Type |
Details |
Score |
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
frog, western clawed |
|
•
•
•
•
•
|
Gene |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
dog, domestic |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chimpanzee |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
cattle |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
chicken |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
macaque, rhesus |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Gene |
Type: |
gene |
Organism: |
human |
|
•
•
•
•
•
|
Publication |
First Author: |
Schumacher S |
Year: |
2024 |
Journal: |
Commun Biol |
Title: |
The mitochondrial protease PARL is required for spermatogenesis. |
Volume: |
7 |
Issue: |
1 |
Pages: |
44 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeyaraju DV |
Year: |
2011 |
Journal: |
Cell Death Differ |
Title: |
Structural and mechanistic basis of Parl activity and regulation. |
Volume: |
18 |
Issue: |
9 |
Pages: |
1531-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Meissner C |
Year: |
2011 |
Journal: |
J Neurochem |
Title: |
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. |
Volume: |
117 |
Issue: |
5 |
Pages: |
856-67 |
|
•
•
•
•
•
|
Publication |
First Author: |
Shi G |
Year: |
2011 |
Journal: |
Hum Mol Genet |
Title: |
Functional alteration of PARL contributes to mitochondrial dysregulation in Parkinson's disease. |
Volume: |
20 |
Issue: |
10 |
Pages: |
1966-74 |
|
•
•
•
•
•
|
Publication |
First Author: |
Cipolat S |
Year: |
2006 |
Journal: |
Cell |
Title: |
Mitochondrial rhomboid PARL regulates cytochrome c release during apoptosis via OPA1-dependent cristae remodeling. |
Volume: |
126 |
Issue: |
1 |
Pages: |
163-75 |
|
•
•
•
•
•
|
Publication |
First Author: |
Chao JR |
Year: |
2008 |
Journal: |
Nature |
Title: |
Hax1-mediated processing of HtrA2 by Parl allows survival of lymphocytes and neurons. |
Volume: |
452 |
Issue: |
7183 |
Pages: |
98-102 |
|
•
•
•
•
•
|
Publication |
First Author: |
Radaelli E |
Year: |
2023 |
Journal: |
Elife |
Title: |
Mitochondrial defects caused by PARL deficiency lead to arrested spermatogenesis and ferroptosis. |
Volume: |
12 |
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Spinazzi M |
Year: |
2019 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
PARL deficiency in mouse causes Complex III defects, coenzyme Q depletion, and Leigh-like syndrome. |
Volume: |
116 |
Issue: |
1 |
Pages: |
277-286 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jeyaraju DV |
Year: |
2009 |
Journal: |
Cell Death Differ |
Title: |
Hax1 lacks BH modules and is peripherally associated to heavy membranes: implications for Omi/HtrA2 and PARL activity in the regulation of mitochondrial stress and apoptosis. |
Volume: |
16 |
Issue: |
12 |
Pages: |
1622-9 |
|
•
•
•
•
•
|
Strain |
Attribute String: |
congenic, mutant strain, targeted mutation |
|
•
•
•
•
•
|
Publication |
First Author: |
Civitarese AE |
Year: |
2010 |
Journal: |
Cell Metab |
Title: |
Regulation of skeletal muscle oxidative capacity and insulin signaling by the mitochondrial rhomboid protease PARL. |
Volume: |
11 |
Issue: |
5 |
Pages: |
412-26 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deas E |
Year: |
2011 |
Journal: |
Hum Mol Genet |
Title: |
PINK1 cleavage at position A103 by the mitochondrial protease PARL. |
Volume: |
20 |
Issue: |
5 |
Pages: |
867-79 |
|
•
•
•
•
•
|
Publication |
First Author: |
Sanjuán Szklarz LK |
Year: |
2012 |
Journal: |
Biochim Biophys Acta |
Title: |
The antiapoptotic OPA1/Parl couple participates in mitochondrial adaptation to heat shock. |
Volume: |
1817 |
Issue: |
10 |
Pages: |
1886-93 |
|
•
•
•
•
•
|
Publication |
First Author: |
Deshwal S |
Year: |
2023 |
Journal: |
Nat Cell Biol |
Title: |
Mitochondria regulate intracellular coenzyme Q transport and ferroptotic resistance via STARD7. |
Volume: |
25 |
Issue: |
2 |
Pages: |
246-257 |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus caroli |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
