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Search results 1 to 100 out of 2072 for Numb

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Type Details Score
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: rat
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Petersen PH
Year: 2006
Journal: Dev Neurosci
Title: The enigma of the numb-Notch relationship during mammalian embryogenesis.
Volume: 28
Issue: 1-2
Pages: 156-68
Publication
First Author: Petersen PH
Year: 2002
Journal: Nature
Title: Progenitor cell maintenance requires numb and numblike during mouse neurogenesis.
Volume: 419
Issue: 6910
Pages: 929-34
Publication
First Author: Zhong W
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Mouse numb is an essential gene involved in cortical neurogenesis.
Volume: 97
Issue: 12
Pages: 6844-9
Publication
First Author: Klein AL
Year: 2004
Journal: Dev Biol
Title: Murine numb regulates granule cell maturation in the cerebellum.
Volume: 266
Issue: 1
Pages: 161-77
Publication
First Author: Rice DS
Year: 2001
Journal: Mol Cell Neurosci
Title: The Lnx family proteins function as molecular scaffolds for Numb family proteins.
Volume: 18
Issue: 5
Pages: 525-40
Publication
First Author: Zhong W
Year: 1996
Journal: Neuron
Title: Asymmetric localization of a mammalian numb homolog during mouse cortical neurogenesis.
Volume: 17
Issue: 1
Pages: 43-53
Publication  
First Author: Wang N
Year: 2019
Journal: Neurosci Lett
Title: Numb deficiency causes impaired trafficking of mGlu5 in neurons and autistic-like behaviors.
Volume: 707
Pages: 134291
Publication
First Author: Wilson A
Year: 2007
Journal: J Immunol
Title: Normal hemopoiesis and lymphopoiesis in the combined absence of numb and numblike.
Volume: 178
Issue: 11
Pages: 6746-51
Publication
First Author: Petersen PH
Year: 2004
Journal: Nat Neurosci
Title: Continuing role for mouse Numb and Numbl in maintaining progenitor cells during cortical neurogenesis.
Volume: 7
Issue: 8
Pages: 803-11
Publication
First Author: Zhang Y
Year: 2016
Journal: FASEB J
Title: Numb and Numbl act to determine mammary myoepithelial cell fate, maintain epithelial identity, and support lactogenesis.
Volume: 30
Issue: 10
Pages: 3474-3488
Publication
First Author: van Lessen M
Year: 2015
Journal: Arterioscler Thromb Vasc Biol
Title: Regulation of vascular endothelial growth factor receptor function in angiogenesis by numb and numb-like.
Volume: 35
Issue: 8
Pages: 1815-25
Publication  
First Author: Le Roux I
Year: 2015
Journal: Nat Commun
Title: Numb is required to prevent p53-dependent senescence following skeletal muscle injury.
Volume: 6
Pages: 8528
Publication
First Author: Abdi K
Year: 2019
Journal: Cell Rep
Title: EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation.
Volume: 28
Issue: 8
Pages: 2012-2022.e4
Publication
First Author: Dho SE
Year: 1999
Journal: J Biol Chem
Title: Characterization of four mammalian numb protein isoforms. Identification of cytoplasmic and membrane-associated variants of the phosphotyrosine binding domain.
Volume: 274
Issue: 46
Pages: 33097-104
Publication  
First Author: Li H
Year: 2013
Journal: Biomed Res Int
Title: Expression and function of NUMB in odontogenesis.
Volume: 2013
Pages: 182965
Publication
First Author: Zhou P
Year: 2011
Journal: Dev Cell
Title: Numb links extracellular cues to intracellular polarity machinery to promote chemotaxis.
Volume: 20
Issue: 5
Pages: 610-22
Publication
First Author: Liu L
Year: 2011
Journal: Biochem Biophys Res Commun
Title: Numblike and Numb differentially affect p53 and Sonic Hedgehog signaling.
Volume: 413
Issue: 3
Pages: 426-31
Publication
First Author: Martin-Blanco N
Year: 2016
Journal: Int Immunol
Title: CD3ε recruits Numb to promote TCR degradation.
Volume: 28
Issue: 3
Pages: 127-37
Publication
First Author: Zhou L
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Numb deficiency in cerebellar Purkinje cells impairs synaptic expression of metabotropic glutamate receptor and motor coordination.
