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Search results 1 to 100 out of 300 for Orai1

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0.065s
Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: chicken
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Publication
First Author: Vandenberghe M
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: ORAI1 calcium channel orchestrates skin homeostasis.
Volume: 110
Issue: 50
Pages: E4839-48
Publication
First Author: Sogkas G
Year: 2015
Journal: Eur J Immunol
Title: Orai1 controls C5a-induced neutrophil recruitment in inflammation.
Volume: 45
Issue: 7
Pages: 2143-53
Publication
First Author: Bergmeier W
Year: 2009
Journal: Blood
Title: R93W mutation in Orai1 causes impaired calcium influx in platelets.
Volume: 113
Issue: 3
Pages: 675-8
Publication
First Author: Robinson LJ
Year: 2021
Journal: FASEB J
Title: The function of the calcium channel Orai1 in osteoclast development.
Volume: 35
Issue: 6
Pages: e21653
Publication
First Author: Moon H
Year: 2020
Journal: Nat Commun
Title: Crbn modulates calcium influx by regulating Orai1 during efferocytosis.
Volume: 11
Issue: 1
Pages: 5489
Publication
First Author: Bhavsar SK
Year: 2013
Journal: Cell Physiol Biochem
Title: AMPKα1-sensitivity of Orai1 and Ca(2+) entry in T - lymphocytes.
Volume: 32
Issue: 3
Pages: 687-98
Publication
First Author: Zhao X
Year: 2012
Journal: PLoS One
Title: Orai1 mediates exacerbated Ca(2+) entry in dystrophic skeletal muscle.
Volume: 7
Issue: 11
Pages: e49862
Publication
First Author: Davis FM
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Essential role of Orai1 store-operated calcium channels in lactation.
Volume: 112
Issue: 18
Pages: 5827-32
Publication
First Author: Zhou Y
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: Pore architecture of the ORAI1 store-operated calcium channel.
Volume: 107
Issue: 11
Pages: 4896-901
Publication
First Author: Novakovic MM
Year: 2023
Journal: Nat Commun
Title: Astrocyte reactivity and inflammation-induced depression-like behaviors are regulated by Orai1 calcium channels.
Volume: 14
Issue: 1
Pages: 5500
Publication
First Author: Braun A
Year: 2009
Journal: Blood
Title: Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation.
Volume: 113
Issue: 9
Pages: 2056-63
Publication
First Author: Greenberg ML
Year: 2013
Journal: J Immunol
Title: Orai1 function is essential for T cell homing to lymph nodes.
Volume: 190
Issue: 7
Pages: 3197-206
Publication  
First Author: Segin S
Year: 2020
Journal: Cells
Title: Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling.
Volume: 9
Issue: 5
Publication    
First Author: Emrich SM
Year: 2023
Journal: Elife
Title: Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells.
Volume: 12
Publication
First Author: Dou Y
Year: 2018
Journal: J Neurosci
Title: Orai1 Plays a Crucial Role in Central Sensitization by Modulating Neuronal Excitability.
Volume: 38
Issue: 4
Pages: 887-900
Publication
First Author: Völkers M
Year: 2012
Journal: J Cell Sci
Title: Orai1 deficiency leads to heart failure and skeletal myopathy in zebrafish.
Volume: 125
Issue: Pt 2
Pages: 287-94
Publication
First Author: Kim KD
Year: 2011
Journal: J Immunol
Title: ORAI1 deficiency impairs activated T cell death and enhances T cell survival.
Volume: 187
Issue: 7
Pages: 3620-30
Publication
First Author: Michaelis M
Year: 2015
Journal: Glia
Title: STIM1, STIM2, and Orai1 regulate store-operated calcium entry and purinergic activation of microglia.
Volume: 63
Issue: 4
Pages: 652-63
Publication
First Author: McCarl CA
Year: 2010
Journal: J Immunol
Title: Store-operated Ca2+ entry through ORAI1 is critical for T cell-mediated autoimmunity and allograft rejection.