mouse, laboratory |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus pahari |
|
•
•
•
•
•
|
Protein Coding Gene |
Type: |
protein_coding_gene |
Organism: |
Mus spretus |
|
•
•
•
•
•
|
Publication |
First Author: |
McQuibban GA |
Year: |
2006 |
Journal: |
Curr Biol |
Title: |
Normal mitochondrial dynamics requires rhomboid-7 and affects Drosophila lifespan and neuronal function. |
Volume: |
16 |
Issue: |
10 |
Pages: |
982-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Jin SM |
Year: |
2010 |
Journal: |
J Cell Biol |
Title: |
Mitochondrial membrane potential regulates PINK1 import and proteolytic destabilization by PARL. |
Volume: |
191 |
Issue: |
5 |
Pages: |
933-42 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics and the Europhenome Mouse Phenotyping Resource |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Obtaining and Loading Phenotype Annotations from Europhenome |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Pagliarini DJ |
Year: |
2008 |
Journal: |
Cell |
Title: |
A mitochondrial protein compendium elucidates complex I disease biology. |
Volume: |
134 |
Issue: |
1 |
Pages: |
112-23 |
|
•
•
•
•
•
|
Publication |
First Author: |
The Jackson Laboratory Backcross DNA Panel Mapping Resource |
Year: |
1999 |
Journal: |
Database Release |
Title: |
JAX BSS Panel Mapping Data |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information Editorial Staff Collaboration |
Year: |
2001 |
|
Title: |
LocusLink Collaboration |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Ko MS |
Year: |
2000 |
Journal: |
Development |
Title: |
Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. |
Volume: |
127 |
Issue: |
8 |
Pages: |
1737-49 |
|
•
•
•
•
•
|
Publication |
First Author: |
Friedel RH |
Year: |
2007 |
Journal: |
Brief Funct Genomic Proteomic |
Title: |
EUCOMM--the European conditional mouse mutagenesis program. |
Volume: |
6 |
Issue: |
3 |
Pages: |
180-5 |
|
•
•
•
•
•
|
Publication |
First Author: |
Velocigene |
Year: |
2008 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the KOMP project by Velocigene (Regeneron Pharmaceuticals) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Shanghai Model Organisms Center |
Year: |
2017 |
Journal: |
MGI Direct Data Submission |
Title: |
Information obtained from the Shanghai Model Organisms Center (SMOC), Shanghai, China |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Hansen GM |
Year: |
2008 |
Journal: |
Genome Res |
Title: |
Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. |
Volume: |
18 |
Issue: |
10 |
Pages: |
1670-9 |
|
•
•
•
•
•
|
Publication |
First Author: |
Helmholtz Zentrum Muenchen GmbH |
Year: |
2010 |
Journal: |
MGI Direct Data Submission |
Title: |
Alleles produced for the EUCOMM and EUCOMMTools projects by the Helmholtz Zentrum Muenchen GmbH (Hmgu) |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
UniProt-GOA |
Year: |
2012 |
|
Title: |
Gene Ontology annotation based on UniProtKB/Swiss-Prot Subcellular Location vocabulary mapping, accompanied by conservative changes to GO terms applied by UniProt |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2003 |
|
Title: |
MGI Sequence Curation Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Carninci P |
Year: |
2005 |
Journal: |
Science |
Title: |
The transcriptional landscape of the mammalian genome. |
Volume: |
309 |
Issue: |
5740 |
Pages: |
1559-63 |
|
•
•
•
•
•
|
Publication |
First Author: |
Adams DJ |
Year: |
2024 |
Journal: |
Nature |
Title: |
Genetic determinants of micronucleus formation in vivo. |
Volume: |
627 |
Issue: |
8002 |
Pages: |
130-136 |
|
•
•
•
•
•
|
Publication |
First Author: |
MGD Nomenclature Committee |
Year: |
1995 |
|
Title: |
Nomenclature Committee Use |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Zambrowicz BP |
Year: |
2003 |
Journal: |
Proc Natl Acad Sci U S A |
Title: |
Wnk1 kinase deficiency lowers blood pressure in mice: a gene-trap screen to identify potential targets for therapeutic intervention. |
Volume: |
100 |
Issue: |
24 |
Pages: |
14109-14 |
