Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
hamster, Chinese |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
zebrafish |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
The Origin Recognition Complex (ORC) is a six-subunit ATP-dependent DNA-binding complex encoded in yeast by ORC1-6 []. ORC is a central component for eukaryotic DNA replication, and binds chromatin at replication origins throughout the cell cycle []. ORC directs DNA replication throughout the genome and is required for its initiation [, , ]. ORC bound at replication origins serves as the foundation for assembly of the pre-replicative complex (pre-RC), which includes Cdc6, Tah11 (aka Cdt1), and the Mcm2-7 complex [, , ]. Pre-RC assembly during G1 is required for replication licensing of chromosomes prior to DNA synthesis during S phase [, , ]. Cell cycle-regulated phosphorylation of ORC2, ORC6, Cdc6, and MCM by the cyclin-dependent protein kinase Cdc28 regulates initiation of DNA replication, including blocking reinitiation in G2/M phase [, , , ]. In yeast, ORC also plays a role in the establishment of silencing at the mating-type loci Hidden MAT Left (HML) and Hidden MAT Right (HMR) [, , ]. ORC participates in the assembly of transcriptionally silent chromatin at HML and HMR by recruiting the Sir1 silencing protein to the HML and HMR silencers [, , ]. Both ORC1 and ORC5 bind ATP, although only ORC1 has ATPase activity []. The binding of ATP by ORC1 is required for ORC binding to DNA and is essential for cell viability []. The ATPase activity of ORC1 is involved in formation of the pre-RC [, , ]. ATP binding by ORC5 is crucial for the stability of ORC as a whole. Only the ORC1-5 subunits are required for origin binding; ORC6 is essential for maintenance of pre-RCs once formed []. Interactions within ORC suggest that ORC2-3-6 may form a core complex []. ORC homologues have been found in various eukaryotes, including fission yeast, insects, amphibians, and humans []. This entry represents the largest subunit of the origin recognition complex, subunit 1, which directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; exhibits ATPase activity [, ]. Sir3 is the homologue in Saccharomyces cerevisiae []. |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Zisimopoulou P |
Year: |
1998 |
Journal: |
Mol Gen Genet |
Title: |
Mouse homolog of the yeast origin recognition complex subunit ORC1 and chromosomal localization of the cognate mouse gene Orc1. |
Volume: |
260 |
Issue: |
2-3 |
Pages: |
295-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Natale DA |
Year: |
2000 |
Journal: |
EMBO J |
Title: |
Selective instability of Orc1 protein accounts for the absence of functional origin recognition complexes during the M-G(1) transition in mammals. |
Volume: |
19 |
Issue: |
11 |
Pages: |
2728-38 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
840
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Chesnokov IN |
Year: |
2007 |
Journal: |
Int Rev Cytol |
Title: |
Multiple functions of the origin recognition complex. |
Volume: |
256 |
|
Pages: |
69-109 |
|
•
•
•
•
•
|
Publication |
First Author: |
Matsuda K |
Year: |
2007 |
Journal: |
FEMS Yeast Res |
Title: |
Yeast two-hybrid analysis of the origin recognition complex of Saccharomyces cerevisiae: interaction between subunits and identification of binding proteins. |
Volume: |
7 |
Issue: |
8 |
Pages: |
1263-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell SP |
Year: |
1992 |
Journal: |
Nature |
Title: |
ATP-dependent recognition of eukaryotic origins of DNA replication by a multiprotein complex. |
Volume: |
357 |
Issue: |
6374 |
Pages: |
128-34 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell SP |
Year: |
1995 |
Journal: |
Cell |
Title: |
The multidomain structure of Orc1p reveals similarity to regulators of DNA replication and transcriptional silencing. |
Volume: |
83 |
Issue: |
4 |
Pages: |
563-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Gibson DG |
Year: |
2006 |
Journal: |
Genes Cells |
Title: |
Cell cycle execution point analysis of ORC function and characterization of the checkpoint response to ORC inactivation in Saccharomyces cerevisiae. |
Volume: |
11 |
Issue: |
6 |
Pages: |
557-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rao H |
Year: |
1995 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
The origin recognition complex interacts with a bipartite DNA binding site within yeast replicators. |
Volume: |
92 |
Issue: |
6 |
Pages: |
2224-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rowley A |
Year: |
1995 |
Journal: |
EMBO J |
Title: |
Initiation complex assembly at budding yeast replication origins begins with the recognition of a bipartite sequence by limiting amounts of the initiator, ORC. |
Volume: |
14 |
Issue: |
11 |
Pages: |
2631-41 |
|
•
•
•
•
•
|
Publication |
First Author: |
Speck C |
Year: |
2005 |
Journal: |
Nat Struct Mol Biol |
Title: |
ATPase-dependent cooperative binding of ORC and Cdc6 to origin DNA. |
Volume: |
12 |
Issue: |
11 |
Pages: |
965-71 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kelly TJ |
Year: |
2000 |
Journal: |
Annu Rev Biochem |
Title: |
Regulation of chromosome replication. |
Volume: |
69 |
|
Pages: |
829-80 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell SP |
Year: |
2002 |
Journal: |
Annu Rev Biochem |
Title: |
DNA replication in eukaryotic cells. |
Volume: |
71 |
|
Pages: |
333-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Stillman B |
Year: |
2005 |
Journal: |
FEBS Lett |
Title: |
Origin recognition and the chromosome cycle. |
Volume: |
579 |
Issue: |
4 |
Pages: |
877-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Weinreich M |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Binding of cyclin-dependent kinases to ORC and Cdc6p regulates the chromosome replication cycle. |
Volume: |
98 |
Issue: |
20 |
Pages: |
11211-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Nguyen VQ |
Year: |
2001 |
Journal: |
Nature |
Title: |
Cyclin-dependent kinases prevent DNA re-replication through multiple mechanisms. |
Volume: |
411 |
Issue: |
6841 |
Pages: |
1068-73 |
|
•
•
•
•
•
|
Publication |
First Author: |
Archambault V |
Year: |
2005 |
Journal: |
Mol Cell Biol |
Title: |
Disruption of mechanisms that prevent rereplication triggers a DNA damage response. |
Volume: |
25 |
Issue: |
15 |
Pages: |
6707-21 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klemm RD |
Year: |
1997 |
Journal: |
Cell |
Title: |
Coordinate binding of ATP and origin DNA regulates the ATPase activity of the origin recognition complex. |
Volume: |
88 |
Issue: |
4 |
Pages: |
493-502 |
|
•
•
•
•
•
|
Publication |
First Author: |
Klemm RD |
Year: |
2001 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
ATP bound to the origin recognition complex is important for preRC formation. |
Volume: |
98 |
Issue: |
15 |
Pages: |
8361-7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bowers JL |
Year: |
2004 |
Journal: |
Mol Cell |
Title: |
ATP hydrolysis by ORC catalyzes reiterative Mcm2-7 assembly at a defined origin of replication. |
Volume: |
16 |
Issue: |
6 |
Pages: |
967-78 |
|
•
•
•
•
•
|
Publication |
First Author: |
Randell JC |
Year: |
2006 |
Journal: |
Mol Cell |
Title: |
Sequential ATP hydrolysis by Cdc6 and ORC directs loading of the Mcm2-7 helicase. |
Volume: |
21 |
Issue: |
1 |
Pages: |
29-39 |
|
•
•
•
•
•
|
Publication |
First Author: |
Semple JW |
Year: |
2006 |
Journal: |
EMBO J |
Title: |
An essential role for Orc6 in DNA replication through maintenance of pre-replicative complexes. |
Volume: |
25 |
Issue: |
21 |
Pages: |
5150-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Bell SP |
Year: |
2002 |
Journal: |
Genes Dev |
Title: |
The origin recognition complex: from simple origins to complex functions. |
Volume: |
16 |
Issue: |
6 |
Pages: |
659-72 |
|
•
•
•
•
•
|
Publication |
First Author: |
Triolo T |
Year: |
1996 |
Journal: |
Nature |
Title: |
Role of interactions between the origin recognition complex and SIR1 in transcriptional silencing. |
Volume: |
381 |
Issue: |
6579 |
Pages: |
251-3 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fox CA |
Year: |
1997 |
Journal: |
Science |
Title: |
The origin recognition complex, SIR1, and the S phase requirement for silencing. |
Volume: |
276 |
Issue: |
5318 |
Pages: |
1547-51 |
|
•
•
•
•
•
|
Publication |
First Author: |
Dutta A |
Year: |
1997 |
Journal: |
Annu Rev Cell Dev Biol |
Title: |
Initiation of DNA replication in eukaryotic cells. |
Volume: |
13 |
|
Pages: |
293-332 |
|
•
•
•
•
•
|
Publication |
First Author: |
Varunan SM |
Year: |
2013 |
Journal: |
Mol Biochem Parasitol |
Title: |
Plasmodium falciparum origin recognition complex subunit 1 (PfOrc1) functionally complements Δsir3 mutant of Saccharomyces cerevisiae. |
Volume: |
191 |
Issue: |
1 |
Pages: |
28-35 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
811
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
811
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
805
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
840
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
840
 |
Fragment?: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Jaremko MJ |
Year: |
2020 |
Journal: |
Elife |
Title: |
The dynamic nature of the human origin recognition complex revealed through five cryoEM structures. |
Volume: |
9 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Okano-Uchida T |
Year: |
2018 |
Journal: |
Genes Dev |
Title: |
Endoreduplication of the mouse genome in the absence of ORC1. |
Volume: |
32 |
Issue: |
13-14 |
Pages: |
978-990 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kneissl M |
Year: |
2003 |
Journal: |
J Mol Biol |
Title: |
Interaction and assembly of murine pre-replicative complex proteins in yeast and mouse cells. |
Volume: |
327 |
Issue: |
1 |
Pages: |
111-28 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6388687 |
Age: |
embryonic day 17.5 |
Image: |
6 |
|
Specimen Label: |
E17.5 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388687 |
Age: |
postnatal week 1 |
Image: |
6 |
|
Specimen Label: |
1wk |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388687 |
Age: |
postnatal week 2 |
Image: |
6 |
|
Specimen Label: |
2wk |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388687 |
Age: |
postnatal week 3 |
Image: |
6 |
|
Specimen Label: |
3wk |
Detected: |
false |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388687 |
Age: |
postnatal week 6 |
Image: |
6 |
|
Specimen Label: |
6wk |
Detected: |
false |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388633 |
Assay Type: |
RT-PCR |
Annotation Date: |
2020-02-05 |
Strength: |
Absent |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388687 |
Age: |
postnatal week 9 |
Image: |
6 |
|
Specimen Label: |
9wk |
Detected: |
false |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388625 |
Assay Type: |
Western blot |
Annotation Date: |
2020-02-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684625 |
|
Stage: |
TS25 |
Assay Id: |
MGI:6388696 |
Age: |
embryonic day 17.5 |
Image: |
S5 |
|
Specimen Label: |
E17.5 liver |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:6388625 |
Assay Type: |
Western blot |
Annotation Date: |
2020-02-05 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6388696 |
Age: |
postnatal week 6 |
Image: |
S5 |
|
Specimen Label: |
6wk liver |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6691344 |
Age: |
postnatal adult |
Image: |
JAX_1122931 |
|
Specimen Label: |
JAX_1122931 |
Detected: |
false |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Female |
Emaps: |
EMAPS:1796228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6691344 |
Age: |
postnatal adult |
Image: |
JAX_1122933 |
|
Specimen Label: |
JAX_1122933 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1881228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6691344 |
Age: |
postnatal adult |
Image: |
JAX_1122929 |
|
Specimen Label: |
JAX_1122929 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sundberg JP |
Year: |
2017 |
Journal: |
PLoS One |
Title: |
Systematic screening for skin, hair, and nail abnormalities in a large-scale knockout mouse program. |
Volume: |
12 |
Issue: |
7 |
Pages: |
e0180682 |
|
•
•
•
•
•
|
Publication |
First Author: |
Birgit Meldal and Sandra Orchard (1). (1) European Bioinformatics Institute (EBI), Hinxton, Cambridgeshire, United Kingdom |
Year: |
2023 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to homologous complexes by curator judgment of sequence, composition and function similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ingham NJ |
Year: |
2019 |
Journal: |
PLoS Biol |
Title: |
Mouse screen reveals multiple new genes underlying mouse and human hearing loss. |
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17 |
Issue: |
4 |
Pages: |
e3000194 |
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First Author: |
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2016 |
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Nature |
Title: |
High-throughput discovery of novel developmental phenotypes. |
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537 |
Issue: |
7621 |
Pages: |
508-514 |
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First Author: |
Mouse Genome Informatics Scientific Curators |
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2005 |
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Title: |
Mouse Synonym Curation |
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First Author: |
Hansen J |
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2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
A large-scale, gene-driven mutagenesis approach for the functional analysis of the mouse genome. |
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First Author: |
The Jackson Laboratory |
Year: |
2012 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by The Jackson Laboratory |
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First Author: |
Koscielny G |
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2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
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42 |
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D802-9 |
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First Author: |
Stryke D |
Year: |
2003 |
Journal: |
Nucleic Acids Res |
Title: |
BayGenomics: a resource of insertional mutations in mouse embryonic stem cells. |
Volume: |
31 |
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1999 |
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Database Download |
Title: |
WashU-HHMI Mouse EST Project |
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First Author: |
International Mouse Strain Resource |
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2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
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Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
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First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
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2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
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Hansen GM |
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2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
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18 |
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10 |
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First Author: |
The Gene Ontology Consortium |
Year: |
2014 |
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Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-rat orthologs |
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Publication |
First Author: |
DDB, FB, MGI, GOA, ZFIN curators |
Year: |
2001 |
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Title: |
Gene Ontology annotation through association of InterPro records with GO terms |
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2005 |
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Science |
Title: |
The transcriptional landscape of the mammalian genome. |
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5740 |
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First Author: |
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2024 |
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Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
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MGD Nomenclature Committee |
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1995 |
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Title: |
Nomenclature Committee Use |
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First Author: |
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Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
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100 |
Issue: |
24 |
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14109-14 |
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First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
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474 |
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7351 |
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First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
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