Volume: 185
Issue: 10
Pages: 5845-58
Publication
First Author: Desai PN
Year: 2015
Journal: Sci Signal
Title: Multiple types of calcium channels arising from alternative translation initiation of the Orai1 message.
Volume: 8
Issue: 387
Pages: ra74
Publication
First Author: Schaff UY
Year: 2010
Journal: Blood
Title: Orai1 regulates intracellular calcium, arrest, and shape polarization during neutrophil recruitment in shear flow.
Volume: 115
Issue: 3
Pages: 657-66
Publication
First Author: Lee SH
Year: 2016
Journal: Biochem Biophys Res Commun
Title: Orai1 mediates osteogenic differentiation via BMP signaling pathway in bone marrow mesenchymal stem cells.
Volume: 473
Issue: 4
Pages: 1309-1314
Publication
First Author: Maciąg F
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Res
Title: Behavioral and electrophysiological changes in female mice overexpressing ORAI1 in neurons.
Volume: 1866
Issue: 7
Pages: 1137-1150
Publication
First Author: Xing J
Year: 2014
Journal: J Physiol
Title: Role of Orai1 and store-operated calcium entry in mouse lacrimal gland signalling and function.
Volume: 592
Issue: 5
Pages: 927-39
Publication
First Author: Liang SJ
Year: 2016
Journal: Arterioscler Thromb Vasc Biol
Title: Inhibition of Orai1 Store-Operated Calcium Channel Prevents Foam Cell Formation and Atherosclerosis.
Volume: 36
Issue: 4
Pages: 618-28
Publication
First Author: Bartoli F
Year: 2020
Journal: Circulation
Title: Orai1 Channel Inhibition Preserves Left Ventricular Systolic Function and Normal Ca2+ Handling After Pressure Overload.
Volume: 141
Issue: 3
Pages: 199-216
Publication
First Author: Kim JH
Year: 2021
Journal: Nat Commun
Title: Insulin-activated store-operated Ca2+ entry via Orai1 induces podocyte actin remodeling and causes proteinuria.
Volume: 12
Issue: 1
Pages: 6537
Publication
First Author: Zheng L
Year: 2015
Journal: Dev Dyn
Title: Orai1 expression pattern in tooth and craniofacial ectodermal tissues and potential functions during ameloblast differentiation.
Volume: 244
Issue: 10
Pages: 1249-58
Publication
First Author: Wang YH
Year: 2022
Journal: Sci Adv
Title: Distinct roles of ORAI1 in T cell-mediated allergic airway inflammation and immunity to influenza A virus infection.
Volume: 8
Issue: 40
Pages: eabn6552
Publication
First Author: Horton JS
Year: 2014
Journal: Channels (Austin)
Title: The calcium release-activated calcium channel Orai1 represents a crucial component in hypertrophic compensation and the development of dilated cardiomyopathy.
Volume: 8
Issue: 1
Pages: 35-48
Publication
First Author: Takahashi Y
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry.
Volume: 356
Issue: 1
Pages: 45-52
Publication
First Author: Grimes D
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense.
Volume: 117
Issue: 39
Pages: 24403-24414
Publication
First Author: Sabourin J
Year: 2015
Journal: J Biol Chem
Title: Store-operated Ca2+ Entry Mediated by Orai1 and TRPC1 Participates to Insulin Secretion in Rat β-Cells.
Volume: 290
Issue: 51
Pages: 30530-9
Publication
First Author: Maruyama Y
Year: 2009
Journal: J Biol Chem
Title: Tetrameric Orai1 is a teardrop-shaped molecule with a long, tapered cytoplasmic domain.
Volume: 284
Issue: 20
Pages: 13676-85
Publication
First Author: Robinson LJ
Year: 2012
Journal: Lab Invest
Title: Gene disruption of the calcium channel Orai1 results in inhibition of osteoclast and osteoblast differentiation and impairs skeletal development.
Volume: 92
Issue: 7
Pages: 1071-83
Publication
First Author: Carrell EM
Year: 2016
Journal: FASEB J
Title: Orai1 enhances muscle endurance by promoting fatigue-resistant type I fiber content but not through acute store-operated Ca2+ entry.
Volume: 30
Issue: 12
Pages: 4109-4119
Publication
First Author: Kim KD
Year: 2014
Journal: J Immunol
Title: Calcium signaling via Orai1 is essential for induction of the nuclear orphan receptor pathway to drive Th17 differentiation.
Volume: 192
Issue: 1
Pages: 110-22
Publication
First Author: Cross BM
Year: 2013
Journal: PLoS One
Title: SPCA2 regulates Orai1 trafficking and store independent Ca2+ entry in a model of lactation.
Volume: 8
Issue: 6
Pages: e67348
Publication
First Author: Maneshi MM
Year: 2020
Journal: Cell Rep
Title: Orai1 Channels Are Essential for Amplification of Glutamate-Evoked Ca2+ Signals in Dendritic Spines to Regulate Working and Associative Memory.
Volume: 33
Issue: 9
Pages: 108464
Publication
First Author: Gilio K
Year: 2010
Journal: J Biol Chem
Title: Roles of platelet STIM1 and Orai1 in glycoprotein VI- and thrombin-dependent procoagulant activity and thrombus formation.
Volume: 285
Issue: 31
Pages: 23629-38
Publication
First Author: Gómez-Fernández C
Year: 2012
Journal: Mol Hum Reprod
Title: Calcium signaling in mouse oocyte maturation: the roles of STIM1, ORAI1 and SOCE.
Volume: 18
Issue: 4
Pages: 194-203
Publication
First Author: Jardin I
Year: 2008
Journal: J Biol Chem
Title: Orai1 mediates the interaction between STIM1 and hTRPC1 and regulates the mode of activation of hTRPC1-forming Ca2+ channels.
Volume: 283
Issue: 37
Pages: 25296-25304
Publication
First Author: Kaufmann U
Year: 2016
Journal: J Immunol
Title: Selective ORAI1 Inhibition Ameliorates Autoimmune Central Nervous System Inflammation by Suppressing Effector but Not Regulatory T Cell Function.
Volume: 196
Issue: 2
Pages: 573-85
Publication
First Author: Noy PJ
Year: 2019
Journal: Haematologica
Title: Tspan18 is a novel regulator of the Ca2+ channel Orai1 and von Willebrand factor release in endothelial cells.
Volume: 104
Issue: 9
Pages: 1892-1905
Publication
First Author: Ávila-Medina J
Year: 2016
Journal: J Biol Chem
Title: Orai1 and TRPC1 Proteins Co-localize with CaV1.2 Channels to Form a Signal Complex in Vascular Smooth Muscle Cells.
Volume: 291
Issue: 40
Pages: 21148-21159
Publication
First Author: Choi D
Year: 2017
Journal: Circ Res
Title: ORAI1 Activates Proliferation of Lymphatic Endothelial Cells in Response to Laminar Flow Through Krüppel-Like Factors 2 and 4.
Volume: 120
Issue: 9
Pages: 1426-1439
Publication
First Author: Gross SA
Year: 2007
Journal: J Biol Chem
Title: Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels.
Volume: 282
Issue: 27
Pages: 19375-84
Publication
First Author: Yang B
Year: 2012
Journal: Am J Physiol Cell Physiol
Title: Orai1 and Ca2+-independent phospholipase A2 are required for store-operated Icat-SOC current, Ca2+ entry, and proliferation of primary vascular smooth muscle cells.
Volume: 302
Issue: 5
Pages: C748-56
Publication    
First Author: Michelucci A
Year: 2019
Journal: Elife
Title: Transverse tubule remodeling enhances Orai1-dependent Ca2+ entry in skeletal muscle.
Volume: 8
Publication
First Author: Ahuja M
Year: 2017
Journal: Cell Metab
Title: Orai1-Mediated Antimicrobial Secretion from Pancreatic Acini Shapes the Gut Microbiome and Regulates Gut Innate Immunity.
Volume: 25
Issue: 3
Pages: 635-646
Publication
First Author: Davis FM
Year: 2016
Journal: Cell Calcium
Title: Male infertility in mice lacking the store-operated Ca(2+) channel Orai1.
