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Search results 1 to 89 out of 89 for Nxf3

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Categories

Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
56000 | NXF3
Type: gene
Organism: human
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Gene
465774 | NXF3
Type: gene
Organism: chimpanzee
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Gene
491441 | NXF3
Type: gene
Organism: dog, domestic
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Gene
523530 | NXF3
Type: gene
Organism: cattle
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Gene
695351 | NXF3
Type: gene
Organism: macaque, rhesus
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Gene
302591 | Nxf3
Type: gene
Organism: rat
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Protein Domain
IPR030216 | NXF3
Type: Family
Description: Nuclear RNA export factor 3 (NXF3) is a member of the nuclear RNA export factor (NXF) family of proteins, which plays a role in mediating the export of cellular mRNA from the nucleus to the cytoplasm for translation. Like NXF1 and NFX2, NXF3 has the ability to bind and export mRNA from the nucleus to the cytoplasm, but it uses a completely different mechanism []. The expression of NXF3 appears to be restricted to the testis [].
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Protein Coding Gene
MGI:2685230 | Nxf3
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein
Q4ZGD9
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
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Publication
21308854 | J:171521
First Author: Zhou J
Year: 2011
Journal: Mol Reprod Dev
Title: Nxf3 is expressed in Sertoli cells, but is dispensable for spermatogenesis.
Volume: 78
Issue: 4
Pages: 241-9
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Publication
11545741 | -
First Author: Yang J
Year: 2001
Journal: Mol Cell
Title: Two closely related human nuclear export factors utilize entirely distinct export pathways.
Volume: 8
Issue: 2
Pages: 397-406
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Protein
B1AUS0
Organism: Mus musculus/domesticus
Length: 103  
Fragment?: true
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Publication
23438076 | J:198148
First Author: Yin Y
Year: 2013
Journal: Biochem J
Title: Nuclear export factor 3 is involved in regulating the expression of TGF-β3 in an mRNA export activity-independent manner in mouse Sertoli cells.
Volume: 452
Issue: 1
Pages: 67-78
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Protein Coding Gene
MGP_CAROLIEiJ_G0033415 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0036093 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0036074 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0036000 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0036062 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0035772 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2685230 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0036585 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0035061 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0035748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0035903 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0035839 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0035997 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0035873 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0036622 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0034752 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0035194 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0031955 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0034583 | -
Type: protein_coding_gene
Organism: Mus spretus
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Brain
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1610528
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Heart
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:3287428
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Intestine
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Kidney
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1684628
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Liver
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Lung
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Spleen
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Present
Sex: Male
Emaps: EMAPS:1797228
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Testis
Detected: true
Specimen Num: 9
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GXD Expression
GXD Expression
   
