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Search results 1 to 83 out of 83 for Nudt7

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
283927 | NUDT7
Type: gene
Organism: human
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Gene
489703 | NUDT7
Type: gene
Organism: dog, domestic
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Gene
504826 | NUDT7
Type: gene
Organism: cattle
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Gene
415800 | NUDT7
Type: gene
Organism: chicken
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Gene
100329471 | nudt7
Type: gene
Organism: zebrafish
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Gene
715443 | NUDT7
Type: gene
Organism: macaque, rhesus
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Gene
100379717 | nudt7
Type: gene
Organism: frog, western clawed
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Gene
361413 | Nudt7
Type: gene
Organism: rat
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Gene
454256 | NUDT7
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1914778 | Nudt7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
36436558 | J:332648
First Author: Vickers SD
Year: 2023
Journal: J Biol Chem
Title: NUDT7 regulates total hepatic CoA levels and the composition of the intestinal bile acid pool in male mice fed a Western diet.
Volume: 299
Issue: 1
Pages: 102745
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Publication
11415433 | J:70353
First Author: Gasmi L
Year: 2001
Journal: Biochem J
Title: The mouse Nudt7 gene encodes a peroxisomal nudix hydrolase specific for coenzyme A and its derivatives.
Volume: 357
Issue: Pt 1
Pages: 33-8
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Publication
29378847 | J:261972
First Author: Shumar SA
Year: 2018
Journal: J Biol Chem
Title: Nudt19 is a renal CoA diphosphohydrolase with biochemical and regulatory properties that are distinct from the hepatic Nudt7 isoform.
Volume: 293
Issue: 11
Pages: 4134-4148
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Publication
18799520 | J:292520
First Author: Reilly SJ
Year: 2008
Journal: J Biochem
Title: The nudix hydrolase 7 is an Acyl-CoA diphosphatase involved in regulating peroxisomal coenzyme A homeostasis.
Volume: 144
Issue: 5
Pages: 655-63
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Publication
21070968 | J:166846
First Author: Song MG
Year: 2010
Journal: Mol Cell
Title: Multiple mRNA decapping enzymes in mammalian cells.
Volume: 40
Issue: 3
Pages: 423-32
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Publication
30143643 | J:266261
First Author: Song J
Year: 2018
Journal: Nat Commun
Title: Dysregulation of the NUDT7-PGAM1 axis is responsible for chondrocyte death during osteoarthritis pathogenesis.
Volume: 9
Issue: 1
Pages: 3427
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Publication
10922370 | J:68231
First Author: Cartwright JL
Year: 2000
Journal: J Biol Chem
Title: The Saccharomyces cerevisiae PCD1 gene encodes a peroxisomal nudix hydrolase active toward coenzyme A and its derivatives.
Volume: 275
Issue: 42
Pages: 32925-30
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Publication
37908734 | J:342276
First Author: Song J
Year: 2023
Journal: Theranostics
Title: Upregulated FOXM1 stimulates chondrocyte senescence in Acot12(-/-)Nudt7(-/-) double knockout mice.
Volume: 13
Issue: 15
Pages: 5207-5222
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Protein Coding Gene
MGP_CAROLIEiJ_G0031594 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0034158 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0034138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0034065 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0034132 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0033843 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1914778 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0034652 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0033170 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0033816 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0033972 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0033915 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0034061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0033962 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0034670 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0032872 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0033286 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0023192 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0032712 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
12790796 | J:178281
First Author: Abdelraheim SR
Year: 2003
Journal: Biochem J
Title: Mammalian NADH diphosphatases of the Nudix family: cloning and characterization of the human peroxisomal NUDT12 protein.
Volume: 374
Issue: Pt 2
Pages: 329-35
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Publication
18492766 | J:137608
First Author: Wu Y
Year: 2008
Journal: Am J Physiol Endocrinol Metab
Title: Wdnm1-like, a new adipokine with a role in MMP-2 activation.
