|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 967 for Ntrk2

<< First    < Previous  |  Next >    Last >>
0.023s

Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: An JJ
Year: 2020
Journal: Nat Commun
Title: TrkB-expressing paraventricular hypothalamic neurons suppress appetite through multiple neurocircuits.
Volume: 11
Issue: 1
Pages: 1729
Publication
First Author: Liao GY
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: TrkB-expressing neurons in the dorsomedial hypothalamus are necessary and sufficient to suppress homeostatic feeding.
Volume: 116
Issue: 8
Pages: 3256-3261
Publication
First Author: An JJ
Year: 2015
Journal: Cell Metab
Title: Discrete BDNF Neurons in the Paraventricular Hypothalamus Control Feeding and Energy Expenditure.
Volume: 22
Issue: 1
Pages: 175-88
Publication
First Author: Boyle KA
Year: 2019
Journal: Cell Rep
Title: Defining a Spinal Microcircuit that Gates Myelinated Afferent Input: Implications for Tactile Allodynia.
Volume: 28
Issue: 2
Pages: 526-540.e6
Publication
First Author: Barrios J
Year: 2017
Journal: FASEB J
Title: Early life allergen-induced mucus overproduction requires augmented neural stimulation of pulmonary neuroendocrine cell secretion.
Volume: 31
Issue: 9
Pages: 4117-4128
Publication
First Author: Kuehn ED
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Tiling and somatotopic alignment of mammalian low-threshold mechanoreceptors.
Volume: 116
Issue: 19
Pages: 9168-9177
Publication
First Author: Wu P
Year: 2018
Journal: PLoS One
Title: Characterization of sensory neuronal subtypes innervating mouse tongue.
Volume: 13
Issue: 11
Pages: e0207069
Publication
First Author: Rutlin M
Year: 2014
Journal: Cell
Title: The cellular and molecular basis of direction selectivity of Aδ-LTMRs.
Volume: 159
Issue: 7
Pages: 1640-51
Publication
First Author: Bai L
Year: 2015
Journal: Cell
Title: Genetic Identification of an Expansive Mechanoreceptor Sensitive to Skin Stroking.
Volume: 163
Issue: 7
Pages: 1783-1795
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Liu Y
Year: 2012
Journal: Science
Title: Sexually dimorphic BDNF signaling directs sensory innervation of the mammary gland.
Volume: 338
Issue: 6112
Pages: 1357-60
Publication
First Author: Zimmerman AL
Year: 2019
Journal: Neuron
Title: Distinct Modes of Presynaptic Inhibition of Cutaneous Afferents and Their Functions in Behavior.
Volume: 102
Issue: 2
Pages: 420-434.e8
Publication  
First Author: Neubarth NL
Year: 2020
Journal: Science
Title: Meissner corpuscles and their spatially intermingled afferents underlie gentle touch perception.
Volume: 368
Issue: 6497
Allele
Name: neurotrophic tyrosine kinase, receptor, type 2; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Protein
Organism: Mus musculus
Length: 478  
Fragment?: false
Protein
Organism: Mus musculus
Length: 455  
Fragment?: false
Publication
First Author: Dalton JE
Year: 2015
Journal: PLoS Pathog
Title: The neurotrophic receptor Ntrk2 directs lymphoid tissue neovascularization during Leishmania donovani infection.
Volume: 11
Issue: 2
Pages: e1004681
Publication
First Author: Pattwell SS
Year: 2020
Journal: Nat Commun
Title: A kinase-deficient NTRK2 splice variant predominates in glioma and amplifies several oncogenic signaling pathways.
Volume: 11
Issue: 1
Pages: 2977
Publication
First Author: Kerr B
Year: 2009
Journal: Reproduction
Title: NTRK1 and NTRK2 receptors facilitate follicle assembly and early follicular development in the mouse ovary.
Volume: 138
Issue: 1
Pages: 131-40
Publication
First Author: Kumanogoh H
Year: 2008
Journal: Mol Cell Neurosci
Title: Balanced expression of various TrkB receptor isoforms from the Ntrk2 gene locus in the mouse nervous system.
Volume: 39
Issue: 3
Pages: 465-77
Allele
Name: transgene insertion, Paul A Heppenstall
Allele Type: Transgenic
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
GXD Expression    
Probe: MGI:4354366
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3270422
Stage: TS22
Assay Id: MGI:4354838
Age: embryonic day 14.5
Image: 3C & Table S5 - Ntrk2
Detected: false
Specimen Num: 1
GXD Expression
Probe: MGI:4354366
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Regionally restricted
Stage: TS22
Assay Id: MGI:4354838
Age: embryonic day 14.5
Image: 3C & Table S5 - Ntrk2
Note: Expression is present in the upper, but not the lower, cortical plate.
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4354366
Assay Type: RNA in situ
Annotation Date: 2009-08-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:4354838
Age: embryonic day 14.5
Image: 3C & Table S5 - Ntrk2
Detected: true
Specimen Num: 1
Publication
First Author: Dhandapani R
Year: 2018
Journal: Nat Commun
Title: Control of mechanical pain hypersensitivity in mice through ligand-targeted photoablation of TrkB-positive sensory neurons.
Volume: 9
Issue: 1
Pages: 1640
Allele
Name: neurotrophic tyrosine kinase, receptor, type 2; targeted mutation 3.1, David D Ginty
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: targeted mutation, mutant strain, congenic
Genotype
Symbol: Ntrk2/Ntrk2
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: hm
Has Mutant Allele: true
Genotype
Symbol: Bdnf/Bdnf<+> Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ntrk2/Ntrk2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ntrk2/Ntrk2<+>
Background: involves: 129S6/SvEvTac * C57BL/6NCr
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Ntrk2/Ntrk2<+>
Background: involves: 129S6/SvEvTac
Zygosity: cn
Has Mutant Allele: true
Publication
First Author: Irintchev A
Year: 2005
Journal: Eur J Neurosci
Title: Impacts of lesion severity and tyrosine kinase receptor B deficiency on functional outcome of femoral nerve injury assessed by a novel single-frame motion analysis in mice.
Volume: 22
Issue: 4
Pages: 802-8
Publication
First Author: Chakravarthy S
Year: 2006
Journal: Proc Natl Acad Sci U S A
Title: Postsynaptic TrkB signaling has distinct roles in spine maintenance in adult visual cortex and hippocampus.
Volume: 103
Issue: 4
Pages: 1071-6
Publication
First Author: Saiepour MH
Year: 2015
Journal: Cereb Cortex
Title: Competition and Homeostasis of Excitatory and Inhibitory Connectivity in the Adult Mouse Visual Cortex.
Volume: 25
Issue: 10
Pages: 3713-22
UniProt Feature
Begin: 829
Description: Phosphotyrosine; by NTRK2
Type: modified residue
End: 829
Publication
First Author: Baydyuk M
Year: 2011
Journal: Exp Neurol
Title: Chronic deprivation of TrkB signaling leads to selective late-onset nigrostriatal dopaminergic degeneration.
Volume: 228
Issue: 1
Pages: 118-25
Publication  
First Author: Lucas EK
Year: 2014
Journal: Behav Brain Res
Title: Mice lacking TrkB in parvalbumin-positive cells exhibit sexually dimorphic behavioral phenotypes.
Volume: 274
Pages: 219-25
Publication    
First Author: Tomassoni-Ardori F
Year: 2019
Journal: Elife
Title: Rbfox1 up-regulation impairs BDNF-dependent hippocampal LTP by dysregulating TrkB isoform expression levels.
Volume: 8
Publication
First Author: Boyd JG
Year: 2001
Journal: J Neurobiol
Title: The neurotrophin receptors, trkB and p75, differentially regulate motor axonal regeneration.
Volume: 49
Issue: 4
Pages: 314-25
Publication
First Author: Southwell DG
Year: 2012
Journal: Nature
Title: Intrinsically determined cell death of developing cortical interneurons.
Volume: 491
Issue: 7422
Pages: 109-13
Publication
First Author: Zheng K
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: TrkB signaling in parvalbumin-positive interneurons is critical for gamma-band network synchronization in hippocampus.
Volume: 108
Issue: 41
Pages: 17201-6
Publication
First Author: Xu B
Year: 2000
Journal: J Neurosci
Title: The role of brain-derived neurotrophic factor receptors in the mature hippocampus: modulation of long-term potentiation through a presynaptic mechanism involving TrkB.
Volume: 20
Issue: 18
Pages: 6888-97
Publication
First Author: Xu B
Year: 2000
Journal: Neuron
Title: Cortical degeneration in the absence of neurotrophin signaling: dendritic retraction and neuronal loss after removal of the receptor TrkB.