Volume: 112
Issue: 50
Pages: 15474-9
Publication
First Author: Bani-Yaghoub M
Year: 2007
Journal: Dev Dyn
Title: A switch in numb isoforms is a critical step in cortical development.
Volume: 236
Issue: 3
Pages: 696-705
Publication
First Author: Nie J
Year: 2002
Journal: EMBO J
Title: LNX functions as a RING type E3 ubiquitin ligase that targets the cell fate determinant Numb for ubiquitin-dependent degradation.
Volume: 21
Issue: 1-2
Pages: 93-102
Publication
First Author: Aguado R
Year: 2010
Journal: Blood
Title: The endocytic adaptor Numb regulates thymus size by modulating pre-TCR signaling during asymmetric division.
Volume: 116
Issue: 10
Pages: 1705-14
GXD Expression      
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6190984
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - Numb
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6190984
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - Numb
Detected: false
Specimen Num: 3
GXD Expression    
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190984
Age: postnatal day 4
Specimen Label: Table S2 - P4 - Numb
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190984
Age: postnatal day 14
Specimen Label: Table S2 - P14 - Numb
Detected: true
Specimen Num: 6
GXD Expression      
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6190984
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - Numb
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6190984
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - Numb
Detected: false
Specimen Num: 4
GXD Expression    
Probe: MGI:6179442
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6190984
Age: postnatal day 28
Specimen Label: Table S2 - P28 - Numb
Detected: true
Specimen Num: 7
Publication
First Author: Dho SE
Year: 1998
Journal: J Biol Chem
Title: The mammalian numb phosphotyrosine-binding domain. Characterization of binding specificity and identification of a novel PDZ domain-containing numb binding protein, LNX.
Volume: 273
Issue: 15
Pages: 9179-87
Publication
First Author: Di Marcotullio L
Year: 2011
Journal: Oncogene
Title: Numb activates the E3 ligase Itch to control Gli1 function through a novel degradation signal.
Volume: 30
Issue: 1
Pages: 65-76
Publication
First Author: Zhu F
Year: 2021
Journal: Biochim Biophys Acta Mol Basis Dis
Title: Tubular Numb promotes renal interstitial fibrosis via modulating HIF-1α protein stability.
Volume: 1867
Issue: 5
Pages: 166081
Publication
First Author: Shu Y
Year: 2021
Journal: Cell Death Dis
Title: Loss of Numb promotes hepatic progenitor expansion and intrahepatic cholangiocarcinoma by enhancing Notch signaling.
Volume: 12
Issue: 11
Pages: 966
Publication
First Author: McGill MA
Year: 2009
Journal: J Biol Chem
Title: Numb regulates post-endocytic trafficking and degradation of Notch1.
Volume: 284
Issue: 39
Pages: 26427-38
Publication
First Author: Ramamurthy V
Year: 2014
Journal: J Neurosci
Title: Numb regulates the polarized delivery of cyclic nucleotide-gated ion channels in rod photoreceptor cilia.
Volume: 34
Issue: 42
Pages: 13976-87
Publication
First Author: French MB
Year: 2002
Journal: J Immunol
Title: Transgenic expression of numb inhibits notch signaling in immature thymocytes but does not alter T cell fate specification.
Volume: 168
Issue: 7
Pages: 3173-80
Publication
First Author: Shen Q
Year: 2002
Journal: Development
Title: Asymmetric Numb distribution is critical for asymmetric cell division of mouse cerebral cortical stem cells and neuroblasts.
Volume: 129
Issue: 20
Pages: 4843-53
Publication
First Author: Greer RL
Year: 2013
Journal: Gastroenterology
Title: Numb regulates acinar cell dedifferentiation and survival during pancreatic damage and acinar-to-ductal metaplasia.
Volume: 145
Issue: 5
Pages: 1088-1097.e8
Publication
First Author: Yang Y
Year: 2013
Journal: Exp Cell Res
Title: Numb modulates the paracellular permeability of intestinal epithelial cells through regulating apical junctional complex assembly and myosin light chain phosphorylation.
