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Search results 1 to 70 out of 70 for Otor

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: dog, domestic
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: frog, western clawed
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: chimpanzee
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Domain
Type: Family
Description: Otoraplin, also known as MIAL (MIA-like), is specifically expressed in the cochlea and the vestibule of the inner ear and may contribute to inner ear dysfunction in humans []. It is a member of the MIA family. MIA (melanoma inhibitory activity) family members include MIA, MIAL, MIA2, and MIA3 (also called TANGO). MIA was found to be strongly expressed and secreted by malignant melanomas. It contains a domain that adopts a Src Homology 3 (SH3) domain-like fold; however, it contains an additional antiparallel beta sheet and two disulfide bonds compared to classical SH3 domains. Unlike classical SH3 domains, MIA does not bind proline-rich ligands [, ].
Publication
First Author: Rendtorff ND
Year: 2001
Journal: Genomics
Title: Identification and characterization of an inner ear-expressed human melanoma inhibitory activity (MIA)-like gene (MIAL) with a frequent polymorphism that abolishes translation.
Volume: 71
Issue: 1
Pages: 40-52
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 128  
Fragment?: false
Publication
First Author: Stoll R
Year: 2008
Journal: Curr Protein Pept Sci
Title: Extracellular SH3 domain containing proteins--features of a new protein family.
Volume: 9
Issue: 3
Pages: 221-6
Publication
First Author: Stoll R
Year: 2003
Journal: Protein Sci
Title: Backbone dynamics of the human MIA protein studied by (15)N NMR relaxation: implications for extended interactions of SH3 domains.
Volume: 12
Issue: 3
Pages: 510-9
Publication
First Author: Robertson NG
Year: 2000
Journal: Genomics
Title: A novel conserved cochlear gene, OTOR: identification, expression analysis, and chromosomal mapping.
Volume: 66
Issue: 3
Pages: 242-8
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression    
Probe: MGI:3510759
Assay Type: RT-PCR
Annotation Date: 2004-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1666917
Stage: TS17
Assay Id: MGI:3510796
Age: embryonic day 10.5
Image: 2
Specimen Label: None
Detected: true
Specimen Num: 1
GXD Expression    
Probe: MGI:3510759
Assay Type: RT-PCR
Annotation Date: 2004-12-13
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1619421
Stage: TS21
Assay Id: MGI:3510796
Age: embryonic day 13.5
Image: 2
Specimen Label: None
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:3797251
Assay Type: RT-PCR
Annotation Date: 2008-07-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672820
Stage: TS20
Assay Id: MGI:3797257
Age: embryonic day 12.5
Specimen Label: Not shown
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:6111888
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111913
Age: embryonic day 18.5
Specimen Label: +/+
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:6111888
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111913
Age: embryonic day 18.5
Specimen Label: +/-
Detected: true
Specimen Num: 2
GXD Expression      
Probe: MGI:6111888
Assay Type: RT-PCR
Annotation Date: 2018-01-25
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1603926
Stage: TS26
Assay Id: MGI:6111913
Age: embryonic day 18.5
Specimen Label: -/-
Detected: true
Specimen Num: 3
GXD Expression  
Probe: MGI:3510888
Assay Type: RNA in situ
Annotation Date: 2004-12-14
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1759621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3510889
Age: embryonic day 13.5
Note: Transcript is weak/absent.
Specimen Label: Table 1
Detected: true
Specimen Num: 1
Publication
First Author: Cohen-Salmon M
Year: 2000
Journal: J Biol Chem
Title: Fdp, a new fibrocyte-derived protein related to MIA/CD-RAP, has an in vitro effect on the early differentiation of the inner ear mesenchyme.
Volume: 275
Issue: 51
Pages: 40036-41
Publication
First Author: Lin S
Year: 2008
Journal: Dev Biol
Title: Misexpression of MIA disrupts lung morphogenesis and causes neonatal death.
Volume: 316
Issue: 2
Pages: 441-55
Publication
First Author: Moser M
Year: 2002
Journal: Mol Cell Biol
Title: Ultrastructural cartilage abnormalities in MIA/CD-RAP-deficient mice.
Volume: 22
Issue: 5
Pages: 1438-45
Publication
First Author: Monks DC
Year: 2012
Journal: Dev Dyn
Title: Identification of putative retinoic acid target genes downstream of mesenchymal Tbx1 during inner ear development.
Volume: 241
Issue: 3
Pages: 563-73
Publication
First Author: Ficker M
Year: 2004
Journal: Dev Biol
Title: Analysis of genes from inner ear developmental-stage cDNA subtraction reveals molecular regionalization of the otic capsule.
Volume: 268
Issue: 1
Pages: 7-23
Publication
First Author: Bohnenpoll T
Year: 2014
Journal: Dev Biol
Title: Canonical Wnt signaling regulates the proliferative expansion and differentiation of fibrocytes in the murine inner ear.
Volume: 391
Issue: 1
Pages: 54-65
Publication
First Author: Desai J
Year: 2006
Journal: Hum Mol Genet
Title: Nell1-deficient mice have reduced expression of extracellular matrix proteins causing cranial and vertebral defects.
Volume: 15
Issue: 8
Pages: 1329-41
Publication      
First Author: Shanghai Model Organisms Center
Year: 2017
Journal: MGI Direct Data Submission
Title: Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China
Publication
First Author: Tang T
Year: 2010
Journal: Nat Biotechnol
Title: A mouse knockout library for secreted and transmembrane proteins.
Volume: 28
Issue: 7
Pages: 749-55
Publication      
First Author: Lexicon Genetics, Inc
Year: 2011
Journal: Database Download
Title: MGI download of Lexicon knockout data
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication      
First Author: The Jackson Laboratory Mouse Radiation Hybrid Database
Year: 2004
Journal: Database Release
Title: Mouse T31 Radiation Hybrid Data Load
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2).
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Allele
Name: otoraplin; endonuclease-mediated mutation 1, Shanghai Model Organisms Center
Allele Type: Endonuclease-mediated
Attribute String: Null/knockout
Publication
First Author: Bosserhoff AK
Year: 2004
Journal: Gene Expr Patterns
Title: Characterization and expression pattern of the novel MIA homolog TANGO.
Volume: 4
Issue: 4
Pages: 473-9