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Search results 1 to 80 out of 80 for Nup58

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Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
9818 | NUP58
Type: gene
Organism: human
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Gene
595038 | nup58
Type: gene
Organism: frog, western clawed
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Gene
245922 | Nup58
Type: gene
Organism: rat
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Gene
477334 | NUP58
Type: gene
Organism: dog, domestic
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Gene
452497 | NUP58
Type: gene
Organism: chimpanzee
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Gene
614694 | NUP58
Type: gene
Organism: cattle
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Gene
418937 | NUP58
Type: gene
Organism: chicken
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Gene
406510 | nup58
Type: gene
Organism: zebrafish
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Gene
709215 | NUP58
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1919094 | Nup58
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12791264 | J:320054
First Author: Suntharalingam M
Year: 2003
Journal: Dev Cell
Title: Peering through the pore: nuclear pore complex structure, assembly, and function.
Volume: 4
Issue: 6
Pages: 775-89
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Protein Coding Gene
MGP_CAROLIEiJ_G0019373 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0021430 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0021389 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0021364 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0021394 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0021172 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1919094 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0021833 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0020688 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0021139 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0021262 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0021240 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0021336 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0021269 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0021856 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0020432 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0020741 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0030391 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0020265 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_04
Specimen Label: euxassay_003663_04
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_05
Specimen Label: euxassay_003663_05
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_06
Specimen Label: euxassay_003663_06
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_07
Specimen Label: euxassay_003663_07
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_21
Specimen Label: euxassay_003663_21
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
 
Probe: MGI:1465010
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:1797223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4826835
Age: embryonic day 14.5
Image: euxassay_003663_22
Specimen Label: euxassay_003663_22
Detected: true
Specimen Num: 6
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Publication
33202249 | J:300170
First Author: Leppek K
Year: 2020
Journal: Mol Cell
Title: Gene- and Species-Specific Hox mRNA Translation by Ribosome Expansion Segments.
Volume: 80
Issue: 6
Pages: 980-995.e13
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Publication
15102471 | J:114108
First Author: Papin J
Year: 2004
Journal: Curr Opin Biotechnol
Title: Bioinformatics and cellular signaling.
Volume: 15
Issue: 1
Pages: 78-81
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Publication
- | J:193309
       
First Author: Mouse Genome Informatics Scientfic Curators
Year: 2013
Title: Curated associations of genes in MGI and UniProt sequence records
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Publication
14621295 | J:86686
First Author: Okazaki N
Year: 2003
Journal: DNA Res
Title: Prediction of the coding sequences of mouse homologues of KIAA gene: III. the complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.
Volume: 10
Issue: 4
Pages: 167-80
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Publication
- | J:342607
       
First Author: Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom
Year: 2023
Title: Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:155856
       
First Author: The Gene Ontology Consortium
Year: 2014
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs
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Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
26025361 | -
First Author: Sharma A
Year: 2015
Journal: J Biol Chem
Title: Ordered Regions of Channel Nucleoporins Nup62, Nup54, and Nup58 Form Dynamic Complexes in Solution.
Volume: 290
Issue: 30
Pages: 18370-8
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Publication
22036567 | -
First Author: Solmaz SR
Year: 2011
Journal: Cell
Title: Molecular architecture of the transport channel of the nuclear pore complex.
Volume: 147
Issue: 3
Pages: 590-602
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Publication
12656985 | -
First Author: Bednenko J
Year: 2003
Journal: Traffic
Title: Nucleocytoplasmic transport: navigating the channel.
Volume: 4
Issue: 3
Pages: 127-35
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Protein Domain
IPR040985 | Nup54_C
Type: Domain
Description: The mammalian nuclear pore complex (NPC) conducts nucleocytoplasmic transport and contains multiple copies of nucleoporins (nups). This is the C-terminal interacting domain found on Nup54. Nup45 is a splice variant of Nup58 with an identical α-helical region. Nup54 along with Nup62 and Nup58 are essential for nuclear transport. The C-terminal part of the α-helical region of Nup54 interacts with a C-terminal part of the α-helical region of Nup58. Interestingly, this region appears in two distinct conformations: a single helix and a helix-loop-helix, termed 'straight' and 'bent'. Whereas the straight conformer consists of a 34 residues long alpha helix (residues 460-493), the bent conformer is composed of two alpha helices, each 13 residues long, connected by a central loop (N helix, residues 460-472; C helix, residues 477-489) [].
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Protein Domain
IPR025712 | Nup54_alpha-helical_dom
Type: Domain
Description: This entry represents the α-helical domain of human Nup54. Nup54 interacts with Nup58 via the C-terminal part of this domain and Nup62 via the N-terminal part to form the nucleoporin complex []. Nup54, Nup58 and Nup62 all have similar affinities for importin-beta. It seems likely that they are the only FG-repeat nucleoporins of the central channel, and as such they would form a zone of equal affinity spanning the central channel. The diffusion of importin-beta import complexes through the central channel may be a stochastic process as the affinities are similar, whereas movement from cytoplasmic fibrils to the central channel and from the central channel to the nuclear basket would be facilitated by the subtle differences in affinity between them [, ]. In yeast, Nup54 is known as Nup57.
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Protein
Q8BTS4
Organism: Mus musculus/domesticus
Length: 510  
Fragment?: false
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Protein
Q8R332
Organism: Mus musculus/domesticus
Length: 587  
Fragment?: false
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Protein
Q6ZQC2
Organism: Mus musculus/domesticus
Length: 544  
Fragment?: true
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Protein
Q3UZQ6
Organism: Mus musculus/domesticus
Length: 581  
Fragment?: true
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Publication
9795236 | -
First Author: Hu T
Year: 1998
Journal: Gene
Title: cDNA cloning and analysis of the expression of nucleoporin p45.
Volume: 221
Issue: 2
Pages: 245-53
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Protein Domain
IPR024882 | Nucleoporin_p58/p45
Type: Family
Description: Nucleoporin proteins p58 and p45 are components of the p62 complex, an assembly of four O-linked glycoproteins localised near the central gated channel of the nuclear pore complex, a complex required for the trafficking across the nuclear membrane []. The p45 and p58 isoforms are generated by mRNA alternative splicing []. This entry also includes Nup58 protein from Drosophila melanogaster and Nup45 from Schizosaccharomyces pombe [].
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Publication
8707840 | -
First Author: Hu T
Year: 1996
Journal: J Cell Biol
Title: Molecular and functional characterization of the p62 complex, an assembly of nuclear pore complex glycoproteins.
Volume: 134
Issue: 3
Pages: 589-601
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Publication
15116432 | -
First Author: Chen XQ
Year: 2004
Journal: Yeast
Title: Identification of genes encoding putative nucleoporins and transport factors in the fission yeast Schizosaccharomyces pombe: a deletion analysis.
Volume: 21
Issue: 6
Pages: 495-509
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