|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 93 out of 93 for Nxt2

0.048s

Categories

Hits by Pathway

Hits by Category

Hits by Strain

Type Details Score
Gene
55916 | NXT2
Type: gene
Organism: human
•
•
•
•
•
Gene
100145163 | nxt2
Type: gene
Organism: frog, western clawed
•
•
•
•
•
Gene
315352 | Nxt2
Type: gene
Organism: rat
•
•
•
•
•
Gene
612945 | NXT2
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
473728 | NXT2
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
513043 | NXT2
Type: gene
Organism: cattle
•
•
•
•
•
Gene
422346 | NXT2
Type: gene
Organism: chicken
•
•
•
•
•
Gene
751738 | nxt2
Type: gene
Organism: zebrafish
•
•
•
•
•
Gene
704593 | NXT2
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:2147914 | Nxt2
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
29563520 | J:263089
First Author: Khan M
Year: 2018
Journal: Sci Rep
Title: The evolutionarily conserved genes: Tex37, Ccdc73, Prss55 and Nxt2 are dispensable for fertility in mice.
Volume: 8
Issue: 1
Pages: 4975
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0033463 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0036148 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0036125 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0036051 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0036116 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0035824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_2147914 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0036639 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0035115 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0035801 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0035959 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0035893 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0036050 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0035929 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0036676 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0034809 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0035250 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0032003 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0034634 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
16790844 | J:231287
First Author: Lai D
Year: 2006
Journal: RNA
Title: The fragile X mental retardation protein interacts with a distinct mRNA nuclear export factor NXF2.
Volume: 12
Issue: 8
Pages: 1446-9
•
•
•
•
•
Publication
15820316 | J:97549
First Author: Sasaki M
Year: 2005
Journal: Genomics
Title: Molecular cloning and functional characterization of mouse Nxf family gene products.
Volume: 85
Issue: 5
Pages: 641-53
•
•
•
•
•
Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
•
•
•
•
•
Publication
- | J:66660
       
First Author: Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration
Year: 2001
Title: LocusLink Collaboration
•
•
•
•
•
Publication
- | J:80155
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations for FANTOM2 data
•
•
•
•
•
Publication
- | J:57656
     
First Author: Lennon G
Year: 1999
Journal: Database Download
Title: WashU-HHMI Mouse EST Project
•
•
•
•
•
Publication
- | J:72247
       
First Author: DDB, FB, MGI, GOA, ZFIN curators
Year: 2001
Title: Gene Ontology annotation through association of InterPro records with GO terms
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:68900
     
