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Search results 1 to 100 out of 188 for Ogg1

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0.037s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Drosophila melanogaster
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Saccharomyces cerevisiae
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Domain
Type: Family
Description: One of the major base lesions induced by oxidative stress is 8-oxoguanine (8-oxoG), one of the oxidised forms of guanine. 8-oxoguanine DNA glycosylase (also known as N-glycosylase/DNA lyase) functions in base excision repair and is responsible for the excision of 8-oxoguanine. It has beta-lyase activity that nicks DNA 3' to the lesion [, , ].
Publication
First Author: Aburatani H
Year: 1997
Journal: Cancer Res
Title: Cloning and characterization of mammalian 8-hydroxyguanine-specific DNA glycosylase/apurinic, apyrimidinic lyase, a functional mutM homologue.
Volume: 57
Issue: 11
Pages: 2151-6
Publication
First Author: Kovtun IV
Year: 2007
Journal: Nature
Title: OGG1 initiates age-dependent CAG trinucleotide expansion in somatic cells.
Volume: 447
Issue: 7143
Pages: 447-52
Publication  
First Author: Kakehashi A
Year: 2017
Journal: Int J Mol Sci
Title: Enhanced Susceptibility of Ogg1 Mutant Mice to Multiorgan Carcinogenesis.
Volume: 18
Issue: 8
Publication
First Author: van der Kemp PA
Year: 1996
Journal: Proc Natl Acad Sci U S A
Title: Cloning and expression in Escherichia coli of the OGG1 gene of Saccharomyces cerevisiae, which codes for a DNA glycosylase that excises 7,8-dihydro-8-oxoguanine and 2,6-diamino-4-hydroxy-5-N-methylformamidopyrimidine.
Volume: 93
Issue: 11
Pages: 5197-202
Publication
First Author: Yuzefovych LV
Year: 2016
Journal: Cancer Res
Title: Mitochondrial DNA Repair through OGG1 Activity Attenuates Breast Cancer Progression and Metastasis.
Volume: 76
Issue: 1
Pages: 30-4
Publication
First Author: Sakumi K
Year: 2003
Journal: Cancer Res
Title: Ogg1 knockout-associated lung tumorigenesis and its suppression by Mth1 gene disruption.
Volume: 63
Issue: 5
Pages: 902-5
Publication
First Author: Komakula SSB
Year: 2018
Journal: Sci Rep
Title: The DNA Repair Protein OGG1 Protects Against Obesity by Altering Mitochondrial Energetics in White Adipose Tissue.
Volume: 8
Issue: 1
Pages: 14886
Publication
First Author: Kunisada M
Year: 2005
Journal: Cancer Res
Title: 8-Oxoguanine formation induced by chronic UVB exposure makes Ogg1 knockout mice susceptible to skin carcinogenesis.
Volume: 65
Issue: 14
Pages: 6006-10
Publication
First Author: Boiteux S
Year: 1998
Journal: Free Radic Res
Title: Excision repair of 8-hydroxyguanine in mammalian cells: the mouse Ogg1 protein as a model.
Volume: 29
Issue: 6
Pages: 487-97
Publication  
First Author: Chimienti G
Year: 2019
Journal: Int J Mol Sci
Title: Deletion of OGG1 Results in a Differential Signature of Oxidized Purine Base Damage in mtDNA Regions.
Volume: 20
Issue: 13
Publication
First Author: Boiteux S
Year: 2000
Journal: Arch Biochem Biophys
Title: The human OGG1 gene: structure, functions, and its implication in the process of carcinogenesis.
Volume: 377
Issue: 1
Pages: 1-8
Publication
First Author: Lee CJ
Year: 2011
Journal: Toxicol Sci
Title: Resistance of CD-1 and ogg1 DNA repair-deficient mice to thalidomide and hydrolysis product embryopathies in embryo culture.
Volume: 122
Issue: 1
Pages: 146-56
Publication
First Author: Simon H
Year: 2020
Journal: PLoS One
Title: OGG1 deficiency alters the intestinal microbiome and increases intestinal inflammation in a mouse model.
Volume: 15
Issue: 1
Pages: e0227501
Publication
First Author: Tominaga Y
Year: 2004
Journal: Nucleic Acids Res
Title: MUTYH prevents OGG1 or APEX1 from inappropriately processing its substrate or reaction product with its C-terminal domain.
Volume: 32
Issue: 10
Pages: 3198-211
Publication
First Author: Karahalil B
Year: 2003
Journal: J Biol Chem
Title: Compromised incision of oxidized pyrimidines in liver mitochondria of mice deficient in NTH1 and OGG1 glycosylases.
Volume: 278
Issue: 36
Pages: 33701-7
Publication
First Author: Xie Y
Year: 2008
Journal: Carcinogenesis
Title: Cells deficient in oxidative DNA damage repair genes Myh and Ogg1 are sensitive to oxidants with increased G2/M arrest and multinucleation.
Volume: 29
Issue: 4
Pages: 722-8
Publication
First Author: de Souza-Pinto NC
Year: 2009
Journal: Mol Cell Biol
Title: The recombination protein RAD52 cooperates with the excision repair protein OGG1 for the repair of oxidative lesions in mammalian cells.
Volume: 29
Issue: 16
Pages: 4441-54
Publication
First Author: Russo MT
Year: 2004
Journal: Cancer Res
Title: Accumulation of the oxidative base lesion 8-hydroxyguanine in DNA of tumor-prone mice defective in both the Myh and Ogg1 DNA glycosylases.
Volume: 64
Issue: 13
Pages: 4411-4
Publication
First Author: Tani M
Year: 1998
Journal: Mamm Genome
Title: Genomic structure and chromosomal localization of the mouse Ogg1 gene that is involved in the repair of 8-hydroxyguanine in DNA damage.
Volume: 9
Issue: 1
Pages: 32-7
Publication
First Author: Arai T
Year: 2006
Journal: Toxicology
Title: The study using wild-type and Ogg1 knockout mice exposed to potassium bromate shows no tumor induction despite an extensive accumulation of 8-hydroxyguanine in kidney DNA.
Volume: 221
Issue: 2-3
Pages: 179-86
Publication
First Author: Xie Y
Year: 2004
Journal: Cancer Res
Title: Deficiencies in mouse Myh and Ogg1 result in tumor predisposition and G to T mutations in codon 12 of the K-ras oncogene in lung tumors.
Volume: 64
Issue: 9
Pages: 3096-102
Protein
Organism: Mus musculus
Length: 345  
Fragment?: false
Protein
Organism: Mus musculus
Length: 345  
Fragment?: false
Publication
First Author: Nash HM
Year: 1996
Journal: Curr Biol
Title: Cloning of a yeast 8-oxoguanine DNA glycosylase reveals the existence of a base-excision DNA-repair protein superfamily.
Volume: 6
Issue: 8
Pages: 968-80
Publication
First Author: Choi JY
Year: 1999
Journal: Free Radic Biol Med
Title: Thermolabile 8-hydroxyguanine DNA glycosylase with low activity in senescence-accelerated mice due to a single-base mutation.
Volume: 27
Issue: 7-8
Pages: 848-54
Publication
First Author: Rosenquist TA
Year: 1997
Journal: Proc Natl Acad Sci U S A
Title: Cloning and characterization of a mammalian 8-oxoguanine DNA glycosylase.
Volume: 94
Issue: 14
Pages: 7429-34
Publication
First Author: Kinoshita A
Year: 2007
Journal: Cancer Sci
Title: Carcinogenicity of dimethylarsinic acid in Ogg1-deficient mice.
Volume: 98
Issue: 6
Pages: 803-14
Publication
First Author: Arai T
Year: 2003
Journal: Cancer Res
Title: Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA.
Volume: 63
Issue: 14
Pages: 4287-92
Publication
First Author: Arai T
Year: 2002
Journal: Carcinogenesis
Title: High accumulation of oxidative DNA damage, 8-hydroxyguanine, in Mmh/Ogg1 deficient mice by chronic oxidative stress.
Volume: 23
Issue: 12
Pages: 2005-10
Publication
First Author: Klungland A
Year: 1999
Journal: Proc Natl Acad Sci U S A
Title: Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage.
Volume: 96
Issue: 23
Pages: 13300-5
Publication
First Author: de Souza-Pinto NC
Year: 2001
Journal: Cancer Res
Title: Repair of 8-oxodeoxyguanosine lesions in mitochondrial dna depends on the oxoguanine dna glycosylase (OGG1) gene and 8-oxoguanine accumulates in the mitochondrial dna of OGG1-defective mice.
Volume: 61
Issue: 14
Pages: 5378-81
Publication
First Author: Wang W
Year: 2011
Journal: J Neurosci
Title: Mitochondrial DNA damage level determines neural stem cell differentiation fate.
Volume: 31
Issue: 26
Pages: 9746-51
Publication
First Author: Wong AW
Year: 2008
Journal: J Neurosci
Title: Oxoguanine glycosylase 1 protects against methamphetamine-enhanced fetal brain oxidative DNA damage and neurodevelopmental deficits.
Volume: 28
Issue: 36
Pages: 9047-54
Publication
First Author: Rozalski R
Year: 2005
Journal: Int J Biochem Cell Biol
Title: Substantial decrease of urinary 8-oxo-7,8-dihydroguanine, a product of the base excision repair pathway, in DNA glycosylase defective mice.
Volume: 37
Issue: 6
Pages: 1331-6
Publication  
First Author: Scheffler K
Year: 2018
Journal: DNA Repair (Amst)
Title: 8-oxoguanine DNA glycosylase (Ogg1) controls hepatic gluconeogenesis.
Volume: 61
Pages: 56-62
Publication
First Author: Winter DB
Year: 2003
Journal: J Immunol
Title: Normal somatic hypermutation of Ig genes in the absence of 8-hydroxyguanine-DNA glycosylase.
Volume: 170
Issue: 11
Pages: 5558-62
Publication
First Author: Yuzefovych LV
Year: 2013
Journal: Endocrinology
Title: Alteration of mitochondrial function and insulin sensitivity in primary mouse skeletal muscle cells isolated from transgenic and knockout mice: role of ogg1.
Volume: 154
Issue: 8
Pages: 2640-9
Publication
First Author: Cheresh P
Year: 2015
Journal: Am J Respir Cell Mol Biol
Title: Asbestos-induced pulmonary fibrosis is augmented in 8-oxoguanine DNA glycosylase knockout mice.
Volume: 52
Issue: 1
Pages: 25-36
Publication
First Author: Vartanian V
Year: 2017
Journal: PLoS One
Title: 8-oxoguanine DNA glycosylase (OGG1) deficiency elicits coordinated changes in lipid and mitochondrial metabolism in muscle.
Volume: 12
Issue: 7
Pages: e0181687
Publication
First Author: Yogianti F
Year: 2014
Journal: J Invest Dermatol
Title: Inhibitory effects of dietary Spirulina platensis on UVB-induced skin inflammatory responses and carcinogenesis.
Volume: 134
Issue: 10
Pages: 2610-2619
Publication
First Author: Kunisada M
Year: 2011
Journal: Am J Pathol
Title: Increased expression of versican in the inflammatory response to UVB- and reactive oxygen species-induced skin tumorigenesis.
Volume: 179
Issue: 6
Pages: 3056-65
Publication
First Author: Sampath H
Year: 2012
Journal: PLoS One
Title: 8-Oxoguanine DNA glycosylase (OGG1) deficiency increases susceptibility to obesity and metabolic dysfunction.
Volume: 7
Issue: 12
Pages: e51697
Publication
First Author: Mori M
Year: 2001
Journal: Free Radic Biol Med
Title: Spontaneous loss-of-function mutations of the 8-oxoguanine DNA glycosylase gene in mice and exploration of the possible implication of the gene in senescence.
