Type |
Details |
Score |
Gene |
|
•
•
•
•
•
|
Polymorphic Pseudogene |
Type: |
polymorphic_pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Yoshii K |
Year: |
2013 |
Journal: |
Arch Virol |
Title: |
Susceptibility to flavivirus-specific antiviral response of Oas1b affects the neurovirulence of the Far-Eastern subtype of tick-borne encephalitis virus. |
Volume: |
158 |
Issue: |
5 |
Pages: |
1039-46 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scherbik SV |
Year: |
2007 |
Journal: |
Virology |
Title: |
Knock-in of the Oas1b(r) allele into a flavivirus-induced disease susceptible mouse generates the resistant phenotype. |
Volume: |
368 |
Issue: |
2 |
Pages: |
232-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Elbahesh H |
Year: |
2011 |
Journal: |
Virology |
Title: |
The Flvr-encoded murine oligoadenylate synthetase 1b (Oas1b) suppresses 2-5A synthesis in intact cells. |
Volume: |
409 |
Issue: |
2 |
Pages: |
262-70 |
|
•
•
•
•
•
|
Publication |
First Author: |
Perelygin AA |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Positional cloning of the murine flavivirus resistance gene. |
Volume: |
99 |
Issue: |
14 |
Pages: |
9322-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kajaste-Rudnitski A |
Year: |
2006 |
Journal: |
J Biol Chem |
Title: |
The 2',5'-oligoadenylate synthetase 1b is a potent inhibitor of West Nile virus replication inside infected cells. |
Volume: |
281 |
Issue: |
8 |
Pages: |
4624-37 |
|
•
•
•
•
•
|
Publication |
First Author: |
Green R |
Year: |
2017 |
Journal: |
G3 (Bethesda) |
Title: |
Oas1b-dependent Immune Transcriptional Profiles of West Nile Virus Infection in the Collaborative Cross. |
Volume: |
7 |
Issue: |
6 |
Pages: |
1665-1682 |
|
•
•
•
•
•
|
Publication |
First Author: |
Peterson E |
Year: |
2019 |
Journal: |
J Biol Chem |
Title: |
Biochemical characterization of the mouse ABCF3 protein, a partner of the flavivirus-resistance protein OAS1B. |
Volume: |
294 |
Issue: |
41 |
Pages: |
14937-14952 |
|
•
•
•
•
•
|
Publication |
First Author: |
Courtney SC |
Year: |
2012 |
Journal: |
J Virol |
Title: |
Identification of novel host cell binding partners of Oas1b, the protein conferring resistance to flavivirus-induced disease in mice. |
Volume: |
86 |
Issue: |
15 |
Pages: |
7953-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Manet C |
Year: |
2020 |
Journal: |
J Virol |
Title: |
Genetic Diversity of Collaborative Cross Mice Controls Viral Replication, Clinical Severity, and Brain Pathology Induced by Zika Virus Infection, Independently of Oas1b. |
Volume: |
94 |
Issue: |
3 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Jasperse BA |
Year: |
2023 |
Journal: |
J Virol |
Title: |
Neuroinvasive Flavivirus Pathogenesis Is Restricted by Host Genetic Factors in Collaborative Cross Mice, Independently of Oas1b. |
Volume: |
97 |
Issue: |
7 |
Pages: |
e0071523 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Polymorphic Pseudogene |
Type: |
polymorphic_pseudogene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Publication |
First Author: |
Kakuta S |
Year: |
2002 |
Journal: |
J Interferon Cytokine Res |
Title: |
Genomic structure of the mouse 2',5'-oligoadenylate synthetase gene family. |
Volume: |
22 |
Issue: |
9 |
Pages: |
981-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Eskildsen S |
Year: |
2002 |
Journal: |
Cell Mol Life Sci |
Title: |
Gene structure of the murine 2'-5'-oligoadenylate synthetase family. |
Volume: |
59 |
Issue: |
7 |
Pages: |
1212-22 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rutherford MN |
Year: |
1991 |
Journal: |
Nucleic Acids Res |
Title: |
The murine 2-5A synthetase locus: three distinct transcripts from two linked genes. |
Volume: |
19 |
Issue: |
8 |
Pages: |
1917-24 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kristiansen H |
Year: |
2011 |
Journal: |
J Interferon Cytokine Res |
Title: |
The oligoadenylate synthetase family: an ancient protein family with multiple antiviral activities. |
Volume: |
31 |
Issue: |
1 |
Pages: |
41-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mashimo T |
Year: |
2002 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A nonsense mutation in the gene encoding 2'-5'-oligoadenylate synthetase/L1 isoform is associated with West Nile virus susceptibility in laboratory mice. |
Volume: |
99 |
Issue: |
17 |
Pages: |
11311-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ghosh SK |
Year: |
1991 |
Journal: |
J Biol Chem |
Title: |
Cloning, sequencing, and expression of two murine 2'-5'-oligoadenylate synthetases. Structure-function relationships. |
Volume: |
266 |
Issue: |
23 |
Pages: |
15293-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Webster LT |
Year: |
1937 |
Journal: |
J Exp Med |
Title: |
INHERITANCE OF RESISTANCE OF MICE TO ENTERIC BACTERIAL AND NEUROTROPIC VIRUS INFECTIONS. |
Volume: |
65 |
Issue: |
2 |
Pages: |
261-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sabin AB |
Year: |
1952 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Nature of Inherited Resistance to Viruses Affecting the Nervous System. |
Volume: |
38 |
Issue: |
6 |
Pages: |
540-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Green MC |
Year: |
1979 |
Journal: |
Mouse News Lett |
Title: |
Flv |
Volume: |
60 |
|
Pages: |
29 |
|
•
•
•
•
•
|
Publication |
First Author: |
Darnell MB |
Year: |
1974 |
Journal: |
J Infect Dis |
Title: |
Genetically determined resistance to infection with group B arboviruses. I. Distribution of the resistance gene among various mouse populations and characteristics of gene expression in vivo. |
Volume: |
129 |
Issue: |
3 |
Pages: |
240-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graham JB |
Year: |
2019 |
Journal: |
J Infect Dis |
Title: |
Immune Correlates of Protection From West Nile Virus Neuroinvasion and Disease. |
Volume: |
219 |
Issue: |
7 |
Pages: |
1162-1171 |
|
•
•
•
•
•
|
Publication |
First Author: |
Brinton MA |
Year: |
1982 |
Journal: |
Infect Immun |
Title: |
Interferon independence of genetically controlled resistance to flaviviruses. |
Volume: |
36 |
Issue: |
1 |
Pages: |
284-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Urosevic N |
Year: |
1999 |
Journal: |
J Gen Virol |
Title: |
Development and characterization of new flavivirus-resistant mouse strains bearing Flv(r)-like and Flv(mr) alleles from wild or wild-derived mice. |
Volume: |
80 ( Pt 4) |
|
Pages: |
897-906 |
|
•
•
•
•
•
|
Publication |
First Author: |
GOODMAN GT |
Year: |
1962 |
Journal: |
J Cell Comp Physiol |
Title: |
Study of the mechanism of innate resistance to virus infection. |
Volume: |
59 |
|
Pages: |
333-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stoddart CW |
Year: |
2004 |
Journal: |
Mamm Genome |
Title: |
A novel mouse Chr5 locus Diht controls dopamine-induced hypothermia. |
Volume: |
15 |
Issue: |
11 |
Pages: |
901-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hanson B |
Year: |
1969 |
Journal: |
Microbios |
Title: |
Interferon-mediated natural resistance of mice to arbo B virus infection |
Volume: |
1B |
|
Pages: |
51-68 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gröschel D |
Year: |
1965 |
Journal: |
Arch Gesamte Virusforsch |
Title: |
Development of a virus-resistant inbred mouse strain for the study of innate resistance to Arbo B viruses. |
Volume: |
17 |
Issue: |
3 |
Pages: |
379-91 |
|
•
•
•
•
•
|
Publication |
First Author: |
Smith AL |
Year: |
1980 |
|
Title: |
Genetic resistance to lethal flavivirus infection: Detection of interfering virus produced in vivo |
|
|
Pages: |
305-12 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhatt PN |
Year: |
1976 |
Journal: |
J Infect Dis |
Title: |
Genetic resistance to lethal flavivrus encephalitis. II. Effect of immunosuppression. |
Volume: |
134 |
Issue: |
2 |
Pages: |
166-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sangster MY |
Year: |
1993 |
Journal: |
J Virol |
Title: |
Genetic studies of flavivirus resistance in inbred strains derived from wild mice: evidence for a new resistance allele at the flavivirus resistance locus (Flv). |
Volume: |
67 |
Issue: |
1 |
Pages: |
340-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carlson HL |
Year: |
2020 |
Journal: |
Genesis |
Title: |
Development and functional characterization of a lncRNA-HIT conditional loss of function allele. |
Volume: |
58 |
Issue: |
3-4 |
Pages: |
e23351 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Kumar S |
Year: |
2000 |
Journal: |
Mol Biol Evol |
Title: |