Volume: 319
Issue: 20
Pages: 3214-25
Publication
First Author: Li PS
Year: 2014
Journal: Nat Med
Title: The clathrin adaptor Numb regulates intestinal cholesterol absorption through dynamic interaction with NPC1L1.
Volume: 20
Issue: 1
Pages: 80-6
Publication
First Author: Anderson AC
Year: 2005
Journal: J Immunol
Title: The Notch regulator Numb links the Notch and TCR signaling pathways.
Volume: 174
Issue: 2
Pages: 890-7
Publication
First Author: Huang EJ
Year: 2005
Journal: Genes Dev
Title: Targeted deletion of numb and numblike in sensory neurons reveals their essential functions in axon arborization.
Volume: 19
Issue: 1
Pages: 138-51
Publication
First Author: Zilian O
Year: 2001
Journal: Curr Biol
Title: Multiple roles of mouse Numb in tuning developmental cell fates.
Volume: 11
Issue: 7
Pages: 494-501
Publication  
First Author: Shenje LT
Year: 2014
Journal: Elife
Title: Precardiac deletion of Numb and Numblike reveals renewal of cardiac progenitors.
Volume: 3
Pages: e02164
Publication
First Author: Kim KK
Year: 2013
Journal: J Cell Biol
Title: Rbfox3-regulated alternative splicing of Numb promotes neuronal differentiation during development.
Volume: 200
Issue: 4
Pages: 443-58
Publication
First Author: Kuo CT
Year: 2006
Journal: Cell
Title: Postnatal deletion of Numb/Numblike reveals repair and remodeling capacity in the subventricular neurogenic niche.
Volume: 127
Issue: 6
Pages: 1253-64
Publication
First Author: Ferent J
Year: 2019
Journal: Neuron
Title: Boc Acts via Numb as a Shh-Dependent Endocytic Platform for Ptch1 Internalization and Shh-Mediated Axon Guidance.
Volume: 102
Issue: 6
Pages: 1157-1171.e5
Publication
First Author: Gibbs BC
Year: 2018
Journal: Biochem Biophys Res Commun
Title: β1-integrin is a cell-autonomous factor mediating the Numb pathway for cardiac progenitor maintenance.
Volume: 500
Issue: 2
Pages: 256-260
Publication
First Author: Lacomme M
Year: 2022
Journal: Sci Adv
Title: Numb regulates Tau levels and prevents neurodegeneration in tauopathy mouse models.
Volume: 8
Issue: 42
Pages: eabm4295
Publication
First Author: Kechad A
Year: 2012
Journal: J Neurosci
Title: Numb is required for the production of terminal asymmetric cell divisions in the developing mouse retina.
Volume: 32
Issue: 48
Pages: 17197-17210
Publication
First Author: Li HS
Year: 2003
Journal: Neuron
Title: Inactivation of Numb and Numblike in embryonic dorsal forebrain impairs neurogenesis and disrupts cortical morphogenesis.
Volume: 40
Issue: 6
Pages: 1105-18
Publication
First Author: Rasin MR
Year: 2007
Journal: Nat Neurosci
Title: Numb and Numbl are required for maintenance of cadherin-based adhesion and polarity of neural progenitors.
Volume: 10
Issue: 7
Pages: 819-27
Publication
First Author: Lin YT
Year: 2017
Journal: Development
Title: Numb regulates somatic cell lineage commitment during early gonadogenesis in mice.
Volume: 144
Issue: 9
Pages: 1607-1618
Publication
First Author: Cheng X
Year: 2008
Journal: Development
Title: Numb mediates the interaction between Wnt and Notch to modulate primitive erythropoietic specification from the hemangioblast.
Volume: 135
Issue: 20
Pages: 3447-58
Publication  
First Author: Ianni A
Year: 2021
Journal: Front Cell Dev Biol
Title: Depletion of Numb and Numblike in Murine Lung Epithelial Cells Ameliorates Bleomycin-Induced Lung Fibrosis by Inhibiting the β-Catenin Signaling Pathway.
Volume: 9
Pages: 639162
Publication  
First Author: Miao L
Year: 2021
Journal: Cells
Title: The Spatiotemporal Expression of Notch1 and Numb and Their Functional Interaction during Cardiac Morphogenesis.
