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Search results 1 to 100 out of 1145 for Nrg1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Domain
Type: Family
Description: Neuregulins are a sub-family of EGF-like molecules that have been shown to play multiple essential roles in vertebrate embryogenesis including: cardiac development, Schwann cell and oligodendrocyte differentiation, some aspects of neuronal development, as well as the formation of neuromuscular synapses [, ]. Included in the family are heregulin; neu differentiation factor; acetylcholine receptor synthesis stimulator; glial growth factor; and sensory and motor-neuron derived factor []. Multiple family members are generated by alternate splicing or by use of several cell type-specific transcription initiation sites. In general, they bind to and activate the erbB family of receptor tyrosine kinases (erbB2 (HER2), erbB3 (HER3), and erbB4 (HER4)), functioning both as heterodimers and homodimers.The transmembrane forms of neuregulin 1 (NRG1) are present within synaptic vesicles, including those containing glutamate []. After exocytosis, NRG1 is in the presynaptic membrane, where the ectodomain of NRG1 may be cleaved off. The ectodomain then migrates across the synaptic cleft and binds to and activates a member of the EGF-receptor family on the postsynaptic membrane. This has been shown to increase the expression of certain glutamate-receptor subunits. NRG1 appears to signal for glutamate-receptor subunit expression, localisation, and /or phosphorylation facilitating subsequent glutamate transmission. The NRG1 gene has been identified as a potential gene determining susceptibility to schizophrenia by a combination of genetic linkage and association approaches [].
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Pu W
Year: 2018
Journal: Circ Res
Title: Genetic Targeting of Organ-Specific Blood Vessels.
Volume: 123
Issue: 1
Pages: 86-99
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Stefansson H
Year: 2002
Journal: Am J Hum Genet
Title: Neuregulin 1 and susceptibility to schizophrenia.
Volume: 71
Issue: 4
Pages: 877-92
Publication
First Author: Vartanian T
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Failure of spinal cord oligodendrocyte development in mice lacking neuregulin.
Volume: 96
Issue: 2
Pages: 731-5
Allele
Name: neuregulin 1; endonuclease-mediated mutation 1, Bin Zhou
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Allele
Name: neuregulin 1; endonuclease-mediated mutation 2, Bin Zhou
Allele Type: Endonuclease-mediated
Attribute String: Conditional ready, Inducible, Recombinase
Publication categories: ProxyCollection
Publication
First Author: Tao Y
Year: 2009
Journal: Proc Natl Acad Sci U S A
Title: Erbin regulates NRG1 signaling and myelination.
Volume: 106
Issue: 23
Pages: 9477-82
Publication
First Author: Velanac V
Year: 2012
Journal: Glia
Title: Bace1 processing of NRG1 type III produces a myelin-inducing signal but is not essential for the stimulation of myelination.
Volume: 60
Issue: 2
Pages: 203-17
Publication      
First Author: Falls D
Year: 2003
Journal: Personal Communication
Title: Physical mapping of Nrg1 to mouse Chromosome 8
Publication
First Author: Fledrich R
Year: 2019
Journal: Nat Commun
Title: NRG1 type I dependent autoparacrine stimulation of Schwann cells in onion bulbs of peripheral neuropathies.
Volume: 10
Issue: 1
Pages: 1467
Publication
First Author: Arthur-Farraj P
Year: 2011
Journal: Glia
Title: Mouse schwann cells need both NRG1 and cyclic AMP to myelinate.
Volume: 59
Issue: 5
Pages: 720-33
Publication
First Author: Fazzari P
Year: 2010
Journal: Nature
Title: Control of cortical GABA circuitry development by Nrg1 and ErbB4 signalling.
Volume: 464
Issue: 7293
Pages: 1376-80
Publication  
First Author: Zhong C
Year: 2017
Journal: eNeuro
Title: Axonal Type III Nrg1 Controls Glutamate Synapse Formation and GluA2 Trafficking in Hippocampal-Accumbens Connections.
Volume: 4
Issue: 1
Publication
First Author: Kawashima I
Year: 2014
Journal: Mol Endocrinol
Title: Targeted disruption of Nrg1 in granulosa cells alters the temporal progression of oocyte maturation.
Volume: 28
Issue: 5
Pages: 706-21
Publication  
First Author: Zieba J
Year: 2020
Journal: Behav Brain Res
Title: Behavioural effects of high fat diet in adult Nrg1 type III transgenic mice.
Volume: 377
Pages: 112217
Publication
First Author: Schroering A
Year: 1998
Journal: J Biol Chem
Title: Sensory and motor neuron-derived factor is a transmembrane heregulin that is expressed on the plasma membrane with the active domain exposed to the extracellular environment.
Volume: 273
Issue: 46
Pages: 30643-50
Publication
First Author: Burden S
Year: 1997
Journal: Neuron
Title: Neuregulins and their receptors: a versatile signaling module in organogenesis and oncogenesis.
Volume: 18
Issue: 6
Pages: 847-55
Publication  
First Author: Gregoire EP
Year: 2018
Journal: Mol Cell Endocrinol
Title: NRG1 signalling regulates the establishment of Sertoli cell stock in the mouse testis.
Volume: 478
Pages: 17-31
Protein
Organism: Mus musculus
Length: 76  
Fragment?: true
Protein
Organism: Mus musculus
Length: 285  
Fragment?: false
Protein
Organism: Mus musculus
Length: 300  
Fragment?: true
Protein
Organism: Mus musculus
Length: 695  
Fragment?: false
Protein
Organism: Mus musculus
Length: 311  
Fragment?: false
Protein
Organism: Mus musculus
Length: 483  
Fragment?: false
Protein
Organism: Mus musculus
Length: 700  
Fragment?: false
Protein
Organism: Mus musculus
Length: 483  
Fragment?: false
Publication
First Author: Dejaegere T
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Deficiency of Aph1B/C-gamma-secretase disturbs Nrg1 cleavage and sensorimotor gating that can be reversed with antipsychotic treatment.
Volume: 105
Issue: 28
Pages: 9775-80
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271120
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271220
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271224
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754320
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754324
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 8
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753720
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753724
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691319
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the cerebral cortex and the ganglionic eminences.
Specimen Num: 5
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271820
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is weak staining in the mantle zone of the mam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and supramam zones and the TT.
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271824
Pattern: Non-Uniform
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is weak staining in the mantle zone of the mam zone. Staining is either absent or ubiquitous in the mantle zone of the premam and supramam zones.
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1690819
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus, the prethalamus, dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH, the anterior and posterior IDs, the premam, mam and supramam zones and the TT.
Specimen Num: 5
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753922
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 7
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1691119
Pattern: Not Specified
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: There is weak staining in the postmitotic neurons in the intermediate zone and cortical plate of the cerebral cortex and in the mantle zone of the ganglionic eminences.
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754720
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 6
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Very strong
Sex: Not Specified
Emaps: EMAPS:1754724
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: There is very strong staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271020
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones and the TT.
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271024
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the premam, mam and supramam zones.
Specimen Num: 8
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3266520
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3266524
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular and mantle zones of the ganglionic eminences.
Specimen Num: 8
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1690619
Pattern: Non-Uniform
Stage: TS19
Assay Id: MGI:4450868
Age: embryonic day 11.5
Image: Nrg1 - E11.5
Note: Staining is moderate in the MZ of the prethalamus & weak in the mam zone. Staining is either absent or ubiquitous in the MZ of the dorsal thalamus, dorsal & ventral POAs, PVH, VMH & ARH nuclei, AVH, anterior & posterior IDs, premam & supramam zones & TT.
Detected: true
Specimen Num: 5
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754120
Pattern: Non-Uniform
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: There is moderate staining in the mantle zone of the prethalamus. Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus.
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754124
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the mantle zone of the dorsal thalamus and prethalamus.
Specimen Num: 8
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the cortical plate of the cerebral cortex.
Specimen Num: 7
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the postmitotic neurons in the intermediate zone of the cerebral cortex.
Specimen Num: 7
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754322
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal thalamus and prethalamus.
Specimen Num: 7
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1753722
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is moderate staining in the mantle zone of the PVH nucleus. Staining is either absent or ubiquitous in the mantle zone of the dorsal and ventral POAs, the VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3271822
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: Staining is either absent or ubiquitous in the mantle zone of the premam, mam and supramam zones and the TT.
Specimen Num: 7
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753920
Pattern: Not Specified
Stage: TS20
Assay Id: MGI:4450868
Age: embryonic day 12.5
Image: Nrg1 - E12.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, VMH and ARH nuclei, the AVH and anterior and posterior IDs.
Specimen Num: 6
GXD Expression  
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1753924
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:4450868
Age: embryonic day 16.5
Image: Nrg1 - E16.5
Note: Staining is either absent or ubiquitous in the ventricular zone of the dorsal and ventral POAs, the PVH, SCH, DMH, VMH and ARH nuclei, the AVH, the DAH and the PH.
Specimen Num: 8
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is strong staining in the ventricular zone of the cerebral cortex.
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3271022
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is weak staining in the ventricular zone of the mam zone. Staining is either absent or ubiquitous in the ventricular zone of the premam and supramam zones and the TT.
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3266522
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is strong staining in the ventricular zone of the ganglionic eminences. Staining is either absent or ubiquitous in the mantle zone of the ganglionic eminences.
