Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim JH |
Year: |
2008 |
Journal: |
J Mol Biol |
Title: |
Upstream stimulatory factors regulate OSCAR gene expression in RANKL-mediated osteoclast differentiation. |
Volume: |
383 |
Issue: |
3 |
Pages: |
502-11 |
|
•
•
•
•
•
|
Publication |
First Author: |
Barrow AD |
Year: |
2011 |
Journal: |
J Clin Invest |
Title: |
OSCAR is a collagen receptor that costimulates osteoclastogenesis in DAP12-deficient humans and mice. |
Volume: |
121 |
Issue: |
9 |
Pages: |
3505-16 |
|
•
•
•
•
•
|
Publication |
First Author: |
Park DR |
Year: |
2020 |
Journal: |
Nat Commun |
Title: |
Osteoclast-associated receptor blockade prevents articular cartilage destruction via chondrocyte apoptosis regulation. |
Volume: |
11 |
Issue: |
1 |
Pages: |
4343 |
|
•
•
•
•
•
|
Publication |
First Author: |
Ishikawa S |
Year: |
2004 |
Journal: |
Int Immunol |
Title: |
Involvement of FcRgamma in signal transduction of osteoclast-associated receptor (OSCAR). |
Volume: |
16 |
Issue: |
7 |
Pages: |
1019-25 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim N |
Year: |
2002 |
Journal: |
J Exp Med |
Title: |
A novel member of the leukocyte receptor complex regulates osteoclast differentiation. |
Volume: |
195 |
Issue: |
2 |
Pages: |
201-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sinningen K |
Year: |
2013 |
Journal: |
Biochem Biophys Res Commun |
Title: |
Monocytic expression of osteoclast-associated receptor (OSCAR) is induced in atherosclerotic mice and regulated by oxidized low-density lipoprotein in vitro. |
Volume: |
437 |
Issue: |
2 |
Pages: |
314-8 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim Y |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Contribution of nuclear factor of activated T cells c1 to the transcriptional control of immunoreceptor osteoclast-associated receptor but not triggering receptor expressed by myeloid cells-2 during osteoclastogenesis. |
Volume: |
280 |
Issue: |
38 |
Pages: |
32905-13 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim K |
Year: |
2005 |
Journal: |
J Biol Chem |
Title: |
Nuclear factor of activated T cells c1 induces osteoclast-associated receptor gene expression during tumor necrosis factor-related activation-induced cytokine-mediated osteoclastogenesis. |
Volume: |
280 |
Issue: |
42 |
Pages: |
35209-16 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Absent |
Sex: |
Male |
Emaps: |
EMAPS:1868128 |
|
Stage: |
TS28 |
Assay Id: |
MGI:6692495 |
Age: |
postnatal adult |
Image: |
BCM_1519762 |
Note: |
vas deferens |
Specimen Label: |
BCM_1519762 |
Detected: |
false |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2021-04-16 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
Pattern: |
Not Specified |
Stage: |
TS28 |
Assay Id: |
MGI:6692495 |
Age: |
postnatal adult |
Image: |
BCM_1519762 |
|
Specimen Label: |
BCM_1519762 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Lee J |
Year: |
2006 |
Journal: |
Blood |
Title: |
Id helix-loop-helix proteins negatively regulate TRANCE-mediated osteoclast differentiation. |
Volume: |
107 |
Issue: |
7 |
Pages: |
2686-93 |
|
•
•
•
•
•
|
Allele |
Name: |
proteasome (prosome, macropain) activator subunit 4; Bench to Bassinet Program (B2B/CVDC), mutation 1508 Cecilia Lo |
Allele Type: |
Chemically induced (ENU) |
|
|
•
•
•
•
•
|
Allele |
Name: |
LPS-responsive beige-like anchor; mutation 1, Bruce Beutler |
Allele Type: |
Chemically induced (ENU) |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Publication |
First Author: |
Ruiz S |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Limiting replication stress during somatic cell reprogramming reduces genomic instability in induced pluripotent stem cells. |
Volume: |
6 |
|
Pages: |
8036 |
|
•
•
•
•
•
|
Publication |
First Author: |
Kim K |
Year: |
2007 |
Journal: |
J Immunol |
Title: |
Protein inhibitor of activated STAT 3 modulates osteoclastogenesis by down-regulation of NFATc1 and osteoclast-associated receptor. |
Volume: |
178 |
Issue: |
9 |
Pages: |
5588-94 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schulze J |
Year: |
2011 |
Journal: |
J Bone Miner Res |
Title: |
Interleukin-33 is expressed in differentiated osteoblasts and blocks osteoclast formation from bone marrow precursor cells. |
Volume: |
26 |
Issue: |
4 |
Pages: |
704-17 |
|
•
•
•
•
•
|
Transgene |
Type: |
transgene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2016 |
|
Title: |
Automatic assignment of GO terms using logical inference, based on on inter-ontology links |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Koscielny G |
Year: |
2014 |
Journal: |
Nucleic Acids Res |
Title: |
The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. |
Volume: |
42 |
Issue: |
Database issue |
Pages: |
D802-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
International Knockout Mouse Consortium |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of modified allele data from IKMC and creation of new knockout alleles |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
International Mouse Strain Resource |
Year: |
2014 |
Journal: |
Database Download |
Title: |
MGI download of germline transmission data for alleles from IMSR strain data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Wellcome Trust Sanger Institute |
Year: |
2009 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
GemPharmatech |
Year: |
2020 |
|
Title: |
GemPharmatech Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Skarnes WC |
Year: |
2011 |
Journal: |
Nature |
Title: |
A conditional knockout resource for the genome-wide study of mouse gene function. |
Volume: |
474 |
Issue: |
7351 |
Pages: |
337-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cyagen Biosciences Inc. |
Year: |
2022 |
|
Title: |
Cyagen Biosciences Website. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
265
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
López-Contreras AJ |
Year: |
2012 |
Journal: |
J Exp Med |
Title: |
An extra allele of Chk1 limits oncogene-induced replicative stress and promotes transformation. |
Volume: |
209 |
Issue: |
3 |
Pages: |
455-61 |
|
•
•
•
•
•
|
Publication |
First Author: |
Marqués-Torrejón MÁ |
Year: |
2013 |
Journal: |
Cell Stem Cell |
Title: |
Cyclin-dependent kinase inhibitor p21 controls adult neural stem cell expansion by regulating Sox2 gene expression. |
Volume: |
12 |
Issue: |
1 |
Pages: |
88-100 |
|
•
•
•
•
•
|
Publication |
First Author: |
Alvarez S |
Year: |
2015 |
Journal: |
Nat Commun |
Title: |
Replication stress caused by low MCM expression limits fetal erythropoiesis and hematopoietic stem cell functionality. |
Volume: |
6 |
|
Pages: |
8548 |
|
•
•
•
•
•
|
Allele |
Name: |
transgene insertion 1, Oscar Fernandez-Capetillo |
Allele Type: |
Transgenic |
Attribute String: |
Inserted expressed sequence |
|
•
•
•
•
•
|
Strain |
Attribute String: |
transgenic, mutant stock |
|
•
•
•
•
•
|
Allele |
Name: |
ataxia telangiectasia and Rad3 related; targeted mutation 1, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
ataxia telangiectasia and Rad3 related; targeted mutation 2, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
ribonucleotide reductase M1; targeted mutation 1.1, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
Attribute String: |
Not Specified |
|
•
•
•
•
•
|
Allele |
Name: |
atypical chemokine receptor 1 (Duffy blood group); targeted mutation 1, Oscar Pogo |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
lin-9 DREAM MuvB core complex component; targeted mutation 1, Oscar R Colamonici |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant stock |
|
•
•
•
•
•
|
Publication |
First Author: |
Lopez-Contreras AJ |
Year: |
2015 |
Journal: |
Genes Dev |
Title: |
Increased Rrm2 gene dosage reduces fragile site breakage and prolongs survival of ATR mutant mice. |
Volume: |
29 |
Issue: |
7 |
Pages: |
690-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Pacheco S |
Year: |
2019 |
Journal: |
Chromosoma |
Title: |
ATR function is indispensable to allow proper mammalian follicle development. |
Volume: |
128 |
Issue: |
3 |
Pages: |
489-500 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
mutant stock, targeted mutation |
|
•
•
•
•
•
|
Allele |
Name: |
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase; targeted mutation 1.1, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
|
|
•
•
•
•
•
|
Allele |
Name: |
NSE2/MMS21 homolog, SMC5-SMC6 complex SUMO ligase; targeted mutation 2.1, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready, No functional change |
|
•
•
•
•
•
|
Allele |
Name: |
polymerase (DNA-directed), delta 3, accessory subunit; targeted mutation 1.2, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
Attribute String: |
Null/knockout |
|
•
•
•
•
•
|
Allele |
Name: |
polymerase (DNA-directed), delta 3, accessory subunit; targeted mutation 1.1, Oscar Fernandez-Capetillo |
Allele Type: |
Targeted |
Attribute String: |
Conditional ready |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atr/Atr |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atr/Atr |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rrm1/Rrm1 |
Background: |
involves: 129 * C57BL/6 * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Atr/Atr |
Background: |
involves: 129 * C57BL/6 |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Luo H |
Year: |
2000 |
Journal: |
Mol Cell Biol |
Title: |
Deletion of the murine Duffy gene (Dfy) reveals that the Duffy receptor is functionally redundant. |
Volume: |
20 |
Issue: |
9 |
Pages: |
3097-101 |
|
•
•
•
•
•
|
Publication |
First Author: |
Edderkaoui B |
Year: |
2018 |
Journal: |
Front Mol Neurosci |
Title: |
Deficiency of Duffy Antigen Receptor for Chemokines Ameliorated Cochlear Damage From Noise Exposure. |
Volume: |
11 |
|
Pages: |
173 |
|
•
•
•
•
•
|
Publication |
First Author: |
Xu L |
Year: |
2007 |
Journal: |
Angiogenesis |
Title: |
Duffy antigen/receptor for chemokines (DARC) attenuates angiogenesis by causing senescence in endothelial cells. |
Volume: |
10 |
Issue: |
4 |
Pages: |
307-18 |
|
•
•
•
•
•
|
Publication |
First Author: |
Rundle CH |
Year: |
2013 |
Journal: |
PLoS One |
Title: |
Duffy antigen receptor for chemokines regulates post-fracture inflammation. |
Volume: |
8 |
Issue: |
10 |
Pages: |
e77362 |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Ackr1/Ackr1 |
Background: |
involves: 129P2/OlaHsd * C57BL/6J |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Lin9/Lin9 |
Background: |
Not Specified |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rrm1/Rrm1 Tg(CAG-Rrm2)#Rsw/? |
Background: |
involves: 129 * C57BL/6 * FVB/N * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Rrm1/Rrm1 Tg(CAG-Rrm2)#Rsw/Tg(CAG-Rrm2)#Rsw |
Background: |
involves: 129 * C57BL/6 * FVB/N * SJL |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Mcm3/Mcm3 Tg(Chek1)1Ofc/? |
Background: |
involves: 129S2/SvPas * C57BL/6 * CD-1 |
Zygosity: |
cx |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Genotype |
Symbol: |
Nsmce2/Nsmce2 |
Background: |
involves: 129 * C57BL/6 * SJL |
Zygosity: |
hm |
Has Mutant Allele: |
true |
|
•
•
•
•
•
|
Publication |
First Author: |
Valdés-Sánchez L |
Year: |
2013 |
Journal: |
Hum Mol Genet |
Title: |
ATR localizes to the photoreceptor connecting cilium and deficiency leads to severe photoreceptor degeneration in mice. |
Volume: |
22 |
Issue: |
8 |
Pages: |
1507-15 |
|
•
•
•
•
•
|