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Search results 1 to 100 out of 285 for Park7

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Hits by Pathway

Hits by Strain

Hits by Category

Type Details Score
Gene
11315 | PARK7
Type: gene
Organism: human
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Gene
746063 | PARK7
Type: gene
Organism: chimpanzee
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Gene
479595 | PARK7
Type: gene
Organism: dog, domestic
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Gene
511268 | PARK7
Type: gene
Organism: cattle
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Gene
395277 | PARK7
Type: gene
Organism: chicken
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Gene
449674 | park7
Type: gene
Organism: zebrafish
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Gene
708377 | PARK7
Type: gene
Organism: macaque, rhesus
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Gene
548568 | park7
Type: gene
Organism: frog, western clawed
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Gene
117287 | Park7
Type: gene
Organism: rat
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Protein Coding Gene
MGI:2135637 | Park7
Type: protein_coding_gene
Organism: mouse, laboratory
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Gene
100422232 | PARK7P2
Type: gene
Organism: human
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Gene
100422296 | PARK7P1
Type: gene
Organism: human
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Publication
24637782 | J:215105
First Author: Yu H
Year: 2014
Journal: PLoS One
Title: Park7 expression influences myotube size and myosin expression in muscle.
Volume: 9
Issue: 3
Pages: e92030
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Publication
34093596 | J:314528
 
First Author: Yin L
Year: 2021
Journal: Front Immunol
Title: PARK7 Protects Against Chronic Kidney Injury and Renal Fibrosis by Inducing SOD2 to Reduce Oxidative Stress.
Volume: 12
Pages: 690697
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Publication
26021615 | J:239193
First Author: Liu W
Year: 2015
Journal: Cell Res
Title: Park7 interacts with p47(phox) to direct NADPH oxidase-dependent ROS production and protect against sepsis.
Volume: 25
Issue: 6
Pages: 691-706
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Publication
36149763 | J:330146
First Author: Qu X
Year: 2022
Journal: Clin Transl Med
Title: PARK7 deficiency inhibits fatty acid β-oxidation via PTEN to delay liver regeneration after hepatectomy.
Volume: 12
Issue: 9
Pages: e1061
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Allele
Nlrp3<M10Btlr> | MGI:5789569
Name: NLR family, pyrin domain containing 3; mutation 10, Bruce Beutler
Allele Type: Chemically induced (ENU)
Attribute String: Not Specified
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Publication
35618940 | J:330143
First Author: Danileviciute E
Year: 2022
Journal: Nat Metab
Title: PARK7/DJ-1 promotes pyruvate dehydrogenase activity and maintains Treg homeostasis during ageing.
Volume: 4
Issue: 5
Pages: 589-607
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Publication
26422139 | J:243468
First Author: Jain D
Year: 2015
Journal: PLoS One
Title: DJ-1 Protects Pancreatic Beta Cells from Cytokine- and Streptozotocin-Mediated Cell Death.
Volume: 10
Issue: 9
Pages: e0138535
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Publication
28036277 | J:271676
First Author: Qiu B
Year: 2017
Journal: Oncotarget
Title: DJ-1 promotes development of DEN-induced hepatocellular carcinoma and proliferation of liver cancer cells.
Volume: 8
Issue: 5
Pages: 8499-8511
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Publication
36042578 | J:330144
 
First Author: Pan G
Year: 2022
Journal: Hum Exp Toxicol
Title: Parkinson's disease protein 7 protected against oxidative stress of myocardial infarction direct through p47phox and nicotinamide adenine dinucleotide phosphate oxidase 4.
Volume: 41
Pages: 9603271221124099
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Publication
26634899 | J:328377
 
First Author: Singh Y
Year: 2015
Journal: Sci Rep
Title: Differential effect of DJ-1/PARK7 on development of natural and induced regulatory T cells.
Volume: 5
Pages: 17723
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Publication
21068725 | J:168618
First Author: Guzman JN
Year: 2010
Journal: Nature
Title: Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1.
Volume: 468
Issue: 7324
Pages: 696-700
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Protein Coding Gene
MGP_CAROLIEiJ_G0026833 | -
Type: protein_coding_gene
Organism: Mus caroli
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Protein Coding Gene
MGP_129S1SvImJ_G0029157 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AJ_G0029122 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_AKRJ_G0029070 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_BALBcJ_G0029138 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C3HHeJ_G0028859 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGI_C57BL6J_2135637 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_C57BL6NJ_G0029587 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CASTEiJ_G0028272 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_CBAJ_G0028821 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_DBA2J_G0028970 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_FVBNJ_G0028934 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_LPJ_G0029060 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NODShiLtJ_G0028961 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_NZOHlLtJ_G0029619 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PWKPhJ_G0027992 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_WSBEiJ_G0028352 | -
Type: protein_coding_gene
Organism: mouse, laboratory
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Protein Coding Gene
MGP_PahariEiJ_G0029181 | -
Type: protein_coding_gene
Organism: Mus pahari
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Protein Coding Gene
MGP_SPRETEiJ_G0027826 | -
Type: protein_coding_gene
Organism: Mus spretus
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Publication
11223268 | J:69175
First Author: Taira T
Year: 2001
Journal: Gene
Title: Molecular cloning of human and mouse DJ-1 genes and identification of Sp1-dependent activation of the human DJ-1 promoter.
Volume: 263
Issue: 1-2
Pages: 285-92
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Publication
15784737 | J:97366
First Author: Kim RH
Year: 2005
Journal: Proc Natl Acad Sci U S A
Title: Hypersensitivity of DJ-1-deficient mice to 1-methyl-4-phenyl-1,2,3,6-tetrahydropyrindine (MPTP) and oxidative stress.
Volume: 102
Issue: 14
Pages: 5215-20
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Publication
17766438 | J:125021
First Author: Andres-Mateos E
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: DJ-1 gene deletion reveals that DJ-1 is an atypical peroxiredoxin-like peroxidase.
Volume: 104
Issue: 37
Pages: 14807-12
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Publication
19276172 | J:169981
First Author: Waak J
Year: 2009
Journal: FASEB J
Title: Regulation of astrocyte inflammatory responses by the Parkinson's disease-associated gene DJ-1.
Volume: 23
Issue: 8
Pages: 2478-89
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Publication
20186336 | J:157910
First Author: Krebiehl G
Year: 2010
Journal: PLoS One
Title: Reduced basal autophagy and impaired mitochondrial dynamics due to loss of Parkinson's disease-associated protein DJ-1.
Volume: 5
Issue: 2
Pages: e9367
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Publication
22523093 | J:212785
First Author: Lee JY
Year: 2012
Journal: Hum Mol Genet
Title: Human DJ-1 and its homologs are novel glyoxalases.
Volume: 21
Issue: 14
Pages: 3215-25
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Publication
22611253 | J:243391
First Author: Jain D
Year: 2012
Journal: J Mol Cell Biol
Title: Age- and diet-dependent requirement of DJ-1 for glucose homeostasis in mice with implications for human type 2 diabetes.
Volume: 4
Issue: 4
Pages: 221-30
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Publication
23847046 | J:202241
First Author: Kim KS
Year: 2013
Journal: Hum Mol Genet
Title: DJ-1 associates with lipid rafts by palmitoylation and regulates lipid rafts-dependent endocytosis in astrocytes.
Volume: 22
Issue: 23
Pages: 4805-17
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Publication
23792957 | J:201915
First Author: Björkblom B
Year: 2013
Journal: J Biol Chem
Title: Parkinson disease protein DJ-1 binds metals and protects against metal-induced cytotoxicity.
Volume: 288
Issue: 31
Pages: 22809-20
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Publication
12446870 | J:81230
First Author: Bonifati V
Year: 2003
Journal: Science
Title: Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism.
Volume: 299
Issue: 5604
Pages: 256-9
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Publication
24269020 | J:212735
First Author: Xiong R
Year: 2014
Journal: Neurobiol Aging
Title: MicroRNA-494 reduces DJ-1 expression and exacerbates neurodegeneration.
Volume: 35
Issue: 3
Pages: 705-14
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Publication
18187333 | J:141628
First Author: Chandran JS
Year: 2008
Journal: Neurobiol Dis
Title: Progressive behavioral deficits in DJ-1-deficient mice are associated with normal nigrostriatal function.
Volume: 29
Issue: 3
Pages: 505-14
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Publication
32826201 | J:317144
 
First Author: Upadhyay M
Year: 2020
Journal: Redox Biol
Title: Oxidative stress in the retina and retinal pigment epithelium (RPE): Role of aging, and DJ-1.
Volume: 37
Pages: 101623
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Publication
35713360 | J:337498
First Author: Mazza MC
Year: 2022
Journal: J Neurochem
Title: DJ-1 is not a deglycase and makes a modest contribution to cellular defense against methylglyoxal damage in neurons.
Volume: 162
Issue: 3
Pages: 245-261
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Publication
28088625 | J:271755
 