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
•
•
•
•
•
Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
•
•
•
•
•
Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
•
•
•
•
•
Publication
- | J:157972
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
- | J:144087
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
•
•
•
•
•
Protein
Q6P250
Organism: Mus musculus/domesticus
Length: 197  
Fragment?: true
•
•
•
•
•
Publication
11129791 | -
First Author: Stewart M
Year: 2000
Journal: Cell Struct Funct
Title: Insights into the molecular mechanism of nuclear trafficking using nuclear transport factor 2 (NTF2).
Volume: 25
Issue: 4
Pages: 217-25
•
•
•
•
•
Publication
10930458 | -
First Author: Quimby BB
Year: 2000
Journal: Mol Biol Cell
Title: The interaction between Ran and NTF2 is required for cell cycle progression.
Volume: 11
Issue: 8
Pages: 2617-29
•
•
•
•
•
Protein Domain
IPR018222 | Nuclear_transport_factor_2_euk
Type: Domain
Description: Ran () is an evolutionary conserved member of the Ras superfamily of small GTPases that regulates all receptor-mediated transport between the nucleus and the cytoplasm. Import receptors bind their cargos in the cytoplasm where the concentration of RanGTP is low and release their cargos in the nucleus where the concentration of RanGTP is high []. Export receptors respond to Ran GTP in the oppositemanner. Nuclear transport factor 2 (NTF2) is a homodimer of approximately 14kDa subunits which stimulates efficient nuclear import of a cargo protein. NTF2 binds to both RanGDP and FxFG repeat-containing nucleoporins. NTF2 binds to RanGDP sufficiently strongly for the complex to remain intact during transport through NPCs, but the interaction between NTF2 and FxFG nucleoporins is much more transient, which would enable NTF2 to move through the NPC by hopping from one repeat to another [, ].NTF2 folds into a cone with a deep hydrophobic cavity, the opening of which is surrounded by several negatively charged residues. RanGDP binds to NTF2 by inserting a conserved phenylalanine residue into the hydrophobic pocket of NTF2 and making electrostatic interactions with the conserved negatively charged residues that surround the cavity.This entry contains predominantly eukaryotic proteins. The following proteins contain a region similar to NTF2:Eukaryotic NXF proteins []. These are nuclear mRNA export factors. These proteins contain, in addition to a NTF2 domain, a number of leucine-rich repeats and a UBA domain.Eukaryotic NXT1/NXT2 proteins []. These proteins are stimulators of protein export for NES-containing proteins. The also play a role in mRNA nuclear export. They heterodimerize with NFX proteins. In contrast to NTF2, NXT1 and NXT2 preferentially bind RanGTP.Eukaryotic Ras-GTPase-activating protein (GAP)-binding proteins (G3BP's). These proteins contain one NTF2 domain and one RRM (see ).
•
•
•
•
•
Protein
Q9QZV9
Organism: Mus musculus/domesticus
Length: 140  
Fragment?: false
•
•
•
•
•
Protein
Q3UNA4
Organism: Mus musculus/domesticus
Length: 142  
Fragment?: false
•
•
•
•
•
Protein
P61971
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
•
•
•
•
•
Protein
A0A1D5RLR1
Organism: Mus musculus/domesticus
Length: 61  
Fragment?: true
•
•
•
•
•
Protein
Q3U8H8
Organism: Mus musculus/domesticus
Length: 127  
Fragment?: false
•
•
•
•
•
Protein
Q3UR88
Organism: Mus musculus/domesticus
Length: 386  
Fragment?: false
•
•
•
•
•
Protein
A0A0J9YTQ8
Organism: Mus musculus/domesticus
Length: 133  
Fragment?: true
•
•
•
•
•
Protein
A0A0J9YUY8
Organism: Mus musculus/domesticus
Length: 117  
Fragment?: true
•
•
•
•
•
Protein
Q99JG4
Organism: Mus musculus/domesticus
Length: 187  
Fragment?: true
•
•
•
•
•
Publication
11073998 | -
First Author: Herold A
Year: 2000
Journal: Mol Cell Biol
Title: TAP (NXF1) belongs to a multigene family of putative RNA export factors with a conserved modular architecture.
Volume: 20
Issue: 23
Pages: 8996-9008
•
•
•
•
•
Protein
P97379
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
•
•
•
•
•
Protein
Q542W3
Organism: Mus musculus/domesticus
Length: 449  
Fragment?: false
•
•
•
•
•
Protein
Q3U931
Organism: Mus musculus/domesticus
Length: 448  
Fragment?: false
•
•
•
•
•
Protein
Q3U6B1
Organism: Mus musculus/domesticus
Length: 550  
Fragment?: true
•
•
•
•
•
Protein
Q3U541
Organism: Mus musculus/domesticus
Length: 482  
Fragment?: false
•
•
•
•
•
Protein
P97855
Organism: Mus musculus/domesticus
Length: 465  
Fragment?: false
•
•
•
•
•
Protein
Q99JX7
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
•
•
•
•
•
Protein
Q4ZGD9
Organism: Mus musculus/domesticus
Length: 553  
Fragment?: false
•
•
•
•
•
Protein
Q4ZGD8
Organism: Mus musculus/domesticus
Length: 691  
Fragment?: false
•
•
•
•
•
Protein
Q571F9
Organism: Mus musculus/domesticus
Length: 505  
Fragment?: true
•
•
•
•
•
Protein
Q99JG6
Organism: Mus musculus/domesticus
Length: 473  
Fragment?: true
•
•
•
•
•
Protein
Q8BP60
Organism: Mus musculus/domesticus
Length: 618  
Fragment?: false
•
•
•
•
•
Protein
Q99NI0
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
•
•
•
•
•
Protein
F7AR15
Organism: Mus musculus/domesticus
Length: 475  
Fragment?: true
•
•
•
•
•
Protein
Q99MW6
Organism: Mus musculus/domesticus
Length: 685  
Fragment?: false
•
•
•
•
•
Protein
Q8R499
Organism: Mus musculus/domesticus
Length: 671  
Fragment?: false
•
•
•
•
•
Publication
12019565 | -
 
First Author: Steggerda SM
Year: 2002
Journal: Int Rev Cytol
Title: Regulation of nuclear import and export by the GTPase Ran.
Volume: 217
Pages: 41-91
•
•
•
•
•
Protein
Q99JG5
Organism: Mus musculus/domesticus
Length: 509  
Fragment?: true
•
•
•
•
•
Protein
Q80SZ6
Organism: Mus musculus/domesticus
Length: 620  
Fragment?: false
•
•
•
•
•
Publication
15489334 | -
First Author: Gerhard DS
Year: 2004
Journal: Genome Res
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
Volume: 14
Issue: 10B
Pages: 2121-7
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom