Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
One of the major base lesions induced by oxidative stress is 8-oxoguanine (8-oxoG), one of the oxidised forms of guanine. 8-oxoguanine DNA glycosylase (also known as N-glycosylase/DNA lyase) functions in base excision repair and is responsible for the excision of 8-oxoguanine. It has beta-lyase activity thatnicks DNA 3' to the lesion [, , ]. |
|
•
•
•
•
•
|
Publication |
First Author: |
Aburatani H |
Year: |
1997 |
Journal: |
Cancer Res |
Title: |
Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue. |
Volume: |
57 |
Issue: |
11 |
Pages: |
2151-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kovtun IV |
Year: |
2007 |
Journal: |
Nature |
Title: |
OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells. |
Volume: |
447 |
Issue: |
7143 |
Pages: |
447-52 |
|
•
•
•
•
•
|
Publication |
First Author: |
van der Kemp PA |
Year: |
1996 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine. |
Volume: |
93 |
Issue: |
11 |
Pages: |
5197-202 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kakehashi A |
Year: |
2017 |
Journal: |
Int J Mol Sci |
Title: |
Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis. |
Volume: |
18 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Sakumi K |
Year: |
2003 |
Journal: |
Cancer Res |
Title: |
Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption. |
Volume: |
63 |
Issue: |
5 |
Pages: |
902-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yuzefovych LV |
Year: |
2016 |
Journal: |
Cancer Res |
Title: |
Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis. |
Volume: |
76 |
Issue: |
1 |
Pages: |
30-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Song C |
Year: |
2024 |
Journal: |
Int Immunopharmacol |
Title: |
OGG1 promoted lung fibrosis by activating fibroblasts via interacting with Snail1. |
Volume: |
126 |
|
Pages: |
111148 |
|
•
•
•
•
•
|
Publication |
First Author: |
Komakula SSB |
Year: |
2018 |
Journal: |
Sci Rep |
Title: |
The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue. |
Volume: |
8 |
Issue: |
1 |
Pages: |
14886 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bjørge MD |
Year: |
2015 |
Journal: |
Cell Rep |
Title: |
Synergistic Actions of Ogg1 and Mutyh DNA Glycosylases Modulate Anxiety-like Behavior in Mice. |
Volume: |
13 |
Issue: |
12 |
Pages: |
2671-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kunisada M |
Year: |
2005 |
Journal: |
Cancer Res |
Title: |
8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis. |
Volume: |
65 |
Issue: |
14 |
Pages: |
6006-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boiteux S |
Year: |
1998 |
Journal: |
Free Radic Res |
Title: |
Excision repair of 8-hydroxyguanine in mammalian cells: the mouse Ogg1 protein as a model. |
Volume: |
29 |
Issue: |
6 |
Pages: |
487-97 |
|
•
•
•
•
•
|
Publication |
First Author: |
Boiteux S |
Year: |
2000 |
Journal: |
Arch Biochem Biophys |
Title: |
The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis. |
Volume: |
377 |
Issue: |
1 |
Pages: |
1-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chimienti G |
Year: |
2019 |
Journal: |
Int J Mol Sci |
Title: |
Deletion of OGG1 Results in a Differential Signature of Oxidized Purine Base Damage in mtDNA Regions. |
Volume: |
20 |
Issue: |
13 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Lee CJ |
Year: |
2011 |
Journal: |
Toxicol Sci |
Title: |
Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture. |
Volume: |
122 |
Issue: |
1 |
Pages: |
146-56 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tominaga Y |
Year: |
2004 |
Journal: |
Nucleic Acids Res |
Title: |
MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain. |
Volume: |
32 |
Issue: |
10 |
Pages: |
3198-211 |
|
•
•
•
•
•
|
Publication |
First Author: |
Simon H |
Year: |
2020 |
Journal: |
PLoS One |
Title: |
OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model. |
Volume: |
15 |
Issue: |
1 |
Pages: |
e0227501 |
|
•
•
•
•
•
|
Publication |
First Author: |
Oka S |
Year: |
2021 |
Journal: |
Sci Rep |
Title: |
MTH1 and OGG1 maintain a low level of 8-oxoguanine in Alzheimer's brain, and prevent the progression of Alzheimer's pathogenesis. |
Volume: |
11 |
Issue: |
1 |
Pages: |
5819 |
|
•
•
•
•
•
|
Publication |
First Author: |
Karahalil B |
Year: |
2003 |
Journal: |
J Biol Chem |
Title: |
Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases. |
Volume: |
278 |
Issue: |
36 |
Pages: |
33701-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie Y |
Year: |
2008 |
Journal: |
Carcinogenesis |
Title: |
Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation. |
Volume: |
29 |
Issue: |
4 |
Pages: |
722-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Souza-Pinto NC |
Year: |
2009 |
Journal: |
Mol Cell Biol |
Title: |
The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells. |
Volume: |
29 |
Issue: |
16 |
Pages: |
4441-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Russo MT |
Year: |
2004 |
Journal: |
Cancer Res |
Title: |
Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases. |
Volume: |
64 |
Issue: |
13 |
Pages: |
4411-4 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arai T |
Year: |
2006 |
Journal: |
Toxicology |
Title: |
The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA. |
Volume: |
221 |
Issue: |
2-3 |
Pages: |
179-86 |
|
•
•
•
•
•
|
Publication |
First Author: |
Tani M |
Year: |
1998 |
Journal: |
Mamm Genome |
Title: |
Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage. |
Volume: |
9 |
Issue: |
1 |
Pages: |
32-7 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
345
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
345
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Nash HM |
Year: |
1996 |
Journal: |
Curr Biol |
Title: |
Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily. |
Volume: |
6 |
Issue: |
8 |
Pages: |
968-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yogianti F |
Year: |
2012 |
Journal: |
Mutagenesis |
Title: |
Skin tumours induced by narrowband UVB have higher frequency of p53 mutations than tumours induced by broadband UVB independent of Ogg1 genotype. |
Volume: |
27 |
Issue: |
6 |
Pages: |
637-43 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xie Y |
Year: |
2004 |
Journal: |
Cancer Res |
Title: |
Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors. |
Volume: |
64 |
Issue: |
9 |
Pages: |
3096-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mizuno Y |
Year: |
2022 |
Journal: |
Neurosci Res |
Title: |
Deficiency of MTH1 and/or OGG1 increases the accumulation of 8-oxoguanine in the brain of the AppNL-G-F/NL-G-F knock-in mouse model of Alzheimer's disease, accompanied by accelerated microgliosis and reduced anxiety-like behavior. |
Volume: |
177 |
|
Pages: |
118-134 |
|
•
•
•
•
•
|
Publication |
First Author: |
Choi JY |
Year: |
1999 |
Journal: |
Free Radic Biol Med |
Title: |
Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation. |
Volume: |
27 |
Issue: |
7-8 |
Pages: |
848-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pao PC |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease. |
Volume: |
11 |
Issue: |
1 |
Pages: |
2484 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rosenquist TA |
Year: |
1997 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase. |
Volume: |
94 |
Issue: |
14 |
Pages: |
7429-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arai T |
Year: |
2003 |
Journal: |
Cancer Res |
Title: |
Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA. |
Volume: |
63 |
Issue: |
14 |
Pages: |
4287-92 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kinoshita A |
Year: |
2007 |
Journal: |
Cancer Sci |
Title: |
Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice. |
Volume: |
98 |
Issue: |
6 |
Pages: |
803-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klungland A |
Year: |
1999 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage. |
Volume: |
96 |
Issue: |
23 |
Pages: |
13300-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang W |
Year: |
2011 |
Journal: |
J Neurosci |
Title: |
Mitochondrial DNA damage level determines neural stem cell differentiation fate. |
Volume: |
31 |
Issue: |
26 |
Pages: |
9746-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yuzefovych LV |
Year: |
2013 |
Journal: |
Endocrinology |
Title: |
Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1. |
Volume: |
154 |
Issue: |
8 |
Pages: |
2640-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ondovcik SL |
Year: |
2013 |
Journal: |
Toxicol Appl Pharmacol |
Title: |
Sensitivity to methylmercury toxicity is enhanced in oxoguanine glycosylase 1 knockout murine embryonic fibroblasts and is dependent on cellular proliferation capacity. |
Volume: |
270 |
Issue: |
1 |
Pages: |
23-30 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wong AW |
Year: |
2008 |
Journal: |
J Neurosci |
Title: |
Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits. |
Volume: |
28 |
Issue: |
36 |
Pages: |
9047-54 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rozalski R |
Year: |
2005 |
Journal: |
Int J Biochem Cell Biol |
Title: |
Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice. |
Volume: |
37 |
Issue: |
6 |
Pages: |
1331-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sampath H |
Year: |
2012 |
Journal: |
PLoS One |
Title: |
8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction. |
Volume: |
7 |
Issue: |
12 |
Pages: |
e51697 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kunisada M |
Year: |
2011 |
Journal: |
Am J Pathol |
Title: |
Increased expression of versican in the inflammatory response to UVB- and reactive oxygen species-induced skin tumorigenesis. |
Volume: |
179 |
Issue: |
6 |
Pages: |
3056-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Vartanian V |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e0181687 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cheresh P |
Year: |
2015 |
Journal: |
Am J Respir Cell Mol Biol |
Title: |
Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice. |
Volume: |
52 |
Issue: |
1 |
Pages: |
25-36 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mori M |
Year: |
2001 |
Journal: |
Free Radic Biol Med |
Title: |
Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence. |
Volume: |
30 |
Issue: |
10 |
Pages: |
1130-6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Conlon KA |
Year: |
2004 |
Journal: |
DNA Repair (Amst) |
Title: |
Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis. |
Volume: |
3 |
Issue: |
12 |
Pages: |
1601-15 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bhakat KK |
Year: |
2006 |
Journal: |
Mol Cell Biol |
Title: |
Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo. |
Volume: |
26 |
Issue: |
5 |
Pages: |
1654-65 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wu M |
Year: |
2011 |
Journal: |
Infect Immun |
Title: |
Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epithelial cells and in mice. |
Volume: |
79 |
Issue: |
1 |
Pages: |
75-87 |
|
•
•
•
•
•
|
Publication |
First Author: |
Aguilera-Aguirre L |
Year: |
2015 |
Journal: |
Free Radic Biol Med |
Title: |
Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes. |
Volume: |
81 |
|
Pages: |
107-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bacsi A |
Year: |
2013 |
Journal: |
DNA Repair (Amst) |
Title: |
Down-regulation of 8-oxoguanine DNA glycosylase 1 expression in the airway epithelium ameliorates allergic lung inflammation. |
Volume: |
12 |
Issue: |
1 |
Pages: |
18-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Arai T |
Year: |
2002 |
Journal: |
Carcinogenesis |
Title: |
High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress. |
Volume: |
23 |
Issue: |
12 |
Pages: |
2005-10 |
|
•
•
•
•
•
|
Publication |
First Author: |
de Souza-Pinto NC |
Year: |
2001 |
Journal: |
Cancer Res |
Title: |
Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice. |
Volume: |
61 |
Issue: |
14 |
Pages: |
5378-81 |
|
•
•
•
•
•
|
Publication |
First Author: |
Winter DB |
Year: |
2003 |
Journal: |
J Immunol |
Title: |
Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase. |
Volume: |
170 |
Issue: |
11 |
Pages: |
5558-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Scheffler K |
Year: |
2018 |
Journal: |
DNA Repair (Amst) |
Title: |
8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis. |
Volume: |
61 |
|
Pages: |
56-62 |
|
•
•
•
•
•
|
Publication |
First Author: |
Yogianti F |
Year: |
2014 |
Journal: |
J Invest Dermatol |
Title: |
Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis. |
Volume: |
134 |
Issue: |
10 |
Pages: |
2610-2619 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Y |
Year: |
2020 |
Journal: |
FASEB J |
Title: |
8-Oxoguanine DNA glycosylase modulates the cell transformation process in pulmonary fibrosis by inhibiting Smad2/3 and interacting with Smad7. |
Volume: |
34 |
Issue: |
10 |
Pages: |
13461-13473 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ondovcik SL |
Year: |
2012 |
Journal: |
Toxicol Sci |
Title: |
Oxoguanine glycosylase 1 (OGG1) protects cells from DNA double-strand break damage following methylmercury (MeHg) exposure. |
Volume: |
128 |
Issue: |
1 |
Pages: |
272-83 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mulder JE |
Year: |
2015 |
Journal: |
Mutagenesis |
Title: |
Effect of 8-oxoguanine glycosylase deficiency on aflatoxin B1 tumourigenicity in mice. |
Volume: |
30 |
Issue: |
3 |
Pages: |
401-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jałoszyński P |
Year: |
2007 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice. |
Volume: |
364 |
Issue: |
4 |
Pages: |
966-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen SH |
Year: |
2010 |
Journal: |
Mutat Res |
Title: |
In vitro investigations of glycidamide-induced DNA lesions in mouse male germ cells and in mouse and human lymphocytes. |
Volume: |
696 |
Issue: |
1 |
Pages: |
55-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Wang Z |
Year: |
2010 |
Journal: |
PLoS Genet |
Title: |
Characterization of oxidative guanine damage and repair in mammalian telomeres. |
Volume: |
6 |
Issue: |
5 |
Pages: |
