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Search results 1 to 100 out of 745 for Parp1

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Type Details Score
Gene
Type: gene
Organism: Homo sapiens
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Gene
Type: gene
Organism: Homo sapiens
Publication
First Author: Claybon A
Year: 2010
Journal: Nucleic Acids Res
Title: PARP1 suppresses homologous recombination events in mice in vivo.
Volume: 38
Issue: 21
Pages: 7538-45
Publication
First Author: Hoch NC
Year: 2017
Journal: Nature
Title: XRCC1 mutation is associated with PARP1 hyperactivation and cerebellar ataxia.
Volume: 541
Issue: 7635
Pages: 87-91
Publication
First Author: Gomez M
Year: 2006
Journal: Mol Biol Cell
Title: PARP1 Is a TRF2-associated poly(ADP-ribose)polymerase and protects eroded telomeres.
Volume: 17
Issue: 4
Pages: 1686-96
Publication
First Author: von Lukowicz T
Year: 2008
Journal: Cardiovasc Res
Title: PARP1 is required for adhesion molecule expression in atherogenesis.
Volume: 78
Issue: 1
Pages: 158-66
Publication
First Author: Zuo H
Year: 2020
Journal: Nat Commun
Title: Differential regulation of breast cancer bone metastasis by PARP1 and PARP2.
Volume: 11
Issue: 1
Pages: 1578
Publication
First Author: Sahaboglu A
Year: 2010
Journal: PLoS One
Title: PARP1 gene knock-out increases resistance to retinal degeneration without affecting retinal function.
Volume: 5
Issue: 11
Pages: e15495
Publication  
First Author: Ke Y
Year: 2017
Journal: Nat Commun
Title: PARP1 promotes gene expression at the post-transcriptiona level by modulating the RNA-binding protein HuR.
Volume: 8
Pages: 14632
Publication
First Author: Doege CA
Year: 2012
Journal: Nature
Title: Early-stage epigenetic modification during somatic cell reprogramming by Parp1 and Tet2.
Volume: 488
Issue: 7413
Pages: 652-5
Publication
First Author: Sullivan-Reed K
Year: 2018
Journal: Cell Rep
Title: Simultaneous Targeting of PARP1 and RAD52 Triggers Dual Synthetic Lethality in BRCA-Deficient Tumor Cells.
Volume: 23
Issue: 11
Pages: 3127-3136
Publication
First Author: Robert I
Year: 2009
Journal: J Exp Med
Title: Parp1 facilitates alternative NHEJ, whereas Parp2 suppresses IgH/c-myc translocations during immunoglobulin class switch recombination.
Volume: 206
Issue: 5
Pages: 1047-56
Publication
First Author: Erener S
Year: 2012
Journal: Mol Cell
Title: Inflammasome-activated caspase 7 cleaves PARP1 to enhance the expression of a subset of NF-κB target genes.
Volume: 46
Issue: 2
Pages: 200-11
Publication
First Author: Wang X
Year: 2007
Journal: Cell Death Differ
Title: Haploinsufficiency of Parp1 accelerates Brca1-associated centrosome amplification, telomere shortening, genetic instability, apoptosis, and embryonic lethality.
Volume: 14
Issue: 5
Pages: 924-31
Publication
First Author: Gao F
Year: 2009
Journal: J Biol Chem
Title: PARP1 poly(ADP-ribosyl)ates Sox2 to control Sox2 protein levels and FGF4 expression during embryonic stem cell differentiation.
Volume: 284
Issue: 33
Pages: 22263-73
Publication
First Author: Rybanska I
Year: 2013
Journal: Oncogene
Title: PARP1 and DNA-PKcs synergize to suppress p53 mutation and telomere fusions during T-lineage lymphomagenesis.
Volume: 32
Issue: 14
Pages: 1761-71
Publication
First Author: Knittel G
Year: 2017
Journal: Nat Commun
Title: Two mouse models reveal an actionable PARP1 dependence in aggressive chronic lymphocytic leukemia.
