|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 84 out of 84 for Orai3

0.019s

Categories

Hits by Category

Hits by Strain

Type Details Score
Gene
93129 | ORAI3
Type: gene
Organism: human
•
•
•
•
•
Gene
309000 | Orai3
Type: gene
Organism: rat
•
•
•
•
•
Gene
607303 | ORAI3
Type: gene
Organism: dog, domestic
•
•
•
•
•
Gene
454057 | ORAI3
Type: gene
Organism: chimpanzee
•
•
•
•
•
Gene
515971 | ORAI3
Type: gene
Organism: cattle
•
•
•
•
•
Gene
712360 | ORAI3
Type: gene
Organism: macaque, rhesus
•
•
•
•
•
Protein Coding Gene
MGI:3039586 | Orai3
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Publication
35861698 | J:345029
 
First Author: Wang L
Year: 2022
Journal: J Gen Physiol
Title: ORAI3 is dispensable for store-operated Ca2+ entry and immune responses by lymphocytes and macrophages.
Volume: 154
Issue: 10
•
•
•
•
•
Publication
33849280 | J:345532
First Author: Gammons J
Year: 2021
Journal: J Am Heart Assoc
Title: Cardiac-Specific Deletion of Orai3 Leads to Severe Dilated Cardiomyopathy and Heart Failure in Mice.
Volume: 10
Issue: 8
Pages: e019486
•
•
•
•
•
Publication
36803766 | J:345485
   
First Author: Emrich SM
Year: 2023
Journal: Elife
Title: Orai3 and Orai1 mediate CRAC channel function and metabolic reprogramming in B cells.
Volume: 12
•
•
•
•
•
Publication
17463004 | J:123525
First Author: Gross SA
Year: 2007
Journal: J Biol Chem
Title: Murine ORAI2 splice variants form functional Ca2+ release-activated Ca2+ (CRAC) channels.
Volume: 282
Issue: 27
Pages: 19375-84
•
•
•
•
•
Publication
17343823 | J:121458
First Author: Takahashi Y
Year: 2007
Journal: Biochem Biophys Res Commun
Title: Essential role of the N-terminus of murine Orai1 in store-operated Ca2+ entry.
Volume: 356
Issue: 1
Pages: 45-52
•
•
•
•
•
Protein Coding Gene
MGP_CAROLIEiJ_G0030518 | -
Type: protein_coding_gene
Organism: Mus caroli
•
•
•
•
•
Protein Coding Gene
MGP_129S1SvImJ_G0033052 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AJ_G0033035 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_AKRJ_G0032967 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_BALBcJ_G0033036 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C3HHeJ_G0032750 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGI_C57BL6J_3039586 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_C57BL6NJ_G0033545 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CASTEiJ_G0032079 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_CBAJ_G0032723 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_DBA2J_G0032875 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_FVBNJ_G0032828 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_LPJ_G0032969 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NODShiLtJ_G0032860 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_NZOHlLtJ_G0033565 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PWKPhJ_G0031786 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_WSBEiJ_G0032191 | -
Type: protein_coding_gene
Organism: mouse, laboratory
•
•
•
•
•
Protein Coding Gene
MGP_PahariEiJ_G0013725 | -
Type: protein_coding_gene
Organism: Mus pahari
•
•
•
•
•
Protein Coding Gene
MGP_SPRETEiJ_G0031632 | -
Type: protein_coding_gene
Organism: Mus spretus
•
•
•
•
•
Publication
18059270 | J:130479
First Author: Vig M
Year: 2008
Journal: Nat Immunol
Title: Defective mast cell effector functions in mice lacking the CRACM1 pore subunit of store-operated calcium release-activated calcium channels.
Volume: 9
Issue: 1
Pages: 89-96
•
•
•
•
•
Publication
26764049 | J:235707
First Author: Demaurex N
Year: 2016
Journal: Am J Physiol Cell Physiol
Title: The role of STIM and ORAI proteins in phagocytic immune cells.
Volume: 310
Issue: 7
Pages: C496-508
•
•
•
•
•
Protein
A3KCG3
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
•
•
•
•
•
Publication
28294127 | J:241365
 
First Author: Vaeth M
Year: 2017
Journal: Nat Commun
Title: ORAI2 modulates store-operated calcium entry and T cell-mediated immunity.
Volume: 8
Pages: 14714
•
•
•
•
•
Publication
- | J:265051
     
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
•
•
•
•
•
Publication
- | J:148605
     
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
•
•
•
•
•
Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
•
•
•
•
•
Publication
18799693 | J:142754
First Author: Hansen GM
Year: 2008
Journal: Genome Res
Title: Large-scale gene trapping in C57BL/6N mouse embryonic stem cells.
Volume: 18
Issue: 10
Pages: 1670-9
•
•
•
•
•
Publication
- | J:342604
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt
•
•
•
•
•
Publication
- | J:85000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2003
Title: MGI Sequence Curation Reference
•
•
•
•
•
Publication
- | J:78475
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
•
•
•
•
•
Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
•
•
•
•
•
Publication
38355793 | J:345621
First Author: Adams DJ
Year: 2024
Journal: Nature
Title: Genetic determinants of micronucleus formation in vivo.
Volume: 627
Issue: 8002
Pages: 130-136
•
•
•
•
•
Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
•
•
•
•
•
Publication
14610273 | J:86696
First Author: Zambrowicz BP
Year: 2003
Journal: Proc Natl Acad Sci U S A
Title: Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention.
Volume: 100
Issue: 24
Pages: 14109-14
•
•
•
•
•
Publication
21677750 | J:173534
First Author: Skarnes WC
Year: 2011
Journal: Nature
Title: A conditional knockout resource for the genome-wide study of mouse gene function.
Volume: 474
Issue: 7351
Pages: 337-42
•
•
•
•
•
Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
•
•
•
•
•
Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
•
•
•
•
•
Publication
- | J:60000
       
First Author: UniProt-GOA
Year: 2012
Title: Gene Ontology annotation based on UniProtKB/Swiss-Prot keyword mapping
•
•
•
•
•
Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
•
•
•
•
•
Publication
- | J:164563
       
First Author: The Gene Ontology Consortium
Year: 2010
Title: Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs
•
•
•
•
•
Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
•
•
•
•
•
Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
•
•
•
•
•
Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
•
•
•
•
•
Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
•
•
•
•
•
Publication
- | J:144086
     
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
•
•
•
•
•
Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
•
•
•
•
•
Publication
- | J:85324
     
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
•
•
•
•
•
Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
•
•
•
•
•
Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
•
•
•
•
•
Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
•
•
•
•
•
Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
•
•
•
•
•
Publication
17452328 | -
First Author: DeHaven WI
Year: 2007
Journal: J Biol Chem
Title: Calcium inhibition and calcium potentiation of Orai1, Orai2, and Orai3 calcium release-activated calcium channels.
Volume: 282
Issue: 24
Pages: 17548-56
•
•
•
•
•
Protein Domain
IPR030032 | Orai-3
Type: Family
Description: Orai1 is a pore-forming calcium release-activated calcium (CRAC) channel subunit composed of four transmembrane domains []. Paralogues Orai2 and Orai3 have also been shown to be capable of forming CRAC channels and share Orai1 membrane topology. In these experiments, Orai-1, -2, and -3 channels were similarly inhibited by extracellular Ca2+. Orai3 channels seems to differ from Orai1 and -2 inbeing relatively resistant to the process of Ca2+ depotentiation []. However, the physiological roles of Orai2 and Orai3 in vivo are currently not well understood [].This entry represents Orai3.
•
•
•
•
•
Protein Domain
IPR030034 | Orai-2
Type: Family
Description: Orai1 is a pore-forming calcium release-activated calcium (CRAC) channel subunit composed of four transmembrane domains []. Paralogues Orai2 and Orai3 have also been shown to be capable of forming CRAC channels and share Orai1 membrane topology. In these experiments, Orai-1, -2, and -3 channels were similarly inhibited by extracellular Ca2+. Orai3 channels seems to differ from Orai1 and -2 in being relatively resistant to the process of Ca2+ depotentiation []. However, the physiological roles of Orai2 and Orai3 in vivo are currently not well understood [].This entry represents Orai2.
•
•
•
•
•
Publication
23890118 | -
 
First Author: Hoth M
Year: 2013
Journal: Curr Top Membr
Title: The neglected CRAC proteins: Orai2, Orai3, and STIM2.
Volume: 71
Pages: 237-71
•
•
•
•
•
Publication
20534587 | -
First Author: Kawasaki T
Year: 2010
Journal: J Biol Chem
Title: Protein kinase C-induced phosphorylation of Orai1 regulates the intracellular Ca2+ level via the store-operated Ca2+ channel.
Volume: 285
Issue: 33
Pages: 25720-30
•
•
•
•
•
Protein
Q8BH10
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
•
•
•
•
•
Protein
Q6P8G8
Organism: Mus musculus/domesticus
Length: 290  
Fragment?: false
•
•
•
•
•
Protein
A3KCG2
Organism: Mus musculus/domesticus
Length: 245  
Fragment?: false
•
•
•
•
•
Protein
D3YX58
Organism: Mus musculus/domesticus
Length: 176  
Fragment?: false
•
•
•
•
•
Protein
A0A0G2JFL5
Organism: Mus musculus/domesticus
Length: 158  
Fragment?: true
•
•
•
•
•
Protein
D3Z6X8
Organism: Mus musculus/domesticus
Length: 136  
Fragment?: false
•
•
•
•
•
Protein
Q14BR6
Organism: Mus musculus/domesticus
Length: 250  
Fragment?: false
•
•
•
•
•
Protein
A5CVE1
Organism: Mus musculus/domesticus
Length: 264  
Fragment?: false
•
•
•
•
•
Publication
38823019 | J:352176
First Author: Oliveira TY
Year: 2024
Journal: Cell Rep
Title: Quantitative trait loci mapping provides insights into the genetic regulation of dendritic cell numbers in mouse tissues.
Volume: 43
Issue: 6
Pages: 114296
•
•
•
•
•
Publication
26017146 | J:228589
First Author: Vashisht A
Year: 2015
Journal: Am J Physiol Cell Physiol
Title: STIM and Orai proteins as novel targets for cancer therapy. A Review in the Theme: Cell and Molecular Processes in Cancer Metastasis.
Volume: 309
Issue: 7
Pages: C457-69
•
•
•
•
•
Publication
31015290 | J:280742
 
First Author: Eckstein M
Year: 2019
Journal: Sci Signal
Title: Differential regulation of Ca2+ influx by ORAI channels mediates enamel mineralization.
Volume: 12
Issue: 578
•
•
•
•
•
Publication
32929002 | J:296268
First Author: Grimes D
Year: 2020
Journal: Proc Natl Acad Sci U S A
Title: ORAI1 and ORAI2 modulate murine neutrophil calcium signaling, cellular activation, and host defense.
Volume: 117
Issue: 39
Pages: 24403-24414
•
•
•
•
•
Publication
29628897 | J:275884
 
First Author: López E
Year: 2018
Journal: Front Physiol
Title: Stanniocalcin 2 Regulates Non-capacitative Ca2+ Entry and Aggregation in Mouse Platelets.
Volume: 9
Pages: 266
•
•
•
•
•
Publication
32354146 | J:302991
 
First Author: Segin S
Year: 2020
Journal: Cells
Title: Cardiomyocyte-Specific Deletion of Orai1 Reveals Its Protective Role in Angiotensin-II-Induced Pathological Cardiac Remodeling.
Volume: 9
Issue: 5
•
•
•
•
•
Publication
29604961 | J:278536
 
First Author: Tsvilovskyy V
Year: 2018
Journal: Cell Calcium
Title: Deletion of Orai2 augments endogenous CRAC currents and degranulation in mast cells leading to enhanced anaphylaxis.
Volume: 71
Pages: 24-33
•
•
•
•
•
Publication
21183079 | J:292518
First Author: Huttlin EL
Year: 2010
Journal: Cell
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
Volume: 143
Issue: 7
Pages: 1174-89
•
•
•
•
•




MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

© 2002 - 2017 Department of Genetics, University of Cambridge, Downing Street,
Cambridge CB2 3EH, United Kingdom