Volume: 295
Issue: 1
Pages: E205-15
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Publication
- | J:68100
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: RIKEN Data Curation in Mouse Genome Informatics
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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UniProt Feature
UniProt Feature
Begin: 1
Description: Peroxisomal coenzyme A diphosphatase NUDT7
Type: chain
End: 236
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Protein
Q99P30
Organism: Mus musculus/domesticus
Length: 236  
Fragment?: false
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Protein
Q99P30-2
Organism: Mus musculus/domesticus
Length: 260  
Fragment?: false
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Protein
Q99P30-4
Organism: Mus musculus/domesticus
Length: 207  
Fragment?: false
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Protein
Q99P30-3
Organism: Mus musculus/domesticus
Length: 216  
Fragment?: false
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Protein
Q99P30-5
Organism: Mus musculus/domesticus
Length: 171  
Fragment?: false
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Allele
Nudt7<em1Rleo> | MGI:7428334
Name: nudix hydrolase 7; endonuclease-mediated mutation 1, Roberta Leonardi
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
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Publication
32432673 | J:306601
First Author: Sharma S
Year: 2020
Journal: Nucleic Acids Res
Title: Mammalian Nudix proteins cleave nucleotide metabolite caps on RNAs.
Volume: 48
Issue: 12
Pages: 6788-6798
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Publication
12837785 | -
First Author: Kang LW
Year: 2003
Journal: J Bacteriol
Title: Structure of a coenzyme A pyrophosphatase from Deinococcus radiodurans: a member of the Nudix family.
Volume: 185
Issue: 14
Pages: 4110-8
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Publication
23353937 | J:338259
First Author: Song MG
Year: 2013
Journal: RNA
Title: Multiple Nudix family proteins possess mRNA decapping activity.
Volume: 19
Issue: 3
Pages: 390-9
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Protein Domain
IPR045121 | CoAse
Type: Family
Description: Coenzyme A pyrophosphatase (CoAse), a member of the Nudix hydrolase superfamily, functions to catalyse the elimination of oxidized inactive CoA, which can inhibit CoA-utilizing enzymes. The need of CoAses mainly arises under conditions of oxidative stress. CoAse has a conserved Nudix fold and requires a single divalent cation for catalysis. In addition to a signature Nudix motif G[X5]E[X7]REUXEEXGU, where U is Ile, Leu, or Val, CoAse contains an additional motif upstream called the NuCoA motif (LLTXT(SA)X3RX3GX3FPGG) which is postulated to be involved in CoA recognition []. CoA plays a central role in lipid metabolism. It is involved in the initial steps of fatty acid synthesis in the cytosol, in the oxidation of fatty acids and the citric acid cycle in the mitochondria, and in the oxidation of long-chain fatty acids in peroxisomes. CoA has the important role of activating fatty acids for further modification into key biological signalling molecules [, ].Proteins in this family include Nudt7 and Nudt8. Nudt7 mediates the cleavage of CoA, CoA esters and oxidized CoA with similar efficiencies, yielding 3',5'-ADP and the corresponding 4'-phosphopantetheine derivative as products. Preferentially hydrolyzes medium-chain acyl-CoAs and bile acid-CoAs []. This entry also includes yeast Pcd1, which act as peroxisomal pyrophosphatase with specificity for coenzyme A and CoA derivatives [, ].
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Publication
31004344 | J:322382
First Author: Kerr EW
Year: 2019
Journal: FEBS Lett
Title: Nudt8 is a novel CoA diphosphohydrolase that resides in the mitochondria.
Volume: 593
Issue: 11
Pages: 1133-1143
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Protein
Q9CR24
Organism: Mus musculus/domesticus
Length: 210  
Fragment?: false
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Publication
16359314 | -
First Author: Galperin MY
Year: 2006
Journal: Mol Microbiol
Title: House cleaning, a part of good housekeeping.
Volume: 59
Issue: 1
Pages: 5-19
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Publication
16378245 | -
First Author: McLennan AG
Year: 2006
Journal: Cell Mol Life Sci
Title: The Nudix hydrolase superfamily.
Volume: 63
Issue: 2
Pages: 123-43
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Publication
23806337 | J:203468
First Author: Park J
Year: 2013
Journal: Mol Cell
Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.
Volume: 50
Issue: 6
Pages: 919-30
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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