Volume: 8
Issue: 1
Pages: 153
Publication
First Author: Zampieri M
Year: 2009
Journal: PLoS One
Title: Parp1 localizes within the Dnmt1 promoter and protects its unmethylated state by its enzymatic activity.
Volume: 4
Issue: 3
Pages: e4717
Publication
First Author: Na TY
Year: 2016
Journal: Oncogene
Title: Interaction of hepatitis B virus X protein with PARP1 results in inhibition of DNA repair in hepatocellular carcinoma.
Volume: 35
Issue: 41
Pages: 5435-5445
Publication
First Author: Meyer-Ficca ML
Year: 2011
Journal: Biol Reprod
Title: Poly(ADP-ribose) polymerases PARP1 and PARP2 modulate topoisomerase II beta (TOP2B) function during chromatin condensation in mouse spermiogenesis.
Volume: 84
Issue: 5
Pages: 900-9
Publication
First Author: Goldberg MS
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Nanoparticle-mediated delivery of siRNA targeting Parp1 extends survival of mice bearing tumors derived from Brca1-deficient ovarian cancer cells.
Volume: 108
Issue: 2
Pages: 745-50
Publication
First Author: Schuhwerk H
Year: 2017
Journal: Nucleic Acids Res
Title: Kinetics of poly(ADP-ribosyl)ation, but not PARP1 itself, determines the cell fate in response to DNA damage in vitro and in vivo.
Volume: 45
Issue: 19
Pages: 11174-11192
Publication
First Author: Pacchierotti F
Year: 2011
Journal: Mutat Res
Title: In vivo repair of DNA damage induced by X-rays in the early stages of mouse fertilization, and the influence of maternal PARP1 ablation.
Volume: 714
Issue: 1-2
Pages: 44-52
Publication
First Author: Szczesny B
Year: 2014
Journal: Nucleic Acids Res
Title: Opposing roles of mitochondrial and nuclear PARP1 in the regulation of mitochondrial and nuclear DNA integrity: implications for the regulation of mitochondrial function.
Volume: 42
Issue: 21
Pages: 13161-73
Publication
First Author: Van Meter M
Year: 2016
Journal: Cell Rep
Title: JNK Phosphorylates SIRT6 to Stimulate DNA Double-Strand Break Repair in Response to Oxidative Stress by Recruiting PARP1 to DNA Breaks.
Volume: 16
Issue: 10
Pages: 2641-2650
GXD Expression
Probe: MGI:5812130
Assay Type: Immunohistochemistry
Annotation Date: 2016-12-15
Strength: Present
Sex: Not Specified
Emaps: EMAPS:160398
Pattern: Single cells
Stage: TS08
Assay Id: MGI:5812131
Age: embryonic day 5.5
Image: 3B Cdh1-/-
Note: There were more than five cleaved Parp1 cells in 7/7 embryos.
Detected: true
Specimen Num: 2
Gene
Type: gene
Organism: Rattus norvegicus
Gene
Type: gene
Organism: Danio rerio
GXD Expression
Probe: MGI:5812130
Assay Type: Immunohistochemistry
Annotation Date: 2016-12-15
Strength: Trace
Sex: Not Specified
Emaps: EMAPS:160398
Pattern: Single cells
Stage: TS08
Assay Id: MGI:5812131
Age: embryonic day 5.5
Image: 3B Control
Note: There were no cleaved Parp1 cells in 16/20 embryos and 1 or 2 cleaved Parp cells in 4/20 embryos (shown).
Detected: true
Specimen Num: 1
Publication
First Author: Mangerich A
Year: 2009
Journal: Transgenic Res
Title: A caveat in mouse genetic engineering: ectopic gene targeting in ES cells by bidirectional extension of the homology arms of a gene replacement vector carrying human PARP-1.
Volume: 18
Issue: 2
Pages: 261-79
Publication
First Author: Ju C
Year: 2019
Journal: Biochem Biophys Res Commun
Title: Poly(ADP-ribose) Polymerase-1 is required for hepatocyte proliferation and liver regeneration in mice.
Volume: 511
Issue: 3
Pages: 531-535
Publication
First Author: Altmeyer M
Year: 2010
Journal: Infect Immun
Title: Absence of poly(ADP-ribose) polymerase 1 delays the onset of Salmonella enterica serovar Typhimurium-induced gut inflammation.
Volume: 78
Issue: 8
Pages: 3420-31
Publication
First Author: Spagnolo L
Year: 2012
Journal: Nucleic Acids Res
Title: Visualization of a DNA-PK/PARP1 complex.
Volume: 40
Issue: 9
Pages: 4168-77
Publication
First Author: Hieb AR
Year: 2012
Journal: Nucleic Acids Res
Title: Fluorescence strategies for high-throughput quantification of protein interactions.
Volume: 40
Issue: 5
Pages: e33
Publication
First Author: Huang D
Year: 2020
Journal: Mol Cell
Title: Functional Interplay between Histone H2B ADP-Ribosylation and Phosphorylation Controls Adipogenesis.
Volume: 79
Issue: 6
Pages: 934-949.e14
Publication
First Author: Mao Z
Year: 2011
Journal: Science
Title: SIRT6 promotes DNA repair under stress by activating PARP1.
Volume: 332
Issue: 6036
Pages: 1443-6
Publication
First Author: Allocca M
Year: 2017
Journal: Oncotarget
Title: PARP inhibitors protect against sex- and AAG-dependent alkylation-induced neural degeneration.
Volume: 8
Issue: 40
Pages: 68707-68720
Publication
First Author: Nieborowska-Skorska M
Year: 2017
Journal: J Clin Invest
Title: Gene expression and mutation-guided synthetic lethality eradicates proliferating and quiescent leukemia cells.
Volume: 127
Issue: 6
Pages: 2392-2406
Publication
First Author: Brochier C
Year: 2015
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) polymerase 1 is a novel target to promote axonal regeneration.
Volume: 112
Issue: 49
Pages: 15220-5
Publication  
First Author: Wang X
Year: 2016
Journal: eNeuro
Title: Inhibition of Poly-ADP-Ribosylation Fails to Increase Axonal Regeneration or Improve Functional Recovery after Adult Mammalian CNS Injury.
Volume: 3
Issue: 6
Publication
First Author: Louro H
Year: 2008
Journal: Mutat Res
Title: Mutagenic effects of poly (ADP-ribose) polymerase-1 deficiency in transgenic mice.
Volume: 640
Issue: 1-2
Pages: 82-8
Publication
First Author: Kim J
Year: 2011
Journal: Am J Physiol Renal Physiol
Title: Loss of poly(ADP-ribose) polymerase 1 attenuates renal fibrosis and inflammation during unilateral ureteral obstruction.
Volume: 301
Issue: 2
Pages: F450-9
Publication  
First Author: Vallerini GP
Year: 2020
Journal: Neuroscience
Title: Modulation of Poly ADP Ribose Polymerase (PARP) Levels and Activity by Alcohol Binge-Like Drinking in Male Mice.
Volume: 448
Pages: 1-13
Publication
First Author: Wang C
Year: 2013
Journal: Mol Cell Biol
Title: Poly(ADP-ribose) polymerase 1 promotes oxidative-stress-induced liver cell death via suppressing farnesoid X receptor α.
Volume: 33
Issue: 22
Pages: 4492-503
Publication
First Author: Lee Y
Year: 2013
Journal: Nat Neurosci
Title: Parthanatos mediates AIMP2-activated age-dependent dopaminergic neuronal loss.
Volume: 16
Issue: 10
Pages: 1392-400
Publication
First Author: Lai YS
Year: 2012
Journal: Proc Natl Acad Sci U S A
Title: SRY (sex determining region Y)-box2 (Sox2)/poly ADP-ribose polymerase 1 (Parp1) complexes regulate pluripotency.
Volume: 109
Issue: 10
Pages: 3772-7
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Publication
First Author: Lee SS
Year: 2015
Journal: Cell Rep
Title: ATM Kinase Is Required for Telomere Elongation in Mouse and Human Cells.
Volume: 13
Issue: 8
Pages: 1623-32
Publication  
First Author: Ding X
Year: 2016
Journal: Nat Commun
Title: Synthetic viability by BRCA2 and PARP1/ARTD1 deficiencies.
Volume: 7
Pages: 12425
Publication
First Author: Boehler C
Year: 2011
Journal: Proc Natl Acad Sci U S A
Title: Poly(ADP-ribose) polymerase 3 (PARP3), a newcomer in cellular response to DNA damage and mitotic progression.
Volume: 108
Issue: 7
Pages: 2783-8
Publication
First Author: Calvo JA
Year: 2013
Journal: PLoS Genet
Title: Aag DNA glycosylase promotes alkylation-induced tissue damage mediated by Parp1.
Volume: 9
Issue: 4
Pages: e1003413
Publication
First Author: Lin CP
Year: 2008
Journal: J Biol Chem
Title: A ubiquitin-proteasome pathway for the repair of topoisomerase I-DNA covalent complexes.
Volume: 283
Issue: 30
Pages: 21074-83
Publication  
First Author: Du W
Year: 2016
Journal: Sci Rep
Title: Hyper-active non-homologous end joining selects for synthetic lethality resistant and pathological Fanconi anemia hematopoietic stem and progenitor cells.
Volume: 6
Pages: 22167
Publication
First Author: Malireddi RK
Year: 2010
Journal: J Immunol
Title: Cutting edge: proteolytic inactivation of poly(ADP-ribose) polymerase 1 by the Nlrp3 and Nlrc4 inflammasomes.
Volume: 185
Issue: 6
Pages: 3127-30
Publication
First Author: Zhao B
Year: 2015
Journal: Cell Stem Cell
Title: Filia Is an ESC-Specific Regulator of DNA Damage Response and Safeguards Genomic Stability.
Volume: 16
Issue: 6
Pages: 684-98
Publication
First Author: Wyrsch P
Year: 2012
Journal: Mol Cell Biol
Title: Cell death and autophagy under oxidative stress: roles of poly(ADP-Ribose) polymerases and Ca(2+).
Volume: 32
Issue: 17
Pages: 3541-53
Publication
First Author: Li G
Year: 2012
Journal: Diabetes
Title: Marrow-derived cells regulate the development of early diabetic retinopathy and tactile allodynia in mice.
Volume: 61
Issue: 12
Pages: 3294-303
Publication
First Author: Larmonier CB
Year: 2016
Journal: J Biol Chem
Title: Transcriptional Reprogramming and Resistance to Colonic Mucosal Injury in Poly(ADP-ribose) Polymerase 1 (PARP1)-deficient Mice.
Volume: 291
Issue: 17
Pages: 8918-30
Publication
First Author: Lu P
Year: 2014
Journal: J Neurosci
Title: Poly(ADP-ribose) polymerase-1 causes mitochondrial damage and neuron death mediated by Bnip3.
Volume: 34
Issue: 48
Pages: 15975-87
Publication
First Author: Min W
Year: 2010
Journal: Carcinogenesis
Title: Deletion of the nuclear isoform of poly(ADP-ribose) glycohydrolase (PARG) reveals its function in DNA repair, genomic stability and tumorigenesis.
Volume: 31
Issue: 12
Pages: 2058-65
Publication
First Author: Joshi A
Year: 2016
Journal: Cell Death Differ
Title: Nuclear ULK1 promotes cell death in response to oxidative stress through PARP1.
Volume: 23
Issue: 2
Pages: 216-30
Publication
First Author: Rajamohan SB
Year: 2009
Journal: Mol Cell Biol
Title: SIRT1 promotes cell survival under stress by deacetylation-dependent deactivation of poly(ADP-ribose) polymerase 1.
Volume: 29
Issue: 15
Pages: 4116-29
Publication
First Author: Matsushima S
Year: 2011
Journal: Biochem Biophys Res Commun
Title: An Mdm2 antagonist, Nutlin-3a, induces p53-dependent and proteasome-mediated poly(ADP-ribose) polymerase1 degradation in mouse fibroblasts.
Volume: 407
Issue: 3
Pages: 557-61
Publication
First Author: Zhu Y
Year: 2013
Journal: Toxicol Appl Pharmacol
Title: Modulation of farnesoid X receptor results in post-translational modification of poly (ADP-ribose) polymerase 1 in the liver.
Volume: 266
Issue: 2
Pages: 260-6
Publication
First Author: Kleppa L
Year: 2012
Journal: Nucleic Acids Res
Title: Kinetics of endogenous mouse FEN1 in base excision repair.
Volume: 40
Issue: 18
Pages: 9044-59
Publication
First Author: Orsburn B
Year: 2010
Journal: Mol Cell Biol
Title: Differential requirement for H2AX and 53BP1 in organismal development and genome maintenance in the absence of poly(ADP)ribosyl polymerase 1.
Volume: 30
Issue: 10
Pages: 2341-52
Publication
First Author: Lee SG
Year: 2020
Journal: EMBO Rep
Title: Ewing sarcoma protein promotes dissociation of poly(ADP-ribose) polymerase 1 from chromatin.
Volume: 21
Issue: 11
Pages: e48676
Publication
First Author: Zhang Y
Year: 2016
Journal: Am J Pathol
Title: Inhibition of Poly(ADP-Ribose) Polymerase-1 Protects Chronic Alcoholic Liver Injury.
Volume: 186
Issue: 12
Pages: 3117-3130
Publication
First Author: Rybanska-Spaeder I
Year: 2014
Journal: PLoS One
Title: 53BP1 mediates the fusion of mammalian telomeres rendered dysfunctional by DNA-PKcs loss or inhibition.
Volume: 9
Issue: 9
Pages: e108731
Publication  
First Author: Mochizuki AL
Year: 2017
Journal: Mol Cell Biol
Title: PARI Regulates Stalled Replication Fork Processing To Maintain Genome Stability upon Replication Stress in Mice.
Volume: 37
Issue: 23
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus caroli
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus musculus
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus pahari
Protein Coding Gene
Type: protein_coding_gene
Organism: Mus spretus
Publication
First Author: Sallmann FR
Year: 2000
Journal: J Biol Chem
Title: Characterization of sPARP-1. An alternative product of PARP-1 gene with poly(ADP-ribose) polymerase activity independent of DNA strand breaks.
Volume: 275
Issue: 20
Pages: 15504-11
Publication
First Author: Auer B
Year: 1995
Journal: Biochimie
Title: On the biological role of the nuclear polymerizing NAD+: protein(ADP-ribosyl) transferase (ADPRT): ADPRT from Dictyostelium discoideum and inactivation of the ADPRT gene in the mouse.
Volume: 77
Issue: 6
Pages: 444-9
Publication
First Author: de Murcia G
Year: 1994
Journal: Trends Biochem Sci
Title: Poly(ADP-ribose) polymerase: a molecular nick-sensor.
Volume: 19
Issue: 4
Pages: 172-6
Publication
First Author: Shibata A
Year: 2009
Journal: Mutat Res
Title: Role of Parp-1 in suppressing spontaneous deletion mutation in the liver and brain of mice at adolescence and advanced age.
Volume: 664
Issue: 1-2
Pages: 20-7
Publication
First Author: Shibata A
Year: 2005
Journal: Oncogene
Title: Parp-1 deficiency causes an increase of deletion mutations and insertions/rearrangements in vivo after treatment with an alkylating agent.
Volume: 24
Issue: 8
Pages: 1328-37
Publication
First Author: Phulwani NK
Year: 2008
Journal: J Neurochem
Title: Poly (ADP-ribose) polymerases (PARPs) 1-3 regulate astrocyte activation.
Volume: 106
Issue: 2
Pages: 578-90
Publication
First Author: Liaudet L
Year: 2000
Journal: Proc Natl Acad Sci U S A
Title: Protection against hemorrhagic shock in mice genetically deficient in poly(ADP-ribose)polymerase.
Volume: 97
Issue: 18
Pages: 10203-8
Publication
First Author: Eliasson MJ
Year: 1997
Journal: Nat Med
Title: Poly(ADP-ribose) polymerase gene disruption renders mice resistant to cerebral ischemia.
Volume: 3
Issue: 10
Pages: 1089-95