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Search results 1 to 100 out of 104 for Pabpc5

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Type Details Score
Gene
Type: gene
Organism: human
Gene
Type: gene
Organism: chimpanzee
Gene
Type: gene
Organism: cattle
Gene
Type: gene
Organism: macaque, rhesus
Gene
Type: gene
Organism: gorilla, western
Gene
Type: gene
Organism: orangutan, Bornean
Gene
Type: gene
Organism: hamster, Chinese
Gene
Type: gene
Organism: rat
Gene
Type: gene
Organism: dog, domestic
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Gene
Type: gene
Organism: human
Publication
First Author: Blanco P
Year: 2001
Journal: Genomics
Title: A novel poly(A)-binding protein gene (PABPC5) maps to an X-specific subinterval in the Xq21.3/Yp11.2 homology block of the human sex chromosomes.
Volume: 74
Issue: 1
Pages: 1-11
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: mouse, laboratory
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
GXD Expression      
Probe: MGI:3614462
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616217
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: false
Specimen Num: 1
GXD Expression      
Probe: MGI:3614462
Assay Type: RT-PCR
Annotation Date: 2006-03-15
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616217
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: false
Specimen Num: 2
GXD Expression      
Probe: MGI:3615038
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689421
Stage: TS21
Assay Id: MGI:3616660
Age: embryonic day 13.5
Specimen Label: RT-PCR E13.5 brain
Detected: true
Specimen Num: 1
GXD Expression      
Probe: MGI:3615038
Assay Type: RT-PCR
Annotation Date: 2006-03-16
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689427
Stage: TS27
Assay Id: MGI:3616660
Age: postnatal day 0
Specimen Label: RT-PCR P0 brain
Detected: true
Specimen Num: 2
GXD Expression    
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1665821
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1691627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1760621
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: true
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1760627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1697427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression    
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1716821
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Specimen Label: E13.5
Detected: false
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1716827
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753627
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1754421
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression in precortical tissue.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754427
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3284527
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1679727
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754027
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: true
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3280927
Pattern: Not Specified
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: P0
Specimen Num: 2
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:3267921
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression  
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Ambiguous
Sex: Not Specified
Emaps: EMAPS:1757721
Pattern: Not Specified
Stage: TS21
Assay Id: MGI:3617174
Age: embryonic day 13.5
Image: E13.5
Note: Authors indicate that there was either ubiquitous or background expression.
Specimen Label: E13.5
Specimen Num: 1
GXD Expression    
Probe: MGI:3615806
Assay Type: RNA in situ
Annotation Date: 2006-03-21
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1757727
Stage: TS27
Assay Id: MGI:3617174
Age: postnatal day 0
Image: P0
Specimen Label: P0
Detected: false
Specimen Num: 2
Publication  
First Author: McKee AE
Year: 2005
Journal: BMC Dev Biol
Title: A genome-wide in situ hybridization map of RNA-binding proteins reveals anatomically restricted expression in the developing mouse brain.
Volume: 5
Pages: 14
Publication      
First Author: MGI and IMPC
Year: 2018
Journal: Database Release
Title: MGI Load of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Function or Process or Component Unknown following Literature Review
Publication      
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Chromosome assignment of mouse genes using the Mouse Genome Sequencing Consortium (MGSC) assembly and the ENSEMBL Database
Publication
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
Publication        
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
Publication      
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
Publication        
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
Publication      
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
Publication      
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
Publication      
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform
Publication      
First Author: Mouse Genome Informatics Group
Year: 2003
Journal: Database Procedure
Title: Automatic Encodes (AutoE) Reference
Publication      
First Author: Mouse Genome Informatics Scientific Curators
Year: 2009
Journal: Database Download
Title: Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform
Publication
First Author: Kazak L
Year: 2013
Journal: Nucleic Acids Res
Title: Alternative translation initiation augments the human mitochondrial proteome.
Volume: 41
Issue: 4
Pages: 2354-69
Publication
First Author: Féral C
Year: 2001
Journal: Nucleic Acids Res
Title: Human testis expresses a specific poly(A)-binding protein.
Volume: 29
Issue: 9
Pages: 1872-83
Publication
First Author: Mangus DA
Year: 2003
Journal: Genome Biol
Title: Poly(A)-binding proteins: multifunctional scaffolds for the post-transcriptional control of gene expression.
Volume: 4
Issue: 7
Pages: 223
Publication
First Author: Deo RC
Year: 1999
Journal: Cell
Title: Recognition of polyadenylate RNA by the poly(A)-binding protein.
Volume: 98
Issue: 6
Pages: 835-45
Publication
First Author: Sladic RT
Year: 2004
Journal: Eur J Biochem
Title: Human PABP binds AU-rich RNA via RNA-binding domains 3 and 4.
Volume: 271
Issue: 2
Pages: 450-7
Publication
First Author: Kini HK
Year: 2016
Journal: RNA
Title: Cytoplasmic poly(A) binding protein-1 binds to genomically encoded sequences within mammalian mRNAs.
Volume: 22
Issue: 1
Pages: 61-74
Publication
First Author: Burgess HM
Year: 2011
Journal: J Cell Sci
Title: Nuclear relocalisation of cytoplasmic poly(A)-binding proteins PABP1 and PABP4 in response to UV irradiation reveals mRNA-dependent export of metazoan PABPs.
Volume: 124
Issue: Pt 19
Pages: 3344-55
Publication
First Author: Kessler SH
Year: 1998
Journal: Mol Cell Biol
Title: RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with eukaryotic translation initiation factor 4G.
Volume: 18
Issue: 1
Pages: 51-7
Protein Domain
Type: Domain
Description: This entry represents the RNA recognition motif 2 (RRM2) of type I poly(A)-binding proteins (PABPs).Poly(A)-binding proteins (PABPs) are highly conserved proteins that bind to the poly(A) tail present at the 3' ends of most eukaryotic mRNAs []. These highly conserved proteins are found only in eukaryotes; single-celled eukaryotes each have a single PABP, whereas humans have five and Arabidopis has eight. In humans, three lineages of PABP proteins are observed: cytoplasmic PABPs (PABPC1, PABPC3, and iPABP); nuclear PABP (PABPN1); and X-linked PABP (PABPC5) []. The mammalian PABPs contain four RNA recognition motifs (RRMs). RRM 1 and 2 are primarily responsible for the high-affinity binding to homopolymeric adenosines, while RRMs 3 and 4 can bind to nonhomopolymeric AU sequences []. Proteins containing this motif include:Polyadenylate-binding protein 1 (PABP-1 or PABPC1): PABP-1 is the major cytoplasmic PABP isoform in adult mouse somatic cells. It is able to bindsimultaneously to the cap-binding complex subunit eIF4G and to the poly(A) tail. Therefore, it has been suggested to play a role in altering the structure and/or function of the translation termination complex. It may have additional functions within the eukaryotic mRNA transcriptome. PABP-1 possesses an A-rich sequence in its 5'-UTR and allows binding of PABP and blockage of translation of its own mRNA []. Polyadenylate-binding protein 3 (PABP-3 or PABPC3): PABP-3 is a testis-specific poly(A)-binding protein specifically expressed in round spermatids. It is mainly found in mammalian and may play an important role in the testis-specific regulation of mRNA homeostasis. PABP-3 shows significant sequence similarity to PABP-1. However, it binds to poly(A) with a lower affinity than PABP-1. Dislike PABP-1, PABP-3 lacks the A-rich sequence in its 5'-UTR []. Polyadenylate-binding protein 4 (PABP-4 or APP-1 or iPABP): PABP-4 is an inducible poly(A)-binding protein (iPABP) that is primarily localized to the cytoplasm. It shows significant sequence similarity to PABP-1 as well. The RNA binding properties of PABP-1 and PABP-4 appear to be identical []. Polyadenylate-binding protein 5 (PABP-5 or PABPC5):PABP-5 is encoded by PABPC5 gene within the X-specific subinterval, and expressed in fetal brain and in a range of adult tissues in mammals, such as ovary and testis. It may play an important role in germ cell development []. Moreover, unlike other PABPs, PABP-5 contains only four RRMs, but lacks both the linker region and the CTD. Polyadenylate-binding protein 1-like (PABP-1-like or PABPC1L): orthologue of PABP-1.Polyadenylate-binding protein 1-like 2 (PABPC1L2 or RBM32): orthologue of PABP-1. Polyadenylate-binding protein 4-like (PABP-4-like or PABPC4L): orthologue of PABP-5. Polyadenylate-binding protein, cytoplasmic and nuclear (PABP or ACBP-67): PABP is a conserved poly(A) binding protein containing poly(A) tails that can be attached to the 3'-ends of mRNAs. The yeast PABP, also known as Pab1, and its homologues may play important roles in the initiation of translation and in mRNA decay []. Like vertebrate PABP-1, Pab1 contains four RRMs, a linker region, and a proline-rich CTD as well. The first two RRMs are mainly responsible for specific binding to poly(A). The proline-rich region may be involved in protein-protein interactions. The association of RRM2 of yeast Pab1 with eIF4G is a prerequisite for the poly(A) tail to stimulate the translation of mRNA in vitro []. Polyadenylate-binding protein Pes4 and Mip6.
Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 172  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 168  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 119  
Fragment?: true
Publication
First Author: Anderson JT
Year: 1993
Journal: Mol Cell Biol
Title: PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae.
Volume: 13
Issue: 10
Pages: 6102-13
Protein
Organism: Mus musculus/domesticus
Length: 266  
Fragment?: true
Protein
Organism: Mus musculus/domesticus
Length: 381  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 370  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 607  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 615  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 631  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 590  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 644  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 603  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 636  
Fragment?: false
Protein
Organism: Mus musculus/domesticus
Length: 660  
Fragment?: false