e1000951 |
|
•
•
•
•
•
|
Publication |
First Author: |
Graupner A |
Year: |
2015 |
Journal: |
Mutagenesis |
Title: |
Genotoxic effects of two-generational selenium deficiency in mouse somatic and testicular cells. |
Volume: |
30 |
Issue: |
2 |
Pages: |
217-25 |
|
•
•
•
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Publication |
First Author: |
Komakula SSB |
Year: |
2021 |
Journal: |
Int J Mol Sci |
Title: |
A Novel Role for the DNA Repair Enzyme 8-Oxoguanine DNA Glycosylase in Adipogenesis. |
Volume: |
22 |
Issue: |
3 |
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Publication |
First Author: |
Tumurkhuu G |
Year: |
2020 |
Journal: |
Front Immunol |
Title: |
Oxidative DNA Damage Accelerates Skin Inflammation in Pristane-Induced Lupus Model. |
Volume: |
11 |
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Pages: |
554725 |
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Publication |
First Author: |
Osterod M |
Year: |
2001 |
Journal: |
Carcinogenesis |
Title: |
Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice. |
Volume: |
22 |
Issue: |
9 |
Pages: |
1459-63 |
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Publication |
First Author: |
Jalland CM |
Year: |
2014 |
Journal: |
Free Radic Biol Med |
Title: |
Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage. |
Volume: |
68 |
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Pages: |
1-7 |
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Publication |
First Author: |
Kauppila JHK |
Year: |
2018 |
Journal: |
Nucleic Acids Res |
Title: |
Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice. |
Volume: |
46 |
Issue: |
13 |
Pages: |
6642-6669 |
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Publication |
First Author: |
Trapp C |
Year: |
2007 |
Journal: |
Mutat Res |
Title: |
The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice. |
Volume: |
625 |
Issue: |
1-2 |
Pages: |
155-63 |
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Publication |
First Author: |
Ye Y |
Year: |
2017 |
Journal: |
J Immunol |
Title: |
DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia. |
Volume: |
198 |
Issue: |
7 |
Pages: |
2844-2853 |
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Publication |
First Author: |
Sheng Z |
Year: |
2012 |
Journal: |
J Clin Invest |
Title: |
8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair. |
Volume: |
122 |
Issue: |
12 |
Pages: |
4344-61 |
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Publication |
First Author: |
Habib SL |
Year: |
2008 |
Journal: |
Am J Physiol Renal Physiol |
Title: |
Tuberin regulates the DNA repair enzyme OGG1. |
Volume: |
294 |
Issue: |
1 |
Pages: |
F281-90 |
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Publication |
First Author: |
Trapp C |
Year: |
2007 |
Journal: |
Oncogene |
Title: |
Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice. |
Volume: |
26 |
Issue: |
27 |
Pages: |
4044-8 |
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Publication |
First Author: |
Tsuzuki T |
Year: |
2007 |
Journal: |
Cancer Sci |
Title: |
Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis. |
Volume: |
98 |
Issue: |
4 |
Pages: |
465-70 |
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Publication |
First Author: |
Hu J |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes. |
Volume: |
280 |
Issue: |
49 |
Pages: |
40544-51 |
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Publication |
First Author: |
Saxowsky TT |
Year: |
2008 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells. |
Volume: |
105 |
Issue: |
48 |
Pages: |
18877-82 |
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Publication |
First Author: |
Ba X |
Year: |
2014 |
Journal: |
J Immunol |
Title: |
8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors. |
Volume: |
192 |
Issue: |
5 |
Pages: |
2384-94 |
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Publication |
First Author: |
Noren Hooten N |
Year: |
2011 |
Journal: |
J Biol Chem |
Title: |
Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1). |
Volume: |
286 |
Issue: |
52 |
Pages: |
44679-90 |
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Publication |
First Author: |
Tumurkhuu G |
Year: |
2016 |
Journal: |
Circ Res |
Title: |
Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis. |
Volume: |
119 |
Issue: |
6 |
Pages: |
e76-90 |
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
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•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
•
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Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
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•
•
•
•
|