes to initiate leukemia is codon-dependent.
Volume: 30
Issue: 9
Pages: 1935-8
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Publication
22876308 | J:189834
First Author: Lassen LB
Year: 2012
Journal: PLoS One
Title: Nras overexpression results in granulocytosis, T-cell expansion and early lethality in mice.
Volume: 7
Issue: 8
Pages: e42216
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Publication
23418499 | J:199340
First Author: Ballarín-González B
Year: 2013
Journal: PLoS One
Title: Deregulated Nras expression in knock-in animals harboring a gammaretroviral long terminal repeat at the Nras/Csde1 locus.
Volume: 8
Issue: 2
Pages: e56029
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Publication
24284627 | J:207827
First Author: Li Q
Year: 2013
Journal: Nature
Title: Oncogenic Nras has bimodal effects on stem cells that sustainably increase competitiveness.
Volume: 504
Issue: 7478
Pages: 143-147
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Publication
25815427 | J:222644
First Author: Pawlikowski JS
Year: 2015
Journal: J Invest Dermatol
Title: Acute Inhibition of MEK Suppresses Congenital Melanocytic Nevus Syndrome in a Murine Model Driven by Activated NRAS and Wnt Signaling.
Volume: 135
Issue: 8
Pages: 2093-2101
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Publication
29275866 | J:253744
First Author: Kunimoto H
Year: 2018
Journal: Cancer Cell
Title: Cooperative Epigenetic Remodeling by TET2 Loss and NRAS Mutation Drives Myeloid Transformation and MEK Inhibitor Sensitivity.
Volume: 33
Issue: 1
Pages: 44-59.e8
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Publication
21586752 | J:174880
First Author: Wang J
Year: 2011
Journal: Blood
Title: Endogenous oncogenic Nras mutation initiates hematopoietic malignancies in a dose- and cell type-dependent manner.
Volume: 118
Issue: 2
Pages: 368-79
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Publication
31703632 | J:290465
First Author: Shi X
Year: 2019
Journal: BMC Cancer
Title: Cooperation of Dnmt3a R878H with Nras G12D promotes leukemogenesis in knock-in mice: a pilot study.
Volume: 19
Issue: 1
Pages: 1072
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Publication
37847561 | J:343436
 
First Author: Rajagopalan A
Year: 2023
Journal: J Clin Invest
Title: A gain-of-function p53 mutant synergizes with oncogenic NRAS to promote acute myeloid leukemia in mice.
Volume: 133
Issue: 24
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Publication
33512434 | J:307795
First Author: Wen Z
Year: 2021
Journal: Blood
Title: Nras Q61R/+ and Kras-/- cooperate to downregulate Rasgrp1 and promote lympho-myeloid leukemia in early T-cell precursors.
Volume: 137
Issue: 23
Pages: 3259-3271
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Publication
20921338 | J:167384
First Author: Wang J
Year: 2010
Journal: Blood
Title: Endogenous oncogenic Nras mutation promotes aberrant GM-CSF signaling in granulocytic/monocytic precursors in a murine model of chronic myelomonocytic leukemia.
Volume: 116
Issue: 26
Pages: 5991-6002
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Publication
23303902 | J:198244
First Author: Pedersen M
Year: 2013
Journal: Cancer Discov
Title: Primary melanoma of the CNS in children is driven by congenital expression of oncogenic NRAS in melanocytes.
Volume: 3
Issue: 4
Pages: 458-469
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Publication
34699595 | J:322740
First Author: You X
Year: 2022
Journal: Blood
Title: Asxl1 loss cooperates with oncogenic Nras in mice to reprogram the immune microenvironment and drive leukemic transformation.
Volume: 139
Issue: 7
Pages: 1066-1079
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Publication
31685810 | J:293435
First Author: Fuentes-Mateos R
Year: 2019
Journal: Cell Death Dis
Title: Concomitant deletion of HRAS and NRAS leads to pulmonary immaturity, respiratory failure and neonatal death in mice.
Volume: 10
Issue: 11
Pages: 838
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Publication
3865197 | J:8114
First Author: Guerrero I
Year: 1985
Journal: Proc Natl Acad Sci U S A
Title: Loss of the normal N-ras allele in a mouse thymic lymphoma induced by a chemical carcinogen.
Volume: 82
Issue: 23
Pages: 7810-4
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Publication
25189354 | J:316236
First Author: Coleman DJ
Year: 2015
Journal: Mol Cancer Res
Title: Loss of keratinocytic RXRα combined with activated CDK4 or oncogenic NRAS generates UVB-induced melanomas via loss of p53 and PTEN in the tumor microenvironment.