Volume: 59
Issue: 4
Pages: 189-97
Protein
Organism: Mus musculus/domesticus
Length: 304  
Fragment?: false
Publication  
First Author: Yang L
Year: 2022
Journal: Cells
Title: Reduction in SOCE and Associated Aggregation in Platelets from Mice with Platelet-Specific Deletion of Orai1.
Volume: 11
Issue: 20
Publication
First Author: Gwack Y
Year: 2008
Journal: Mol Cell Biol
Title: Hair loss and defective T- and B-cell function in mice lacking ORAI1.
Volume: 28
Issue: 17
Pages: 5209-22
Publication
First Author: Darbellay B
Year: 2014
Journal: J Invest Dermatol
Title: Reversal of murine epidermal atrophy by topical modulation of calcium signaling.
Volume: 134
Issue: 6
Pages: 1599-1608
Publication  
First Author: Majewski L
Year: 2019
Journal: Int J Mol Sci
Title: Changes in Calcium Homeostasis and Gene Expression Implicated in Epilepsy in Hippocampi of Mice Overexpressing ORAI1.
Volume: 20
Issue: 22
Publication
First Author: Zeng B
Year: 2017
Journal: Nat Commun
Title: ORAI channels are critical for receptor-mediated endocytosis of albumin.
Volume: 8
Issue: 1
Pages: 1920
Publication
First Author: Nascimento Da Conceicao V
Year: 2021
Journal: iScience
Title: Resolving macrophage polarization through distinct Ca2+ entry channel that maintains intracellular signaling and mitochondrial bioenergetics.
Volume: 24
Issue: 11
Pages: 103339
Publication
First Author: Lee B
Year: 2013
Journal: J Cell Sci
Title: Downregulation of store-operated Ca2+ entry during mammalian meiosis is required for the egg-to-embryo transition.
Volume: 126
Issue: Pt 7
Pages: 1672-81
Publication  
First Author: Eckstein M
Year: 2019
Journal: Sci Signal
Title: Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.
Volume: 12
Issue: 578
Publication
First Author: Maus M
Year: 2017
Journal: Cell Metab
Title: Store-Operated Ca2+ Entry Controls Induction of Lipolysis and the Transcriptional Reprogramming to Lipid Metabolism.
Volume: 25
Issue: 3
Pages: 698-712
Publication
First Author: Chen W
Year: 2014
Journal: J Thromb Haemost
Title: Orai1-induced store-operated Ca(2+) entry enhances phospholipase activity and modulates canonical transient receptor potential channel 6 function in murine platelets.
Volume: 12
Issue: 4
Pages: 528-39
Publication
First Author: Somasundaram A
Year: 2014
Journal: J Neurosci
Title: Store-operated CRAC channels regulate gene expression and proliferation in neural progenitor cells.
Volume: 34
Issue: 27
Pages: 9107-23
Publication  
First Author: Toth AB
Year: 2019
Journal: Sci Signal
Title: CRAC channels regulate astrocyte Ca2+ signaling and gliotransmitter release to modulate hippocampal GABAergic transmission.
Volume: 12
Issue: 582
Publication
First Author: Dixit N
Year: 2011
Journal: J Immunol
Title: Migrational guidance of neutrophils is mechanotransduced via high-affinity LFA-1 and calcium flux.
Volume: 187
Issue: 1
Pages: 472-81
Publication
First Author: Henke N
Year: 2012
Journal: J Biol Chem
Title: Stromal interaction molecule 1 (STIM1) is involved in the regulation of mitochondrial shape and bioenergetics and plays a role in oxidative stress.
Volume: 287
Issue: 50
Pages: 42042-52
Publication
First Author: El Hachmane MF
Year: 2018
Journal: Biochem J
Title: Extracellular ATP activates store-operated Ca2+ entry in white adipocytes: functional evidence for STIM1 and ORAI1.
Volume: 475
Issue: 3
Pages: 691-704
Publication  
First Author: Vaeth M
Year: 2017
Journal: Nat Commun
Title: ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.
