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Search results 1 to 100 out of 101 for Nup214

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1.061s

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
key_1584459 | Nup214
Type: gene
Organism: Not Specified
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Gene
8021 | NUP214
Type: gene
Organism: human
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Gene
100145463 | nup214
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR044694 | NUP214
Type: Family
Description: Nuclear pore complex protein NUP214 (also known as Protein LONO1 and Protein EMBRYO DEFECTIVE 1011) is a component of the nuclear pore complex in Arabidopsis, required for mature mRNA export from the nucleus to the cytoplasm, essential for normal embryogenesis and seed viability []. It is important during early embryogenesis, being involved in the first asymmetrical cell division of the zygote and regulates the number and planes of cell divisions required for generating the normal embryo proper and suspensor, apical-basal axis, cotyledons and meristem [, ].
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Gene
296634 | Nup214
Type: gene
Organism: rat
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Gene
608534 | NUP214
Type: gene
Organism: dog, domestic
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Gene
464807 | NUP214
Type: gene
Organism: chimpanzee
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Gene
784219 | NUP214
Type: gene
Organism: cattle
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Gene
427760 | NUP214
Type: gene
Organism: chicken
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Gene
100529857 | nup214
Type: gene
Organism: zebrafish
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Gene
722421 | NUP214
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1095411 | Nup214
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
22898497 | -
First Author: Braud C
Year: 2012
Journal: Plant Physiol
Title: LONO1 encoding a nucleoporin is required for embryogenesis and seed viability in Arabidopsis.
Volume: 160
Issue: 2
Pages: 823-36
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Gene
139355201 | NUP214-AS1
Type: gene
Organism: human
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Publication
15266054 | -
First Author: Tzafrir I
Year: 2004
Journal: Plant Physiol
Title: Identification of genes required for embryo development in Arabidopsis.
Volume: 135
Issue: 3
Pages: 1206-20
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Publication
27114368 | J:236184
First Author: Saito S
Year: 2016
Journal: Mol Cell Biol
Title: Leukemia-Associated Nup214 Fusion Proteins Disturb the XPO1-Mediated Nuclear-Cytoplasmic Transport Pathway and Thereby the NF-κB Signaling Pathway.
Volume: 36
Issue: 13
Pages: 1820-35
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Gene
108491830 | LOC108491830
Type: gene
Organism: human
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Publication
8896451 | J:36515
First Author: van Deursen J
Year: 1996
Journal: EMBO J
Title: G2 arrest and impaired nucleocytoplasmic transport in mouse embryos lacking the proto-oncogene CAN/Nup214.
Volume: 15
Issue: 20
Pages: 5574-83
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Protein
Q80U93
Organism: Mus musculus/domesticus
Length: 2085  
Fragment?: false
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Protein Coding Gene
MGP_CAROLIEiJ_G0023421 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0025594 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0025572 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0025541 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0025568 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0025329 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1095411 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026013 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0024791 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0025306 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0025439 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0025402 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0025525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0025432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0026071 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0024538 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0024859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024878 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0024338 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
     
Probe: MGI:5642139
Assay Type: Western blot
Annotation Date: 2015-06-30
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5642174
Age: postnatal adult
Specimen Label: None
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
 
Probe: MGI:3844006
Assay Type: RNA in situ
Annotation Date: 2009-05-13
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1609217
Pattern: Regionally restricted
Stage: TS17
Assay Id: MGI:3844046
Age: embryonic day 10.5
Note: Expression was low in the dorsal spinal cord.
Specimen Label: Table 1
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4359249
Assay Type: Immunohistochemistry
Annotation Date: 2009-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4359466
Age: embryonic day 9.5
Specimen Label: S2 CAN/Nup214 wt
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:4359249
Assay Type: Immunohistochemistry
Annotation Date: 2009-09-28
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1646915
Pattern: Not Specified
Stage: TS15
Assay Id: MGI:4359466
Age: embryonic day 9.5
Note: Expression was detected as in wild type.
Specimen Label: S2 CAN/Nup214 merm
Detected: true
Specimen Num: 2
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Publication
14697343 | J:87860
First Author: Olsson M
Year: 2004
Journal: Exp Cell Res
Title: Limited expression of nuclear pore membrane glycoprotein 210 in cell lines and tissues suggests cell-type specific nuclear pores in metazoans.
Volume: 292
Issue: 2
Pages: 359-70
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Publication
19581287 | J:152609
First Author: Echeverría PC
Year: 2009
Journal: Mol Cell Biol
Title: Nuclear import of the glucocorticoid receptor-hsp90 complex through the nuclear pore complex is mediated by its interaction with Nup62 and importin beta.
Volume: 29
Issue: 17
Pages: 4788-97
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Publication
12791264 | J:320054
First Author: Suntharalingam M
Year: 2003
Journal: Dev Cell
Title: Peering through the pore: nuclear pore complex structure, assembly, and function.
Volume: 4
Issue: 6
Pages: 775-89
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Publication
8211130 | J:14384
First Author: Copeland NG
Year: 1993
Journal: Science
Title: A genetic linkage map of the mouse: current applications and future prospects.
Volume: 262
Issue: 5130
Pages: 57-66
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Publication
19026994 | J:147809
 
First Author: Masuda T
Year: 2009
Journal: Brain Res
Title: Laser capture microdissection and cDNA array analysis for identification of mouse KIAA/FLJ genes differentially expressed in the embryonic dorsal spinal cord.
Volume: 1249
Pages: 61-7
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Publication
- | J:38089
First Author: Pilz A
Year: 1996
Journal: Mouse Genome
Title: High resolution genetic linkage analysis of mouse Chromosome 2 in the region of homology with human Chromosome 9
Volume: 94
Issue: 4
Pages: 877-9
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Publication
18539113 | J:137199
First Author: Lupu F
Year: 2008
Journal: Dev Cell
Title: Nuclear pore composition regulates neural stem/progenitor cell differentiation in the mouse embryo.
Volume: 14
Issue: 6
Pages: 831-42
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Publication
7774911 | J:22833
First Author: Pilz A
Year: 1995
Journal: Genomics
Title: Comparative mapping of 50 human chromosome 9 loci in the laboratory mouse.
Volume: 25
Issue: 1
Pages: 139-49
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:77000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: MGC Data curation in Mouse Genome Informatics
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Publication
- | J:73065
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
12904583 | J:85162
First Author: Hansen J
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome.
Volume: 100
Issue: 17
Pages: 9918-22
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Publication
17967808 | J:152068
First Author: Friedel RH
Year: 2007
Journal: Brief Funct Genomic Proteomic
Title: EUCOMM--the European conditional mouse mutagenesis program.
Volume: 6
Issue: 3
Pages: 180-5
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Publication
12520002 | J:91812
First Author: Stryke D
Year: 2003
Journal: Nucleic Acids Res
Title: BayGenomics: a resource of insertional mutations in mouse embryonic stem cells.
Volume: 31
Issue: 1
Pages: 278-81
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Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
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Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
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Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Protein
Q8CHS9
Organism: Mus musculus/domesticus
Length: 1529  
Fragment?: false
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UniProt Feature
UniProt Feature
Begin: 2
Description: Nuclear pore complex protein Nup214
Type: chain
End: 2085
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Protein
A2ATN3
Organism: Mus musculus/domesticus
Length: 581  
Fragment?: true
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Protein
A0A0A6YW83
Organism: Mus musculus/domesticus
Length: 98  
Fragment?: true
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Protein
A0A0A6YY32
Organism: Mus musculus/domesticus
Length: 147  
Fragment?: true
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Allele
Gt(ROSA)26Sor<tm1(Nup214/Abl1)Cool> | MGI:6197969
Name: gene trap ROSA 26, Philippe Soriano; targeted mutation 1, Jan Cools
Allele Type: Targeted
Attribute String: Conditional ready, Inserted expressed sequence, Reporter
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Allele
Tg(Ly6a-SET/NUP214)2969Gcg | MGI:3822861
Name: transgene insertion 2969, Gerard C Grosveld
Allele Type: Transgenic
Attribute String: Inserted expressed sequence
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Publication
26489467 | -
First Author: Port SA
Year: 2015
Journal: Cell Rep
Title: Structural and Functional Characterization of CRM1-Nup214 Interactions Reveals Multiple FG-Binding Sites Involved in Nuclear Export.
Volume: 13
Issue: 4
Pages: 690-702
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Protein Domain
IPR041553 | Nup214_FG
Type: Domain
Description: CRM1 is the major nuclear export receptor. During translocation through the nuclear pore, transport complexes transiently interact with phenylalanine-glycine (FG) repeats of multiple nucleoporins. On the cytoplasmic side of the nuclear pore, CRM1 tightly interacts with the nucleoporin Nup214. Nup214 binds to N- and C-terminal regions of CRM1, thereby clamping CRM1 in a closed conformation andstabilizing the export complex. This entry represents an FG repeat region within the C terminus of Nup214 which is required for its interaction with CRM1 [].
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Publication
17569777 | J:142938
First Author: Ozbek U
Year: 2007
Journal: Am J Pathol
Title: SET-CAN, the product of the t(9;9) in acute undifferentiated leukemia, causes expansion of early hematopoietic progenitors and hyperproliferation of stomach mucosa in transgenic mice.
Volume: 171
Issue: 2
Pages: 654-66
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Genotype
Genotype
Symbol: Tg(Ly6a-SET/NUP214)2969Gcg/?
Background: involves: FVB/NJ
Zygosity: ot
Has Mutant Allele: true
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Publication
25765544 | J:224953
First Author: Sandén C
Year: 2015
Journal: Leukemia
Title: The DEK oncoprotein and its emerging roles in gene regulation.
Volume: 29
Issue: 8
Pages: 1632-6
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Publication
33755722 | J:322182
 
First Author: Chen Z
Year: 2021
Journal: J Exp Med
Title: Nuclear DEK preserves hematopoietic stem cells potential via NCoR1/HDAC3-Akt1/2-mTOR axis.
Volume: 218
Issue: 5
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Publication
30107177 | J:264234
First Author: Vanden Bempt M
Year: 2018
Journal: Cancer Cell
Title: Cooperative Enhancer Activation by TLX1 and STAT5 Drives Development of NUP214-ABL1/TLX1-Positive T Cell Acute Lymphoblastic Leukemia.
Volume: 34
Issue: 2
Pages: 271-285.e7
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Publication
31622281 | J:285270
 
First Author: Yin M
Year: 2019
Journal: JCI Insight
Title: A unique mutator phenotype reveals complementary oncogenic lesions leading to acute leukemia.
Volume: 4
Issue: 23
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Publication
12693553 | J:83413
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: II. The complete nucleotide sequences of 400 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 1
Pages: 35-48
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Publication
19144319 | J:143718
First Author: Trost M
Year: 2009
Journal: Immunity
Title: The phagosomal proteome in interferon-gamma-activated macrophages.
Volume: 30
Issue: 1
Pages: 143-54
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Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
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Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
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