Volume: 30
Issue: 10
Pages: 1130-6
Publication
First Author: Conlon KA
Year: 2004
Journal: DNA Repair (Amst)
Title: Cell cycle regulation of the murine 8-oxoguanine DNA glycosylase (mOGG1): mOGG1 associates with microtubules during interphase and mitosis.
Volume: 3
Issue: 12
Pages: 1601-15
Publication
First Author: Bhakat KK
Year: 2006
Journal: Mol Cell Biol
Title: Acetylation of human 8-oxoguanine-DNA glycosylase by p300 and its role in 8-oxoguanine repair in vivo.
Volume: 26
Issue: 5
Pages: 1654-65
Publication
First Author: Wu M
Year: 2011
Journal: Infect Immun
Title: Host DNA repair proteins in response to Pseudomonas aeruginosa in lung epithelial cells and in mice.
Volume: 79
Issue: 1
Pages: 75-87
Publication
First Author: Ondovcik SL
Year: 2012
Journal: Toxicol Sci
Title: Oxoguanine glycosylase 1 (OGG1) protects cells from DNA double-strand break damage following methylmercury (MeHg) exposure.
Volume: 128
Issue: 1
Pages: 272-83
Publication  
First Author: Aguilera-Aguirre L
Year: 2015
Journal: Free Radic Biol Med
Title: Whole transcriptome analysis reveals an 8-oxoguanine DNA glycosylase-1-driven DNA repair-dependent gene expression linked to essential biological processes.
Volume: 81
Pages: 107-18
Publication
First Author: Hansen SH
Year: 2010
Journal: Mutat Res
Title: In vitro investigations of glycidamide-induced DNA lesions in mouse male germ cells and in mouse and human lymphocytes.
Volume: 696
Issue: 1
Pages: 55-61
Publication
First Author: Wang Z
Year: 2010
Journal: PLoS Genet
Title: Characterization of oxidative guanine damage and repair in mammalian telomeres.
Volume: 6
Issue: 5
Pages: e1000951
Publication
First Author: Pao PC
Year: 2020
Journal: Nat Commun
Title: HDAC1 modulates OGG1-initiated oxidative DNA damage repair in the aging brain and Alzheimer's disease.
Volume: 11
Issue: 1
Pages: 2484
Publication
First Author: Jałoszyński P
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Dysfunction of Nrf2 decreases KBrO3-induced oxidative DNA damage in Ogg1-null mice.
Volume: 364
Issue: 4
Pages: 966-71
Publication
First Author: Trapp C
Year: 2007
Journal: Oncogene
Title: Deficiency of the Cockayne syndrome B (CSB) gene aggravates the genomic instability caused by endogenous oxidative DNA base damage in mice.
Volume: 26
Issue: 27
Pages: 4044-8
Publication  
First Author: Jalland CM
Year: 2014
Journal: Free Radic Biol Med
Title: Accelerated clinical course of prion disease in mice compromised in repair of oxidative DNA damage.
Volume: 68
Pages: 1-7
Publication
First Author: Osterod M
Year: 2001
Journal: Carcinogenesis
Title: Age-related and tissue-specific accumulation of oxidative DNA base damage in 7,8-dihydro-8-oxoguanine-DNA glycosylase (Ogg1) deficient mice.
Volume: 22
Issue: 9
Pages: 1459-63
Publication
First Author: Ye Y
Year: 2017
Journal: J Immunol
Title: DNA Repair Interacts with Autophagy To Regulate Inflammatory Responses to Pulmonary Hyperoxia.
Volume: 198
Issue: 7
Pages: 2844-2853
Publication
First Author: Trapp C
Year: 2007
Journal: Mutat Res
Title: The basal levels of 8-oxoG and other oxidative modifications in intact mitochondrial DNA are low even in repair-deficient (Ogg1(-/-)/Csb(-/-)) mice.
Volume: 625
Issue: 1-2
Pages: 155-63
Publication
First Author: Kauppila JHK
Year: 2018
Journal: Nucleic Acids Res
Title: Base-excision repair deficiency alone or combined with increased oxidative stress does not increase mtDNA point mutations in mice.