Volume: 8
Pages: 14714
Publication
First Author: Waite JC
Year: 2013
Journal: Eur J Immunol
Title: Interference with Ca(2+) release activated Ca(2+) (CRAC) channel function delays T-cell arrest in vivo.
Volume: 43
Issue: 12
Pages: 3343-54
Publication
First Author: Goonasekera SA
Year: 2014
Journal: Hum Mol Genet
Title: Enhanced Ca²⁺ influx from STIM1-Orai1 induces muscle pathology in mouse models of muscular dystrophy.
Volume: 23
Issue: 14
Pages: 3706-15
Publication
First Author: Dixit N
Year: 2012
Journal: J Immunol
Title: Leukocyte function antigen-1, kindlin-3, and calcium flux orchestrate neutrophil recruitment during inflammation.
Volume: 189
Issue: 12
Pages: 5954-64
Publication
First Author: Srikanth S
Year: 2010
Journal: Nat Cell Biol
Title: A novel EF-hand protein, CRACR2A, is a cytosolic Ca2+ sensor that stabilizes CRAC channels in T cells.
Volume: 12
Issue: 5
Pages: 436-46
Publication
First Author: Hwang SY
Year: 2012
Journal: FASEB J
Title: Orai1-mediated calcium entry plays a critical role in osteoclast differentiation and function by regulating activation of the transcription factor NFATc1.
Volume: 26
Issue: 4
Pages: 1484-92
Publication
First Author: Usui R
Year: 2019
Journal: Sci Rep
Title: GPR40 activation initiates store-operated Ca2+ entry and potentiates insulin secretion via the IP3R1/STIM1/Orai1 pathway in pancreatic β-cells.
Volume: 9
Issue: 1
Pages: 15562
Publication
First Author: Lyfenko AD
Year: 2008
Journal: J Physiol
Title: Differential dependence of store-operated and excitation-coupled Ca2+ entry in skeletal muscle on STIM1 and Orai1.
Volume: 586
Issue: 20
Pages: 4815-24
Publication
First Author: Edwards JN
Year: 2010
Journal: Am J Physiol Cell Physiol
Title: Upregulation of store-operated Ca2+ entry in dystrophic mdx mouse muscle.
Volume: 299
Issue: 1
Pages: C42-50
Publication
First Author: Shaw PJ
Year: 2014
Journal: J Clin Invest
Title: CD4⁺ and CD8⁺ T cell-dependent antiviral immunity requires STIM1 and STIM2.
Volume: 124
Issue: 10
Pages: 4549-63
Publication
First Author: Lur G
Year: 2011
Journal: Biochem J
Title: InsP₃receptors and Orai channels in pancreatic acinar cells: co-localization and its consequences.
Volume: 436
Issue: 2
Pages: 231-9
Publication
First Author: Choi D
Year: 2017
Journal: J Clin Invest
Title: Laminar flow downregulates Notch activity to promote lymphatic sprouting.
Volume: 127
Issue: 4
Pages: 1225-1240
Publication  
First Author: Diercks BP
Year: 2018
Journal: Sci Signal
Title: ORAI1, STIM1/2, and RYR1 shape subsecond Ca2+ microdomains upon T cell activation.
Volume: 11
Issue: 561
Publication
First Author: Shanmughapriya S
Year: 2015
Journal: Sci Signal
Title: Ca2+ signals regulate mitochondrial metabolism by stimulating CREB-mediated expression of the mitochondrial Ca2+ uniporter gene MCU.
Volume: 8
Issue: 366
Pages: ra23
Publication
First Author: Concepcion AR
Year: 2016
Journal: J Clin Invest
Title: Store-operated Ca2+ entry regulates Ca2+-activated chloride channels and eccrine sweat gland function.
Volume: 126
Issue: 11
Pages: 4303-4318
Publication
First Author: Núñez L
Year: 2019
Journal: Biochim Biophys Acta Mol Cell Res
Title: Store-operated Ca2+ entry and Ca2+ responses to hypothalamic releasing hormones in anterior pituitary cells from Orai1-/- and heptaTRPC knockout mice.
Volume: 1866
Issue: 7
Pages: 1124-1136
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory