Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Protein Domain |
Type: |
Family |
Description: |
Otulin (also known as FAM105B) belongs to the ovarian tumour (OTU) deubiquitinases (DUBs) family []. It specifically removes linear ('Met-1'-linked) polyubiquitin chains to substrates and acts as a regulator of angiogenesis and innate immune response []. It associates with the LUBAC complex via direct interaction with RNF31 and counteracts its action by cleaving linear polyubiquitin chains to substrates []. |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Publication |
First Author: |
Rivkin E |
Year: |
2013 |
Journal: |
Nature |
Title: |
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis. |
Volume: |
498 |
Issue: |
7454 |
Pages: |
318-24 |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
58
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
352
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Keusekotten K |
Year: |
2013 |
Journal: |
Cell |
Title: |
OTULIN antagonizes LUBAC signaling by specifically hydrolyzing Met1-linked polyubiquitin. |
Volume: |
153 |
Issue: |
6 |
Pages: |
1312-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Damgaard RB |
Year: |
2016 |
Journal: |
Cell |
Title: |
The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity. |
Volume: |
166 |
Issue: |
5 |
Pages: |
1215-1230.e20 |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Heger K |
Year: |
2018 |
Journal: |
Nature |
Title: |
OTULIN limits cell death and inflammation by deubiquitinating LUBAC. |
Volume: |
559 |
Issue: |
7712 |
Pages: |
120-124 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mevissen TE |
Year: |
2013 |
Journal: |
Cell |
Title: |
OTU deubiquitinases reveal mechanisms of linkage specificity and enable ubiquitin chain restriction analysis. |
Volume: |
154 |
Issue: |
1 |
Pages: |
169-84 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verboom L |
Year: |
2023 |
Journal: |
Cell Death Dis |
Title: |
OTULIN protects the intestinal epithelium from apoptosis during inflammation and infection. |
Volume: |
14 |
Issue: |
8 |
Pages: |
534 |
|
•
•
•
•
•
|
Publication |
First Author: |
Damgaard RB |
Year: |
2020 |
Journal: |
Cell Death Differ |
Title: |
OTULIN protects the liver against cell death, inflammation, fibrosis, and cancer. |
Volume: |
27 |
Issue: |
5 |
Pages: |
1457-1474 |
|
•
•
•
•
•
|
Publication |
First Author: |
Schünke H |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
OTULIN inhibits RIPK1-mediated keratinocyte necroptosis to prevent skin inflammation in mice. |
Volume: |
12 |
Issue: |
1 |
Pages: |
5912 |
|
•
•
•
•
•
|
Publication |
First Author: |
Hoste E |
Year: |
2021 |
Journal: |
Nat Commun |
Title: |
OTULIN maintains skin homeostasis by controlling keratinocyte death and stem cell identity. |
Volume: |
12 |
Issue: |
1 |
Pages: |
5913 |
|
•
•
•
•
•
|
Publication |
First Author: |
Fu Y |
Year: |
2021 |
Journal: |
Mol Cell |
Title: |
OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin. |
Volume: |
81 |
Issue: |
15 |
Pages: |
3187-3204.e7 |
|
•
•
•
•
•
|
Publication |
First Author: |
Doglio MG |
Year: |
2023 |
Journal: |
Sci Immunol |
Title: |
Myeloid OTULIN deficiency couples RIPK3-dependent cell death to Nlrp3 inflammasome activation and IL-1β secretion. |
Volume: |
8 |
Issue: |
89 |
Pages: |
eadf4404 |
|
•
•
•
•
•
|
Publication |
First Author: |
Verboom L |
Year: |
2020 |
Journal: |
Cell Rep |
Title: |
OTULIN Prevents Liver Inflammation and Hepatocellular Carcinoma by Inhibiting FADD- and RIPK1 Kinase-Mediated Hepatocyte Apoptosis. |
Volume: |
30 |
Issue: |
7 |
Pages: |
2237-2247.e6 |
|
•
•
•
•
•
|
Publication |
First Author: |
Almeida SM |
Year: |
2023 |
Journal: |
Dis Model Mech |
Title: |
An interaction between OTULIN and SCRIB uncovers roles for linear ubiquitination in planar cell polarity. |
Volume: |
16 |
Issue: |
8 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
van Wijk SJL |
Year: |
2017 |
Journal: |
Nat Microbiol |
Title: |
Linear ubiquitination of cytosolic Salmonella Typhimurium activates NF-κB and restricts bacterial proliferation. |
Volume: |
2 |
|
Pages: |
17066 |
|
•
•
•
•
•
|
Publication |
First Author: |
Takiuchi T |
Year: |
2014 |
Journal: |
Genes Cells |
Title: |
Suppression of LUBAC-mediated linear ubiquitination by a specific interaction between LUBAC and the deubiquitinases CYLD and OTULIN. |
Volume: |
19 |
Issue: |
3 |
Pages: |
254-72 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615402 |
Assay Type: |
Northern blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603914 |
|
Stage: |
TS14 |
Assay Id: |
MGI:5615403 |
Age: |
embryonic day 9.0 |
|
|
Specimen Label: |
E9.0 |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615402 |
Assay Type: |
Northern blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
|
Stage: |
TS17 |
Assay Id: |
MGI:5615403 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
E10.5 |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615402 |
Assay Type: |
Northern blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603922 |
|
Stage: |
TS22 |
Assay Id: |
MGI:5615403 |
Age: |
embryonic day 14.5 |
|
|
Specimen Label: |
E14.5 |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Western blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5615404 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Western blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5615404 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Gum/Gum |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Western blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5615405 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
+/+ |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Western blot |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603920 |
|
Stage: |
TS20 |
Assay Id: |
MGI:5615405 |
Age: |
embryonic day 12.5 |
|
|
Specimen Label: |
Gum/Gum |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1689428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Brain |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1672828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Lung |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Heart |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3598828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Skeletal muscle |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3276028 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Bone marrow |
Detected: |
true |
Specimen Num: |
5 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876828 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Thymus |
Detected: |
true |
Specimen Num: |
