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Search results 1 to 100 out of 106 for Pak5

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Hits by Category

Type Details Score
Gene
57144 | PAK5
Type: gene
Organism: human
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Gene
513432 | PAK5
Type: gene
Organism: cattle
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Gene
416734 | PAK5
Type: gene
Organism: chicken
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Gene
405898 | pak5
Type: gene
Organism: zebrafish
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Gene
719458 | PAK5
Type: gene
Organism: macaque, rhesus
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Gene
100145129 | pak5
Type: gene
Organism: frog, western clawed
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Protein Domain
IPR028754 | PAK5
Type: Family
Description: Serine/threonine-protein kinase PAK 5 (PAK5, also known as PAK7) belongs to the mammalian p21-activated kinase (PAK) family of serine/threonine kinases that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival []. PAK5 (PAK7) induces filopodia formation and neurite outgrowth in neuroblastoma cells, perhaps through the Cdc42/Rac pathway []. It is an inhibitor of the MARK2 kinase, which leads to stable microtubules and dynamic actin []. It also has functions in apoptosis [], MAP Kinase pathway []and cancer malignant progression [].
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Gene
311450 | Pak5
Type: gene
Organism: rat
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Gene
485772 | PAK5
Type: gene
Organism: dog, domestic
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Gene
469876 | PAK5
Type: gene
Organism: chimpanzee
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Protein Coding Gene
MGI:1920334 | Pak5
Type: protein_coding_gene
Organism: mouse, laboratory
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Publication
12897128 | J:84802
First Author: Cotteret S
Year: 2003
Journal: Mol Cell Biol
Title: p21-Activated kinase 5 (Pak5) localizes to mitochondria and inhibits apoptosis by phosphorylating BAD.
Volume: 23
Issue: 16
Pages: 5526-39
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Publication
16014608 | -
First Author: Matenia D
Year: 2005
Journal: Mol Biol Cell
Title: PAK5 kinase is an inhibitor of MARK/Par-1, which leads to stable microtubules and dynamic actin.
Volume: 16
Issue: 9
Pages: 4410-22
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Publication
11756552 | -
First Author: Dan C
Year: 2002
Journal: Mol Cell Biol
Title: PAK5, a new brain-specific kinase, promotes neurite outgrowth in N1E-115 cells.
Volume: 22
Issue: 2
Pages: 567-77
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Publication
19415746 | -
First Author: Gong W
Year: 2009
Journal: Int J Cancer
Title: P21-activated kinase 5 is overexpressed during colorectal cancer progression and regulates colorectal carcinoma cell adhesion and migration.
Volume: 125
Issue: 3
Pages: 548-55
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Publication
18465753 | -
First Author: Wu X
Year: 2008
Journal: J Cell Biochem
Title: p21 activated kinase 5 activates Raf-1 and targets it to mitochondria.
Volume: 105
Issue: 1
Pages: 167-75
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Publication
22371566 | J:182241
First Author: Strochlic TI
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: Identification of neuronal substrates implicates Pak5 in synaptic vesicle trafficking.
Volume: 109
Issue: 11
Pages: 4116-21
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Publication
14517284 | J:85956
First Author: Li X
Year: 2003
Journal: Mol Cell Biol
Title: Targeted disruption of the gene for the PAK5 kinase in mice.
Volume: 23
Issue: 20
Pages: 7134-42
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Protein
Q4KL59
Organism: Mus musculus/domesticus
Length: 338  
Fragment?: false
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Publication
18675265 | J:141962
First Author: Nekrasova T
Year: 2008
Journal: Dev Biol
Title: Targeted disruption of the Pak5 and Pak6 genes in mice leads to deficits in learning and locomotion.
Volume: 322
Issue: 1
Pages: 95-108
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Protein
Q8BVB0
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Protein
Q8C015
Organism: Mus musculus/domesticus
Length: 719  
Fragment?: false
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Publication
23593460 | J:200575
First Author: Furnari MA
Year: 2013
Journal: PLoS One
Title: Functional deficits in PAK5, PAK6 and PAK5/PAK6 knockout mice.
Volume: 8
Issue: 4
Pages: e61321
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Protein Coding Gene
MGP_CAROLIEiJ_G0024355 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0026557 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0026521 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0026495 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0026533 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0026276 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_1920334 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0026978 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0025737 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0026256 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0026390 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0026354 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0026494 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0026374 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0027033 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0025473 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0025811 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0025800 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0025275 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
22732262 | J:190762
First Author: Coste O
Year: 2012
Journal: Behav Brain Res
Title: The p21-activated kinase PAK 5 is involved in formalin-induced nociception through regulation of MAP-kinase signaling and formalin-specific receptors.
Volume: 234
Issue: 1
Pages: 121-8
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Brain +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Brain -/-
Detected: false
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Kidney +/+
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1737328
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Kidney -/-
Detected: false
Specimen Num: 4
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Lung +/+
Detected: false
Specimen Num: 5
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1672828
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Lung -/-
Detected: false
Specimen Num: 6
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Spleen +/+
Detected: false
Specimen Num: 7
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1876728
Stage: TS28
Assay Id: MGI:3843165
Age: postnatal week 8
Specimen Label: Spleen -/-
Detected: false
Specimen Num: 8
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: +/+
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Present
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: +/-
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
     
