|  Help  |  About  |  Contact Us

Search our database by keyword

Examples

  • Search this entire website. Enter identifiers, names or keywords for genes, diseases, strains, ontology terms, etc. (e.g. Pax6, Parkinson, ataxia)
  • Use OR to search for either of two terms (e.g. OR mus) or quotation marks to search for phrases (e.g. "dna binding").
  • Boolean search syntax is supported: e.g. Balb* for partial matches or mus AND NOT embryo to exclude a term

Search results 1 to 100 out of 132 for Otof

<< First    < Previous  |  Next >    Last >>
0.039s
Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Kazmierczak M
Year: 2017
Journal: J Neurosci
Title: Pejvakin, a Candidate Stereociliary Rootlet Protein, Regulates Hair Cell Function in a Cell-Autonomous Manner.
Volume: 37
Issue: 13
Pages: 3447-3464
Publication
First Author: Stone JS
Year: 2018
Journal: J Assoc Res Otolaryngol
Title: Characterization of Adult Vestibular Organs in 11 CreER Mouse Lines.
Volume: 19
Issue: 4
Pages: 381-399
Publication      
First Author: NIH Neuroscience Blueprint Cre Driver Network
Year: 2009
Journal: MGI Direct Data Submission
Title: Cre recombinase-expressing mice generated for the NIH Neuroscience Blueprint Cre Driver Network
Publication
First Author: Martersteck EM
Year: 2017
Journal: Cell Rep
Title: Diverse Central Projection Patterns of Retinal Ganglion Cells.
Volume: 18
Issue: 8
Pages: 2058-2072
Publication      
First Author: Allen Institute for Brain Science
Year: 2009
Journal: MGI Direct Data Submission
Title: Cre transgenes and knockin alleles created at the Allen Insitute for Brain Science (AIBS)
Publication  
First Author: Harris JA
Year: 2014
Journal: Front Neural Circuits
Title: Anatomical characterization of Cre driver mice for neural circuit mapping and manipulation.
Volume: 8
Pages: 76
Publication
First Author: Yasunaga S
Year: 2000
Journal: Am J Hum Genet
Title: OTOF encodes multiple long and short isoforms: genetic evidence that the long ones underlie recessive deafness DFNB9.
Volume: 67
Issue: 3
Pages: 591-600
Allele
Name: otoferlin; targeted mutation 2.1, Ulrich Mueller
Allele Type: Targeted
Attribute String: Inducible, Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: targeted mutation, mutant strain, congenic
Allele
Name: otoferlin; targeted mutation 1.1, Ulrich Mueller
Allele Type: Targeted
Attribute String: Recombinase
Publication categories: ProxyCollection
Strain
Attribute String: mutant strain, targeted mutation, congenic
Genotype
Symbol: Otof/Otof<+>
Background: involves: C57BL/6 * NZB * SJL
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Otof/Otof<+>
Background: involves: C57BL/6 * NZB * SJL
Zygosity: ht
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Otof/Otof<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Genotype
Symbol: Gt(ROSA)26Sor/Gt(ROSA)26Sor<+> Otof/Otof<+>
Background: involves: 129S6/SvEvTac * C57BL/6
Zygosity: cn
Has Mutant Allele: true
Publication      
First Author: Akil O
Year: 2019
Journal: Proc Natl Acad Sci U S A
Title: Dual AAV-mediated gene therapy restores hearing in a DFNB9 mouse model.
Publication
First Author: Strenzke N
Year: 2016
Journal: EMBO J
Title: Hair cell synaptic dysfunction, auditory fatigue and thermal sensitivity in otoferlin Ile515Thr mutants.
Volume: 35
Issue: 23
Pages: 2519-2535
Publication  
First Author: Chakrabarti R
Year: 2018
Journal: EMBO Rep
Title: Vesicle sub-pool organization at inner hair cell ribbon synapses.
Volume: 19
Issue: 11
Publication
First Author: Tertrais M
Year: 2019
Journal: J Neurosci
Title: Viral Transfer of Mini-Otoferlins Partially Restores the Fast Component of Exocytosis and Uncovers Ultrafast Endocytosis in Auditory Hair Cells of Otoferlin Knock-Out Mice.
Volume: 39
Issue: 18
Pages: 3394-3411
Publication
First Author: Reisinger E
Year: 2011
Journal: J Neurosci
Title: Probing the functional equivalence of otoferlin and synaptotagmin 1 in exocytosis.
Volume: 31
Issue: 13
Pages: 4886-95
Publication
First Author: Longo-Guess C
Year: 2007
Journal: Hear Res
Title: A missense mutation in the conserved C2B domain of otoferlin causes deafness in a new mouse model of DFNB9.
Volume: 234
Issue: 1-2
Pages: 21-8
Publication
First Author: Ramakrishnan NA
Year: 2009
Journal: J Biol Chem
Title: Direct interaction of otoferlin with syntaxin 1A, SNAP-25, and the L-type voltage-gated calcium channel Cav1.3.
Volume: 284
Issue: 3
Pages: 1364-72
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Beurg M
Year: 2008
Journal: J Neurosci
Title: Calcium- and otoferlin-dependent exocytosis by immature outer hair cells.
Volume: 28
Issue: 8
Pages: 1798-803
Publication    
First Author: Michalski N
Year: 2017
Journal: Elife
Title: Otoferlin acts as a Ca2+ sensor for vesicle fusion and vesicle pool replenishment at auditory hair cell ribbon synapses.
Volume: 6
Publication
First Author: Vincent PF
Year: 2014
Journal: J Neurosci
Title: Exocytotic machineries of vestibular type I and cochlear ribbon synapses display similar intrinsic otoferlin-dependent Ca2+ sensitivity but a different coupling to Ca2+ channels.
Volume: 34
Issue: 33
Pages: 10853-69
Publication
First Author: Wright S
Year: 2014
Journal: J Neurophysiol
Title: Synaptic transmission between end bulbs of Held and bushy cells in the cochlear nucleus of mice with a mutation in Otoferlin.
Volume: 112
Issue: 12
Pages: 3173-88
Publication
First Author: Revelo NH
Year: 2014
Journal: J Cell Biol
Title: A new probe for super-resolution imaging of membranes elucidates trafficking pathways.
Volume: 205
Issue: 4
Pages: 591-606
Publication
First Author: Vincent PFY
Year: 2018
Journal: Cell Rep
Title: Clustered Ca2+ Channels Are Blocked by Synaptic Vesicle Proton Release at Mammalian Auditory Ribbon Synapses.
Volume: 25
Issue: 12
Pages: 3451-3464.e3
Publication
First Author: Dulon D
Year: 2009
Journal: J Neurosci
Title: Otoferlin is critical for a highly sensitive and linear calcium-dependent exocytosis at vestibular hair cell ribbon synapses.
Volume: 29
Issue: 34
Pages: 10474-87
Publication
First Author: Pangrsic T
Year: 2010
Journal: Nat Neurosci
Title: Hearing requires otoferlin-dependent efficient replenishment of synaptic vesicles in hair cells.
Volume: 13
Issue: 7
Pages: 869-76
Publication
First Author: Ramakrishnan NA
Year: 2014
Journal: J Biol Chem
Title: Calcium regulates molecular interactions of otoferlin with soluble NSF attachment protein receptor (SNARE) proteins required for hair cell exocytosis.
Volume: 289
Issue: 13
Pages: 8750-66
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_07
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_08
Detected: true
Specimen Num: 4
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_10
Detected: true
Specimen Num: 5
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_11
Detected: true
Specimen Num: 6
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_13
Detected: true
Specimen Num: 7
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_14
Detected: true
Specimen Num: 8
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_15
Detected: true
Specimen Num: 9
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_16
Detected: true
Specimen Num: 10
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_17
Detected: true
Specimen Num: 11
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1756423
Pattern: Single cells
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_18
Detected: true
Specimen Num: 12
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_04
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_05
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_19
Detected: true
Specimen Num: 13
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_20
Detected: true
Specimen Num: 14
GXD Expression  
Probe: MGI:4423741
Assay Type: RNA in situ
Annotation Date: 2010-09-14
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:1856223
Pattern: Regionally restricted
Stage: TS23
Assay Id: MGI:4827002
Age: embryonic day 14.5
Image: euxassay_007676_21
Detected: true
Specimen Num: 15
GXD Expression      
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191003
Age: embryonic day 11.5
Detected: false
Specimen Num: 1
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:6191003
Age: embryonic day 13.5
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689424
Pattern: Not Specified
Stage: TS24
Assay Id: MGI:6191003
Age: embryonic day 15.5
Detected: true
Specimen Num: 3
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689426
Pattern: Not Specified
Stage: TS26
Assay Id: MGI:6191003
Age: embryonic day 18.5
Detected: true
Specimen Num: 4
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 4
Detected: true
Specimen Num: 5
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 14
Detected: true
Specimen Num: 6
GXD Expression    
Probe: MGI:6179909
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191003
Age: postnatal day 28
Detected: true
Specimen Num: 7
Publication
First Author: Noh J
Year: 2010
Journal: Nat Neurosci
Title: Glutamate co-release at GABA/glycinergic synapses is crucial for the refinement of an inhibitory map.
Volume: 13
Issue: 2
Pages: 232-8
Publication
First Author: Johnson SL
Year: 2013
Journal: Proc Natl Acad Sci U S A
Title: Presynaptic maturation in auditory hair cells requires a critical period of sensory-independent spiking activity.
Volume: 110
Issue: 21
Pages: 8720-5
Publication
First Author: Vincent PF
Year: 2017
Journal: J Neurosci
Title: Different CaV1.3 Channel Isoforms Control Distinct Components of the Synaptic Vesicle Cycle in Auditory Inner Hair Cells.
Volume: 37
Issue: 11
Pages: 2960-2975
Publication  
First Author: Eitelmann S
Year: 2020
Journal: Int J Mol Sci
Title: Altered Gap Junction Network Topography in Mouse Models for Human Hereditary Deafness.
Volume: 21
Issue: 19
Publication
First Author: Heidrych P
Year: 2009
Journal: Hum Mol Genet
Title: Otoferlin interacts with myosin VI: implications for maintenance of the basolateral synaptic structure of the inner hair cell.
Volume: 18
Issue: 15
Pages: 2779-90
Publication
First Author: Neef J
Year: 2014
Journal: J Neurosci
Title: Modes and regulation of endocytic membrane retrieval in mouse auditory hair cells.
Volume: 34
Issue: 3
Pages: 705-16
Publication
First Author: Vogl C
Year: 2016
Journal: EMBO J
Title: Tryptophan-rich basic protein (WRB) mediates insertion of the tail-anchored protein otoferlin and is required for hair cell exocytosis and hearing.
Volume: 35
Issue: 23
Pages: 2536-2552
Publication    
First Author: Vincent PF
Year: 2015
Journal: Elife
Title: A synaptic F-actin network controls otoferlin-dependent exocytosis in auditory inner hair cells.
Volume: 4
Publication
First Author: Johnson CP
Year: 2010
Journal: J Cell Biol
Title: Otoferlin is a calcium sensor that directly regulates SNARE-mediated membrane fusion.
Volume: 191
Issue: 1
Pages: 187-97
Protein
Organism: Mus musculus
Length: 1977  
Fragment?: false
Publication
First Author: Roux I
Year: 2006
Journal: Cell
Title: Otoferlin, defective in a human deafness form, is essential for exocytosis at the auditory ribbon synapse.
Volume: 127
Issue: 2
Pages: 277-89
Publication
First Author: Beurg M
Year: 2010
Journal: J Neurosci
Title: Control of exocytosis by synaptotagmins and otoferlin in auditory hair cells.
Volume: 30
Issue: 40
Pages: 13281-90
Publication
First Author: Duncker SV
Year: 2013
Journal: J Neurosci
Title: Otoferlin couples to clathrin-mediated endocytosis in mature cochlear inner hair cells.
Volume: 33
Issue: 22
Pages: 9508-19
Publication
First Author: Wilson L
Year: 2005
Journal: Genome Res
Title: Random mutagenesis of proximal mouse chromosome 5 uncovers predominantly embryonic lethal mutations.
Volume: 15
Issue: 8
Pages: 1095-105
Publication  
First Author: Ching YH
Year: 2010
Journal: BMC Genet
Title: High resolution mapping and positional cloning of ENU-induced mutations in the Rw region of mouse chromosome 5.
Volume: 11
Pages: 106
Publication
First Author: Vogl C
Year: 2015
Journal: J Cell Sci
Title: Unconventional molecular regulation of synaptic vesicle replenishment in cochlear inner hair cells.
Volume: 128
Issue: 4
Pages: 638-44
Publication
First Author: Schwander M
Year: 2007
Journal: J Neurosci
Title: A forward genetics screen in mice identifies recessive deafness traits and reveals that pejvakin is essential for outer hair cell function.
Volume: 27
Issue: 9
Pages: 2163-75
Publication
First Author: Mendus D
Year: 2014
Journal: Eur J Neurosci
Title: Thrombospondins 1 and 2 are important for afferent synapse formation and function in the inner ear.
Volume: 39
Issue: 8
Pages: 1256-67
Publication  
First Author: Wolter S
Year: 2018
Journal: Front Neural Circuits
Title: GC-B Deficient Mice With Axon Bifurcation Loss Exhibit Compromised Auditory Processing.
Volume: 12
Pages: 65
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication
First Author: Thompson CL
Year: 2014
Journal: Neuron
Title: A high-resolution spatiotemporal atlas of gene expression of the developing mouse brain.
Volume: 83
Issue: 2
Pages: 309-323
Publication      
First Author: International Mouse Strain Resource
Year: 2014
Journal: Database Download
Title: MGI download of germline transmission data for alleles from IMSR strain data
Publication      
First Author: Wellcome Trust Sanger Institute
Year: 2009
Journal: MGI Direct Data Submission
Title: Alleles produced for the KOMP project by the Wellcome Trust Sanger Institute
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Rat to Mouse ISO GO annotation transfer
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database