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Search results 1 to 77 out of 77 for Nup58

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: zebrafish
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Suntharalingam M
Year: 2003
Journal: Dev Cell
Title: Peering through the pore: nuclear pore complex structure, assembly, and function.
Volume: 4
Issue: 6
Pages: 775-89
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_04
Specimen Label: euxassay_003663_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_05
Specimen Label: euxassay_003663_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_06
Specimen Label: euxassay_003663_06
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_07
Specimen Label: euxassay_003663_07
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_21
Specimen Label: euxassay_003663_21
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_22
Specimen Label: euxassay_003663_22
Detected: true
Specimen Num: 6
Publication
First Author: Leppek K
Year: 2020
Journal: Mol Cell
Title: Gene- and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments.
Volume: 80
Issue: 6
Pages: 980-995.e13
Publication
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
Publication        
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
Publication
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
Publication        
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
Publication        
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
Publication
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
Publication        
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
Publication
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication      
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Sharma A
Year: 2015
Journal: J Biol Chem
Title: Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution.
Volume: 290
Issue: 30
Pages: 18370-8
Publication
First Author: Solmaz SR
Year: 2011
Journal: Cell
Title: Molecular architecture of the transport channel of the nuclear pore complex.
Volume: 147
Issue: 3
Pages: 590-602
Publication
First Author: Bednenko J
Year: 2003
Journal: Traffic
Title: Nucleocytoplasmic transport: navigating the channel.
Volume: 4
Issue: 3
Pages: 127-35
Protein Domain
Type: Domain
Description: The mammalian nuclear pore complex (NPC) conducts nucleocytoplasmic transport and contains multiple copies of nucleoporins (nups). This is the C-terminal interacting domain found on Nup54. Nup45 is a splice variant of Nup58 with an identical α-helical region. Nup54 along with Nup62 and Nup58 are essential for nuclear transport. The C-terminal part of the α-helical region of Nup54 interacts with a C-terminal part of the α-helical region of Nup58. Interestingly, this region appears in two distinct conformations: a single helix and a helix-loop-helix, termed 'straight' and 'bent'. Whereas the straight conformer consists of a 34 residues long alpha helix (residues 460-493), the bent conformer is composed of two alpha helices, each 13 residues long, connected by a central loop (N helix, residues 460-472; C helix, residues 477-489) [].
Protein Domain
Type: Domain
Description: This entry represents the α-helical domain of human Nup54. Nup54 interacts with Nup58 via the C-terminal part of this domain and Nup62 via the N-terminal part to form the nucleoporin complex []. Nup54, Nup58 and Nup62 all have similar affinities for importin-beta. It seems likely that they are the only FG-repeat nucleoporins of the central channel, and as such they would form a zone of equal affinity spanning the central channel. The diffusion of importin-beta import complexes through the central channel may be a stochastic process as the affinities are similar, whereas movement from cytoplasmic fibrils to the central channel and from the central channel to the nuclear basket would be facilitated by the subtle differences in affinity between them [, ]. In yeast, Nup54 is known as Nup57.
Protein
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 587  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 581  
Fragment?: true
Publication
First Author: Hu T
Year: 1998
Journal: Gene
Title: cDNA cloning and analysis of the expression of nucleoporin p45.
Volume: 221
Issue: 2
Pages: 245-53
Protein Domain
Type: Family
Description: Nucleoporin proteins p58 and p45 are components of the p62 complex, an assembly of four O-linked glycoproteins localised near the central gated channel of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane []. The p45 and p58 isoforms are generated by mRNA alternative splicing []. This entry also includes Nup58 protein from Drosophila melanogaster and Nup45 from Schizosaccharomyces pombe [].
Publication
First Author: Hu T
Year: 1996
Journal: J Cell Biol
Title: Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.
Volume: 134
Issue: 3
Pages: 589-601
Publication
First Author: Chen XQ
Year: 2004
Journal: Yeast
Title: Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.
Volume: 21
Issue: 6
Pages: 495-509