Probe: MGI:3843156
Assay Type: Western blot
Annotation Date: 2009-05-06
Strength: Absent
Sex: Not Specified
Emaps: EMAPS:1689428
Stage: TS28
Assay Id: MGI:3843166
Age: postnatal week 8
Specimen Label: -/-
Detected: false
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:3270422
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Strong
Sex: Not Specified
Emaps: EMAPS:3271122
Pattern: Graded
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Note: Expression is higher in the superficial layers.
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:4424823
Assay Type: RNA in situ
Annotation Date: 2023-10-17
Strength: Present
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7540666
Age: embryonic day 14.5
Specimen Label: Supplementary table 2
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Moderate
Sex: Not Specified
Emaps: EMAPS:3271222
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:1778728
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons but not in surrounding glial cells.
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:1754428
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Cerebral cortex Antisense
Detected: true
Specimen Num: 4
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3284528
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Hippocampus Antisense
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
   
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3522328
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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GXD Expression
GXD Expression
 
Probe: MGI:7545198
Assay Type: RNA in situ
Annotation Date: 2023-11-02
Strength: Weak
Sex: Not Specified
Emaps: EMAPS:1754722
Pattern: Not Specified
Stage: TS22
Assay Id: MGI:7545221
Age: embryonic day 14.0
Image: 1C
Specimen Label: 1C
Detected: true
Specimen Num: 1
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GXD Expression
GXD Expression
 
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3280928
Pattern: Regionally restricted
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Note: Expression was detected in neurons.
Specimen Label: 2B Olfactory bulb Antisense
Detected: true
Specimen Num: 3
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GXD Expression
GXD Expression
   
Probe: MGI:3843153
Assay Type: RNA in situ
Annotation Date: 2009-05-06
Strength: Present
Sex: Female
Emaps: EMAPS:3521728
Pattern: Not Specified
Stage: TS28
Assay Id: MGI:3843164
Age: postnatal week 8
Specimen Label: 2B Cerebellum Antisense
Detected: true
Specimen Num: 2
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Publication
24474471 | J:210679
First Author: Morris DW
Year: 2014
Journal: Hum Mol Genet
Title: An inherited duplication at the gene p21 Protein-Activated Kinase 7 (PAK7) is a risk factor for psychosis.
Volume: 23
Issue: 12
Pages: 3316-26
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Publication
18509032 | J:136389
First Author: Sapir T
Year: 2008
Journal: J Neurosci
Title: Accurate balance of the polarity kinase MARK2/Par-1 is required for proper cortical neuronal migration.
Volume: 28
Issue: 22
Pages: 5710-20
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Publication
19139271 | J:145866
First Author: Gobert RP
Year: 2009
Journal: Mol Cell Biol
Title: Convergent functional genomics of oligodendrocyte differentiation identifies multiple autoinhibitory signaling circuits.
Volume: 29
Issue: 6
Pages: 1538-53
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Publication
30578296 | J:275368
First Author: Shu P
Year: 2019
Journal: J Biol Chem
Title: The spatiotemporal expression pattern of microRNAs in the developing mouse nervous system.
Volume: 294
Issue: 10
Pages: 3444-3453
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Publication
- | J:165964
     
First Author: Mammalian Functional Genomics Centre
Year: 2010
Journal: MGI Direct Data Submission
Title: Alleles produced for the NorCOMM project by the Mammalian Functional Genomics Centre (Mfgc), University of Manitoba
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Publication
18614015 | J:151002
First Author: Pagliarini DJ
Year: 2008
Journal: Cell
Title: A mitochondrial protein compendium elucidates complex I disease biology.
Volume: 134
Issue: 1
Pages: 112-23
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Publication
- | J:237616
     