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and National Center for Biotechnology Information (NCBI) |
Year: |
2008 |
Journal: |
Database Download |
Title: |
Mouse Gene Trap Data Load from dbGSS |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
AgBase, BHF-UCL, Parkinson's UK-UCL, dictyBase, HGNC, Roslin Institute, FlyBase and UniProtKB curators |
Year: |
2011 |
|
Title: |
Manual transfer of experimentally-verified manual GO annotation data to orthologs by curator judgment of sequence similarity |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
GOA curators |
Year: |
2016 |
|
Title: |
Automatic transfer of experimentally verified manual GO annotation data to orthologs using Ensembl Compara |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
The Gene Ontology Consortium |
Year: |
2010 |
|
Title: |
Automated transfer of experimentally-verified manual GO annotation data to mouse-human orthologs |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2002 |
|
Title: |
Mouse Genome Informatics Computational Sequence to Gene Associations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome U74 Array Platform (A, B, C v2). |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
MGI Genome Annotation Group and UniGene Staff |
Year: |
2015 |
Journal: |
Database Download |
Title: |
MGI-UniGene Interconnection Effort |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Marc Feuermann, Huaiyu Mi, Pascale Gaudet, Dustin Ebert, Anushya Muruganujan, Paul Thomas |
Year: |
2010 |
|
Title: |
Annotation inferences using phylogenetic trees |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Database and National Center for Biotechnology Information |
Year: |
2000 |
Journal: |
Database Release |
Title: |
Entrez Gene Load |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Gene 1.0 ST Array Platform |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics (MGI) and The National Center for Biotechnology Information (NCBI) |
Year: |
2010 |
Journal: |
Database Download |
Title: |
Consensus CDS project |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Group |
Year: |
2003 |
Journal: |
Database Procedure |
Title: |
Automatic Encodes (AutoE) Reference |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Bairoch A |
Year: |
1999 |
Journal: |
Database Release |
Title: |
SWISS-PROT Annotated protein sequence database |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and Loading Genome Assembly Coordinates from Ensembl Annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics |
Year: |
2010 |
Journal: |
Database Release |
Title: |
Protein Ontology Association Load. |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2005 |
|
Title: |
Obtaining and loading genome assembly coordinates from NCBI annotations |
|
|
|
|
•
•
•
•
•
|
Publication |
First Author: |
Mouse Genome Informatics Scientific Curators |
Year: |
2009 |
Journal: |
Database Download |
Title: |
Mouse Microarray Data Integration in Mouse Genome Informatics, the Affymetrix GeneChip Mouse Genome 430 2.0 Array Platform |
|
|
|
|
•
•
•
•
•
|
Strain |
Attribute String: |
targeted mutation, mutant strain, congenic |
|
•
•
•
•
•
|
Protein |
Organism: |
Mus musculus/domesticus |
Length: |
377
 |
Fragment?: |
false |
|
•
•
•
•
•
|
Publication |
First Author: |
Sun Y |
Year: |
2017 |
Journal: |
Biochim Biophys Acta |
Title: |
MLF1 is a proapoptotic antagonist of HOP complex-mediated survival. |
Volume: |
1864 |
Issue: |
4 |
Pages: |
719-727 |
|
•
•
•
•
•
|
Publication |
First Author: |
Liu T |
Year: |
2023 |
Journal: |
Cells |
Title: |
Disruption of Mitophagy Flux through the PARL-PINK1 Pathway by CHCHD10 Mutations or CHCHD10 Depletion. |
Volume: |
12 |
Issue: |
24 |
|
|
•
•
•
•
•
|
Publication |
First Author: |
Horibata Y |
Year: |
2020 |
Journal: |
Sci Rep |
Title: |
The phosphatidylcholine transfer protein StarD7 is important for myogenic differentiation in mouse myoblast C2C12 cells and human primary skeletal myoblasts. |
Volume: |
10 |
Issue: |
1 |
Pages: |
2845 |
|
•
•
•
•
•
|