Volume: 13
Issue: 1
Pages: 186-96
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Publication
28341702 | J:263734
First Author: Giannou AD
Year: 2017
Journal: EMBO Mol Med
Title: NRAS destines tumor cells to the lungs.
Volume: 9
Issue: 5
Pages: 672-686
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UniProt Feature
UniProt Feature
Begin: 1
Description: GTPase NRas
Type: chain
End: 186
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Publication
34948179 | J:316844
 
First Author: Ragab N
Year: 2021
Journal: Int J Mol Sci
Title: Oncogenic NRAS Accelerates Rhabdomyosarcoma Formation When Occurring within a Specific Time Frame during Tumor Development in Mice.
Volume: 22
Issue: 24
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Publication
32640012 | J:351659
First Author: Wen Z
Year: 2021
Journal: Blood
Title: Expression of NrasQ61R and MYC transgene in germinal center B cells induces a highly malignant multiple myeloma in mice.
Volume: 137
Issue: 1
Pages: 61-74
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Publication
27055865 | J:232797
First Author: Kong G
Year: 2016
Journal: Leukemia
Title: Loss of wild-type Kras promotes activation of all Ras isoforms in oncogenic Kras-induced leukemogenesis.
Volume: 30
Issue: 7
Pages: 1542-51
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Publication
18952898 | J:144858
First Author: Kim WI
Year: 2009
Journal: Blood
Title: RAS oncogene suppression induces apoptosis followed by more differentiated and less myelosuppressive disease upon relapse of acute myeloid leukemia.
Volume: 113
Issue: 5
Pages: 1086-96
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Publication
39723841 | J:361452
First Author: McDaniel CG
Year: 2025
Journal: Pediatr Blood Cancer
Title: Lyve1-Driven Nras(Q61R) Causes Edema, Enlarged Lymphatic Vessels, and Hepatic Vascular Defects in Embryonic Mice.
Volume: 72
Issue: 3
Pages: e31492
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Publication
2174525 | J:72258
First Author: Mangues R
Year: 1990
Journal: Oncogene
Title: Tumorigenesis and male sterility in transgenic mice expressing a MMTV/N-ras oncogene.
Volume: 5
Issue: 10
Pages: 1491-7
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Publication
9181520 | J:72132
First Author: Mediavilla MD
Year: 1997
Journal: J Pineal Res
Title: Effects of melatonin on mammary gland lesions in transgenic mice overexpressing N-ras proto-oncogene.
Volume: 22
Issue: 2
Pages: 86-94
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Publication
1328989 | J:72259
First Author: Mangues R
Year: 1992
Journal: Oncogene
Title: Overexpression of the N-ras proto-oncogene, not somatic mutational activation, associated with malignant tumors in transgenic mice.
Volume: 7
Issue: 10
Pages: 2073-6
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Publication
9515813 | J:46415
First Author: Mangues R
Year: 1998
Journal: Cancer Res
Title: Antitumor effect of a farnesyl protein transferase inhibitor in mammary and lymphoid tumors overexpressing N-ras in transgenic mice.
Volume: 58
Issue: 6
Pages: 1253-9
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Publication
28497782 | J:335349
 
First Author: Dorard C
Year: 2017
Journal: Nat Commun
Title: RAF proteins exert both specific and compensatory functions during tumour progression of NRAS-driven melanoma.
Volume: 8
Pages: 15262
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Publication
30377195 | J:269361
First Author: You X
Year: 2018
Journal: Blood
Title: Unique dependence on Sos1 in Kras G12D -induced leukemogenesis.
Volume: 132
Issue: 24
Pages: 2575-2579
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Publication
33283624 | J:335419
First Author: Assenmacher CA
Year: 2021
Journal: J Histochem Cytochem
Title: Classification and Grading of Melanocytic Lesions in a Mouse Model of NRAS-driven Melanomagenesis.
Volume: 69
Issue: 3
Pages: 203-218
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Publication
22718121 | J:335347
First Author: Li A
Year: 2012
Journal: J Invest Dermatol
Title: Activated mutant NRas(Q61K) drives aberrant melanocyte signaling, survival, and invasiveness via a Rac1-dependent mechanism.
Volume: 132
Issue: 11
Pages: 2610-21
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Publication
23687087 | J:201009
First Author: Wang J
Year: 2013
Journal: Blood
Title: Nras(G12D/+) promotes leukemogenesis by aberrantly regulating hematopoietic stem cell functions.