Volume: 10
Issue: 9
Publication
First Author: Tosoni D
Year: 2015
Journal: J Cell Biol
Title: The Numb/p53 circuitry couples replicative self-renewal and tumor suppression in mammary epithelial cells.
Volume: 211
Issue: 4
Pages: 845-62
Publication
First Author: Di Marcotullio L
Year: 2006
Journal: Nat Cell Biol
Title: Numb is a suppressor of Hedgehog signalling and targets Gli1 for Itch-dependent ubiquitination.
Volume: 8
Issue: 12
Pages: 1415-23
Publication
First Author: Moran TB
Year: 2011
Journal: Mol Endocrinol
Title: Numb deletion in POMC-expressing cells impairs pituitary intermediate lobe cell adhesion, progenitor cell localization, and neuro-intermediate lobe boundary formation.
Volume: 25
Issue: 1
Pages: 117-27
Publication
First Author: Roncarati R
Year: 2002
Journal: Proc Natl Acad Sci U S A
Title: The gamma-secretase-generated intracellular domain of beta-amyloid precursor protein binds Numb and inhibits Notch signaling.
Volume: 99
Issue: 10
Pages: 7102-7
Publication      
First Author: Lenihan JA
Year: 2016
Journal: Mol Neurobiol
Title: Decreased Anxiety-Related Behaviour but Apparently Unperturbed NUMB Function in Ligand of NUMB Protein-X (LNX) 1/2 Double Knockout Mice.
Publication
First Author: Miao L
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Cardiomyocyte orientation modulated by the Numb family proteins-N-cadherin axis is essential for ventricular wall morphogenesis.
Volume: 116
Issue: 31
Pages: 15560-15569
Publication
First Author: Su JF
Year: 2016
Journal: J Cell Sci
Title: Numb directs the subcellular localization of EAAT3 through binding the YxNxxF motif.
Volume: 129
Issue: 16
Pages: 3104-14
Publication
First Author: Hirai M
Year: 2017
Journal: J Clin Invest
Title: Adaptor proteins NUMB and NUMBL promote cell cycle withdrawal by targeting ERBB2 for degradation.
Volume: 127
Issue: 2
Pages: 569-582
Publication
First Author: Zhao C
Year: 2014
Journal: Development
Title: Numb family proteins are essential for cardiac morphogenesis and progenitor differentiation.
Volume: 141
Issue: 2
Pages: 281-95
Publication
First Author: Jory A
Year: 2009
Journal: Stem Cells
Title: Numb promotes an increase in skeletal muscle progenitor cells in the embryonic somite.
Volume: 27
Issue: 11
Pages: 2769-80
Publication
First Author: Tarn WY
Year: 2016
Journal: Mol Biol Cell
Title: RBM4 promotes neuronal differentiation and neurite outgrowth by modulating Numb isoform expression.
Volume: 27
Issue: 10
Pages: 1676-83
Publication
First Author: El-Hashash AH
Year: 2012
Journal: J Histochem Cytochem
Title: Numb expression and asymmetric versus symmetric cell division in distal embryonic lung epithelium.
Volume: 60
Issue: 9
Pages: 675-82
Gene
Type: gene
Organism: human
Publication  
First Author: Liu K
Year: 2015
Journal: Neurosci Lett
Title: Gαs regulates asymmetric cell division of cortical progenitors by controlling Numb mediated Notch signaling suppression.
Volume: 597
Pages: 97-103
Publication
First Author: Kuang W
Year: 2009
Journal: Biochem Biophys Res Commun
Title: Cyclic stretch induced miR-146a upregulation delays C2C12 myogenic differentiation through inhibition of Numb.
Volume: 378
Issue: 2
Pages: 259-63
Publication
First Author: Krieger JR
Year: 2013
Journal: Mol Cell Proteomics
Title: Identification and selected reaction monitoring (SRM) quantification of endocytosis factors associated with Numb.
Volume: 12
Issue: 2
Pages: 499-514
Publication
First Author: George RM
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Numb-deficient satellite cells have regeneration and proliferation defects.
Volume: 110
Issue: 46
Pages: 18549-54
Publication
First Author: Chapman G
Year: 2006
Journal: J Cell Biol
Title: High levels of Notch signaling down-regulate Numb and Numblike.
Volume: 175
Issue: 4
Pages: 535-40
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory