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Search results 1 to 100 out of 118 for Pak5

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Hits by Pathway

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Hits by Strain

Type Details Score
Gene
57144 | PAK5
Type: gene
Organism: human
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Gene
100145129 | pak5
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR028754 | PAK5
Type: Family
Description: Serine/threonine-protein kinase PAK 5 (PAK5, also known as PAK7) belongs to the mammalian p21-activated kinase (PAK) family of serine/threonine kinases that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival []. PAK5 (PAK7) induces filopodia formation and neurite outgrowth in neuroblastoma cells, perhaps through the Cdc42/Rac pathway []. It is an inhibitor of the MARK2 kinase, which leads to stable microtubules and dynamic actin []. It also has functions in apoptosis [], MAP Kinase pathway []and cancer malignant progression [].
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Gene
311450 | Pak5
Type: gene
Organism: rat
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Gene
485772 | PAK5
Type: gene
Organism: dog, domestic
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Gene
469876 | PAK5
Type: gene
Organism: chimpanzee
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Gene
513432 | PAK5
Type: gene
Organism: cattle
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Gene
416734 | PAK5
Type: gene
Organism: chicken
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Gene
405898 | pak5
Type: gene
Organism: zebrafish
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Gene
719458 | PAK5
Type: gene
Organism: macaque, rhesus
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Protein Coding Gene
MGI:1920334 | Pak5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12897128 | J:84802
First Author: Cotteret S
Year: 2003
Journal: Mol Cell Biol
Title: p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
Volume: 23
Issue: 16
Pages: 5526-39
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Publication
16014608 | -
First Author: Matenia D
Year: 2005
Journal: Mol Biol Cell
Title: PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.
Volume: 16
Issue: 9
Pages: 4410-22
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Publication
11756552 | -
First Author: Dan C
Year: 2002
Journal: Mol Cell Biol
Title: PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells.
Volume: 22
Issue: 2
Pages: 567-77
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Publication
19415746 | -
First Author: Gong W
Year: 2009
Journal: Int J Cancer
Title: P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration.
Volume: 125
Issue: 3
Pages: 548-55
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Publication
18465753 | -
First Author: Wu X
Year: 2008
Journal: J Cell Biochem
Title: p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.
Volume: 105
Issue: 1
Pages: 167-75
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Publication
22371566 | J:182241
First Author: Strochlic TI
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.
Volume: 109
Issue: 11
Pages: 4116-21
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Publication
14517284 | J:85956
First Author: Li X
Year: 2003
Journal: Mol Cell Biol
Title: Targeted disruption of the gene for the PAK5 kinase in mice.
Volume: 23
Issue: 20
Pages: 7134-42
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Protein
Q4KL59
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Publication
18675265 | J:141962
First Author: Nekrasova T
Year: 2008
Journal: Dev Biol
Title: Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion.
Volume: 322
Issue: 1
Pages: 95-108
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Protein
Q8BVB0
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
Q8C015
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Publication
23593460 | J:200575
First Author: Furnari MA
Year: 2013
Journal: PLoS One
Title: Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice.
Volume: 8
Issue: 4
Pages: e61321
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Protein Coding Gene
MGP_CAROLIEiJ_G0024355 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026374 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025811 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025800 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025275 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22732262 | J:190762
First Author: Coste O
Year: 2012
Journal: Behav Brain Res
Title: The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors.
Volume: 234
Issue: 1
Pages: 121-8
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Brain +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Brain -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Kidney +/+
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Kidney -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Lung +/+
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Lung -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Spleen +/+
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Spleen -/-
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:7705565
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705981
Age: postnatal day 7
Image: S3
Specimen Label: cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7705565
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1753628
Stage: TS28
Assay Id: MGI:7705981
Age: postnatal day 7
Image: S3
Specimen Label: thalamus/hypothalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7705565
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754028
Stage: TS28
Assay Id: MGI:7705981
Age: postnatal day 7
Image: S3
Specimen Label: thalamus/hypothalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:7705565
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1754428
Stage: TS28
Assay Id: MGI:7705984
Age: postnatal day 14
Image: S3
Specimen Label: cortex
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:7705565
Assay Type: RT-PCR
Annotation Date: 2024-08-02
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3529528
Stage: TS28
Assay Id: MGI:7705984
Age: postnatal day 14
Image: S3
Specimen Label: (d) thalamus
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:7779996
Assay Type: Western blot
Annotation Date: 2024-11-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1857728
Stage: TS28
Assay Id: MGI:7780018
Age: postnatal day 7
Image: 1
Specimen Label: (lane 1)
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:7779996
Assay Type: Western blot
Annotation Date: 2024-11-15
Strength: Not Specified
Sex: Not Specified
Emaps: EMAPS:1857728
Stage: TS28
Assay Id: MGI:7780018
Age: postnatal day 7
Image: 1
Specimen Label: (lane 2)
Specimen Num: 2
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Graded
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Note: Expression is higher in the superficial layers.
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons but not in surrounding glial cells.
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Cerebral cortex Antisense
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Hippocampus Antisense
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Olfactory bulb Antisense
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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Publication
24474471 | J:210679
First Author: Morris DW
Year: 2014
Journal: Hum Mol Genet
Title: An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.
Volume: 23
Issue: 12
Pages: 3316-26
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Publication
18509032 | J:136389
First Author: Sapir T
Year: 2008
Journal: J Neurosci
Title: Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration.
Volume: 28
Issue: 22
Pages: 5710-20
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Publication
38079473 | J:357470
First Author: Hu B
Year: 2024
Journal: Brain
Title: PAK2 is necessary for myelination in the peripheral nervous system.
Volume: 147
Issue: 5
Pages: 1809-1821
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Publication
19139271 | J:145866
First Author: Gobert RP
Year: 2009
Journal: Mol Cell Biol
Title: Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Volume: 29
Issue: 6
Pages: 1538-53
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Publication
30578296 | J:275368
First Author: Shu P
Year: 2019
Journal: J Biol Chem
Title: The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system.
Volume: 294
Issue: 10
Pages: 3444-3453
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:72245
       
First Author: GOA curators, MGI curators
Year: 2001
Title: Gene Ontology annotation based on Enzyme Commission mapping
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
- | J:346132
       
First Author: The Gene Ontology Consortium
Year: 2016
Title: Automatic assignment of GO terms using logical inference, based on on inter-ontology links
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