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Search results 1 to 100 out of 493 for P2rx7

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Type Details Score
Gene
5027 | P2RX7
Type: gene
Organism: human
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Gene
286814 | P2RX7
Type: gene
Organism: cattle
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Gene
771952 | P2RX7
Type: gene
Organism: chicken
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Gene
387298 | p2rx7
Type: gene
Organism: zebrafish
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Gene
699455 | P2RX7
Type: gene
Organism: macaque, rhesus
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Gene
100490662 | p2rx7
Type: gene
Organism: frog, western clawed
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Gene
29665 | P2rx7
Type: gene
Organism: rat
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Gene
448778 | P2RX7
Type: gene
Organism: dog, domestic
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Gene
452318 | P2RX7
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1339957 | P2rx7
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
33510147 | J:301006
First Author: Douguet L
Year: 2021
Journal: Nat Commun
Title: A small-molecule P2RX7 activator promotes anti-tumor immune responses and sensitizes lung tumor to immunotherapy.
Volume: 12
Issue: 1
Pages: 653
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Publication
37967010 | J:343502
First Author: Santiago-Carvalho I
Year: 2023
Journal: Cell Rep
Title: T cell-specific P2RX7 favors lung parenchymal CD4(+) T cell accumulation in response to severe lung infections.
Volume: 42
Issue: 11
Pages: 113448
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Publication
25998681 | J:321318
First Author: Wang H
Year: 2015
Journal: Cell Res
Title: P2RX7 sensitizes Mac-1/ICAM-1-dependent leukocyte-endothelial adhesion and promotes neurovascular injury during septic encephalopathy.
Volume: 25
Issue: 6
Pages: 674-90
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Publication
27858314 | J:244726
First Author: Metzger MW
Year: 2017
Journal: Purinergic Signal
Title: Genetically dissecting P2rx7 expression within the central nervous system using conditional humanized mice.
Volume: 13
Issue: 2
Pages: 153-170
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Publication
21983632 | J:180087
First Author: Notomi S
Year: 2011
Journal: Am J Pathol
Title: Critical involvement of extracellular ATP acting on P2RX7 purinergic receptors in photoreceptor cell death.
Volume: 179
Issue: 6
Pages: 2798-809
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Publication
23308196 | J:195812
First Author: Notomi S
Year: 2013
Journal: PLoS One
Title: Dynamic increase in extracellular ATP accelerates photoreceptor cell apoptosis via ligation of P2RX7 in subretinal hemorrhage.
Volume: 8
Issue: 1
Pages: e53338
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Publication
25948251 | J:221649
First Author: Hu SJ
Year: 2015
Journal: J Neurosci
Title: Upregulation of P2RX7 in Cx3cr1-Deficient Mononuclear Phagocytes Leads to Increased Interleukin-1β Secretion and Photoreceptor Neurodegeneration.
Volume: 35
Issue: 18
Pages: 6987-96
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Publication
30949163 | J:281787
 
First Author: Felix KM
Year: 2019
Journal: Front Immunol
Title: P2RX7 Deletion in T Cells Promotes Autoimmune Arthritis by Unleashing the Tfh Cell Response.
Volume: 10
Pages: 411
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Publication
36993971 | J:337583
 
First Author: de Salles ÉM
Year: 2023
Journal: Front Immunol
Title: P2RX7 signaling drives the differentiation of Th1 cells through metabolic reprogramming for aerobic glycolysis.
Volume: 14
Pages: 1140426
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Publication
29973721 | J:266276
First Author: Borges da Silva H
Year: 2018
Journal: Nature
Title: The purinergic receptor P2RX7 directs metabolic fitness of long-lived memory CD8+ T cells.
Volume: 559
Issue: 7713
Pages: 264-268
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Publication
29858571 | J:266313
First Author: Yang R
Year: 2018
Journal: Nat Commun
Title: Tet1 and Tet2 maintain mesenchymal stem cell homeostasis via demethylation of the P2rX7 promoter.
Volume: 9
Issue: 1
Pages: 2143
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Publication
26461208 | J:328095
First Author: Sinadinos A
Year: 2015
Journal: PLoS Med
Title: P2RX7 purinoceptor: a therapeutic target for ameliorating the symptoms of duchenne muscular dystrophy.
Volume: 12
Issue: 10
Pages: e1001888
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GXD Expression
GXD Expression
     
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689419
Stage: TS19
Assay Id: MGI:6191010
Age: embryonic day 11.5
Specimen Label: Table S2 - E11.5 - P2rx7
Detected: false
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:6191010
Age: embryonic day 13.5
Specimen Label: Table S2 - E13.5 - P2rx7
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689424
Stage: TS24
Assay Id: MGI:6191010
Age: embryonic day 15.5
Specimen Label: Table S2 - E15.5 - P2rx7
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Absent
Sex: Male
Emaps: EMAPS:1689426
Stage: TS26
Assay Id: MGI:6191010
Age: embryonic day 18.5
Specimen Label: Table S2 - E18.5 - P2rx7
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
   
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191010
Age: postnatal day 4
Specimen Label: Table S2 - P4 - P2rx7
Detected: true
Specimen Num: 5
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GXD Expression
GXD Expression
   
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191010
Age: postnatal day 14
Specimen Label: Table S2 - P14 - P2rx7
Detected: true
Specimen Num: 6
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GXD Expression
GXD Expression
   
Probe: MGI:6179962
Assay Type: RNA in situ
Annotation Date: 2018-07-25
Strength: Present
Sex: Male
Emaps: EMAPS:1689428
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:6191010
Age: postnatal day 28
Specimen Label: Table S2 - P28 - P2rx7
Detected: true
Specimen Num: 7
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Publication
32640257 | J:305048
First Author: Borges da Silva H
Year: 2020
Journal: Immunity
Title: Sensing of ATP via the Purinergic Receptor P2RX7 Promotes CD8+ Trm Cell Generation by Enhancing Their Sensitivity to the Cytokine TGF-β.
Volume: 53
Issue: 1
Pages: 158-171.e6
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Publication
25564520 | J:218901
First Author: Hofman P
Year: 2015
Journal: Cancer Res
Title: Genetic and pharmacological inactivation of the purinergic P2RX7 receptor dampens inflammation but increases tumor incidence in a mouse model of colitis-associated cancer.
Volume: 75
Issue: 5
Pages: 835-45
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Publication
33336163 | J:305294
First Author: Er-Lukowiak M
Year: 2020
Journal: iScience
Title: A P2rx7 Passenger Mutation Affects the Vitality and Function of T cells in Congenic Mice.
Volume: 23
Issue: 12
Pages: 101870
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Publication
33563723 | J:303762
First Author: Prades S
Year: 2021
Journal: J Neurosci
Title: Functional P2X7 Receptors in the Auditory Nerve of Hearing Rodents Localize Exclusively to Peripheral Glia.
Volume: 41
Issue: 12
Pages: 2615-2629
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Publication
23139414 | J:250416
First Author: García-Huerta P
Year: 2012
Journal: J Biol Chem
Title: The specificity protein factor Sp1 mediates transcriptional regulation of P2X7 receptors in the nervous system.
Volume: 287
Issue: 53
Pages: 44628-44
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Publication
26631939 | J:293013
 
First Author: Jimenez-Mateos EM
Year: 2015
Journal: Sci Rep
Title: microRNA targeting of the P2X7 purinoceptor opposes a contralateral epileptogenic focus in the hippocampus.
Volume: 5
Pages: 17486
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Publication
33199725 | J:299022
First Author: Ramírez-Fernández A
Year: 2020
Journal: Sci Rep
Title: Deviant reporter expression and P2X4 passenger gene overexpression in the soluble EGFP BAC transgenic P2X7 reporter mouse model.
Volume: 10
Issue: 1
Pages: 19876
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Publication
35163829 | J:325891
 
First Author: Zhao YF
Year: 2022
Journal: Int J Mol Sci
Title: High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus.
Volume: 23
Issue: 3
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Publication
35935830 | J:327603
 
First Author: Zhang Y
Year: 2022
Journal: Front Pharmacol
Title: ATP indirectly stimulates hippocampal CA1 and CA3 pyramidal neurons via the activation of neighboring P2X7 receptor-bearing astrocytes and NG2 glial cells, respectively.
Volume: 13
Pages: 944541
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Publication
25740510 | J:219936
First Author: Hirayama Y
Year: 2015
Journal: J Neurosci
Title: Astrocyte-mediated ischemic tolerance.
Volume: 35
Issue: 9
Pages: 3794-805
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Publication
22198387 | J:325858
First Author: Engel T
Year: 2012
Journal: FASEB J
Title: Seizure suppression and neuroprotection by targeting the purinergic P2X7 receptor during status epilepticus in mice.
Volume: 26
Issue: 4
Pages: 1616-28
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Publication
27466191 | J:238574
First Author: Sebastián-Serrano Á
Year: 2016
Journal: Hum Mol Genet
Title: Neurodevelopmental alterations and seizures developed by mouse model of infantile hypophosphatasia are associated with purinergic signalling deregulation.
Volume: 25
Issue: 19
Pages: 4143-4156
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Publication
29079688 | J:251657
First Author: Metzger MW
Year: 2017
Journal: J Neurosci
Title: Heterozygosity for the Mood Disorder-Associated Variant Gln460Arg Alters P2X7 Receptor Function and Sleep Quality.
Volume: 37
Issue: 48
Pages: 11688-11700
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Publication
19546214 | J:165960
First Author: Nicke A
Year: 2009
Journal: J Biol Chem
Title: A functional P2X7 splice variant with an alternative transmembrane domain 1 escapes gene inactivation in P2X7 knock-out mice.
Volume: 284
Issue: 38
Pages: 25813-22
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Publication
32699136 | J:296322
First Author: Romagnani A
Year: 2020
Journal: Cancer Res
Title: P2X7 Receptor Activity Limits Accumulation of T Cells within Tumors.
Volume: 80
Issue: 18
Pages: 3906-3919
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Publication
30777922 | J:272967
First Author: Borges da Silva H
Year: 2019
Journal: J Immunol
Title: ARTC2.2/P2RX7 Signaling during Cell Isolation Distorts Function and Quantification of Tissue-Resident CD8+ T Cell and Invariant NKT Subsets.
Volume: 202
Issue: 7
Pages: 2153-2163
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Publication
36098250 | J:337838
First Author: Baroja-Mazo A
Year: 2023
Journal: Br J Pharmacol
Title: P2X7 receptor activation impairs antitumour activity of natural killer cells.
Volume: 180
Issue: 1
Pages: 111-128
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Publication
22447075 | J:183554
First Author: Sorge RE
Year: 2012
Journal: Nat Med
Title: Genetically determined P2X7 receptor pore formation regulates variability in chronic pain sensitivity.
Volume: 18
Issue: 4
Pages: 595-9
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Publication
30552101 | J:321678
 
First Author: Stark R
Year: 2018
Journal: Sci Immunol
Title: T RM maintenance is regulated by tissue damage via P2RX7.
Volume: 3
Issue: 30
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Publication
22243662 | J:232387
First Author: Csölle C
Year: 2013
Journal: Int J Neuropsychopharmacol
Title: The absence of P2X7 receptors (P2rx7) on non-haematopoietic cells leads to selective alteration in mood-related behaviour with dysregulated gene expression and stress reactivity in mice.
Volume: 16
Issue: 1
Pages: 213-33
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Publication
30653952 | J:277199
First Author: Moreira-Souza ACA
Year: 2019
Journal: Am J Pathol
Title: Disruption of Purinergic Receptor P2X7 Signaling Increases Susceptibility to Cerebral Toxoplasmosis.
Volume: 189
Issue: 4
Pages: 730-738
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Publication
29018292 | J:255681
First Author: Arguin G
Year: 2017
Journal: Sci Rep
Title: The loss of P2X7 receptor expression leads to increase intestinal glucose transit and hepatic steatosis.
Volume: 7
Issue: 1
Pages: 12917
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Publication
23089744 | J:193771
First Author: Deplano S
Year: 2013
Journal: J Leukoc Biol
Title: P2X7 receptor-mediated Nlrp3-inflammasome activation is a genetic determinant of macrophage-dependent crescentic glomerulonephritis.
Volume: 93
Issue: 1
Pages: 127-34
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Publication
31693933 | J:285079
 
First Author: Smith KL
Year: 2020
Journal: Neurosci Lett
Title: P2X7 receptor knockout mice display less aggressive biting behaviour correlating with increased brain activation in the piriform cortex.
Volume: 714
Pages: 134575
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Publication
28597172 | J:257112
First Author: Geraghty NJ
Year: 2017
Journal: Purinergic Signal
Title: The P2X7 receptor is not essential for development of imiquimod-induced psoriasis-like inflammation in mice.
Volume: 13
Issue: 4
Pages: 405-415
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Publication
27824163 | J:299023
 
First Author: Koványi B
Year: 2016
Journal: Sci Rep
Title: The role of P2X7 receptors in a rodent PCP-induced schizophrenia model.
Volume: 6
Pages: 36680
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Publication
19767732 | J:154302
First Author: Ghiringhelli F
Year: 2009
Journal: Nat Med
Title: Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
Volume: 15
Issue: 10
Pages: 1170-8
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Publication
30626694 | J:273018
First Author: Philips RL
Year: 2019
Journal: J Immunol
Title: Cutting Edge: HDAC3 Protects Double-Positive Thymocytes from P2X7 Receptor-Induced Cell Death.
Volume: 202
Issue: 4
Pages: 1033-1038
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Publication
30683682 | J:273863
First Author: Horváth G
Year: 2019
Journal: J Neurosci
Title: P2X7 Receptors Drive Poly(I:C) Induced Autism-like Behavior in Mice.
Volume: 39
Issue: 13
Pages: 2542-2561
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Publication
23805233 | J:204206
First Author: Csölle C
Year: 2013
Journal: PLoS One
Title: Neurochemical Changes in the Mouse Hippocampus Underlying the Antidepressant Effect of Genetic Deletion of P2X7 Receptors.
Volume: 8
Issue: 6
Pages: e66547
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Publication
29075178 | J:268974
 
First Author: Gölöncsér F
Year: 2017
Journal: Front Mol Neurosci
Title: Regulation of Hippocampal 5-HT Release by P2X7 Receptors in Response to Optogenetic Stimulation of Median Raphe Terminals of Mice.
Volume: 10
Pages: 325
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Publication
34516970 | J:334154
 
First Author: Di Lauro C
Year: 2022
Journal: Prog Neurobiol
Title: P2X7 receptor blockade reduces tau induced toxicity, therapeutic implications in tauopathies.
Volume: 208
Pages: 102173
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Publication
37101546 | J:335774
 
First Author: von Mücke-Heim IA
Year: 2023
Journal: Front Pharmacol
Title: The human P2X7 receptor alters microglial morphology and cytokine secretion following immunomodulation.
Volume: 14
Pages: 1148190
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Publication
21357538 | J:169661
First Author: Chen YG
Year: 2011
Journal: J Immunol
Title: Testing the role of P2X7 receptors in the development of type 1 diabetes in nonobese diabetic mice.
Volume: 186
Issue: 7
Pages: 4278-84
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Publication
27666820 | J:279179
First Author: Gao Q
Year: 2016
Journal: Mol Med Rep
Title: Long non-coding RNAs regulate effects of β-crystallin B2 on mouse ovary development.
Volume: 14
Issue: 5
Pages: 4223-4231
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Publication
28495929 | J:268946
First Author: Rothmeier AS
Year: 2017
Journal: Arterioscler Thromb Vasc Biol
Title: Tissue Factor Prothrombotic Activity Is Regulated by Integrin-arf6 Trafficking.
Volume: 37
Issue: 7
Pages: 1323-1331
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Publication
30952430 | J:300636
First Author: Arkhipov SN
Year: 2019
Journal: Biochem Biophys Res Commun
Title: ATP release into ADPKD cysts via pannexin-1/P2X7 channels decreases ENaC activity.
Volume: 513
Issue: 1
Pages: 166-171
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Publication
19066285 | J:146064
First Author: Armstrong S
Year: 2009
Journal: J Cell Sci
Title: Activation of P2X7 receptors causes isoform-specific translocation of protein kinase C in osteoclasts.
Volume: 122
Issue: Pt 1
Pages: 136-44
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Protein Coding Gene
MGP_CAROLIEiJ_G0027710 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0030055 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0030020 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029956 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0030031 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0029748 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1339957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0030484 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0029157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0029718 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0029868 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0029824 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029957 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0029855 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0030525 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0028871 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0029232 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0024290 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0028708 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
9849870 | J:51040
First Author: Chessell IP
Year: 1998
Journal: FEBS Lett
Title: Cloning and functional characterisation of the mouse P2X7 receptor.
Volume: 439
Issue: 1-2
Pages: 26-30
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Publication
30065030 | J:265165
First Author: Tezza S
Year: 2018
Journal: Diabetes
Title: Islet-Derived eATP Fuels Autoreactive CD8+ T Cells and Facilitates the Onset of Type 1 Diabetes.
Volume: 67
Issue: 10
Pages: 2038-2053
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Publication
38164435 | J:344270
 
First Author: Falco MV
Year: 2023
Journal: Front Cell Neurosci
Title: P2X7 receptor activation awakes a dormant stem cell niche in the adult spinal cord.
Volume: 17
Pages: 1288676
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Publication
19171786 | J:150552
First Author: Díaz-Hernández M
Year: 2009
Journal: FASEB J
Title: Altered P2X7-receptor level and function in mouse models of Huntington's disease and therapeutic efficacy of antagonist administration.
Volume: 23
Issue: 6
Pages: 1893-906
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Publication
37287063 | J:337840
First Author: Bianchi C
Year: 2023
Journal: Alzheimers Res Ther
Title: P2X7 receptor inhibition ameliorates ubiquitin-proteasome system dysfunction associated with Alzheimer's disease.
Volume: 15
Issue: 1
Pages: 105
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Publication
29222907 | J:272650
     
First Author: Xia M
Year: 2017
Journal: J Neurochem
Title: The ameliorative effect of fluoxetine on neuroinflammation induced by sleep deprivation.
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Publication
20739479 | J:181824
First Author: Oliveira JF
Year: 2011
Journal: Cereb Cortex
Title: Rodent cortical astroglia express in situ functional P2X7 receptors sensing pathologically high ATP concentrations.
Volume: 21
Issue: 4
Pages: 806-20
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Publication
28848393 | J:313127
 
First Author: Albalawi F
Year: 2017
Journal: Front Cell Neurosci
Title: The P2X7 Receptor Primes IL-1β and the NLRP3 Inflammasome in Astrocytes Exposed to Mechanical Strain.
Volume: 11
Pages: 227
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Publication
32982684 | J:299014
 
First Author: Conte G
Year: 2020
Journal: Front Mol Neurosci
Title: P2X7 Receptor-Dependent microRNA Expression Profile in the Brain Following Status Epilepticus in Mice.
Volume: 13
Pages: 127
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Publication
34572093 | J:313602
 
First Author: Conte G
Year: 2021
Journal: Cells
Title: Circulating P2X7 Receptor Signaling Components as Diagnostic Biomarkers for Temporal Lobe Epilepsy.
Volume: 10
Issue: 9
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Publication
36634819 | J:334147
     
First Author: Jooss T
Year: 2023
Journal: Mucosal Immunol
Title: Macrophages and glia are the dominant P2X7-expressing cell types in the gut nervous system-No evidence for the role of neuronal P2X7 receptors in colitis.
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Publication
36507708 | J:337858
First Author: Morgan J
Year: 2023
Journal: Epilepsia
Title: Increased uptake of the P2X7 receptor radiotracer (18) F-JNJ-64413739 in the brain and peripheral organs according to the severity of status epilepticus in male mice.
Volume: 64
Issue: 2
Pages: 511-523
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Publication
12370338 | J:79540
First Author: Adriouch S
Year: 2002
Journal: J Immunol
Title: Cutting edge: a natural P451L mutation in the cytoplasmic domain impairs the function of the mouse P2X7 receptor.
Volume: 169
Issue: 8
Pages: 4108-12
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Publication
34950860 | J:317970
First Author: Barrera-Avalos C
Year: 2021
Journal: iScience
Title: P2X7 receptor is essential for cross-dressing of bone marrow-derived dendritic cells.
Volume: 24
Issue: 12
Pages: 103520
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