First Author: Bonilha VL
Year: 2017
Journal: Free Radic Biol Med
Title: Absence of DJ-1 causes age-related retinal abnormalities in association with increased oxidative stress.
Volume: 104
Pages: 226-237
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Publication
26215528 | J:230766
 
First Author: Bonilha VL
Year: 2015
Journal: Exp Eye Res
Title: Loss of DJ-1 elicits retinal abnormalities, visual dysfunction, and increased oxidative stress in mice.
Volume: 139
Pages: 22-36
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Publication
37839104 | J:342354
 
First Author: Chien CH
Year: 2023
Journal: Biochem Biophys Res Commun
Title: Growth of B16F10 cells is enhanced in DJ-1-deficiency pancreas.
Volume: 682
Pages: 359-364
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Publication
25706411 | J:226303
First Author: Chien CH
Year: 2015
Journal: PLoS One
Title: Local immunosuppressive microenvironment enhances migration of melanoma cells to lungs in DJ-1 knockout mice.
Volume: 10
Issue: 2
Pages: e0115827
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Publication
18003894 | J:141560
First Author: Aleyasin H
Year: 2007
Journal: Proc Natl Acad Sci U S A
Title: The Parkinson's disease gene DJ-1 is also a key regulator of stroke-induced damage.
Volume: 104
Issue: 47
Pages: 18748-53
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Publication
33246293 | J:330086
 
First Author: Amatullah H
Year: 2021
Journal: Redox Biol
Title: Protective function of DJ-1/PARK7 in lipopolysaccharide and ventilator-induced acute lung injury.
Volume: 38
Pages: 101796
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Publication
32999308 | J:296261
First Author: Singh Y
Year: 2020
Journal: Sci Rep
Title: DJ-1 (Park7) affects the gut microbiome, metabolites and the development of innate lymphoid cells (ILCs).
Volume: 10
Issue: 1
Pages: 16131
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Publication
20639397 | J:163635
First Author: Irrcher I
Year: 2010
Journal: Hum Mol Genet
Title: Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics.
Volume: 19
Issue: 19
Pages: 3734-46
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Publication
32715759 | J:298438
First Author: Leeds J
Year: 2020
Journal: Am J Physiol Renal Physiol
Title: Protective role of DJ-1 in endotoxin-induced acute kidney injury.
Volume: 319
Issue: 4
Pages: F654-F663
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Publication
32152416 | J:293948
First Author: Ozawa K
Year: 2020
Journal: Sci Rep
Title: DJ-1 is indispensable for the S-nitrosylation of Parkin, which maintains function of mitochondria.
Volume: 10
Issue: 1
Pages: 4377
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Publication
30696938 | J:275246
First Author: Kosmider B
Year: 2019
Journal: Sci Rep
Title: Impaired non-homologous end joining in human primary alveolar type II cells in emphysema.
Volume: 9
Issue: 1
Pages: 920
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Publication
31313618 | J:282213
First Author: Lin CR
Year: 2019
Journal: Am J Physiol Lung Cell Mol Physiol
Title: The relationship between DJ-1 and S100A8 in human primary alveolar type II cells in emphysema.
Volume: 317
Issue: 6
Pages: L791-L804
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Publication
29021755 | J:313562
 
First Author: Xu CY
Year: 2017
Journal: Front Aging Neurosci
Title: DJ-1 Inhibits α-Synuclein Aggregation by Regulating Chaperone-Mediated Autophagy.
Volume: 9
Pages: 308
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Publication
20133695 | J:157558
First Author: Aleyasin H
Year: 2010
Journal: Proc Natl Acad Sci U S A
Title: DJ-1 protects the nigrostriatal axis from the neurotoxin MPTP by modulation of the AKT pathway.
Volume: 107
Issue: 7
Pages: 3186-91
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Publication
23230227 | J:210281
First Author: Won KJ
Year: 2013
Journal: Cardiovasc Res
Title: DJ-1/park7 protects against neointimal formation via the inhibition of vascular smooth muscle cell growth.
Volume: 97
Issue: 3
Pages: 553-61
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Publication
24577080 | J:325806
 
First Author: Dongworth RK
Year: 2014
Journal: Cell Death Dis
Title: DJ-1 protects against cell death following acute cardiac ischemia-reperfusion injury.
Volume: 5
Pages: e1082
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Publication
16624565 | J:111114
First Author: Pisani A
Year: 2006
Journal: Neurobiol Dis
Title: Enhanced sensitivity of DJ-1-deficient dopaminergic neurons to energy metabolism impairment: role of Na+/K+ ATPase.
Volume: 23
Issue: 1
Pages: 54-60
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Publication
34593886 | J:313976
First Author: Pantner Y
Year: 2021
Journal: Sci Rep
Title: DJ-1 attenuates the glycation of mitochondrial complex I and complex III in the post-ischemic heart.
Volume: 11
Issue: 1
Pages: 19408
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Publication
23622116 | J:330096
 
First Author: Nguyen TA
Year: 2013
Journal: J Neuroinflammation
Title: Analysis of inflammation-related nigral degeneration and locomotor function in DJ-1(-/-) mice.
Volume: 10
Pages: 50
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Publication
27277679 | J:309640
First Author: Chen L
Year: 2016
Journal: Cell Death Dis
Title: DJ-1 deficiency attenuates expansion of liver progenitor cells through modulating the inflammatory and fibrogenic niches.
Volume: 7
Issue: 6
Pages: e2257
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Publication
23182168 | J:330090
First Author: Kim DK
Year: 2013
Journal: J Allergy Clin Immunol
Title: DJ-1 regulates mast cell activation and IgE-mediated allergic responses.
Volume: 131
Issue: 6
Pages: 1653-62
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Publication
24936441 | J:295003
 
First Author: Lopert P
Year: 2014
Journal: Redox Biol
Title: Brain mitochondria from DJ-1 knockout mice show increased respiration-dependent hydrogen peroxide consumption.
Volume: 2
Pages: 667-72
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Publication
22792356 | J:189646
First Author: Giaime E
Year: 2012
Journal: PLoS One
Title: Loss of DJ-1 does not affect mitochondrial respiration but increases ROS production and mitochondrial permeability transition pore opening.
Volume: 7
Issue: 7
Pages: e40501
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Publication
29142196 | J:255920
First Author: Kim HS
Year: 2017
Journal: Nat Commun
Title: DJ-1 controls bone homeostasis through the regulation of osteoclast differentiation.
Volume: 8
Issue: 1
Pages: 1519
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Publication
27766037 | J:313398
First Author: Yu Y
Year: 2016
Journal: Int J Biol Sci
Title: Deficiency of DJ-1 Ameliorates Liver Fibrosis through Inhibition of Hepatic ROS Production and Inflammation.
Volume: 12
Issue: 10
Pages: 1225-1235
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Publication
19683835 | J:168285
First Author: Shtifman A
Year: 2011
Journal: Neurobiol Aging
Title: Altered Ca2+ homeostasis in the skeletal muscle of DJ-1 null mice.
Volume: 32
Issue: 1
Pages: 125-32
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Publication
30443192 | J:286478
First Author: Xu M
Year: 2018
Journal: Int J Biol Sci
Title: DJ-1 Deficiency Protects Hepatic Steatosis by Enhancing Fatty Acid Oxidation in Mice.
Volume: 14
Issue: 13
Pages: 1892-1900
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Publication
24918637 | J:311710
First Author: Saito Y
Year: 2014
Journal: J Neuropathol Exp Neurol
Title: Immunostaining of oxidized DJ-1 in human and mouse brains.
Volume: 73
Issue: 7
Pages: 714-28
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Publication
25082883 | J:230247
First Author: Liu C
Year: 2014
Journal: Invest Ophthalmol Vis Sci
Title: Decreased DJ-1 leads to impaired Nrf2-regulated antioxidant defense and increased UV-A-induced apoptosis in corneal endothelial cells.
Volume: 55
Issue: 9
Pages: 5551-60
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Publication
22609282 | J:194438
First Author: Sheng C
Year: 2013
Journal: Neurobiol Aging
Title: DJ-1 deficiency perturbs microtubule dynamics and impairs striatal neurite outgrowth.
Volume: 34
Issue: 2
Pages: 489-98
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Publication
30104666 | J:323523
First Author: Mita Y
Year: 2018
Journal: Sci Rep
Title: Distribution of oxidized DJ-1 in Parkinson's disease-related sites in the brain and in the peripheral tissues: effects of aging and a neurotoxin.
Volume: 8
Issue: 1
Pages: 12056
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Publication
27108530 | J:250832
 
First Author: Shimizu Y
Year: 2016
Journal: J Mol Cell Cardiol
Title: DJ-1 protects the heart against ischemia-reperfusion injury by regulating mitochondrial fission.
Volume: 97
Pages: 56-66
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Publication
17535435 | J:134518
 
First Author: Yamaguchi H
Year: 2007
Journal: Mol Neurodegener
Title: Absence of dopaminergic neuronal degeneration and oxidative damage in aged DJ-1-deficient mice.
Volume: 2
Pages: 10
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Publication
28941803 | J:251231
 
First Author: Xue R
Year: 2017
Journal: Arch Biochem Biophys
Title: DJ-1 activates autophagy in the repression of cardiac hypertrophy.
Volume: 633
Pages: 124-132
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Publication
25822630 | J:229259
First Author: Lev N
Year: 2015
Journal: PLoS One
Title: DJ-1 knockout augments disease severity and shortens survival in a mouse model of ALS.
Volume: 10
Issue: 3
Pages: e0117190
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Publication
24816140 | J:212907
First Author: Sanchez-Padilla J
Year: 2014
Journal: Nat Neurosci
Title: Mitochondrial oxidant stress in locus coeruleus is regulated by activity and nitric oxide synthase.
Volume: 17
Issue: 6
Pages: 832-40
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Publication
28882997 | J:249953
First Author: Burbulla LF
Year: 2017
Journal: Science
Title: Dopamine oxidation mediates mitochondrial and lysosomal dysfunction in Parkinson's disease.
Volume: 357
Issue: 6357
Pages: 1255-1261
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Publication
20377612 | J:159608
First Author: Gan L
Year: 2010
Journal: Eur J Neurosci
Title: Keap1-Nrf2 activation in the presence and absence of DJ-1.
Volume: 31
Issue: 6
Pages: 967-77
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Publication
22492997 | J:184611
First Author: Im JY
Year: 2012
Journal: Hum Mol Genet
Title: DJ-1 induces thioredoxin 1 expression through the Nrf2 pathway.
Volume: 21
Issue: 13
Pages: 3013-24
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Publication
22941107 | J:191671
First Author: Goldberg JA
Year: 2012
Journal: Nat Neurosci
Title: Calcium entry induces mitochondrial oxidant stress in vagal neurons at risk in Parkinson's disease.
Volume: 15
Issue: 10
Pages: 1414-21
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Publication
30107296 | J:318528
 
First Author: Oh SE
Year: 2018
Journal: Redox Biol
Title: The Parkinson's disease gene product DJ-1 modulates miR-221 to promote neuronal survival against oxidative stress.
Volume: 19
Pages: 62-73
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Publication
23587484 | J:197361
First Author: Raman AV
Year: 2013
Journal: FEBS Lett
Title: Evidence of oxidative stress in young and aged DJ-1-deficient mice.
Volume: 587
Issue: 10
Pages: 1562-70
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Publication
17120294 | J:325312
First Author: Olzmann JA
Year: 2007
Journal: J Comp Neurol
Title: Selective enrichment of DJ-1 protein in primate striatal neuronal processes: implications for Parkinson's disease.
Volume: 500
Issue: 3
Pages: 585-99
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Publication
20089532 | J:158368
First Author: Ramsey CP
Year: 2010
Journal: Hum Mol Genet
Title: DJ-1 deficient mice demonstrate similar vulnerability to pathogenic Ala53Thr human alpha-syn toxicity.
Volume: 19
Issue: 8
Pages: 1425-37
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MouseMine is a collaboration between MGI at The Jackson Laboratory and the InterMine project at the Cambridge Systems Biology Centre. MouseMine is funded through a grant from the NIH/NHGRI.The Jackson Laboratory makes no representation about the suitability or accuracy of this software or data for any purpose, and makes no warranties, either express or implied, including merchantability and fitness for a particular purpose or that the use of this software or data will not infringe any third party patents, copyrights, trademarks, or other rights. the software and data are provided "as is". This software and data are provided to enhance knowledge and encourage progress in the scientific community and are to be used only for research and educational purposes. Any reproduction or use for commercial purpose is prohibited without the prior express written permission of the Jackson Laboratory.

Copyright © 2017 by The Jackson Laboratory. All Rights Reserved

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