Volume: 46
Issue: 13
Pages: 6642-6669
Publication
First Author: Habib SL
Year: 2008
Journal: Am J Physiol Renal Physiol
Title: Tuberin regulates the DNA repair enzyme OGG1.
Volume: 294
Issue: 1
Pages: F281-90
Publication
First Author: Tsuzuki T
Year: 2007
Journal: Cancer Sci
Title: Significance of error-avoiding mechanisms for oxidative DNA damage in carcinogenesis.
Volume: 98
Issue: 4
Pages: 465-70
Publication
First Author: Sheng Z
Year: 2012
Journal: J Clin Invest
Title: 8-Oxoguanine causes neurodegeneration during MUTYH-mediated DNA base excision repair.
Volume: 122
Issue: 12
Pages: 4344-61
Publication
First Author: Hu J
Year: 2005
Journal: J Biol Chem
Title: Repair of formamidopyrimidines in DNA involves different glycosylases: role of the OGG1, NTH1, and NEIL1 enzymes.
Volume: 280
Issue: 49
Pages: 40544-51
Publication
First Author: Saxowsky TT
Year: 2008
Journal: Proc Natl Acad Sci U S A
Title: 8-Oxoguanine-mediated transcriptional mutagenesis causes Ras activation in mammalian cells.
Volume: 105
Issue: 48
Pages: 18877-82
Publication
First Author: Ba X
Year: 2014
Journal: J Immunol
Title: 8-oxoguanine DNA glycosylase-1 augments proinflammatory gene expression by facilitating the recruitment of site-specific transcription factors.
Volume: 192
Issue: 5
Pages: 2384-94
Publication
First Author: Tumurkhuu G
Year: 2016
Journal: Circ Res
Title: Ogg1-Dependent DNA Repair Regulates NLRP3 Inflammasome and Prevents Atherosclerosis.
Volume: 119
Issue: 6
Pages: e76-90
Publication
First Author: Noren Hooten N
Year: 2011
Journal: J Biol Chem
Title: Poly(ADP-ribose) polymerase 1 (PARP-1) binds to 8-oxoguanine-DNA glycosylase (OGG1).
Volume: 286
Issue: 52
Pages: 44679-90
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Lu R
Year: 1997
Journal: Curr Biol
Title: A mammalian DNA repair enzyme that excises oxidatively damaged guanines maps to a locus frequently lost in lung cancer.
Volume: 7
Issue: 6
Pages: 397-407
Publication
First Author: Minowa O
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice.
Volume: 97
Issue: 8
Pages: 4156-61
Publication
First Author: Mabley JG
Year: 2005
Journal: FASEB J
Title: Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation.
Volume: 19
Issue: 2
Pages: 290-2
Publication  
First Author: Miller-Pinsler L
Year: 2015
Journal: Free Radic Biol Med
Title: Oxidative DNA damage in the in utero initiation of postnatal neurodevelopmental deficits by normal fetal and ethanol-enhanced oxidative stress in oxoguanine glycosylase 1 knockout mice.
Volume: 78
Pages: 23-9
Publication  
First Author: Graupner A
Year: 2016
Journal: Sci Rep
Title: Gamma radiation at a human relevant low dose rate is genotoxic in mice.
Volume: 6
Pages: 32977
Publication
First Author: Stuart JA
Year: 2005
Journal: Free Radic Biol Med
Title: No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA.
Volume: 38
Issue: 6
Pages: 737-45
Publication
First Author: Akatsuka S
Year: 2006
Journal: Am J Pathol
Title: Contrasting genome-wide distribution of 8-hydroxyguanine and acrolein-modified adenine during oxidative stress-induced renal carcinogenesis.
Volume: 169
Issue: 4
Pages: 1328-42
Publication
First Author: Takeda T
Year: 1981
Journal: Mech Ageing Dev
Title: A new murine model of accelerated senescence.
Volume: 17
Issue: 2
Pages: 183-94