Probe: MGI:5646591
Assay Type: RT-PCR
Annotation Date: 2015-08-18
Strength: Absent
Sex: Female
Emaps: EMAPS:2991528
Stage: TS28
Assay Id: MGI:5648939
Age: postnatal
Image: 1
Specimen Label: Uterus
Detected: false
Specimen Num: 10
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Publication
15820316 | J:97549
First Author: Sasaki M
Year: 2005
Journal: Genomics
Title: Molecular cloning and functional characterization of mouse Nxf family gene products.
Volume: 85
Issue: 5
Pages: 641-53
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Publication
23677977 | J:199138
First Author: Zhou J
Year: 2013
Journal: Biol Reprod
Title: A 1.1-Mb segmental deletion on the X chromosome causes meiotic failure in male mice.
Volume: 88
Issue: 6
Pages: 159
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Publication
23675524 | J:200621
First Author: Vanmarsenille L
Year: 2013
Journal: PLoS One
Title: Generation and characterization of an Nxf7 knockout mouse to study NXF5 deficiency in a patient with intellectual disability.
Volume: 8
Issue: 5
Pages: e64144
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Publication
- | J:84900
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Journal: Database Download
Title: Integrating Computational Gene Models into the Mouse Genome Informatics (MGI) Database
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
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Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
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Allele
Del(XNxf2-Nxf3)1Jw | MGI:5297602
Name: deletion, Chr X, Jeremy Wang 1
Allele Type: Targeted
Attribute String: Null/knockout
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Genotype
Genotype
Symbol: Del(XNxf2-Nxf3)1Jw/+
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: ht
Has Mutant Allele: true
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Genotype
Genotype
Symbol: Del(XNxf2-Nxf3)1Jw/?
Background: involves: 129S4/SvJae * C57BL/6 * FVB
Zygosity: ot
Has Mutant Allele: true
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Publication
18364396 | J:202587
First Author: Hautbergue GM
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: Mutually exclusive interactions drive handover of mRNA from export adaptors to TAP.
Volume: 105
Issue: 13
Pages: 5154-9
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Protein
V9GX96
Organism: Mus musculus/domesticus
Length: 75  
Fragment?: false
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Publication
11566096 | J:71637
First Author: Jun L
Year: 2001
Journal: Curr Biol
Title: NXF5, a novel member of the nuclear RNA export factor family, is lost in a male patient with a syndromic form of mental retardation.
Volume: 11
Issue: 18
Pages: 1381-91
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Publication
9214641 | -
First Author: Segref A
Year: 1997
Journal: EMBO J
Title: Mex67p, a novel factor for nuclear mRNA export, binds to both poly(A)+ RNA and nuclear pores.
Volume: 16
Issue: 11
Pages: 3256-71
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Publication
11724776 | -
First Author: Zolotukhin AS
Year: 2002
Journal: J Biol Chem
Title: U2AF participates in the binding of TAP (NXF1) to mRNA.
Volume: 277
Issue: 6
Pages: 3935-42
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Protein Domain
IPR030217 | NXF_fam
Type: Family
Description: Mex67 is involved in the export of mRNA from the nucleus to the cytoplasm in Saccharomyces cerevisiae []. Vertebrate TAP (also called NXF1 for nuclear RNA export factor 1) is the orthologue of Mex67 []. TAP belongs to a multigene family with conserved modular architecture []. Other members of the family in humans are NXF2, NXF3, and NFX5. Both TAP(NXF1) and NXF2 bind mRNA and display RNA nuclear export activity []. NXF3 also has the ability to export mRNA from the nucleus to the cytoplasm but it uses a different mechanism []. NXF1 and NXF2 are predominantly nuclear, whereas the cytoplasmic presence of NXF3 and NXF5 suggests that they have a different cellular function [, ].Three functional domains of TAP have been characterised: the RNA-binding domain, the Nuclear Transport Factor 2 (NTF2)-like domain, and the ubiquitin-associated (UBA) domain. The RNA-binding domain (RBD) of TAP is located at its amino terminus and is composed of two RNA recognition motifs (RRMs) and one leucine-rich region [, ]. Once bound to mRNA, TAP escorts the messenger ribonucleoprotein (mRNP) to the nuclear pore, where TAP interacts with nucleoporins via the NTF2-like (NTF2L) and UBA domains [].
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Publication
24569167 | J:210663
First Author: Zhou J
Year: 2014
Journal: Hum Mol Genet
Title: Respiratory failure, cleft palate and epilepsy in the mouse model of human Xq22.1 deletion syndrome.
Volume: 23
Issue: 14
Pages: 3823-9
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Protein
A2AEI5
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: true
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Publication
11583626 | -
First Author: Fribourg S
Year: 2001
Journal: Mol Cell
Title: Structural basis for the recognition of a nucleoporin FG repeat by the NTF2-like domain of the TAP/p15 mRNA nuclear export factor.
Volume: 8
Issue: 3
Pages: 645-56
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Publication
9660949 | -
First Author: Grüter P
Year: 1998
Journal: Mol Cell
Title: TAP, the human homolog of Mex67p, mediates CTE-dependent RNA export from the nucleus.
Volume: 1
Issue: 5
Pages: 649-59
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Publication
10668806 | -
First Author: Bachi A
Year: 2000
Journal: RNA
Title: The C-terminal domain of TAP interacts with the nuclear pore complex and promotes export of specific CTE-bearing RNA substrates.
Volume: 6
Issue: 1
Pages: 136-58
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Protein
A2AEI4
Organism: Mus musculus/domesticus
Length: 155  
Fragment?: true
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Protein
V9GXM5
Organism: Mus musculus/domesticus
Length: 89  
Fragment?: true
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Protein
V9GXW3
Organism: Mus musculus/domesticus
Length: 282  
Fragment?: false
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Protein
V9GXF3
Organism: Mus musculus/domesticus
Length: 418  
Fragment?: false
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Protein
Q99JG4
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
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Publication
11073998 | -
First Author: Herold A
Year: 2000
Journal: Mol Cell Biol
Title: TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
Volume: 20
Issue: 23
Pages: 8996-9008
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Protein
Q99JX7
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
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Protein
Q4ZGD8
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
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Protein
Q99JG6
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
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Protein
Q8BP60
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
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Protein
Q99NI0
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
F7AR15
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: true
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Protein
Q99MW6
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
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Protein
Q8R499
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
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Protein
Q99JG5
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: true
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Protein
Q80SZ6
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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Cambridge CB2 3EH, United Kingdom