Expansion and molecular evolution of the interferon-induced 2'-5' oligoadenylate synthetase gene family. |
Volume: |
17 |
Issue: |
5 |
Pages: |
738-50 |
|
•
•
•
•
•
|
Publication |
First Author: |
Justesen J |
Year: |
2000 |
Journal: |
Cell Mol Life Sci |
Title: |
Gene structure and function of the 2'-5'-oligoadenylate synthetase family. |
Volume: |
57 |
Issue: |
11 |
Pages: |
1593-612 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cohen B |
Year: |
1988 |
Journal: |
EMBO J |
Title: |
Enhancer-like interferon responsive sequences of the human and murine (2'-5') oligoadenylate synthetase gene promoters. |
Volume: |
7 |
Issue: |
5 |
Pages: |
1411-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sangster MY |
Year: |
1994 |
Journal: |
J Virol |
Title: |
Mapping the Flv locus controlling resistance to flaviviruses on mouse chromosome 5. |
Volume: |
68 |
Issue: |
1 |
Pages: |
448-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sandberg K |
Year: |
1994 |
Journal: |
J Immunol |
Title: |
Altered tissue distribution of viral replication and T cell spreading is pivotal in the protection against fatal lymphocytic choriomeningitis in mice after neutralization of IFN-alpha/beta. |
Volume: |
153 |
Issue: |
1 |
Pages: |
220-31 |
|
•
•
•
•
•
|
Publication |
First Author: |
Urosevic N |
Year: |
1995 |
Journal: |
Mamm Genome |
Title: |
Low resolution mapping around the flavivirus resistance locus (Flv) on mouse chromosome 5. |
Volume: |
6 |
Issue: |
7 |
Pages: |
454-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mashimo T |
Year: |
2003 |
Journal: |
Genomics |
Title: |
Structural and functional genomics and evolutionary relationships in the cluster of genes encoding murine 2',5'-oligoadenylate synthetases. |
Volume: |
82 |
Issue: |
5 |
Pages: |
537-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
KANTOCH M |
Year: |
1963 |
Journal: |
J Exp Med |
Title: |
The cellular nature of genetic susceptibility to a virus. |
Volume: |
117 |
|
Pages: |
781-98 |
|
•
•
•
•
•
|
Publication |
First Author: |
Diez-Roux G |
Year: |
2011 |
Journal: |
PLoS Biol |
Title: |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. |
Volume: |
9 |
Issue: |
1 |
Pages: |
e1000582 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6695977 |
Assay Type: |
RT-PCR |
Annotation Date: |
2021-05-04 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603921 |
|
Stage: |
TS21 |
Assay Id: |
MGI:6696124 |
Age: |
embryonic day 13.5 |
Image: |
3 |
|
Specimen Label: |
+/+;CMV-Cre/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Committee on Standardized Genetic Nomenclature for Mice |
Year: |
1993 |
|
Title: |
Nomenclature rule change to delete hyphens and parentheses from mouse locus symbols |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Allen Institute for Brain Science |
Year: |
2004 |
Journal: |
Allen Institute |
Title: |
Allen Brain Atlas: mouse riboprobes |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shellam GR |
Year: |
1993 |
Journal: |
Mouse Genome |
Title: |
Characterisation of allelic forms at the retinal degeneration (rd) and beta-glucuronidase (Gus) loci for the mapping of the flavivirus resistance (Flv) gene on mouse chromosome 5 |
Volume: |
91 |
Issue: |
3 |
Pages: |
572-574 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sangster MY |
Year: |
1992 |
Journal: |
Mouse Genome |
Title: |
Inheritance of coat colour in the MOLD/Rk inbred strain |
Volume: |
90 |
Issue: |
2 |
Pages: |
212 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
376
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Pulit-Penaloza JA |
Year: |
2012 |
Journal: |
Virology |
Title: |
Activation of Oas1a gene expression by type I IFN requires both STAT1 and STAT2 while only STAT2 is required for Oas1b activation. |
Volume: |
425 |
Issue: |
2 |
Pages: |
71-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graham JB |
Year: |
2015 |
Journal: |
MBio |
Title: |
Genetic diversity in the collaborative cross model recapitulates human West Nile virus disease outcomes. |
Volume: |
6 |
Issue: |
3 |
Pages: |
e00493-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gerhard DS |
Year: |
2004 |
Journal: |
Genome Res |
Title: |
The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). |
Volume: |
14 |
Issue: |
10B |
Pages: |
2121-7 |
|
•
•
•
•
•
|