First Author: MGI and IMPC
Year: 2017
Journal: MGI Direct Data Submission
Title: MGI Curation of Endonuclease-Mediated Alleles (CRISPR) from the International Mouse Phenotyping Consortium (IMPC)
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Publication
- | J:342608
       
First Author: GO Central curators, GOA curators, Rhea curators
Year: 2020
Title: Automatic Gene Ontology annotation based on Rhea mapping
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Publication
- | J:80001
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: FANTOM2 Data Curation in Mouse Genome Informatics
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Publication
34321999 | J:313619
 
First Author: Bedogni F
Year: 2021
Journal: Front Mol Neurosci
Title: Cell-Type-Specific Gene Expression in Developing Mouse Neocortex: Intermediate Progenitors Implicated in Axon Development.
Volume: 14
Pages: 686034
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Publication
- | J:326541
       
First Author: Cyagen Biosciences Inc.
Year: 2022
Title: Cyagen Biosciences Website.
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Publication
- | J:72247
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2001
Title: Gene Ontology Annotation by the MGI Curatorial Staff
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Publication
- | J:211773
     
First Author: Mouse Genome Informatics and the International Mouse Phenotyping Consortium (IMPC)
Year: 2014
Journal: Database Release
Title: Obtaining and Loading Phenotype Annotations from the International Mouse Phenotyping Consortium (IMPC) Database
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Publication
- | J:342605
       
First Author: GOA curators
Year: 2016
Title: Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara
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Publication
16141072 | J:99680
First Author: Carninci P
Year: 2005
Journal: Science
Title: The transcriptional landscape of the mammalian genome.
Volume: 309
Issue: 5740
Pages: 1559-63
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Publication
11217851 | J:65060
First Author: Kawai J
Year: 2001
Journal: Nature
Title: Functional annotation of a full-length mouse cDNA collection.
Volume: 409
Issue: 6821
Pages: 685-90
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Publication
- | J:23000
       
First Author: MGD Nomenclature Committee
Year: 1995
Title: Nomenclature Committee Use
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Publication
- | J:141210
     
First Author: Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI)
Year: 2008
Journal: Database Download
Title: Mouse Gene Trap Data Load from dbGSS
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Publication
- | J:293217
       
First Author: GemPharmatech
Year: 2020
Title: GemPharmatech Website.
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Publication
- | J:60000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2000
Title: Gene Ontology Annotation by electronic association of SwissProt Keywords with GO terms
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Publication
12466851 | J:80000
First Author: Okazaki Y
Year: 2002
Journal: Nature
Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.
Volume: 420
Issue: 6915
Pages: 563-73
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Publication
- | J:164563
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2010
Title: Human to Mouse ISO GO annotation transfer
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Publication
21267068 | J:153498
First Author: Diez-Roux G
Year: 2011
Journal: PLoS Biol
Title: A high-resolution anatomical atlas of the transcriptome in the mouse embryo.
Volume: 9
Issue: 1
Pages: e1000582
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Publication
- | J:57747
     
First Author: MGI Genome Annotation Group and UniGene Staff
Year: 2015
Journal: Database Download
Title: MGI-UniGene Interconnection Effort
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Publication
- | J:75000
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2002
Title: Mouse Genome Informatics Computational Sequence to Gene Associations
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Publication
- | J:161428
       
First Author: Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas
Year: 2010
Title: Annotation inferences using phylogenetic trees
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Publication
- | J:53168
     
First Author: Bairoch A
Year: 1999
Journal: Database Release
Title: SWISS-PROT Annotated protein sequence database
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Publication
- | J:91388
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations
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Publication
- | J:90438
       
First Author: Mouse Genome Informatics Scientific Curators
Year: 2005
Title: Obtaining and loading genome assembly coordinates from NCBI annotations
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Publication
- | J:155721
     
First Author: Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI)
Year: 2010
Journal: Database Download
Title: Consensus CDS project
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Publication
- | J:155221
     
First Author: Mouse Genome Informatics
Year: 2010
Journal: Database Release
Title: Protein Ontology Association Load.
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Publication
- | J:63103
     
First Author: Mouse Genome Database and National Center for Biotechnology Information
Year: 2000
Journal: Database Release
Title: Entrez Gene Load
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Publication
- | J:262123
     
First Author: Allen Institute for Brain Science
Year: 2004
Journal: Allen Institute
Title: Allen Brain Atlas: mouse riboprobes
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

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