Detected: true
Specimen Num: 7
GXD Expression
Probe: MGI:4442675
Assay Type: RNA in situ
Annotation Date: 2010-05-13
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1754122
Pattern: Non-Uniform
Stage: TS22
Assay Id: MGI:4450868
Age: embryonic day 14.5
Image: Nrg1 - E14.5
Note: There is moderate staining in the mantle zone of the dorsal thalamus and weak staining in the prethalamus.
Detected: true
Specimen Num: 7
Publication
First Author: Del Monte-Nieto G
Year: 2018
Journal: Nature
Title: Control of cardiac jelly dynamics by NOTCH1 and NRG1 defines the building plan for trabeculation.
Volume: 557
Issue: 7705
Pages: 439-445
Publication
First Author: Canetta SE
Year: 2011
Journal: PLoS One
Title: Type III Nrg1 back signaling enhances functional TRPV1 along sensory axons contributing to basal and inflammatory thermal pain sensation.
Volume: 6
Issue: 9
Pages: e25108
Publication
First Author: Chen B
Year: 2011
Journal: PLoS One
Title: An ENU-induced mutation of Nrg1 causes dilated pupils and a reduction in muscarinic receptors in the sphincter pupillae.
Volume: 6
Issue: 9
Pages: e25176
Publication
First Author: Parra LM
Year: 2015
Journal: Mol Cell Biol
Title: Distinct Intracellular Domain Substrate Modifications Selectively Regulate Ectodomain Cleavage of NRG1 or CD44.
Volume: 35
Issue: 19
Pages: 3381-95
Protein
Organism: Mus musculus
Length: 459  
Fragment?: false
Protein
Organism: Mus musculus
Length: 423  
Fragment?: false
Protein
Organism: Mus musculus
Length: 663  
Fragment?: false
Protein
Organism: Mus musculus
Length: 462  
Fragment?: false
Protein
Organism: Mus musculus
Length: 603  
Fragment?: false
Protein
Organism: Mus musculus
Length: 858  
Fragment?: false
Protein
Organism: Mus musculus
Length: 604  
Fragment?: false
Protein
Organism: Mus musculus
Length: 645  
Fragment?: false
Protein
Organism: Mus musculus
Length: 637  
Fragment?: false
Protein
Organism: Mus musculus
Length: 433  
Fragment?: false
Protein
Organism: Mus musculus
Length: 485  
Fragment?: false
Protein
Organism: Mus musculus
Length: 640  
Fragment?: false
Protein
Organism: Mus musculus
Length: 206  
Fragment?: true
Protein
Organism: Mus musculus
Length: 241  
Fragment?: false
Protein
Organism: Mus musculus
Length: 420  
Fragment?: false
Protein
Organism: Mus musculus
Length: 247  
Fragment?: false
Protein
Organism: Mus musculus
Length: 472  
Fragment?: true
Protein
Organism: Mus musculus
Length: 324  
Fragment?: true
Publication
First Author: Deakin IH
Year: 2012
Journal: Cereb Cortex
Title: Transgenic overexpression of the type I isoform of neuregulin 1 affects working memory and hippocampal oscillations but not long-term potentiation.
Volume: 22
Issue: 7
Pages: 1520-9
Publication
First Author: Salvany S
Year: 2019
Journal: FASEB J
Title: Localization and dynamic changes of neuregulin-1 at C-type synaptic boutons in association with motor neuron injury and repair.
Volume: 33
Issue: 7
Pages: 7833-7851
Publication
First Author: Stassart RM
Year: 2013
Journal: Nat Neurosci
Title: A role for Schwann cell-derived neuregulin-1 in remyelination.
Volume: 16
Issue: 1
Pages: 48-54
Publication
First Author: Liu X
Year: 1998
Journal: Proc Natl Acad Sci U S A
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Year: 2003
Journal: J Neurosci
Title: Hypertrophic neuropathies and malignant peripheral nerve sheath tumors in transgenic mice overexpressing glial growth factor beta3 in myelinating Schwann cells.
Volume: 23
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Year: 2004
Journal: Science
Title: Axonal neuregulin-1 regulates myelin sheath thickness.
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First Author: Bao J
Year: 2003
Journal: J Cell Biol
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Volume: 161
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First Author: Lee YI
Year: 2016
Journal: Proc Natl Acad Sci U S A
Title: Neuregulin1 displayed on motor axons regulates terminal Schwann cell-mediated synapse elimination at developing neuromuscular junctions.
Volume: 113
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First Author: Brinkmann BG
Year: 2008
Journal: Neuron
Title: Neuregulin-1/ErbB signaling serves distinct functions in myelination of the peripheral and central nervous system.
Volume: 59
Issue: 4
Pages: 581-95
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First Author: Cheret C
Year: 2013
Journal: EMBO J
Title: Bace1 and Neuregulin-1 cooperate to control formation and maintenance of muscle spindles.
Volume: 32
Issue: 14
Pages: 2015-28