Volume: 121
Issue: 26
Pages: 5203-7
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Publication
23274911 | J:198246
First Author: Wang Y
Year: 2013
Journal: Cancer Discov
Title: Mutant N-RAS protects colorectal cancer cells from stress-induced apoptosis and contributes to cancer development and progression.
Volume: 3
Issue: 3
Pages: 294-307
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Publication
28343944 | J:317017
 
First Author: Campagne C
Year: 2017
Journal: Cell Signal
Title: RACK1 cooperates with NRASQ61K to promote melanoma in vivo.
Volume: 36
Pages: 255-266
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Publication
27135738 | J:239472
First Author: Souroullas GP
Year: 2016
Journal: Nat Med
Title: An oncogenic Ezh2 mutation induces tumors through global redistribution of histone 3 lysine 27 trimethylation.
Volume: 22
Issue: 6
Pages: 632-40
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Publication
32219446 | J:289386
First Author: Zambetti NA
Year: 2020
Journal: Blood
Title: Genetic disruption of N-RasG12D palmitoylation perturbs hematopoiesis and prevents myeloid transformation in mice.
Volume: 135
Issue: 20
Pages: 1772-1782
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Publication
21163920 | J:169608
First Author: Li Q
Year: 2011
Journal: Blood
Title: Hematopoiesis and leukemogenesis in mice expressing oncogenic NrasG12D from the endogenous locus.
Volume: 117
Issue: 6
Pages: 2022-32
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Publication
23733505 | J:204263
First Author: Xu J
Year: 2013
Journal: Cancer Discov
Title: Dominant role of oncogene dosage and absence of tumor suppressor activity in Nras-driven hematopoietic transformation.
Volume: 3
Issue: 9
Pages: 993-1001
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Publication
25361812 | J:220778
First Author: Burgess MR
Year: 2014
Journal: Blood
Title: Preclinical efficacy of MEK inhibition in Nras-mutant AML.
Volume: 124
Issue: 26
Pages: 3947-55
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Publication
24812670 | J:212912
First Author: Kong G
Year: 2014
Journal: J Clin Invest
Title: Combined MEK and JAK inhibition abrogates murine myeloproliferative neoplasm.
Volume: 124
Issue: 6
Pages: 2762-73
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Publication
31443434 | J:293518
 
First Author: Dong Y
Year: 2019
Journal: Cells
Title: Synergy of NUP98-HOXA10 Fusion Gene and NrasG12D Mutation Preserves the Stemness of Hematopoietic Stem Cells on Culture Condition.
Volume: 8
Issue: 9
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Publication
32569596 | J:299503
First Author: Rahman H
Year: 2021
Journal: J Invest Dermatol
Title: Aspirin Protects Melanocytes and Keratinocytes against UVB-Induced DNA Damage In Vivo.
Volume: 141
Issue: 1
Pages: 132-141.e3
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Protein
P08556
Organism: Mus musculus/domesticus
Length: 189  
Fragment?: false
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Protein
Q4FJP3
Organism: Mus musculus/domesticus
Length: 193  
Fragment?: false
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Protein
A0A0G2JE25
Organism: Mus musculus/domesticus
Length: 150  
Fragment?: true
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Protein
A0A0G2JGP4
Organism: Mus musculus/domesticus
Length: 183  
Fragment?: true
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Protein
A0A0G2JGM2
Organism: Mus musculus/domesticus
Length: 74  
Fragment?: true
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Protein
E9PVD5
Organism: Mus musculus/domesticus
Length: 46  
Fragment?: false
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Publication
2676841 | J:10048
First Author: Buchberg AM
Year: 1989
Journal: Genomics
Title: Localization of the murine macrophage colony-stimulating factor gene to chromosome 3 using interspecific backcross analysis.
Volume: 5
Issue: 2
Pages: 363-7
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Publication
18566322 | J:138720
First Author: Slape C
Year: 2008
Journal: Blood
Title: Leukemic transformation in mice expressing a NUP98-HOXD13 transgene is accompanied by spontaneous mutations in Nras, Kras, and Cbl.
Volume: 112
Issue: 5
Pages: 2017-9
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Publication
38711167 | J:354272
First Author: Pastura P
Year: 2024
Journal: Pediatr Blood Cancer
Title: NRAS(Q61R) mutation drives elevated angiopoietin-2 expression in human endothelial cells and a genetic mouse model.
Volume: 71
Issue: 7
Pages: e31032
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Publication
18372904 | J:132357
First Author: Haigis KM
Year: 2008
Journal: Nat Genet
Title: Differential effects of oncogenic K-Ras and N-Ras on proliferation, differentiation and tumor progression in the colon.
Volume: 40
Issue: 5
Pages: 600-8
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Publication
28117393 | J:320537
 
First Author: Newlaczyl AU
Year: 2017
Journal: Sci Rep
Title: Quantification of spatiotemporal patterns of Ras isoform expression during development.
Volume: 7
Pages: 41297
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Publication
11679445 | J:72416
First Author: Lyons PA
Year: 2001
Journal: Diabetes
Title: Mapping by genetic interaction: high-resolution congenic mapping of the type 1 diabetes loci Idd10 and Idd18 in the NOD mouse.
Volume: 50
Issue: 11
Pages: 2633-7
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Publication
35561684 | J:325979
First Author: Choi YS
Year: 2022
Journal: Cell
Title: Topical therapy for regression and melanoma prevention of congenital giant nevi.
Volume: 185
Issue: 12
Pages: 2071-2085.e12
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Publication
27815262 | J:238921
First Author: Zhang J
Year: 2017
Journal: Blood
Title: p53-/- synergizes with enhanced NrasG12D signaling to transform megakaryocyte-erythroid progenitors in acute myeloid leukemia.
Volume: 129
Issue: 3
Pages: 358-370
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Publication
25801914 | J:224952
First Author: Chang YI
Year: 2015
Journal: Leukemia
Title: Loss of Dnmt3a and endogenous Kras(G12D/+) cooperate to regulate hematopoietic stem and progenitor cell functions in leukemogenesis.
Volume: 29
Issue: 9
Pages: 1847-56
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Publication
28835438 | J:246313
First Author: Dovey OM
Year: 2017
Journal: Blood
Title: Molecular synergy underlies the co-occurrence patterns and phenotype of NPM1-mutant acute myeloid leukemia.
Volume: 130
Issue: 17
Pages: 1911-1922
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Publication
27911940 | J:250854
First Author: Weyandt JD
Year: 2016
Journal: PLoS One
Title: Isoform-Specific Effects of Wild-Type Ras Genes on Carcinogen-Induced Lung Tumorigenesis in Mice.
Volume: 11
Issue: 12
Pages: e0167205
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Publication
27741509 | J:319205
First Author: Nowacka JD
Year: 2016
Journal: Oncotarget
Title: MEK1 is required for the development of NRAS-driven leukemia.
Volume: 7
Issue: 49
Pages: 80113-80130
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Publication
8001974 | J:20389
First Author: Threadgill DS
Year: 1994
Journal: Genomics
Title: Syntenic assignment of human chromosome 1 homologous loci in the bovine.
Volume: 22
Issue: 3
Pages: 626-30
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Publication
28647344 | J:252204
First Author: van Tuyn J
Year: 2017
Journal: J Invest Dermatol
Title: Oncogene-Expressing Senescent Melanocytes Up-Regulate MHC Class II, a Candidate Melanoma Suppressor Function.
Volume: 137
Issue: 10
Pages: 2197-2207
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Publication
31189531 | J:278958
First Author: Gu Z
Year: 2019
Journal: Cancer Discov
Title: Loss of EZH2 Reprograms BCAA Metabolism to Drive Leukemic Transformation.
Volume: 9
Issue: 9
Pages: 1228-1247
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Publication
17576930 | J:122592
First Author: Ha L
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: ARF functions as a melanoma tumor suppressor by inducing p53-independent senescence.
Volume: 104
Issue: 26
Pages: 10968-73
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Publication
22945650 | J:203248
First Author: To MD
Year: 2013
Journal: Oncogene
Title: Interactions between wild-type and mutant Ras genes in lung and skin carcinogenesis.
Volume: 32
Issue: 34
Pages: 4028-33
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Publication
35904492 | J:330081
First Author: Chen S
Year: 2022
Journal: Cancer Discov
Title: Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Volume: 12
Issue: 10
Pages: 2434-2453
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Publication
35082403 | J:322607
First Author: Wen Z
Year: 2022
Journal: Leukemia
Title: Tcof1 haploinsufficiency promotes early T cell precursor-like leukemia in NrasQ61R/+ mice.
Volume: 36
Issue: 4
Pages: 1167-1170
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Publication
27236105 | J:235072
First Author: Halaban R
Year: 2016
Journal: J Invest Dermatol
Title: RASopathy Gene Mutations in Melanoma.
Volume: 136
Issue: 9
Pages: 1755-9
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Protein Coding Gene
MGP_CAROLIEiJ_G0025445 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0027689 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0027648 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0027614 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0027661 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0027390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_97376 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0028104 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0026847 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0027365 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0027508 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0027476 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0027615 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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