6 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876728 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Spleen |
Detected: |
true |
Specimen Num: |
7 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1684628 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Liver |
Detected: |
true |
Specimen Num: |
8 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1737328 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Kidney |
Detected: |
true |
Specimen Num: |
9 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1702128 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Stomach |
Detected: |
true |
Specimen Num: |
10 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3283428 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Small intestine |
Detected: |
true |
Specimen Num: |
11 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1893928 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Colon |
Detected: |
true |
Specimen Num: |
12 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Male |
Emaps: |
EMAPS:1797228 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Testis |
Detected: |
true |
Specimen Num: |
13 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5911522 |
Assay Type: |
Western blot |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752528 |
|
Stage: |
TS28 |
Assay Id: |
MGI:5911524 |
Age: |
postnatal adult |
|
|
Specimen Label: |
Skin |
Detected: |
true |
Specimen Num: |
14 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611816 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.0 |
|
|
Specimen Label: |
S5b |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611819 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 11.5 |
|
Note: |
Expression was detected in distal branchial arches. |
Specimen Label: |
S5c,f |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1752321 |
Pattern: |
Not Specified |
Stage: |
TS21 |
Assay Id: |
MGI:5911519 |
Age: |
embryonic day 13.5 |
|
|
Specimen Label: |
S2C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610516 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.0 |
|
|
Specimen Label: |
S5b |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1610519 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
S5c,f |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603917 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in neural crest cells. |
Specimen Label: |
2j,k,l |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603916 |
Pattern: |
Regionally restricted |
Stage: |
TS16 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.0 |
|
Note: |
Expression was detected in neural crest cells. |
Specimen Label: |
S5b |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1603919 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 11.5 |
|
Note: |
Expression was detected in neural crest. |
Specimen Label: |
S5c,f |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2j,k,l |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5615256 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in a subset of endothelial cells, often located near possible leading regions of vessels. |
Specimen Label: |
2m,n |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5615256 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in endothelial cells. |
Specimen Label: |
2o |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615258 |
Assay Type: |
Immunohistochemistry |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274317 |
Pattern: |
Regionally restricted |
Stage: |
TS17 |
Assay Id: |
MGI:5615256 |
Age: |
embryonic day 10.5 |
|
Note: |
Expression was detected in a subset of endothelial cells, often located near possible leading regions of vessels. |
Specimen Label: |
2p |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:3274315 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 9.5 |
|
Note: |
Expression was in intersomitic vessels. |
Specimen Label: |
S5a,d,e |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627216 |
Pattern: |
Not Specified |
Stage: |
TS16 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.0 |
|
|
Specimen Label: |
S5b |
Detected: |
true |
Specimen Num: |
3 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1627219 |
Pattern: |
Regionally restricted |
Stage: |
TS19 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 11.5 |
|
Note: |
Expression was detected in distal branchial arches. |
Specimen Label: |
S5c,f |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1620415 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
S5a,d,e |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
|
Assay Type: |
In situ reporter (knock in) |
Annotation Date: |
2017-10-17 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1876521 |
Pattern: |
Regionally restricted |
Stage: |
TS21 |
Assay Id: |
MGI:5911519 |
Age: |
embryonic day 13.5 |
|
Note: |
Expression is in the spleen. |
Specimen Label: |
S2C |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634615 |
Pattern: |
Not Specified |
Stage: |
TS15 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 9.5 |
|
|
Specimen Label: |
S5a,d,e |
Detected: |
true |
Specimen Num: |
2 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1634619 |
Pattern: |
Not Specified |
Stage: |
TS19 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 11.5 |
|
|
Specimen Label: |
S5c,f |
Detected: |
true |
Specimen Num: |
4 |
|
•
•
•
•
•
|
GXD Expression |
Probe: |
MGI:5615248 |
Assay Type: |
RNA in situ |
Annotation Date: |
2015-02-11 |
Strength: |
Present |
Sex: |
Not Specified |
Emaps: |
EMAPS:1611717 |
Pattern: |
Not Specified |
Stage: |
TS17 |
Assay Id: |
MGI:5615250 |
Age: |
embryonic day 10.5 |
|
|
Specimen Label: |
2j,k,l |
Detected: |
true |
Specimen Num: |
1 |
|
•
•
•
•
•
|
Publication |
First Author: |
Esapa C |
Year: |
2010 |
Journal: |
Unpublished |
Title: |
Information obtained from the Mammalian Genetics Unit, Medical Research Council (MRC), Harwell, UK. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mar L |
Year: |
2005 |
Journal: |
J Neurosci |
Title: |
A genetic screen for mutations that affect cranial nerve development in the mouse. |
Volume: |
25 |
Issue: |
50 |
Pages: |
11787-95 |
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The RIKEN BioResource Center |
Year: |
2006 |
Journal: |
Unpublished |
Title: |
Information obtained from The RIKEN BioResource Center |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
MGC Data curation in Mouse Genome Informatics |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGI and IMPC |
Year: |
2018 |
Journal: |
Database Release |
Title: |
MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC) |
Year: |
2014 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|