Volume: 26
Issue: 1
Pages: 233-45
Publication
First Author: Dorfman MD
Year: 2014
Journal: Endocrinology
Title: Loss of Ntrk2/Kiss1r signaling in oocytes causes premature ovarian failure.
Volume: 155
Issue: 8
Pages: 3098-111
Publication
First Author: Inoue K
Year: 2007
Journal: J Biol Chem
Title: The transcription factor Runx3 represses the neurotrophin receptor TrkB during lineage commitment of dorsal root ganglion neurons.
Volume: 282
Issue: 33
Pages: 24175-84
Publication
First Author: Wagner N
Year: 2005
Journal: Genes Dev
Title: Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1.
Volume: 19
Issue: 21
Pages: 2631-42
Publication
First Author: Horiguchi S
Year: 2010
Journal: Biochem Biophys Res Commun
Title: Downregulation of msh-like 2 (msx2) and neurotrophic tyrosine kinase receptor type 2 (ntrk2) in the developmental gut of KIT mutant mice.
Volume: 396
Issue: 3
Pages: 774-9
Publication
First Author: Xu B
Year: 2003
Journal: Nat Neurosci
Title: Brain-derived neurotrophic factor regulates energy balance downstream of melanocortin-4 receptor.
Volume: 6
Issue: 7
Pages: 736-42
Publication
First Author: Rico B
Year: 2002
Journal: Nat Neurosci
Title: TrkB receptor signaling is required for establishment of GABAergic synapses in the cerebellum.
Volume: 5
Issue: 3
Pages: 225-33
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Klein R
Year: 1990
Journal: Cell
Title: The trkB tyrosine protein kinase gene codes for a second neurogenic receptor that lacks the catalytic kinase domain.
Volume: 61
Issue: 4
Pages: 647-56
Publication
First Author: Ninkina N
Year: 1997
Journal: J Biol Chem
Title: TrkB variants with deletions in the leucine-rich motifs of the extracellular domain.
Volume: 272
Issue: 20
Pages: 13019-25
Publication
First Author: Klein R
Year: 1993
Journal: Cell
Title: Targeted disruption of the trkB neurotrophin receptor gene results in nervous system lesions and neonatal death.
Volume: 75
Issue: 1
Pages: 113-22
Publication
First Author: Minichiello L
Year: 1999
Journal: Neuron
Title: Essential role for TrkB receptors in hippocampus-mediated learning.
Volume: 24
Issue: 2
Pages: 401-14
Publication
First Author: Du J
Year: 2003
Journal: J Cell Biol
Title: Regulation of TrkB receptor tyrosine kinase and its internalization by neuronal activity and Ca2+ influx.
Volume: 163
Issue: 2
Pages: 385-95
Publication
First Author: Rose CR
Year: 2003
Journal: Nature
Title: Truncated TrkB-T1 mediates neurotrophin-evoked calcium signalling in glia cells.
Volume: 426
Issue: 6962
Pages: 74-8
Publication
First Author: Douma S
Year: 2004
Journal: Nature
Title: Suppression of anoikis and induction of metastasis by the neurotrophic receptor TrkB.
Volume: 430
Issue: 7003
Pages: 1034-9
Publication
First Author: Luikart BW
Year: 2005
Journal: J Neurosci
Title: TrkB has a cell-autonomous role in the establishment of hippocampal Schaffer collateral synapses.
Volume: 25
Issue: 15
Pages: 3774-86
Publication
First Author: Johnson EM
Year: 2007
Journal: J Physiol
Title: TrkB is necessary for pruning at the climbing fibre-Purkinje cell synapse in the developing murine cerebellum.
Volume: 582
Issue: Pt 2
Pages: 629-46
Publication
First Author: Liu X
Year: 2007
Journal: J Neurosci
Title: Brain-derived neurotrophic factor and TrkB modulate visual experience-dependent refinement of neuronal pathways in retina.
Volume: 27
Issue: 27
Pages: 7256-67
Publication
First Author: Ozek C
Year: 2015
Journal: Mol Metab
Title: Ablation of intact hypothalamic and/or hindbrain TrkB signaling leads to perturbations in energy balance.
Volume: 4
Issue: 11
Pages: 867-80
Publication
First Author: Lobo MK
Year: 2010
Journal: Science
Title: Cell type-specific loss of BDNF signaling mimics optogenetic control of cocaine reward.
Volume: 330
Issue: 6002
Pages: 385-90
Publication
First Author: Koo JW
Year: 2014
Journal: Neuropsychopharmacology
Title: Loss of BDNF signaling in D1R-expressing NAc neurons enhances morphine reward by reducing GABA inhibition.
Volume: 39
Issue: 11
Pages: 2646-53
Publication
First Author: Harada C
Year: 2015
Journal: Am J Pathol
Title: TrkB Signaling in Retinal Glia Stimulates Neuroprotection after Optic Nerve Injury.
Volume: 185
Issue: 12
Pages: 3238-47
Publication
First Author: Colombo E
Year: 2012
Journal: J Exp Med
Title: Stimulation of the neurotrophin receptor TrkB on astrocytes drives nitric oxide production and neurodegeneration.
Volume: 209
Issue: 3
Pages: 521-35
Publication
First Author: Xenos D
Year: 2018
Journal: Cereb Cortex
Title: Loss of TrkB Signaling in Parvalbumin-Expressing Basket Cells Results in Network Activity Disruption and Abnormal Behavior.
Volume: 28
Issue: 10
Pages: 3399-3413
Publication
First Author: Zörner B
Year: 2003
Journal: Biol Psychiatry
Title: Forebrain-specific trkB-receptor knockout mice: behaviorally more hyperactive than "depressive".
Volume: 54
Issue: 10
Pages: 972-82
Publication
First Author: von Bohlen und Halbach O
Year: 2006
Journal: Biol Psychiatry
Title: Regional- and age-dependent reduction in trkB receptor expression in the hippocampus is associated with altered spine morphologies.
Volume: 59
Issue: 9
Pages: 793-800
Publication
First Author: Vyssotski AL
Year: 2002
Journal: Hippocampus
Title: Long-term monitoring of hippocampus-dependent behavior in naturalistic settings: mutant mice lacking neurotrophin receptor TrkB in the forebrain show spatial learning but impaired behavioral flexibility.
Volume: 12
Issue: 1
Pages: 27-38
Publication
First Author: Grishanin RN
Year: 2008
Journal: Mol Cell Neurosci
Title: Retinal TrkB receptors regulate neural development in the inner, but not outer, retina.
Volume: 38
Issue: 3
Pages: 431-43
Publication
First Author: Tan S
Year: 2018
Journal: Proc Natl Acad Sci U S A
Title: Postnatal TrkB ablation in corticolimbic interneurons induces social dominance in male mice.
Volume: 115
Issue: 42
Pages: E9909-E9915
Publication
First Author: Luikart BW
Year: 2003
Journal: Neuroscience
Title: In vivo role of truncated trkb receptors during sensory ganglion neurogenesis.
Volume: 117
Issue: 4
Pages: 847-58
Publication  
First Author: Geibel M
Year: 2014
Journal: Nat Commun
Title: Ablation of TrkB signalling in CCK neurons results in hypercortisolism and obesity.
Volume: 5
Pages: 3427
Publication
First Author: Rohrer B
Year: 1999
Journal: J Neurosci
Title: Role of neurotrophin receptor TrkB in the maturation of rod photoreceptors and establishment of synaptic transmission to the inner retina.
Volume: 19
Issue: 20
Pages: 8919-30
Publication  
First Author: Rohrer B
Year: 2003
Journal: Mol Vis
Title: Retarded outer segment development in TrkB knockout mouse retina organ culture.
Volume: 9
Pages: 18-23
Publication
First Author: Paredes A
Year: 2004
Journal: Dev Biol
Title: TrkB receptors are required for follicular growth and oocyte survival in the mammalian ovary.
Volume: 267
Issue: 2
Pages: 430-49
Publication
First Author: Bosman LW
Year: 2006
Journal: Brain Cell Biol
Title: Requirement of TrkB for synapse elimination in developing cerebellar Purkinje cells.
Volume: 35
Issue: 1
Pages: 87-101
Publication
First Author: Do T
Year: 2007
Journal: J Neurochem
Title: Brain-derived neurotrophic factor regulates the expression of D1 dopamine receptors.
Volume: 100
Issue: 2
Pages: 416-28
Publication  
First Author: Rohrer B
Year: 2001
Journal: Mol Vis
Title: Gene dosage effect of the TrkB receptor on rod physiology and biochemistry in juvenile mouse retina.
Volume: 7
Pages: 288-96